PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
COPS3	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Min KW (2005), Enchev RI (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	9
COPS5	0	TYK2	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Muromoto R (2013), Muromoto R (2013), Muromoto R (2013)	3
DTL	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Higa LA (2006), Higa LA (2006), Sertic S (2013), Shibata E (2014), Hein MY (2015), Shibata E (2011), Higa LA (2006), Higa LA (2006)	9
FBXO7	1	COPS3	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL3	17	CUL1	7	affinity chromatography technology, affinity chromatography technology, biochemical	Bennett EJ (2010), Bennett EJ (2010), Wan C (2015)	3
YWHAZ	1	APP	1	pull down	Olah J (2011)	1
HIF1A	1	NCOA1	6	pull down	Carrero P (2000)	1
COPS5	0	FBXO22	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
CUL3	17	YWHAZ	1	affinity chromatography technology	Bennett EJ (2010)	1
JUN	0	SMAD4	9	affinity chromatography technology	Li X (2015)	1
TP53	0	COPS4	0	affinity chromatography technology	Bhansali M (2014)	1
COPS8	2	COPS7A	0	biochemical, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Huang X (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
COPS5	0	HNRNPL	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Fei T (2017)	2
FBXO7	1	COPS7B	0	affinity chromatography technology	Huttlin EL (2017)	1
JUN	0	APP	1	pull down	Miyamoto-Sato E (2010)	1
SMAD7	1	CTNNB1	30	affinity chromatography technology, imaging technique, affinity chromatography technology	Edlund S (2005), Edlund S (2005), Tang Y (2008)	3
CUL2	3	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015)	3
DDA1	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Jin J (2006), Hein MY (2015)	3
GFER	1	COPS2	5	affinity chromatography technology	Wang Y (2004)	1
CUL5	1	UPF1	8	affinity chromatography technology	Bennett EJ (2010)	1
HNRNPL	3	APP	1	affinity chromatography technology	Fei T (2017)	1
DCAF1	5	CUL4A	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ahn J (2010), Belzile JP (2007), He YJ (2006), McCall CM (2008), McCall CM (2008), McCall CM (2008), McCall CM (2008), Hrecka K (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Kyei GB (2015)	14
UCHL1	1	COPS5	0	two hybrid, affinity chromatography technology	Caballero OL (2002), Caballero OL (2002)	2
DDB1	6	COPS6	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009)	5
COPS5	0	NCOA1	6	two hybrid, pull down	Chauchereau A (2000), Chauchereau A (2000)	2
COPS4	0	HUS1	1	genetic interference	Horlbeck MA (2018)	1
HIF1A	1	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chew EH (2007), Sufan RI (2006), Luo W (2010), Heir P (2013), Russell RC (2008)	5
CUL4A	2	CRBN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Ito T (2010), Bennett EJ (2010), Liu Y (2015), Liu Y (2015), Diaz-Rodriguez E (2016), Xu Q (2016), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Eichner R (2016), Eichner R (2016), Huttlin EL (2017), Kroenke J (2014)	14
MDM2	2	ERCC8	1	affinity chromatography technology	Latini P (2011)	1
GPS1	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, two hybrid, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Stotland A (2012), Huang X (2005), Sharon M (2009), Kapelari B (2000), Tsuge T (2001), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
COPS2	5	DCAF4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL1	7	COPS9	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Ebina M (2013)	2
YWHAZ	1	HNRNPL	3	affinity chromatography technology	Ewing RM (2007)	1
TP53	0	RANBP9	5	two hybrid	Chen J (2008)	1
COPS6	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Birol M (2014)	5
CAND1	2	HNRNPL	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Fei T (2017)	2
TXN	1	NFKB1	2	x-ray crystallography	Qin J (1995)	1
COPS8	2	DCAF4	3	affinity chromatography technology	Huttlin EL (2017)	1
CUL4A	2	MDM2	2	affinity chromatography technology, affinity chromatography technology	Banks D (2006), Latini P (2011)	2
COPS6	0	FBXO7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2017)	3
DDB1	6	AHR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kawajiri K (2009), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	4
CTNNB1	30	YWHAZ	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen CH (2012), Chen CH (2012), Tian Q (2004), Tian Q (2004), Tian Q (2004), Fang D (2007)	6
COPS3	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
COPS5	0	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	11
COPS7A	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015), Huttlin EL (2017)	3
DDB1	6	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006)	2
TP53	0	TOR1AIP2	2	affinity chromatography technology	Fogeron ML (2013)	1
RAD9A	1	COPS5	0	imaging technique, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Huang J (2007), Huang J (2007), Huang J (2007), Huang J (2007), Huang J (2007)	5
COPS4	0	COPS7B	0	affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	7
COPS4	0	CRBN	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kroenke J (2014)	2
NEDD8	0	KLHL15	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL2	3	YWHAZ	1	affinity chromatography technology	Bennett EJ (2010)	1
RFWD2	0	JUN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Bianchi E (2003), Yi C (2005), Lu G (2014), Li X (2015), Huttlin EL (2017), Zou S (2016)	7
MDM2	2	PDLIM7	0	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010)	4
COPS6	0	FBXO22	1	affinity chromatography technology	Sowa ME (2009)	1
CDK2	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Youn CK (2005), Porter LA (2003), Law BK (2002), Connor MK (2003), Naderi S (2005), Varshochi R (2005), Hsu SP (2008), McAndrew CW (2007), Peiretti A (2003), Peiretti A (2003), Haddad MM (1999), Xu X (1999), Xu X (1999), Radu M (2008), Mori S (1999), Schulman BA (1998), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Sheaff RJ (1997), Vlach J (1996), Vlach J (1996), Vlach J (1997), Liu S (2009), Rosner M (2004), Ciarallo S (2002), Ciarallo S (2002), Wang Y (2008), Bockstaele L (2006), Chu I (2007), Chu I (2007), Levkau B (1998), Levkau B (1998), Lacy ER (2005), Zhao J (1998), Seo DW (2006), Kossatz U (2006), Grimmler M (2007), Grimmler M (2007), Varjosalo M (2013), Varjosalo M (2013), Montagnoli A (1999), So J (2015), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Lovisa S (2016), Qiu H (2016), Carrasco-Garcia E (2011), Huttlin EL (2017), Hu B (2017)	52
ERCC8	1	VCP	6	affinity chromatography technology	He J (2016)	1
DDB1	6	UCHL1	1	affinity chromatography technology, affinity chromatography technology	Hussain S (2013), Hussain S (2013)	2
CUL5	1	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017), Zhu Z (2017)	3
NRBP1	3	COPS5	0	two hybrid, affinity chromatography technology	Wang H (2006), Wang H (2006)	2
CUL4B	8	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Jin J (2006), Wang H (2006), Higa LA (2006), Higa LA (2006), Kawajiri K (2009), Bennett EJ (2010), Havugimana PC (2012), Ji Q (2014), Wan C (2015), Hein MY (2015), Mo Y (2017), Mo Y (2017), Yang Y (2015), Yang Y (2015), Yang Y (2015), Higa LA (2006), Higa LA (2006), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	23
CUL4A	2	TP53	0	affinity chromatography technology	Banks D (2006)	1
COPS7A	0	DCAF4	3	affinity chromatography technology	Hein MY (2015)	1
HUS1	1	COPS5	0	imaging technique, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, genetic interference	Huang J (2007), Huang J (2007), Huang J (2007), Huang J (2007), Huang J (2007), Horlbeck MA (2018)	6
IKBKB	1	COPS5	0	two hybrid, affinity chromatography technology, fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, affinity chromatography technology	Orel L (2010), Orel L (2010), Orel L (2010), Orel L (2010), Asare Y (2013), Asare Y (2013)	6
COPS6	0	KCTD10	1	affinity chromatography technology	Bennett EJ (2010)	1
DDB1	6	COPS2	5	affinity chromatography technology, affinity chromatography technology, pull down	Angers S (2006), Jin J (2006), Emberley ED (2012)	3
PPP1CC	2	APP	1	pull down	Olah J (2011)	1
CUL5	1	COPS5	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
GUCY1A3	0	TP53	0	affinity chromatography technology, affinity chromatography technology	Bhansali M (2014), Bhansali M (2014)	2
F2RL1	1	COPS5	0	two hybrid, pull down, affinity chromatography technology	Luo W (2006), Luo W (2006), Luo W (2006)	3
COPS7A	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Bennett EJ (2010), Huang X (2016), Reitsma JM (2017)	4
HIF1A	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang KL (2014), Zhang KL (2014), Xi Y (2013)	3
PPP1CC	2	VCP	6	affinity chromatography technology, affinity chromatography technology	Cid C (2007), Cid C (2007)	2
CENPT	0	APP	1	pull down	Olah J (2011)	1
CUL5	1	COPS4	0	affinity chromatography technology	Bennett EJ (2010)	1
BCL3	2	JUN	0	two hybrid, pull down, affinity chromatography technology	Na SY (1999), Na SY (1999), Na SY (1999)	3
ERN1	1	UCHL1	1	affinity chromatography technology	Zhu X (2014)	1
FBXW4	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Busino L (2003), Lockwood WW (2013), Chung FZ (2014), Low TY (2014), Reitsma JM (2017)	5
CUL3	17	UPF1	8	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
TP53BP1	3	COPS5	0	two hybrid, affinity chromatography technology	Kwak HJ (2005), Kwak HJ (2005)	2
CRBN	2	COPS7B	0	affinity chromatography technology	Kroenke J (2014)	1
SKP2	2	CUL5	1	affinity chromatography technology, affinity chromatography technology	Nie L (2011), Bennett EJ (2010)	2
DCAF11	2	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	3
COPS5	0	COPS5	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Bennett EJ (2010), Echalier A (2013), Echalier A (2013), DenBoer LM (2013)	4
CDK2	0	YWHAZ	1	affinity chromatography technology	Neganova I (2011)	1
