Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CRH 1392 CHEMBL1230906 CHEMBL1230906 DrugBank 10592235
CRH 1392 CORTICOTROPIN CHEMBL1201610 agonist DrugBank 16523405, 16503922, 16534240, 16467980, 16472586
CRH 1392 D-PHENYLALANINE CHEMBL379630 DrugBank 10592235
CRH 1392 NALOXONE CHEMBL80 NCI 2542355
CRH 1392 ROSIGLITAZONE CHEMBL121 NCI 15279069

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CRH rs4737771 C antidepressants efficacy yes Identity of minor allele not specified, so minor allele of dbSNP used here (C). Remission considered to be score < or equal to 7 at discharge of the Hamilton Rating Scale for Depression (HRSD17). Patients measured at admission and discharge, 4-6 weeks later. Specific antidepressants not listed. Allele C is associated with decreased response to antidepressants in people with Depressive Disorder, Major as compared to allele T. 27091189 1447983268