Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CAPN10 11132 TACROLIMUS CHEMBL269732 PharmGKB

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CAPN10 rs3792269 G metformin efficacy yes Treatment success was defined as 1) achieving HbA1c <7 % and 2) absolute reduction in HbAlc after 6-months of metformin therapy. The relationships between genotypes and outcomes were evaluated using multivariate logistic and linear models. Allele G is associated with decreased response to metformin in people with Diabetes Mellitus as compared to allele A. 25327507 1296666368