COPS5	0	LRRC14	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
CUL4B	8	NFKB1	2	affinity chromatography technology	Bennett EJ (2010)	1
FBXL5	3	COPS3	1	affinity chromatography technology	Huttlin EL (2017)	1
GPS1	1	TP53	0	biochemical	Bech-Otschir D (2001)	1
CUL5	1	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	ERCC8	1	affinity chromatography technology	Bennett EJ (2010)	1
FBXL5	3	COPS2	5	affinity chromatography technology	Huttlin EL (2017)	1
NEDD8	0	COPS2	5	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
VCP	6	CDKN1B	1	affinity chromatography technology	Yu CC (2013)	1
NUPR1	0	COPS5	0	pull down, affinity chromatography technology	Malicet C (2006), Malicet C (2006)	2
COPS6	0	NFKB1	2	affinity chromatography technology	Bennett EJ (2010)	1
ERCC8	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Olma MH (2009)	3
ITGB2	4	YWHAZ	1	affinity chromatography technology, affinity chromatography technology	Fagerholm S (2002), Fagerholm S (2002)	2
CUL5	1	KLHL18	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	CUL3	17	affinity chromatography technology	Bennett EJ (2010)	1
COPS3	1	COPS7B	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Enchev RI (2010), Olma MH (2009), Havugimana PC (2012), Huttlin EL (2015), Huang X (2016), Huttlin EL (2017)	6
IKBKB	1	CUL1	7	affinity chromatography technology	Orel L (2010)	1
COPS6	0	CDK2	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	DDB1	6	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Bennett EJ (2010), Sertic S (2013), Rossi M (2013), Jin J (2006), Shibata E (2011), Higa LA (2006)	7
COPS6	0	COPS9	1	affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Bennett EJ (2010), Rozen S (2015)	3
RFWD2	0	DDB2	1	affinity chromatography technology	Olma MH (2009)	1
CUL4B	8	XRN2	1	affinity chromatography technology	Bennett EJ (2010)	1
IKBKB	1	JUN	0	enzymatic study	Orel L (2010)	1
COPS5	0	BTBD2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
CHUK	5	COPS3	1	affinity chromatography technology	Asare Y (2013)	1
GPS1	1	CARD11	4	affinity chromatography technology	Welteke V (2009)	1
CCNDBP1	0	JUN	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL3	17	KLHL9	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Maerki S (2009), Sumara I (2007), Sumara I (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Maerki S (2009)	7
COPS2	5	XRN2	1	genetic interference	Horlbeck MA (2018)	1
LRR1	1	COPS7B	0	affinity chromatography technology	Olma MH (2009)	1
PPP1CC	2	CDK2	0	affinity chromatography technology	Flores-Delgado G (2007)	1
COPS2	5	COPS4	0	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Huang X (2005), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	8
DTL	0	COPS2	5	affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Higa LA (2006)	2
DDB1	6	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Angers S (2006), Jin J (2006), Min KW (2005), Emberley ED (2012), Olma MH (2009)	5
APP	1	TPD52L2	0	two hybrid	Wang J (2011)	1
COPS3	1	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	5
COPS5	0	XRN2	1	affinity chromatography technology, genetic interference	Bennett EJ (2010), Horlbeck MA (2018)	2
ITGB2	4	RACK1	2	two hybrid, pull down, affinity chromatography technology	Liliental J (1998), Liliental J (1998), Liliental J (1998)	3
KLHL22	3	GFER	1	affinity chromatography technology	Huttlin EL (2017)	1
COPS6	0	COPS4	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	14
FBXW4	0	COPS7B	0	affinity chromatography technology	Lockwood WW (2013)	1
SKP2	2	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Wang W (2003), Sitry D (2002), Fujita N (2002), Ji P (2006), Zancai P (2005), Ji P (2004), Iovine B (2011), Calvisi DF (2009), Spruck C (2001), Bashir T (2010), Bashir T (2010), Li P (2004), Boutonnet C (2010), Rosner M (2004), Rosner M (2004), Carrano AC (1999), Carrano AC (1999), Carrano AC (1999), Wu J (2012), Strohmaier H (2001), Rodier G (2008), Rodier G (2008), Ooi LC (2013), Yumimoto K (2013), Ooi LC (2013), Cen B (2010), Enchev RI (2012), Yumimoto K (2012), Shi P (2011), Lovisa S (2016), Cen B (2009), Chan CH (2013), Ma X (2017)	33
COPS5	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Bennett EJ (2010), Oh W (2006), Chun Y (2013), Chun Y (2013), Chun Y (2013), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
CUL3	17	NFKB1	2	affinity chromatography technology	Bennett EJ (2010)	1
PGR	1	CDK2	0	affinity chromatography technology, two hybrid, affinity chromatography technology	Narayanan R (2005), Narayanan R (2005), Vicent GP (2011)	3
COPS5	0	TOR1AIP2	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
DDA1	1	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	4
COPS6	0	KLHL13	0	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
COPS6	0	KLHL9	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
RFWD2	0	YWHAZ	1	imaging technique, affinity chromatography technology, pull down, affinity chromatography technology	Su CH (2010), Su CH (2010), Su CH (2010), Su CH (2010)	4
COPS9	1	COPS8	2	affinity chromatography technology, biochemical	Rozen S (2015), Rozen S (2015)	2
FBXW4	0	COPS2	5	affinity chromatography technology, affinity chromatography technology	Lockwood WW (2013), Lockwood WW (2013)	2
CUL3	17	KLHL13	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Maerki S (2009), Sumara I (2007), Sumara I (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Maerki S (2009)	7
CUL4B	8	COPS8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	4
COPS5	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Min KW (2005), Chua YS (2011), Boh BK (2011), Emberley ED (2012), Emberley ED (2012), Choo YY (2011), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Enchev RI (2012), Birol M (2014), Pick E (2012), Sharon M (2009), Enchev RI (2012), Bornstein G (2015), Rockel B (2014), Schlierf A (2016), Reitsma JM (2017), Reitsma JM (2017)	23
CHUK	5	CARD11	4	affinity chromatography technology, imaging technique	McCully RR (2008), Sommer K (2005)	2
CUL4A	2	CUL5	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
COPS5	0	CAND1	2	biochemical, affinity chromatography technology	Bornstein G (2006), Bennett EJ (2010)	2
YWHAZ	1	CDKN1B	1	pull down	Sekimoto T (2004)	1
TP53	0	HNRNPL	3	affinity chromatography technology	Horikawa I (2014)	1
GFER	1	HUS1	1	genetic interference	Horlbeck MA (2018)	1
COPS8	2	COPS3	1	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Min KW (2005), Enchev RI (2010), Sharon M (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
IKBKB	1	COPS4	0	two hybrid, affinity chromatography technology	Orel L (2010), Orel L (2010)	2
CDK2	0	UPF1	8	affinity chromatography technology	Neganova I (2011)	1
COPS8	2	COPS2	5	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Yang X (2002), Huang X (2005), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	9
FBXO7	1	RACK1	2	affinity chromatography technology	Teixeira FR (2016)	1
CUL4A	2	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Pick E (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006)	7
GPS1	1	SKP2	2	affinity chromatography technology	Lyapina S (2001)	1
NEDD8	0	COPS8	2	affinity chromatography technology	Bennett EJ (2010)	1
AHR	3	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Ohtake F (2007), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	5
COPS5	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), McCall CM (2008), Bennett EJ (2010), Olma MH (2009)	4
ERCC8	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down	Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Fei J (2012), Jin J (2006), He J (2016), Groisman R (2006), Groisman R (2006)	8
COPS4	0	FBXO17	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	3
SMAD4	9	SMAD5	2	affinity chromatography technology, two hybrid, two hybrid	Hanai J (1999), Haag J (2006), Colland F (2004)	3
TRAF2	1	ERN1	1	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Kaneko M (2003), Zhu X (2014), Chen TC (2014), Zeng T (2015)	4
EDNRA	1	COPS5	0	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Nishimoto A (2010), Nishimoto A (2010), Nishimoto A (2010), Nishimoto A (2010)	4
DDB1	6	DCAF11	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Angers S (2006), Jin J (2006), He YJ (2006), Olma MH (2009), Jin J (2006), Huttlin EL (2017), Lo JY (2017)	8
COPS4	0	TOR1AIP2	2	affinity chromatography technology	Olma MH (2009)	1
COPS2	5	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Huang X (2005), Bennett EJ (2010), Olma MH (2009), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	6
COPS6	0	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
COPS6	0	TOR1AIP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
CRBN	2	HNRNPL	3	affinity chromatography technology	Nguyen TV (2016)	1
TOP2A	2	COPS5	0	affinity chromatography technology, two hybrid, pull down	Chen MC (2011), Yun J (2004), Yun J (2004)	3
COPS5	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Sertic S (2013), Higa LA (2006), Higa LA (2006)	5
RFWD2	0	COPS7B	0	affinity chromatography technology	Olma MH (2009)	1
CUL5	1	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Angers S (2006), Hu J (2004), Chua YS (2011), Tron AE (2012), Zheng J (2002), He YJ (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Gastaldello S (2012), Liu J (2002), Liu J (2002), Olma MH (2009), Olma MH (2009), Yang Y (2016), Yang Y (2016)	18
CUL4A	2	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Kapetanaki MG (2006), Matsuda N (2005), Higa LA (2006), Nag A (2001), Takedachi A (2010), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), Groisman R (2003), Groisman R (2003), Hrecka K (2007), Shiyanov P (1999), Shiyanov P (1999), Bennett EJ (2010), Kulaksiz G (2005), Kulaksiz G (2005), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Groisman R (2003), Huttlin EL (2015), Hein MY (2015), Groisman R (2006), Yang Y (2016), Huttlin EL (2017), Fantini D (2017)	31
