PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
PDLIM7	0	TRADD	0	affinity chromatography technology	Ikeda O (2009)	1
ELAVL1	0	TP53	0	affinity chromatography technology	Galban S (2003)	1
SRSF1	0	EFTUD2	12	biochemical	Havugimana PC (2012)	1
ELAVL1	0	ZMYND11	10	affinity chromatography technology	Abdelmohsen K (2009)	1
HDAC1	4	EP400	19	biochemical	Wan C (2015)	1
ZMYND11	10	SRSF10	0	affinity chromatography technology	Guo R (2014)	1
UBE2I	0	TRAF6	0	enzymatic study, enzymatic study	Li Y (2013), Pham LV (2008)	2
NCOR1	9	UBE2I	0	pull down, affinity chromatography technology	Tiefenbach J (2006), Tiefenbach J (2006)	2
PDLIM7	0	TRAF3	1	protein complementation assay, protein complementation assay	Talaty P (2011), Talaty P (2011)	2
MYB	3	PIAS1	4	two hybrid, pull down, pull down	Alm-Kristiansen AH (2011), Ledsaak M (2016), Ledsaak M (2016)	3
SRSF1	0	SNRNP200	15	biochemical	Havugimana PC (2012)	1
ZMYND11	10	MAGOHB	1	affinity chromatography technology	Guo R (2014)	1
SRSF1	0	SRRM2	18	biochemical	Havugimana PC (2012)	1
TRAF6	0	TAB1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Takaesu G (2000), Ninomiya-Tsuji J (1999), Walsh MC (2008)	3
SMARCA2	17	MYB	3	pull down	Kowenz-Leutz E (1999)	1
TAB1	1	TRAF2	1	affinity chromatography technology	Bouwmeester T (2004)	1
TP53	0	PABPC1	5	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
RPL10	3	PABPC1	5	affinity chromatography technology	Hein MY (2015)	1
TRAF6	0	TP53	0	enzymatic study, affinity chromatography technology	Zhang X (2016), Zhang X (2016)	2
TRAF6	0	MYB	3	affinity chromatography technology, affinity chromatography technology	Pham LV (2008), Pham LV (2008)	2
EZH2	4	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	van der Vlag J (1999), van der Vlag J (1999), Caretti G (2004), Tong ZT (2012), Tong ZT (2012), Su L (2012), Su L (2012), Wan C (2015)	8
PNN	2	SRSF4	2	two hybrid, affinity chromatography technology	Zimowska G (2003), Zimowska G (2003)	2
EFTUD2	12	SNRNP200	15	two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Liu S (2006), Liu S (2006), Havugimana PC (2012), Guo R (2014), Wan C (2015), Boldt K (2016)	6
NCOR1	9	SMARCA2	17	biochemical	Havugimana PC (2012)	1
SRPK1	2	ZMYND11	10	enzymatic study	Varjosalo M (2013)	1
TAB1	1	ZMYND11	10	affinity chromatography technology, affinity chromatography technology, two hybrid	Kurozumi K (1998), Kurozumi K (1998), Kurozumi K (1998)	3
ZMYND11	10	SMARCA2	17	affinity chromatography technology	Velasco G (2006)	1
ZMYND11	10	TRADD	0	affinity chromatography technology, affinity chromatography technology	Ikeda O (2009), Ikeda O (2009)	2
ELAVL1	0	SRSF1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
UBE2I	0	PRPF8	14	enzymatic study	Matafora V (2009)	1
TRAF2	1	ZMYND11	10	affinity chromatography technology	Ikeda O (2010)	1
SNRNP200	15	PRPF8	14	two hybrid, two hybrid, biochemical, x-ray crystallography, two hybrid, biochemical, affinity chromatography technology	Liu S (2006), Liu S (2006), Havugimana PC (2012), Mozaffari-Jovin S (2013), Pena V (2007), Wan C (2015), Boldt K (2016)	7
PNN	2	SAP18	1	affinity chromatography technology	Murachelli AG (2012)	1
SMARCA2	17	HDAC1	4	biochemical, affinity chromatography technology, affinity chromatography technology	Sif S (2001), Nakamura T (2002), Hein MY (2015)	3
TRADD	0	TRAF2	1	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Takeuchi M (1996), Park YC (2000), Tsao DH (2000), Tada K (2001), Hsu H (1996), Hsu H (1996), Malinin NL (1997), Vince JE (2009), Jang HD (2001), Park KJ (2003), Lin B (2016)	12
ZMYND11	10	EP400	19	affinity chromatography technology	Zhang W (2007)	1
SRRM1	2	SNRNP200	15	affinity chromatography technology	McCracken S (2005)	1
SRRM1	2	PRPF8	14	affinity chromatography technology, affinity chromatography technology	McCracken S (2005), Le Hir H (2000)	2
ZMYND11	10	PNN	2	affinity chromatography technology	Guo R (2014)	1
