Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CTPS1 1503 GLUTAMINE CHEMBL930 antagonist DrugBank 17331943, 17137369, 16427816

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CTPS1 rs12067645 AA + AG ara-CTP metabolism/PK yes Genotypes AA + AG is associated with increased concentrations of ara-CTP in children with Leukemia, Myeloid, Acute as compared to genotype GG. 30088438 1449752045
CTPS1 rs4364871 CT + TT ara-CTP metabolism/PK yes Genotypes CT + TT is associated with decreased concentrations of ara-CTP in children with Leukemia, Myeloid, Acute as compared to genotype CC. 30088438 1449752025