GFER	1	XRN2	1	genetic interference	Horlbeck MA (2018)	1
COPS4	0	KCTD10	1	genetic interference	Horlbeck MA (2018)	1
COPS7A	0	PTGS2	0	affinity chromatography technology, pull down	Neuss H (2007), Neuss H (2007)	2
CUL1	7	RACK1	2	affinity chromatography technology	Bennett EJ (2010)	1
GFER	1	COPS5	0	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Lu C (2002), Lu C (2002), Lu C (2002), Chen X (2003), Chen X (2003), Wang Y (2004)	6
COPS3	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Yang X (2002), Enchev RI (2010), Huang X (2005), Kapelari B (2000), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Rozen S (2015), Huttlin EL (2017)	13
CRBN	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu Q (2016), Eichner R (2016), Huttlin EL (2017), Kroenke J (2014)	4
NEDD8	0	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	TOR1AIP2	2	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	KLHL22	3	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
COPS4	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Shibata E (2011), Higa LA (2006)	3
CUL3	17	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010), Schenkova K (2012)	3
FBXO17	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Glenn KA (2008), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017), Reitsma JM (2017)	5
COPS4	0	XRN2	1	genetic interference	Horlbeck MA (2018)	1
DDB1	6	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Angers S (2006), Behrends C (2010), Pick E (2007), Pick E (2007), Hrecka K (2007), Hrecka K (2007), Olma MH (2009), Olma MH (2009), Jin J (2006), Wan C (2015)	10
COPS6	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Reitsma JM (2017)	7
SMAD7	1	TP53	0	affinity chromatography technology	Zhang S (2006)	1
CUL4A	2	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Rao F (2014), Rao F (2014), Huttlin EL (2015), Cavadini S (2016), Scherer PC (2016), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	13
CDKN1B	1	TRAF2	1	two hybrid, imaging technique	Rual JF (2005), Chen TC (2014)	2
TP53	0	CHUK	5	affinity chromatography technology	Huang WC (2007)	1
CRBN	2	COPS7A	0	affinity chromatography technology	Kroenke J (2014)	1
CUL5	1	TPD52L2	0	biochemical	Kristensen AR (2012)	1
PGR	1	NCOA1	6	two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid	Chauchereau A (2003), Amazit L (2011), Amazit L (2011), Amazit L (2011), An BS (2006), Chauchereau A (2000)	6
COPS5	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Rao F (2014), Pick E (2012), Groisman R (2003), Groisman R (2003), Huttlin EL (2015), Cavadini S (2016), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	19
CUL4A	2	COPS9	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL1	7	HNRNPL	3	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	MDM2	2	affinity chromatography technology, pull down	Zhang XC (2008), Zhang XC (2008)	2
RAD9A	1	RAD1	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dufault VM (2003), Dufault VM (2003), Volkmer E (1999), Volkmer E (1999), Griffith JD (2002), Hirai I (2002), Hirai I (2002), Lindsey-Boltz LA (2001), Huttlin EL (2015), Huttlin EL (2017)	10
RANBP9	5	COPS5	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Wang H (2013), Wang H (2013), Wang H (2013)	3
APP	1	UCHL1	1	affinity chromatography technology	Zhang M (2014)	1
NEDD8	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
TP53	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology	Latini P (2011), Latini P (2011)	2
DCAF4	3	COPS7B	0	affinity chromatography technology	Huttlin EL (2017)	1
CARD11	4	COPS5	0	affinity chromatography technology, affinity chromatography technology	Welteke V (2009), Welteke V (2009)	2
YWHAZ	1	COPS5	0	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Bennett EJ (2010)	2
MDM2	2	CUL4B	8	affinity chromatography technology	Latini P (2011)	1
CUL3	17	VCP	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Besten Wd (2012)	2
RFWD2	0	BTBD2	4	affinity chromatography technology	Olma MH (2009)	1
RFWD2	0	DCAF11	2	affinity chromatography technology	Olma MH (2009)	1
MDM2	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Latini P (2011), Jacob AG (2014)	2
MIF	1	COPS5	0	affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Kleemann R (2000), Kleemann R (2000), Burger-Kentischer A (2005), Burger-Kentischer A (2005), Burger-Kentischer A (2005), Burger-Kentischer A (2005)	6
COPS5	0	UPF1	8	affinity chromatography technology, biochemical	Bennett EJ (2010), Wan C (2015)	2
DDA1	1	COPS2	5	affinity chromatography technology	Olma MH (2009)	1
CUL2	3	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
FBXW4	0	COPS3	1	affinity chromatography technology	Lockwood WW (2013)	1
COPS6	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Higa LA (2006)	4
RFWD2	0	CDKN1B	1	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Choi HH (2015), Choi HH (2015), Choi HH (2015), Choi HH (2015), Choi HH (2015)	5
DTL	0	YWHAZ	1	affinity chromatography technology, affinity chromatography technology	Dar A (2014), Dar A (2014)	2
COPS8	2	BTBD2	4	affinity chromatography technology	Huttlin EL (2017)	1
COPS7B	0	APP	1	pull down	Olah J (2011)	1
DTL	0	GPS1	1	affinity chromatography technology	Higa LA (2006)	1
UCHL1	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu J (2008), Li L (2010), Ilic A (2017), Ilic A (2017)	4
VCP	6	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Yu CC (2013), Fogeron ML (2013)	3
COPS7A	0	BTBD2	4	affinity chromatography technology	Hein MY (2015)	1
FBXO7	1	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL4A	2	SKP2	2	affinity chromatography technology	Bondar T (2006)	1
HNRNPL	3	FNIP1	2	affinity chromatography technology	Fei T (2017)	1
COPS5	0	CDKN1B	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Caballero OL (2002), Kouvaraki MA (2006), Kouvaraki MA (2006), Kouvaraki MA (2006), Hsieh YH (2007), Hwang CY (2004), Hwang CY (2004), Pan Y (2012), Wang Y (2008), Wang Y (2008), Yamaguchi F (2008), Wang Y (2014), Zhang H (2017), Zhang H (2017)	14
CUL2	3	GPS1	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina S (2001)	2
CUL5	1	DDB1	6	affinity chromatography technology	Bennett EJ (2010)	1
CUL1	7	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Min KW (2005), Lee JE (2011), Bennett EJ (2010), Lyapina S (2001), Reitsma JM (2017)	6
CUL3	17	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huang X (2016), Huttlin EL (2017)	3
RFWD2	0	CUL2	3	affinity chromatography technology	Olma MH (2009)	1
CREB3	1	COPS5	0	pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	DenBoer LM (2013), DenBoer LM (2013), DenBoer LM (2013), DenBoer LM (2013), DenBoer LM (2013), DenBoer LM (2013)	6
JUN	0	TOP2A	2	far western blotting	Kroll DJ (1993)	1
CUL4A	2	COPS8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2017), Boldt K (2016)	7
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
COPS2	5	FBXO7	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL3	17	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina S (2001), Huttlin EL (2017)	3
CTNNB1	30	COPS3	1	affinity chromatography technology	Huang X (2009)	1
CUL4B	8	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Jin J (2006), Hein MY (2015), Wang X (2017)	4
JUN	0	HIF1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alfranca A (2002), Yu B (2009), Yu B (2009)	3
NEDD8	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
CDK2	0	CUL4B	8	affinity chromatography technology	Neganova I (2011)	1
CDK2	0	MIF	1	affinity chromatography technology	Neganova I (2011)	1
HIF1A	1	RACK1	2	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Baek JH (2007), Liu YV (2007), Liu YV (2007), Liu YV (2007), Sun H (2013), Amir S (2009), Kuo YC (2015), Lee SH (2015)	8
CUL5	1	KLHL15	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	BTBD2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sumara I (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Maerki S (2009)	5
CRBN	2	VCP	6	affinity chromatography technology	Nguyen TV (2016)	1
COPS5	0	LRR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
COPS6	0	KLHL18	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
FBXW4	0	COPS7A	0	affinity chromatography technology	Lockwood WW (2013)	1
CRBN	2	TXN	1	affinity chromatography technology	Nguyen TV (2016)	1
TP53	0	DDB1	6	affinity chromatography technology	Fogeron ML (2013)	1
CUL1	7	COPS8	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Menon S (2008), Bennett EJ (2010), Enchev RI (2012), Reitsma JM (2017)	4
COPS3	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Reitsma JM (2017)	4
COPS6	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	6
COPS5	0	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Bhansali M (2014), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	13
COPS5	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Groisman R (2006)	5
COPS5	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	8
CUL3	17	CUL2	3	biochemical	Wan C (2015)	1
CUL1	7	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina SA (1998), Huttlin EL (2015), Huttlin EL (2017)	4
COPS4	0	BTBD2	4	affinity chromatography technology	Olma MH (2009)	1
COPS7B	0	BTBD1	2	affinity chromatography technology	Huttlin EL (2017)	1
HUS1	1	XRN2	1	genetic interference	Horlbeck MA (2018)	1
FBXW4	0	COPS6	0	affinity chromatography technology	Lockwood WW (2013)	1
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
SMAD4	9	SMAD7	1	genetic interference, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Lebrun JJ (1999), Moren A (2005), Moren A (2005), Moren A (2005), Zhang S (2007), Yan X (2016)	6
KLHL13	0	COPS2	5	affinity chromatography technology	Sowa ME (2009)	1
COPS6	0	CRBN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Olma MH (2009), Kroenke J (2014)	3
COPS6	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
PPP1CC	2	NRBP1	3	two hybrid	Fardilha M (2011)	1
