Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CHRNA2 1135 METOCURINE IODIDE CHEMBL1739 antagonist TdgClinicalTrial, TEND, DrugBank, TTD 11752352, 17139284, 17016423, 6107062, 18633030
CHRNA2 1135 GALLAMINE TRIETHIODIDE CHEMBL1200993 antagonist TdgClinicalTrial, TEND, DrugBank 1337082, 17139284, 17016423
CHRNA2 1135 ATRACURIUM CHEMBL1360 TdgClinicalTrial, TEND
CHRNA2 1135 ROCURONIUM CHEMBL1201244 antagonist TdgClinicalTrial, TEND, TTD
CHRNA2 1135 VECURONIUM CHEMBL1201219 antagonist TTD
CHRNA2 1135 ATRACURIUM BESYLATE CHEMBL1200527 inhibitor DrugBank 17139284, 17016423, 19417616
CHRNA2 1135 TUBOCURARINE CHEMBL339427 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423, 11752352, 18633030, 11562442, 20338223, 19417616
CHRNA2 1135 CARBACHOL (CHEMBL14) CHEMBL14 antagonist TTD
CHRNA2 1135 GANTACURIUM CHEMBL1182997 TdgClinicalTrial
CHRNA2 1135 PROCAINE CHEMBL569 antagonist DrugBank 20045405
CHRNA2 1135 DOXACURIUM CHLORIDE CHEMBL1237099 antagonist TdgClinicalTrial, TEND, DrugBank, TTD 11752352, 17139284, 17016423, 18633030
CHRNA2 1135 DECAMETHONIUM CHEMBL1190 partial agonist, antagonist TdgClinicalTrial, TEND, DrugBank, TTD 7848904, 17139284, 17016423, 11752352, 12067008
CHRNA2 1135 METOCURINE CHEMBL1259 antagonist TdgClinicalTrial, TEND, DrugBank, TTD 11752352, 18842832, 12799358, 8132625, 18633030
CHRNA2 1135 EPIBATIDINE CHEMBL6623 agonist GuideToPharmacologyInteractions
CHRNA2 1135 CP-601927 CHEMBL3707250 agonist GuideToPharmacologyInteractions
CHRNA2 1135 HEXAMETHONIUM CHEMBL100622 channel blocker GuideToPharmacologyInteractions
CHRNA2 1135 NICOTINE CHEMBL3 TdgClinicalTrial, TEND
CHRNA2 1135 BIPERIDEN (CHEMBL1101) CHEMBL1101 TdgClinicalTrial, TEND
CHRNA2 1135 LEVALLORPHAN CHEMBL1254682 antagonist TTD
CHRNA2 1135 MECAMYLAMINE HYDROCHLORIDE CHEMBL1237082 inhibitor DrugBank 19778551, 11752352, 17139284, 17016423, 12080428
CHRNA2 1135 MIVACURIUM CHEMBL1182833 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423, 11752352, 16931985, 19352159, 19417616
CHRNA2 1135 PIPECURONIUM CHEMBL1201206 antagonist TdgClinicalTrial, TEND, DrugBank, TTD 12426786, 9227834, 17016423, 1748153, 11752352
CHRNA2 1135 CISATRACURIUM BESYLATE CHEMBL1200641 TdgClinicalTrial, TEND
CHRNA2 1135 DOXACURIUM CHEMBL1237123 TdgClinicalTrial, TEND
CHRNA2 1135 PANCURONIUM CHEMBL185073 TdgClinicalTrial, TEND

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CHRNA2 rs2472553 A bupropion efficacy no No significant effect of genotype on likelihood of being abstinent from smoking at 6 months after starting pharmacotherapy for smoking cessation. Please note that alleles have been complemented to the positive strand. Allele A is not associated with response to bupropion, nicotine or varenicline in people with Tobacco Use Disorder as compared to allele G. 29621993 1450928789
CHRNA2 rs2777511 G nicotine efficacy no Study looked at the effect of nicotine on performance in attention-related tasks. Variant referred to in the paper as rs2891398. Please note that alleles have been complemented to the positive strand. Allele G is not associated with response to nicotine in women as compared to allele A. 20231857 1450812634