Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
ADD1	rs4961	T	hydrochlorothiazide	efficacy	no		Allele T is not associated with response to hydrochlorothiazide in people with Essential hypertension as compared to allele G.	14553962	827921263
ADD1	rs4961	GG	atenolol	efficacy	no	The effect of diuretic use on risk of cardiovascular outcomes did not vary by rs4961 genotype.	Genotype GG is not associated with increased response to atenolol or verapamil in people with Hypertension as compared to genotypes GT + TT.	18657677	982033246
ADD1	rs4961	T	benazepril	efficacy	not stated	No associations were found between the interaction of ACE I/D polymorphism and this polymorphism and blood pressure response to benazepril treatment.	Allele T is not associated with response to benazepril in people with Hypertension as compared to allele G.	15773232	769170918
ADD1	rs4961	TT	bumetanide	efficacy	yes	Subjects homozygous for the T allele had increased urinary excretion of calcium as compared to GG homozygotes, during the 24 hours after drug administration.	Genotype TT is associated with increased response to bumetanide, furosemide and torasemide in healthy individuals as compared to genotype GG.	20877298	982045404