SKP2	2	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Yam CH (1999), Calvisi DF (2009), Gao D (2009), Bashir T (2010), Yao ZP (2006), Rosner M (2009), Lyapina SA (1998), Zhang H (1995), Zhang H (1995), Inuzuka H (2012), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	17
GUCY1A3	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Bhansali M (2014), Bhansali M (2014)	2
COPS2	5	COPS7B	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	7
COPS6	0	KLHL24	1	affinity chromatography technology	Sowa ME (2009)	1
DDB1	6	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Olma MH (2009)	3
HNRNPL	3	CUL4A	2	affinity chromatography technology	Fei T (2017)	1
COPS8	2	GPS1	1	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Stotland A (2012), Sharon M (2009), Sun Y (2002), Kristensen AR (2012), Lingaraju GM (2014), Lyapina S (2001), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	10
CPNE3	2	COPS5	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Choi HY (2016), Choi HY (2016), Choi HY (2016)	3
COPS5	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
CUL4B	8	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015), Hein MY (2015)	4
NFKB1	2	TP53BP1	3	affinity chromatography technology	Wen Y (2000)	1
CUL3	17	XRN2	1	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	ZEB1	3	affinity chromatography technology, imaging technique	Zhang S (2017), Zhang S (2017)	2
VCP	6	APP	1	affinity chromatography technology	Jang JK (2017)	1
COPS5	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	4
CDK2	0	VCP	6	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Fogeron ML (2013)	2
DDB1	6	TOR1AIP2	2	affinity chromatography technology	Angers S (2006)	1
FBXO11	14	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abida WM (2007), Duan S (2011), Bennett EJ (2010), Jeong YT (2013), Reitsma JM (2017), Reitsma JM (2017)	6
RFWD2	0	COPS2	5	biochemical, affinity chromatography technology	Yi C (2002), Olma MH (2009)	2
CUL4B	8	CUL5	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
COPS5	0	CDK2	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Chun Y (2013)	2
HNRNPL	3	TYK2	1	affinity chromatography technology	Fei T (2017)	1
TRAF2	1	FBXO7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kuiken HJ (2012), Chen CM (2014), Huttlin EL (2017)	3
DDA1	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pick E (2007), Olma MH (2009), Olma MH (2009)	3
JUN	0	RACK1	2	affinity chromatography technology	Zhang J (2011)	1
PDLIM7	0	TRAF2	1	protein complementation assay, protein complementation assay	Talaty P (2011), Talaty P (2011)	2
FBXW4	0	COPS5	0	affinity chromatography technology, affinity chromatography technology	Lockwood WW (2013), Lockwood WW (2013)	2
PTGS2	0	COPS5	0	biochemical, affinity chromatography technology, pull down	Neuss H (2007), Neuss H (2007), Neuss H (2007)	3
AHR	3	COPS5	0	affinity chromatography technology, affinity chromatography technology	Lee CC (2016), Lee CC (2016)	2
DDB2	1	DDB1	6	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bergametti F (2002), Martinez E (2001), Guerrero-Santoro J (2008), Angers S (2006), Wang H (2006), Kapetanaki MG (2006), Kapetanaki MG (2006), Higa LA (2006), Takedachi A (2010), Fischer ES (2011), Scrima A (2008), Groisman R (2003), Groisman R (2003), Schroefelbauer B (2007), Kulaksiz G (2005), Inoki T (2004), Bontron S (2002), Rapic-Otrin V (2003), Olma MH (2009), Liu W (2000), Jin J (2006), Huttlin EL (2015), Zhao R (2014), Xie X (2015), Groisman R (2006), Yang Y (2016), Huttlin EL (2017), Chitale S (2017), Fantini D (2017), Fantini D (2017), Ohtake F (2007)	31
DTL	0	MDM2	2	affinity chromatography technology	Banks D (2006)	1
NFKB1	2	CTNNB1	30	imaging technique, affinity chromatography technology, imaging technique	Kim JH (2005), Kim JH (2005), Chen TC (2014)	3
CUL4B	8	TXN	1	affinity chromatography technology	Bennett EJ (2010)	1
BTBD2	4	COPS6	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stelzl U (2005), Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	5
CDKN1B	1	UCHL1	1	affinity chromatography technology	Caballero OL (2002)	1
NEDD8	0	YWHAZ	1	affinity chromatography technology	Bennett EJ (2010)	1
DCAF1	5	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Olma MH (2009), Hein MY (2015)	3
RFWD2	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
CUL2	3	CUL4B	8	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	LRR1	1	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Christmann M (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Scherer PC (2016), Huttlin EL (2017), Boldt K (2016)	15
RACK1	2	FBXO17	1	affinity chromatography technology	Peng D (2017)	1
IKBKB	1	HIF1A	1	affinity chromatography technology	Nowicka AM (2016)	1
COPS6	0	CDKN1B	1	affinity chromatography technology	Choi HH (2015)	1
COPS2	5	TP53	0	affinity chromatography technology	Huang X (2005)	1
COPS7B	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
CUL1	7	YWHAZ	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	VCP	6	affinity chromatography technology	Besten Wd (2012)	1
CTNNB1	30	TOP2A	2	affinity chromatography technology, affinity chromatography technology	Sato S (2005), Sato S (2005)	2
COPS5	0	VCP	6	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology	Cayli S (2009), Cayli S (2009), Cayli S (2009), Cayli S (2009), Bennett EJ (2010)	5
DCAF11	2	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL1	7	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Inuzuka H (2010), Inuzuka H (2010), He Y (2014)	3
COPS4	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2017)	2
TP53	0	NCOA1	6	two hybrid, pull down	Lee SK (1999), Lee SK (1999)	2
CAND1	2	XRN2	1	affinity chromatography technology	Bennett EJ (2010)	1
FBXO7	1	NEDD8	0	affinity chromatography technology	Teixeira FR (2016)	1
CUL5	1	CUL1	7	affinity chromatography technology	Bennett EJ (2010)	1
CTNNB1	30	COPS5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang X (2009), Jumpertz S (2014), Jumpertz S (2014)	3
CUL2	3	COPS8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017), Boldt K (2016)	3
PDLIM7	0	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down	Jung CR (2010), Jung CR (2010), Jung CR (2010)	3
CUL4A	2	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Min KW (2005), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	10
HTR6	3	COPS5	0	pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Yun HM (2010), Yun HM (2010), Yun HM (2010), Yun HM (2010)	4
COPS3	1	FBXO17	1	affinity chromatography technology	Olma MH (2009)	1
RFWD2	0	ERCC8	1	affinity chromatography technology	Olma MH (2009)	1
COPS3	1	DTL	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Higa LA (2006)	2
RFWD2	0	CUL1	7	affinity chromatography technology	Olma MH (2009)	1
DCAF1	5	COPS8	2	affinity chromatography technology, affinity chromatography technology	Hrecka K (2007), Huttlin EL (2017)	2
CUL4A	2	TOR1AIP2	2	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010)	2
MDM2	2	JUN	0	pull down	Miyamoto-Sato E (2010)	1
SMAD4	9	NFKB1	2	affinity chromatography technology	Li X (2015)	1
CUL3	17	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huang X (2016), Huttlin EL (2017)	5
RAD1	0	COPS5	0	imaging technique, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Huang J (2007), Huang J (2007), Huang J (2007), Huang J (2007), Huang J (2007)	5
COPS5	0	CENPW	1	affinity chromatography technology, affinity chromatography technology, biochemical	Chun Y (2013), Chun Y (2013), Chun Y (2013)	3
COPS2	5	BTBD1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS3	1	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, two hybrid, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Min KW (2005), Enchev RI (2010), Stotland A (2012), Sharon M (2009), Kapelari B (2000), Tsuge T (2001), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	12
CUL4B	8	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
CUL4A	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Angers S (2006), Jin J (2006), Wang H (2006), Kapetanaki MG (2006), Matsuda N (2005), Hu J (2004), Hu J (2004), Hu J (2004), Ahn J (2010), Maddika S (2009), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), He YJ (2006), McCall CM (2008), McCall CM (2008), Shiyanov P (1999), Bennett EJ (2010), Gastaldello S (2012), Kanei-Ishii C (2012), Hodgson AJ (2012), Kulaksiz G (2005), Wu Z (2012), Wu Z (2012), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Rao F (2014), Wan C (2015), Liu Y (2015), Zha Z (2015), Mouysset J (2015), Gao J (2015), Yang Y (2016), Yang Y (2016), Scherer PC (2016), Eichner R (2016), Mo Y (2017), Mo Y (2017), Peng Z (2016), Higa LA (2006), Ohtake F (2007)	46
COPS7A	0	COPS2	5	affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
MAP2K2	2	CCNDBP1	0	two hybrid	Rolland T (2014)	1
LRR1	1	COPS8	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2017)	2
CTNNB1	30	CDK2	0	pull down, affinity chromatography technology	Park CS (2004), Park CS (2004)	2
BCL2L14	2	COPS5	0	two hybrid, affinity chromatography technology, pull down	Liu X (2008), Liu X (2008), Liu X (2008)	3
RFWD2	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
HNRNPL	3	MAP2K2	2	affinity chromatography technology	Fei T (2017)	1
NEDD8	0	COPS3	1	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
OPRM1	0	COPS5	0	two hybrid, pull down, pull down, affinity chromatography technology	Petko J (2013), Petko J (2013), Petko J (2013), Petko J (2013)	4
CUL1	7	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Min KW (2005), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Reitsma JM (2017)	6
COPS5	0	KLHL18	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
CUL4A	2	NFKB1	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009)	7
FBXO17	1	COPS2	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DDB2	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
