PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
VAC14	5	PRR20A	0	two hybrid	Rolland T (2014)	1
RBPMS	0	C1orf94	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
ATXN1	2	RBPMS	0	two hybrid, affinity chromatography technology, two hybrid	Lim J (2006), Lim J (2006), Rolland T (2014)	3
ROR2	0	C1orf94	1	two hybrid	Rolland T (2014)	1
NEDD9	3	PRR20A	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	POGZ	49	two hybrid	Rolland T (2014)	1
FOXP3	1	PRR20A	0	two hybrid	Rolland T (2014)	1
PITX1	2	PRR20A	0	two hybrid	Corominas R (2014)	1
DAZAP2	1	PRR20A	0	two hybrid	Rolland T (2014)	1
GATA2	0	PRR20A	0	two hybrid	Rolland T (2014)	1
NEDD9	3	RBPMS	0	two hybrid	Rolland T (2014)	1
RBFOX1	1	DAB1	1	two hybrid	Corominas R (2014)	1
ATXN1	2	ZNF488	0	two hybrid	Lim J (2006)	1
FAM168A	0	C1orf94	1	two hybrid	Rolland T (2014)	1
ATXN1	2	TOLLIP	3	two hybrid	Lim J (2006)	1
C1orf94	1	PRR20A	0	two hybrid	Rolland T (2014)	1
RBPMS	0	ZC3H10	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
RBFOX1	1	FAM168A	0	two hybrid	Corominas R (2014)	1
DAB1	1	ROR2	0	two hybrid	Rolland T (2014)	1
DAB1	1	ZC3H10	1	two hybrid	Rolland T (2014)	1
RBPMS	0	FAM168A	0	two hybrid	Rolland T (2014)	1
FAM168A	0	PRR20A	0	two hybrid	Rolland T (2014)	1
RBFOX1	1	ATXN1	2	two hybrid, affinity chromatography technology	Lim J (2006), Lim J (2006)	2
DAB1	1	PRR20A	0	two hybrid	Rolland T (2014)	1
POGZ	49	PRR20A	0	two hybrid	Rolland T (2014)	1
RBPMS	0	ZNF488	0	two hybrid	Rolland T (2014)	1
DAB1	1	ZNF488	0	two hybrid	Rolland T (2014)	1
ATXN1	2	C1orf94	1	two hybrid, affinity chromatography technology, two hybrid	Lim J (2006), Lim J (2006), Rolland T (2014)	3
SP4	4	PRR20A	0	two hybrid	Rolland T (2014)	1
NAA38	1	PRR20A	0	two hybrid	Rolland T (2014)	1
DAB1	1	TOLLIP	3	two hybrid	Rolland T (2014)	1
DAZAP2	1	RBPMS	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
ZC3H10	1	DAZAP2	1	two hybrid	Venkatesan K (2009)	1
RBFOX1	1	PRR20A	0	two hybrid	Corominas R (2014)	1
DAZAP2	1	C1orf94	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
DAZAP2	1	FAM168A	0	two hybrid	Rolland T (2014)	1
RBFOX1	1	RBPMS	0	two hybrid, two hybrid	Corominas R (2014), Rolland T (2014)	2
ATXN1	2	DAZAP2	1	two hybrid, affinity chromatography technology	Lim J (2006), Lim J (2006)	2
SIAH1	2	TOLLIP	3	two hybrid	Rolland T (2014)	1
RBFOX1	1	C1orf94	1	two hybrid, two hybrid	Corominas R (2014), Rolland T (2014)	2
DAB1	1	POGZ	49	two hybrid	Rolland T (2014)	1
PRR20A	0	PRR20A	0	two hybrid	Rolland T (2014)	1
DAB1	1	DAZAP2	1	two hybrid	Rolland T (2014)	1
RBPMS	0	FOXP3	1	two hybrid	Rolland T (2014)	1
TOLLIP	3	PRR20A	0	two hybrid	Rolland T (2014)	1
DAB1	1	C1orf94	1	two hybrid	Rolland T (2014)	1
ROR2	0	PRR20A	0	two hybrid	Rolland T (2014)	1
PRR20A	0	SELENOV	2	two hybrid	Rolland T (2014)	1
RBPMS	0	TOLLIP	3	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
ATXN1	2	ZC3H10	1	two hybrid, two hybrid	Lim J (2006), Suter B (2013)	2
ROR2	0	RBPMS	0	two hybrid	Rolland T (2014)	1
SOX5	11	PRR20A	0	two hybrid	Rolland T (2014)	1
ZNF488	0	PRR20A	0	two hybrid	Rolland T (2014)	1
THAP1	1	PRR20A	0	two hybrid	Rolland T (2014)	1
RBPMS	0	PRR20A	0	two hybrid	Rolland T (2014)	1
RBPMS	0	POGZ	49	two hybrid	Rolland T (2014)	1
DAB1	1	SIAH1	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid	Park TJ (2003), Park TJ (2003), Park TJ (2003), Park TJ (2003), Park TJ (2003)	5
PITX1	2	RBPMS	0	two hybrid, two hybrid, two hybrid	Rual JF (2005), Corominas R (2014), Rolland T (2014)	3
ROR2	0	DAZAP2	1	affinity chromatography technology, two hybrid	Winkel A (2008), Rolland T (2014)	2
DAB1	1	FAM168A	0	two hybrid	Rolland T (2014)	1
SIAH1	2	PRR20A	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	TOLLIP	3	two hybrid, two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009), Rolland T (2014)	3
RBFOX1	1	DAZAP2	1	two hybrid	Corominas R (2014)	1
ATXN1	2	PRR20A	0	two hybrid	Rolland T (2014)	1
NCK2	2	PRR20A	0	two hybrid	Rolland T (2014)	1
PITX1	2	C1orf94	1	two hybrid	Corominas R (2014)	1
ZC3H10	1	PRR20A	0	two hybrid	Rolland T (2014)	1