Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
CARD16	rs1503391	A	peginterferon alfa-2b	efficacy	yes	The significance of this association did not reach genome-wide significance. This genotype is associated with sustained virological response (SVR). SVR is defined as negative OCR test for Hepatitis C 6 months after the cessation of therapy. The authors do not indicate polarity of the association. However, decreased polarity can be inferred from Table 2 in the paper.	Allele A is associated with decreased response to peginterferon alfa-2b and ribavirin in people with Hepatitis C, Chronic as compared to allele C.	19749758	1444705660
CARD16	rs1792774	C	peginterferon alfa-2b	efficacy	yes	The significance of this association did not reach genome-wide significance. This genotype is associated with sustained virological response (SVR). SVR is defined as negative OCR test for Hepatitis C 6 months after the cessation of therapy. The authors do not indicate polarity of the association. However, decreased polarity can be inferred from Table 2 in the paper.	Allele C is associated with decreased response to peginterferon alfa-2b and ribavirin in people with Hepatitis C, Chronic as compared to allele T.	19749758	1444705709