CUL3	17	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	5
CRBN	2	COPS2	5	affinity chromatography technology	Kroenke J (2014)	1
CUL3	17	KLHL18	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Moghe S (2012), Moghe S (2012), Huttlin EL (2017)	5
FBXO7	1	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
RFWD2	0	COPS8	2	biochemical, affinity chromatography technology	Yi C (2002), Olma MH (2009)	2
COPS8	2	CRBN	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Kroenke J (2014)	2
DDB1	6	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006), Jin J (2006), Higa LA (2006), Rossi M (2013), Shibata E (2011), Higa LA (2006), Higa LA (2006)	8
DDB1	6	SKP2	2	affinity chromatography technology	Bondar T (2006)	1
COPS3	1	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	4
COPS5	0	KCTD10	1	affinity chromatography technology, genetic interference	Bennett EJ (2010), Horlbeck MA (2018)	2
CUL1	7	PPP1CC	2	affinity chromatography technology	Bennett EJ (2010)	1
NEDD8	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012)	4
TRAF2	1	IKBKB	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Devin A (2001), Li S (2009), Li S (2009), Li HY (2008), Shen RR (2012), Shen RR (2012), Zhang W (2010), Chen TC (2014), Mei ZZ (2016)	9
RFWD2	0	COPS3	1	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
COPS5	0	JUN	0	two hybrid, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Claret FX (1996), Claret FX (1996), Claret FX (1996), Bianchi E (2000), Yun HM (2010)	5
VCP	6	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Bennett EJ (2010), Besten Wd (2012)	3
PGR	1	COPS5	0	two hybrid, pull down	Chauchereau A (2000), Chauchereau A (2000)	2
CAND1	2	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chua YS (2011), Chua YS (2011), Tron AE (2012), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Liu J (2002), Huttlin EL (2017)	8
CRBN	2	DDA1	1	affinity chromatography technology	Kroenke J (2014)	1
ABCA1	5	COPS5	0	affinity chromatography technology, affinity chromatography technology	Azuma Y (2009), Azuma Y (2009)	2
CDK2	0	NEDD8	0	affinity chromatography technology	Ewing RM (2007)	1
COPS3	1	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	3
CUL4B	8	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Min KW (2003), Bennett EJ (2010), Bennett EJ (2010), Hein MY (2015)	6
DDB1	6	GPS1	1	affinity chromatography technology, pull down, fluorescent resonance energy transfe	Jin J (2006), Emberley ED (2012), Cavadini S (2016)	3
PEA15	0	COPS5	0	two hybrid, affinity chromatography technology, enzymatic study	Nagarajan A (2014), Nagarajan A (2014), Nagarajan A (2014)	3
CUL3	17	CTNNB1	30	affinity chromatography technology	Bennett EJ (2010)	1
NEDD8	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010)	3
CUL4A	2	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010), Jin J (2006), Huttlin EL (2017)	4
BTBD1	2	BTBD2	4	affinity chromatography technology	Huttlin EL (2017)	1
COPS8	2	COPS7B	0	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	5
CUL1	7	DCAF1	5	affinity chromatography technology	McCall CM (2008)	1
CUL4B	8	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Higa LA (2006), Bennett EJ (2010), Jin J (2006), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	9
ITGB2	4	COPS5	0	pull down, two hybrid	Bianchi E (2000), Bianchi E (2000)	2
CUL3	17	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
COPS5	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang XC (2008), Zhang XC (2008), Zhang XC (2008), Wang J (2006), Bech-Otschir D (2001), Bech-Otschir D (2001), Oh W (2006), Bhansali M (2014), Bhansali M (2014)	9
COPS5	0	KLHL24	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
COPS6	0	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
ERCC8	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Olma MH (2009)	3
COPS2	5	ABCA1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Azuma Y (2009), Zhang M (2016), Zhang M (2016)	3
ERCC8	1	COPS2	5	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2
BCL3	2	NCOA1	6	two hybrid, pull down	Na SY (1999), Na SY (1999)	2
BCL3	2	NFKB1	2	affinity chromatography technology, imaging technique, pull down, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Thornburg NJ (2003), Thornburg NJ (2003), Naumann M (1993), Naumann M (1993), Naumann M (1993), Heissmeyer V (1999), Keutgens A (2010), Keutgens A (2010), Kim JH (2005), Choi HJ (2010)	10
COPS5	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology	Guo H (2016), Guo H (2016)	2
CUL3	17	LRR1	1	affinity chromatography technology	Wimuttisuk W (2014)	1
CUL2	3	TXN	1	affinity chromatography technology	Bennett EJ (2010)	1
COPS8	2	DCAF11	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
DCAF4	3	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Hein MY (2015), Huttlin EL (2017)	3
AHR	3	NCOA1	6	pull down, affinity chromatography technology, two hybrid, pull down	Watt K (2005), Beischlag TV (2002), Beischlag TV (2002), Beischlag TV (2002)	4
COPS6	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Olma MH (2009)	5
CUL4A	2	CTNNB1	30	affinity chromatography technology	Tripathi R (2007)	1
COPS6	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Enchev RI (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
KLHL13	0	KLHL22	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Maerki S (2009), Huttlin EL (2017)	3
CUL2	3	SKP2	2	affinity chromatography technology	Kimura Y (2007)	1
DDA1	1	CAND1	2	affinity chromatography technology	Behrends C (2010)	1
DDB1	6	COPS8	2	affinity chromatography technology, pull down	Angers S (2006), Emberley ED (2012)	2
COPS5	0	FBXO7	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
CTNNB1	30	COPS8	2	affinity chromatography technology	Huang X (2009)	1
CUL5	1	COPS2	5	affinity chromatography technology	Bennett EJ (2010)	1
VCP	6	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Besten Wd (2012), Zhang Z (2015)	3
TP53	0	FBXO11	14	affinity chromatography technology, pull down, affinity chromatography technology	Abida WM (2007), Abida WM (2007), Abida WM (2007)	3
COPS5	0	BRSK2	5	affinity chromatography technology, pull down	Zhou J (2012), Zhou J (2012)	2
PPP1CC	2	TP53	0	affinity chromatography technology	Flores-Delgado G (2007)	1
DDB1	6	COPS4	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Olma MH (2009)	4
COPS6	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	6
CUL1	7	DDB1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Gastaldello S (2012)	2
ERN1	1	COPS5	0	affinity chromatography technology, two hybrid, affinity chromatography technology	Hsieh YH (2007), Oono K (2004), Oono K (2004)	3
COPS6	0	FBXO17	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
CHUK	5	COPS5	0	enzymatic study, affinity chromatography technology	Orel L (2010), Asare Y (2013)	2
CDKN1C	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Kamura T (2003), Calvisi DF (2009), Kamura T (2003)	3
COPS3	1	CRBN	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kroenke J (2014)	2
CUL3	17	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sumara I (2007), Bennett EJ (2010), Olma MH (2009), Wimuttisuk W (2014), Maerki S (2009), Huttlin EL (2017)	6
SKP2	2	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
DDB1	6	RANBP9	5	biochemical	Havugimana PC (2012)	1
TP53	0	ERN1	1	affinity chromatography technology	Namba T (2015)	1
COPS5	0	CRBN	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Kroenke J (2014)	2
LRR1	1	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
COPS3	1	DCAF4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL4B	8	TOR1AIP2	2	affinity chromatography technology	Bennett EJ (2010)	1
CDKN1B	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Miranda-Carboni GA (2008), Bondar T (2006), Li B (2006), Li B (2006), Gao J (2015)	5
MAP2K2	2	COPS5	0	two hybrid, two hybrid	Bandyopadhyay S (2010), Wang J (2008)	2
KLHL13	0	COPS4	0	affinity chromatography technology	Sowa ME (2009)	1
COPS5	0	COPS9	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Bennett EJ (2010), Ebina M (2013), Ebina M (2013), Rozen S (2015), Rozen S (2015)	5
CUL5	1	DCAF1	5	affinity chromatography technology	Bennett EJ (2010)	1
COPS8	2	COPS5	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Olma MH (2009), Asare Y (2013), Huttlin EL (2015), Huttlin EL (2017), Boldt K (2016)	9
CTNNB1	30	PTGS2	0	unspecified method, affinity chromatography technology	Kim I (2012), Kim I (2012)	2
CUL4B	8	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015), Yang Y (2015)	4
GPS1	1	COPS7A	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015), Hein MY (2015), Huang X (2016)	6
UCHL1	1	CTNNB1	30	affinity chromatography technology	Bheda A (2009)	1
DDB1	6	COPS5	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009), He F (2013)	6
CDK2	0	CAND1	2	affinity chromatography technology	Neganova I (2011)	1
DDB2	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Olma MH (2009), Hein MY (2015)	6
DDB1	6	CRBN	2	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology	Angers S (2006), Ito T (2010), Chamberlain PP (2014), Liu Y (2015), Diaz-Rodriguez E (2016), Xu Q (2016), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Eichner R (2016), Matyskiela ME (2018), Kroenke J (2014)	12
CUL1	7	TXN	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Olma MH (2009)	2
TP53	0	TP53BP1	3	x-ray crystallography, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, x-ray crystallography, two hybrid, pull down, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, unspecified method	Derbyshire DJ (2002), Sengupta S (2004), Sengupta S (2004), Ekblad CM (2004), Lo KW (2005), Joo WS (2002), Derbyshire DJ (2002), Iwabuchi K (1994), Iwabuchi K (1994), Iwabuchi K (1994), Roy S (2010), Dai C (2011), Tembe V (2015), Cuella-Martin R (2016), Cuella-Martin R (2016), Tong Q (2015), Tong Q (2015)	17
PPP1CC	2	RANBP9	5	two hybrid, two hybrid, affinity chromatography technology	Esteves SL (2012), Fardilha M (2011), Fardilha M (2011)	3
CHUK	5	BCL3	2	enzymatic study	Wang VY (2017)	1
COPS3	1	TOR1AIP2	2	affinity chromatography technology	Olma MH (2009)	1
CUL5	1	S100A7	1	affinity chromatography technology	Bennett EJ (2010)	1
TXN	1	TP53	0	pull down	Stoner CS (2009)	1
AHR	3	NEDD8	0	pull down, affinity chromatography technology	Antenos M (2002), Antenos M (2002)	2
CUL4A	2	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2017)	6
PTGS2	0	VCP	6	affinity chromatography technology	Chen SF (2013)	1
CUL5	1	NFKB1	2	affinity chromatography technology	Bennett EJ (2010)	1
FBXO7	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Kirk R (2008), Hsu JM (2004), Hagens O (2006), Bennett EJ (2010), Hein MY (2015), Vingill S (2016), Huttlin EL (2017), Teixeira FR (2016), Reitsma JM (2017), Reitsma JM (2017)	11
IKBKB	1	COPS7A	0	two hybrid, affinity chromatography technology	Orel L (2010), Orel L (2010)	2
CUL2	3	LRR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Kamura T (2004), Kamura T (2004), Kamura T (2004)	5
BCL3	2	CTNNB1	30	affinity chromatography technology	Kim JH (2005)	1
VCP	6	CUL5	1	affinity chromatography technology	Yu CC (2013)	1
COPS5	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Fang L (2008), Enchev RI (2010), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Asare Y (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	13
TP53	0	PTGS2	0	affinity chromatography technology, biochemical, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	King JG (2001), Choi EM (2009), Choi EM (2009), Choi EM (2009), Tang HY (2006), Tang HY (2006), Lin C (2011), Lin C (2011), Choi EM (2005), Choi EM (2005), Choi EM (2005), Choi EM (2005)	12
YWHAZ	1	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology	Waterman MJ (1998), Waterman MJ (1998), Gu YM (2006)	3
COPS6	0	COPS7A	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	15
CAND1	2	UPF1	8	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Higa LA (2006)	5
DDB2	1	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Hein MY (2015)	4
CUL3	17	KLHL24	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
CUL3	17	COPS8	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Schumacher FR (2015)	2
TP53	0	DCAF1	5	pull down	Kim K (2012)	1
COPS6	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), McCall CM (2008), Bennett EJ (2010), Olma MH (2009)	4
NEDD8	0	DCAF11	2	affinity chromatography technology	Bennett EJ (2010)	1
RFWD2	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Choi HH (2011), Choi HH (2011)	4
COPS8	2	BTBD1	2	affinity chromatography technology	Huttlin EL (2017)	1
VCP	6	TP53BP1	3	affinity chromatography technology	Yu CC (2013)	1
COPS5	0	GUCY1A3	0	affinity chromatography technology, affinity chromatography technology	Bhansali M (2014), Bhansali M (2014)	2
DDA1	1	ERCC8	1	affinity chromatography technology	Olma MH (2009)	1
COPS5	0	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2017)	3
VCP	6	COPS7A	0	affinity chromatography technology	Yu CC (2013)	1
COPS8	2	COPS6	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	10
DDB1	6	CTNNB1	30	affinity chromatography technology	Kawajiri K (2009)	1
CUL1	7	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Min KW (2005), Min KW (2005), Yang X (2002), Yang X (2002), Huang X (2005), Bennett EJ (2010), Scherer PC (2016), Scherer PC (2016), Reitsma JM (2017)	9
HNRNPL	3	KLHL9	1	affinity chromatography technology	Fei T (2017)	1
MDM2	2	JUND	2	pull down	Miyamoto-Sato E (2010)	1
GFER	1	COPS8	2	affinity chromatography technology	Wang Y (2004)	1
COPS5	0	KLHL15	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
ITGB2	4	RANBP9	5	two hybrid, pull down, affinity chromatography technology	Denti S (2004), Denti S (2004), Denti S (2004)	3
COPS5	0	FNIP1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GPS1	1	COPS7B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Stotland A (2012), Havugimana PC (2012), Huang X (2016), Huttlin EL (2017)	4
COPS5	0	SKP2	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
DDB1	6	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Jin J (2006), Groisman R (2003), Groisman R (2003), Meulenbroek EM (2012), Fei J (2012), Jin J (2006), He J (2016), Groisman R (2006), Chitale S (2017), Ohtake F (2007)	10
COPS5	0	FBXO17	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
RFWD2	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Higa LA (2006), He YJ (2006), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Lu G (2014)	7
S100A7	1	COPS5	0	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Emberley ED (2003), Emberley ED (2003), Emberley ED (2005), Emberley ED (2005)	4
CUL3	17	CUL4B	8	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	KLHL18	2	affinity chromatography technology	Olma MH (2009)	1
TP53	0	CDKN1C	0	affinity chromatography technology	Kikuchi J (2003)	1
CUL5	1	TOP2A	2	affinity chromatography technology	Bennett EJ (2010)	1
ERCC8	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2
COPS5	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Neuss H (2007), Fang L (2008), Orel L (2010), Uhle S (2003), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	17
HNRNPL	3	GUCY1A3	0	affinity chromatography technology	Fei T (2017)	1
COPS5	0	PPP1CC	2	affinity chromatography technology, two hybrid, two hybrid	Bennett EJ (2010), Esteves SL (2012), Fardilha M (2011)	3
CUL3	17	KLHL22	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sumara I (2007), Bennett EJ (2010), Olma MH (2009), Maerki S (2009), Huttlin EL (2017), Ferretti LP (2016)	6
CDKN1B	1	DDB1	6	affinity chromatography technology	Iovine B (2011)	1
DCAF1	5	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Hrecka K (2007), Olma MH (2009)	3
GFER	1	GPS1	1	affinity chromatography technology	Wang Y (2004)	1
AHR	3	SMAD4	9	affinity chromatography technology, affinity chromatography technology	Lee CC (2016), Lee CC (2016)	2
HIF1A	1	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Chen D (2003), Ravi R (2000), Hansson LO (2002), An WG (1998), An WG (1998), Chowdhury AR (2017), Chowdhury AR (2017), Suzuki H (2001), Sanchez-Puig N (2005)	9
DDA1	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
CUL4A	2	KLHL9	1	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	12
BCL3	2	COPS5	0	two hybrid, pull down, affinity chromatography technology	Dechend R (1999), Dechend R (1999), Dechend R (1999)	3
DCAF11	2	VCP	6	biochemical	Kristensen AR (2012)	1
COPS6	0	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009)	5
COPS6	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	5
COPS6	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Sharon M (2009), Bennett EJ (2010), Lingaraju GM (2014), Huttlin EL (2015), Huttlin EL (2017)	7
PTGS2	0	APP	1	affinity chromatography technology, affinity chromatography technology	Nagano S (2004), Nagano S (2004)	2
COPS8	2	DTL	0	affinity chromatography technology	Huttlin EL (2017)	1
COPS4	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	3
CUL2	3	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Menon S (2008), Mao X (2011), Chua YS (2011), Chua YS (2011), Tron AE (2012)	7
COPS3	1	KLHL15	1	affinity chromatography technology	Huttlin EL (2015)	1
DDA1	1	DTL	0	affinity chromatography technology	Olma MH (2009)	1
COPS2	5	BTBD2	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MDM2	2	HIF1A	1	pull down, affinity chromatography technology, enzymatic study, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Chen D (2003), Chen D (2003), Ravi R (2000), Lee YM (2009), Lee YM (2009), Lee YM (2009), Maroni P (2014), Amelio I (2015), Yoo YG (2004), LaRusch GA (2007), LaRusch GA (2007), Nieminen AL (2005)	12
COPS7B	0	COPS7A	0	biochemical, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2017)	2
DDA1	1	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
JUND	2	COPS5	0	imaging technique, affinity chromatography technology	Claret FX (1996), Bennett EJ (2010)	2
PTGS2	0	COPS3	1	affinity chromatography technology	Neuss H (2007)	1
DDA1	1	DDB2	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Hein MY (2015)	2
COPS6	0	KLHL22	3	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
CUL4B	8	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Fei J (2012), Hein MY (2015)	3
COPS5	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Fang L (2008), Sharon M (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Choi HH (2011), Kristensen AR (2012), Birol M (2014), Birol M (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	18
SMAD4	9	CTNNB1	30	affinity chromatography technology	Tian YC (2002)	1
PDLIM7	0	COPS5	0	pull down, affinity chromatography technology, affinity chromatography technology	Sangadala S (2013), Sangadala S (2013), Sangadala S (2013)	3
DCAF4	3	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
KLHL13	0	KLHL9	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sumara I (2007), Sumara I (2007), Maerki S (2009), Maerki S (2009)	5
CUL4A	2	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), He YJ (2006), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Huttlin EL (2017), Lo JY (2017)	10
CUL5	1	BTBD1	2	affinity chromatography technology	Bennett EJ (2010)	1
BTBD1	2	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
CDK2	0	TXN	1	affinity chromatography technology	Neganova I (2011)	1
KLHL9	1	KLHL22	3	affinity chromatography technology, affinity chromatography technology	Maerki S (2009), Huttlin EL (2017)	2
NEDD8	0	UCHL1	1	two hybrid	Stelzl U (2005)	1
IKBKB	1	TP53	0	enzymatic study	Xia Y (2009)	1
GNB5	2	COPS5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
OPRM1	0	RANBP9	5	two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Petko J (2013), Petko J (2013), Talbot JN (2009), Talbot JN (2009), Talbot JN (2009)	5
RFWD2	0	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Jin J (2006), He YJ (2006), Olma MH (2009), Lu G (2014), Lu G (2014)	6
TP53BP1	3	YWHAZ	1	affinity chromatography technology	Woods NT (2012)	1
DCAF4	3	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
CUL4A	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Angers S (2006), Bennett EJ (2010), Bennett EJ (2010), Sertic S (2013)	5
TP53	0	TOP2A	2	affinity chromatography technology, pull down, genetic interference	Cowell IG (2000), Cowell IG (2000), Xie L (2013)	3
DCAF1	5	COPS7B	0	affinity chromatography technology	McCall CM (2008)	1
LRR1	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	4
NCOA1	6	NFKB1	2	pull down, pull down	Lee SK (2000), Na SY (1998)	2
TP53BP1	3	RACK1	2	affinity chromatography technology	Woods NT (2012)	1
COPS5	0	KLHL13	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Bennett EJ (2010)	3
RFWD2	0	COPS5	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
DDB2	1	ERCC8	1	affinity chromatography technology	Groisman R (2003)	1
CUL5	1	DCAF11	2	affinity chromatography technology	Bennett EJ (2010)	1
DTL	0	TP53	0	affinity chromatography technology, enzymatic study	Banks D (2006), Banks D (2006)	2
COPS4	0	COPS7A	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Sharon M (2009), Luke-Glaser S (2007), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016)	13
VCP	6	TPD52L2	0	affinity chromatography technology	Fogeron ML (2013)	1
CTNNB1	30	IKBKB	1	affinity chromatography technology, pull down, imaging technique	Lamberti C (2001), Lamberti C (2001), Chen TC (2014)	3
SKP2	2	COPS2	5	affinity chromatography technology	Huttlin EL (2017)	1
COPS3	1	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	5
CRBN	2	GPS1	1	affinity chromatography technology	Kroenke J (2014)	1
GPS1	1	COPS4	0	affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical	Stotland A (2012), Tsuge T (2001), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015)	7
VCP	6	COPS3	1	affinity chromatography technology	Yu CC (2013)	1
HNRNPL	3	PEA15	0	affinity chromatography technology	Fei T (2017)	1
CUL4B	8	S100A7	1	affinity chromatography technology	Bennett EJ (2010)	1
COPS2	5	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Yang X (2002), Choo YY (2011), Bennett EJ (2010), Huttlin EL (2015), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	7
COPS6	0	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	9
CTNNB1	30	CUL1	7	affinity chromatography technology	Read MA (2000)	1
NEDD8	0	KLHL22	3	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	RACK1	2	two hybrid, affinity chromatography technology	Wang J (2008), Bennett EJ (2010)	2
COPS2	5	COPS9	1	affinity chromatography technology	Rozen S (2015)	1
CTNNB1	30	APP	1	pull down	Olah J (2011)	1
HUS1	1	RAD1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Volkmer E (1999), Volkmer E (1999), Hang H (2002), Hirai I (2004), Warmerdam DO (2010), Huttlin EL (2015), Huttlin EL (2017)	7
COPS5	0	FBXO11	14	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
NEDD8	0	DCAF1	5	affinity chromatography technology	Bennett EJ (2010)	1
DDA1	1	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Behrends C (2010), Hrecka K (2007), Hrecka K (2007), Olma MH (2009), Olma MH (2009), Wan C (2015)	6
SMAD4	9	SKP2	2	affinity chromatography technology, affinity chromatography technology, pull down	Yang L (2006), Liang M (2004), Liang M (2004)	3
COPS5	0	TRAF2	1	affinity chromatography technology, affinity chromatography technology	Wang J (2006), Wang J (2006)	2
CUL4A	2	GNB5	2	affinity chromatography technology	Zha Z (2015)	1
RACK1	2	CUL2	3	affinity chromatography technology	Zhang W (2008)	1
CUL5	1	FBXO17	1	affinity chromatography technology	Bennett EJ (2010)	1
YWHAZ	1	COPS7B	0	affinity chromatography technology	Hein MY (2015)	1
CUL5	1	COPS3	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
GNB5	2	APP	1	pull down	Olah J (2011)	1
JUND	2	RFWD2	0	affinity chromatography technology, two hybrid	Bianchi E (2003), Kobayashi S (2013)	2
CUL4A	2	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Hein MY (2015)	7
MDM2	2	UCHL1	1	affinity chromatography technology	Li L (2010)	1
CHUK	5	CUL1	7	affinity chromatography technology	Kumar A (2007)	1
CUL4B	8	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Hein MY (2015), Higa LA (2006)	3
COPS5	0	TXN	1	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Bennett EJ (2010), Hwang CY (2004), Hwang CY (2004), Hwang CY (2004), Hwang CY (2004), Hwang CY (2004)	6
NEDD8	0	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
IKBKB	1	NFKB1	2	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, imaging technique	Heissmeyer V (2001), Heissmeyer V (1999), Beinke S (2002), Beinke S (2002), Beinke S (2002), Chen TC (2014)	6
CUL2	3	LRRC14	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
SMAD5	2	COPS5	0	two hybrid, affinity chromatography technology	Haag J (2006), Haag J (2006)	2
CUL4A	2	CUL1	7	biochemical	He YJ (2006)	1
DDB2	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
COPS2	5	JUN	0	affinity chromatography technology	Huang X (2005)	1
MDM2	2	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Wang L (2011), Wang L (2011)	2
RFWD2	0	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dornan D (2006), Dornan D (2004), Dornan D (2004), Dornan D (2004), Dornan D (2004), Choi HH (2011), Yamada T (2013), Zou S (2016)	8
DDB1	6	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006), Huttlin EL (2017)	4
RFWD2	0	DCAF1	5	affinity chromatography technology	Olma MH (2009)	1
DTL	0	FBXO11	14	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Rossi M (2013), Rossi M (2013), Rossi M (2013), Dar A (2014)	4
RANBP9	5	S100A7	1	two hybrid, pull down	Emberley ED (2002), Emberley ED (2002)	2
FBXO17	1	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IKBKB	1	COPS3	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Orel L (2010), Orel L (2010), Asare Y (2013)	3
CAND1	2	RACK1	2	affinity chromatography technology	Bennett EJ (2010)	1
LRR1	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
CCNDBP1	0	COPS5	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Takami T (2005), Takami T (2005), Takami T (2005)	3
TRAF2	1	JUN	0	enzymatic study	Park KJ (2003)	1
COPS5	0	DDB2	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), He YJ (2006), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
CUL5	1	COPS9	1	affinity chromatography technology	Bennett EJ (2010)	1
AHR	3	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Kawajiri K (2009), Kasai S (2013)	2
BTBD1	2	LRR1	1	affinity chromatography technology	Wimuttisuk W (2014)	1
NEDD8	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010)	3
NEDD8	0	KLHL9	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL1	7	XRN2	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	KLHL15	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Oberg EA (2012), Huttlin EL (2017), Ferretti LP (2016)	4
CUL4B	8	TP53	0	affinity chromatography technology	Thirunavukarasou A (2014)	1
CUL5	1	DDB2	1	affinity chromatography technology	Bennett EJ (2010)	1
DDA1	1	COPS8	2	affinity chromatography technology	Olma MH (2009)	1
CUL5	1	CCNDBP1	0	two hybrid	Rolland T (2014)	1
COPS3	1	KLHL18	2	affinity chromatography technology	Olma MH (2009)	1
COPS6	0	KLHL15	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
LRR1	1	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
CUL2	3	COPS9	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL2	3	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009)	3
COPS6	0	TXN	1	affinity chromatography technology	Bennett EJ (2010)	1
NEDD8	0	COPS9	1	affinity chromatography technology	Bennett EJ (2010)	1
SMAD7	1	ZEB1	3	affinity chromatography technology, affinity chromatography technology, pull down	Nakahata S (2010), Nakahata S (2010), Nakahata S (2010)	3
COPS7A	0	DTL	0	affinity chromatography technology	Hein MY (2015)	1
NFKB1	2	CHUK	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Heissmeyer V (1999), Beinke S (2002), Beinke S (2002), Beinke S (2002)	4
CDK2	0	UCHL1	1	affinity chromatography technology	Neganova I (2011)	1
DDA1	1	TOR1AIP2	2	affinity chromatography technology	Olma MH (2009)	1
NCOA1	6	VCP	6	affinity chromatography technology	Jung SY (2005)	1
TOP2A	2	CUL2	3	affinity chromatography technology	Yun J (2009)	1
CUL5	1	COPS7A	0	affinity chromatography technology	Bennett EJ (2010)	1
GPS1	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Stotland A (2012), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Scherer PC (2016)	5
CUL3	17	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
DDB2	1	COPS8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
COPS3	1	BTBD2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	3
DDB2	1	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDK2	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
COPS5	0	NFKB1	2	affinity chromatography technology, two hybrid	Bennett EJ (2010), Wang J (2011)	2
COPS6	0	LRR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	5
LRRC14	2	COPS3	1	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
FBXW4	0	GPS1	1	affinity chromatography technology	Lockwood WW (2013)	1
CUL1	7	FBXL5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vashisht AA (2009), Salahudeen AA (2009), Liu B (2012), Vinas-Castells R (2013), Moroishi T (2014), Moroishi T (2014), Chen ZW (2015), Wu WD (2016), Huttlin EL (2017)	9
ERN1	1	FBXO11	14	affinity chromatography technology	Zhu X (2014)	1
DCAF1	5	COPS4	0	affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Olma MH (2009)	2
DDB1	6	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Norman JA (2006), Bennett EJ (2010)	3
COPS5	0	FBXL5	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
SMAD7	1	COPS5	0	two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology	Kim BC (2004), Kim BC (2004), Kim BC (2004), Kim BC (2004)	4
SMAD7	1	SKP2	2	affinity chromatography technology	Kim TA (2013)	1
CUL3	17	COPS9	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Ebina M (2013)	2
COPS6	0	FBXO11	14	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
DDA1	1	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Lu G (2014)	2
COPS7A	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
VCP	6	BRSK2	5	affinity chromatography technology, affinity chromatography technology, pull down	Wang Y (2013), Wang Y (2013), Wang Y (2013)	3
COPS5	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), He F (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
COPS6	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
COPS5	0	CIPC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	3
FBXW4	0	COPS4	0	affinity chromatography technology	Lockwood WW (2013)	1
IKBKB	1	CHUK	5	affinity chromatography technology, biochemical, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Zandi E (1997), Chen G (2002), Otsuki T (2002), May MJ (2000), May MJ (2000), Woronicz JD (1997), Woronicz JD (1997), Deng L (2000), Yeung KC (2001), Mercurio F (1997), Mercurio F (1997), Rothwarf DM (1998), Wu ZH (2010), Li S (2011), Li S (2011), May MJ (2002), Heilker R (1999), Leotoing L (2011), McKenzie FR (2000), Zandi E (1998), Lee DF (2007), Li XH (2001), Yeh PY (2011), Yeh PY (2011), Stehlik C (2002), Li Q (2006), So J (2015), Chen TC (2014), Karim ZA (2015), Huttlin EL (2017)	30
COPS3	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
ERCC8	1	COPS8	2	affinity chromatography technology, affinity chromatography technology, biochemical	Groisman R (2003), Groisman R (2003), Groisman R (2006)	3
COPS6	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2017)	3
CUL3	17	HNRNPL	3	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	RACK1	2	affinity chromatography technology	Neganova I (2011)	1
MDM2	2	APP	1	pull down	Miyamoto-Sato E (2010)	1
COPS5	0	HIF1A	1	affinity chromatography technology, pull down, affinity chromatography technology	Bemis L (2004), Bemis L (2004), No YR (2015)	3
MAP2K2	2	TXN	1	biochemical	Wan C (2015)	1
PTGS2	0	CUL4A	2	affinity chromatography technology	Neuss H (2007)	1
RAD9A	1	HUS1	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dufault VM (2003), Dufault VM (2003), Volkmer E (1999), Volkmer E (1999), Griffith JD (2002), Hirai I (2002), Huttlin EL (2015), Huttlin EL (2017)	8
CUL4B	8	APP	1	pull down	Olah J (2011)	1
COPS5	0	DDA1	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
VCP	6	MDM2	2	affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Okoro DR (2013)	2
CUL1	7	FBXO22	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Liu B (2012), Reitsma JM (2017)	3
COPS6	0	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009)	4
CUL3	17	RACK1	2	affinity chromatography technology	Bennett EJ (2010)	1
FBXL5	3	COPS6	0	affinity chromatography technology	Huttlin EL (2017)	1
FBXW4	0	COPS8	2	affinity chromatography technology	Lockwood WW (2013)	1
VCP	6	YWHAZ	1	affinity chromatography technology, two hybrid	Yu CC (2013), Wang J (2011)	2
RACK1	2	TYK2	1	affinity chromatography technology, pull down	Usacheva A (2003), Usacheva A (2003)	2
NEDD8	0	KCTD10	1	affinity chromatography technology	Bennett EJ (2010)	1
CHUK	5	TRAF2	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Regnier CH (1997), Devin A (2001), Li S (2009), Shen RR (2012), Zhang W (2010), Chen TC (2014)	6
DDB2	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	6
CUL5	1	CUL2	3	affinity chromatography technology	Bennett EJ (2010)	1
COPS7A	0	KLHL13	0	affinity chromatography technology	Hein MY (2015)	1
MIF	1	TP53	0	affinity chromatography technology	Jung H (2008)	1
TRAF2	1	RACK1	2	affinity chromatography technology	Lin J (2015)	1
CUL1	7	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Min KW (2003), Menon S (2008), Chew EH (2007), Min KW (2005), Min KW (2005), Min KW (2005), Hwang JW (2003), Hwang JW (2003), Mao X (2011), Chua YS (2011), Chua YS (2011), Tron AE (2012), Zheng J (2002), Zheng J (2002), Bornstein G (2006), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), He YJ (2006), Emberley ED (2012), Choo YY (2011), Jonason JH (2007), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Liu J (2002), Liu J (2002), Liu J (2002), Liu J (2002), Korzeniewski N (2012), Pierce NW (2013), Kim AY (2008), Zhang S (2016), Tikhmyanova N (2017), Tikhmyanova N (2017), Reitsma JM (2017), Reitsma JM (2017)	41
CTNNB1	30	CHUK	5	affinity chromatography technology, pull down, enzymatic study	Lamberti C (2001), Lamberti C (2001), Albanese C (2003)	3
CUL4B	8	COPS9	1	affinity chromatography technology	Bennett EJ (2010)	1
SKP2	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Min KW (2003), Lisztwan J (1998), Lisztwan J (1998), Marti A (1999), Zheng N (2002), Menon S (2008), Chew EH (2007), Chew EH (2007), Ji P (2006), Sabile A (2006), Tan P (1999), Lin HK (2009), Nie L (2011), Chua YS (2011), Huang Z (2004), Wu J (2012), Koyama-Nasu R (2007), Bashir T (2010), Saiga T (2009), Choo YY (2011), Jonason JH (2007), Jonason JH (2007), Bennett EJ (2010), Michel JJ (1998), Carrano AC (1999), Lyapina SA (1998), Lyapina SA (1998), Wu J (2012), Yu ZK (1998), Yu ZK (1998), Rodier G (2008), Swarnalatha M (2013), Cordero-Espinoza L (2013), Yumimoto K (2013), Chung FZ (2014), Zhou W (2014), Zhou W (2014), Yumimoto K (2012), Zhang S (2016), Zhang S (2016), Huttlin EL (2017), Kuchay S (2017), Reitsma JM (2017), Reitsma JM (2017), Ma X (2017)	46
FBXO7	1	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
BTBD2	4	TP53	0	two hybrid, affinity chromatography technology	Stelzl U (2005), Stelzl U (2005)	2
CUL5	1	COPS8	2	affinity chromatography technology	Bennett EJ (2010)	1
NFKB1	2	VCP	6	affinity chromatography technology	Zhang Z (2015)	1
JUN	0	CREB3	1	pull down	Miyamoto-Sato E (2010)	1
CUL3	17	IKBKB	1	affinity chromatography technology	Lee DF (2009)	1
COPS4	0	LRRC14	2	affinity chromatography technology	Olma MH (2009)	1
PTGS2	0	CUL1	7	affinity chromatography technology	Neuss H (2007)	1
DCAF11	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Hein MY (2015), Huttlin EL (2017)	3
COPS5	0	TPD52L2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DDB1	6	DCAF1	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Jin J (2006), Jin J (2006), Ahn J (2010), Maddika S (2009), Maddika S (2009), McCall CM (2008), McCall CM (2008), Hrecka K (2007), Hrecka K (2007), Le Rouzic E (2007), Le Rouzic E (2007), Olma MH (2009), Pham TN (2011), Gerard FC (2014), Nakagawa T (2015), Wan C (2015), Kyei GB (2015), Cassiday PA (2015), Gao J (2015), Gao J (2015), Wu Y (2016), Wu Y (2016), Wang H (2017), Zhou X (2016), Zhou X (2016), Wang X (2017)	26
CUL4A	2	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Angers S (2006), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009)	7
COPS3	1	COPS9	1	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology	Huttlin EL (2015), Rozen S (2015), Rozen S (2015), Rozen S (2015), Rozen S (2015), Huttlin EL (2017)	6
JUN	0	JUND	2	affinity chromatography technology	Li X (2015)	1
CUL3	17	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Chua YS (2011), Chua YS (2011), Tron AE (2012), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Schumacher FR (2015), Schumacher FR (2015), Lo SC (2006), Lo SC (2006)	12
HNRNPL	3	CUL5	1	affinity chromatography technology	Fei T (2017)	1
COPS5	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Birol M (2014)	5
CUL1	7	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huang X (2016), Reitsma JM (2017)	3
DDB1	6	CAND1	2	affinity chromatography technology	Hu J (2004)	1
NEDD8	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Wimuttisuk W (2007)	4
RANBP9	5	APP	1	affinity chromatography technology	Lakshmana MK (2009)	1
COPS8	2	COPS4	0	biochemical, affinity chromatography technology, biochemical, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	9
COPS5	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Pick E (2012)	7
VCP	6	HIF1A	1	affinity chromatography technology	Alexandru G (2008)	1
CENPT	0	CENPW	1	affinity chromatography technology, fluorescent resonance energy transfe	Chun Y (2013), Abendroth C (2015)	2
CUL3	17	KCTD10	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Huttlin EL (2017), Ren K (2014), Pinkas DM (2017), Dubiel D (2017)	6
BTBD2	4	CDK2	0	two hybrid	Wang J (2011)	1
HNRNPL	3	HIF1A	1	affinity chromatography technology	Fei T (2017)	1
LRR1	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	3
COPS5	0	SMAD4	9	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Wan M (2002), Wan M (2002), Wan M (2002), Wan M (2002), Kim BC (2004), Huang J (2007), Sangadala S (2013), Lee CC (2016), Lee CC (2016)	9
COPS5	0	APP	1	pull down, affinity chromatography technology	Olah J (2011), Wang H (2013)	2
UCHL1	1	RANBP9	5	two hybrid	Caballero OL (2002)	1
HIF1A	1	NEDD8	0	affinity chromatography technology, affinity chromatography technology, pull down	Ryu JH (2011), Ryu JH (2011), Ryu JH (2011)	3
DDA1	1	COPS7B	0	affinity chromatography technology	Olma MH (2009)	1
COPS9	1	GPS1	1	affinity chromatography technology, biochemical	Rozen S (2015), Rozen S (2015)	2
CENPT	0	COPS5	0	affinity chromatography technology, affinity chromatography technology, pull down, biochemical	Chun Y (2013), Chun Y (2013), Chun Y (2013), Chun Y (2013)	4
CDKN1B	1	CUL1	7	unspecified method, pull down	Carrano AC (1999), Enchev RI (2012)	2
COPS6	0	LRRC14	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
ERCC8	1	GPS1	1	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2
COPS5	0	KLHL9	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
YWHAZ	1	MDM2	2	affinity chromatography technology	Zhang B (2017)	1
NCOA1	6	JUN	0	pull down, pull down, two hybrid, pull down	Lee SK (1999), Lee SK (2000), Lee SK (1998), Lee SK (1998)	4