SRPK1	2	SRSF1	0	enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, far western blotting, enzymatic study	Lukasiewicz R (2007), Lukasiewicz R (2007), Wang HY (1998), Umehara H (2003), Koizumi J (1999), Koizumi J (1999), Koizumi J (1999), Koizumi J (1999), Varjosalo M (2013)	9
ZMYND11	10	EZH2	4	affinity chromatography technology	Velasco G (2006)	1
SRRM1	2	SRRM2	18	affinity chromatography technology, biochemical, biochemical, biochemical	Blencowe BJ (1998), McCracken S (2005), Havugimana PC (2012), Wan C (2015)	4
GBA	2	ZMYND11	10	affinity chromatography technology	Hein MY (2015)	1
RPL10	3	ZMYND11	10	affinity chromatography technology	Hein MY (2015)	1
ELAVL1	0	ZHX1	1	affinity chromatography technology	Abdelmohsen K (2009)	1
EZH2	4	HIST3H3	0	enzymatic study, enzymatic study, enzymatic study	Sneeringer CJ (2010), Yap DB (2011), Cao Q (2014)	3
ETS2	1	ZMYND11	10	two hybrid, affinity chromatography technology, pull down	Wei G (2003), Wei G (2003), Wei G (2003)	3
E2F6	2	EZH2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Velasco G (2006), Attwooll C (2005), Attwooll C (2005)	3
SRPK1	2	PPIG	1	affinity chromatography technology	Varjosalo M (2013)	1
ZMYND11	10	SRRM2	18	affinity chromatography technology	Guo R (2014)	1
UBE2I	0	HDAC1	4	enzymatic study	Citro S (2013)	1
ZMYND11	10	PABPC1	5	affinity chromatography technology	Guo R (2014)	1
HDAC1	4	HIST3H3	0	enzymatic study, unspecified method	Shi Y (2003), Vermeulen M (2010)	2
UBE2I	0	SRSF1	0	affinity chromatography technology	Pelisch F (2010)	1
UBE2I	0	PDLIM7	0	two hybrid	Rual JF (2005)	1
SRRM2	18	PRPF8	14	biochemical	Wan C (2015)	1
ZHX1	1	ZMYND11	10	two hybrid, two hybrid	Yamada K (2003), Wang J (2011)	2
NCOR1	9	ZMYND11	10	affinity chromatography technology	Masselink H (2000)	1
LTBR	0	TRAF3	1	affinity chromatography technology, genetic interference, pull down, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	VanArsdale TL (1997), Wu MY (1999), Marsters SA (1997), Sanjo H (2010), Sanjo H (2010), Mosialos G (1995), Li C (2003), Li C (2003), Force WR (1997), Force WR (1997), Huttlin EL (2015), Huttlin EL (2017)	12
TP53	0	SMAD2	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Cordenonsi M (2003), Cordenonsi M (2003), Tateossian H (2009), Lu D (2013), Chen TC (2014)	5
ZMYND11	10	UBE2I	0	two hybrid, affinity chromatography technology	Yu B (2009), Yu B (2009)	2
CDK2	0	SAP18	1	affinity chromatography technology	Neganova I (2011)	1
ZMYND11	10	HIST3H3	0	unspecified method, pull down, affinity chromatography technology, unspecified method, pull down	Wang J (2014), Wang J (2014), Wang J (2014), Guo R (2014), Guo R (2014)	5
TRAF2	1	TRAF6	0	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology	Rual JF (2005), Li S (2011), Davies CC (2005), Relaix F (1998), Rolland T (2014), Yu H (2011), Huttlin EL (2017)	7
SRRM1	2	SRSF4	2	affinity chromatography technology, biochemical	Blencowe BJ (1998), McCracken S (2005)	2
TP53	0	SMAD3	1	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Cordenonsi M (2003), Cordenonsi M (2003), Lu D (2013), Ali A (2013)	4
LTBR	0	ZMYND11	10	two hybrid, affinity chromatography technology	Liu HP (2011), Liu HP (2011)	2
TRADD	0	TRAF6	0	affinity chromatography technology, affinity chromatography technology	Chang YL (2014), Chang YL (2014)	2
TRAF2	1	ELAVL1	0	affinity chromatography technology	Herjan T (2013)	1
SRPK1	2	PABPC1	5	affinity chromatography technology	Varjosalo M (2013)	1
TRAF5	1	TRAF2	1	affinity chromatography technology, pull down, pull down	Li S (2011), Li S (2011), Pullen SS (1998)	3
CDK2	0	ZMYND11	10	affinity chromatography technology	Hein MY (2015)	1
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
E2F6	2	EZH1	1	affinity chromatography technology	Velasco G (2006)	1
ELAVL1	0	SRPK1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
SMAD3	1	HDAC1	4	two hybrid, pull down	Liberati NT (2001), Akiyoshi S (1999)	2
SNRNP200	15	SRRM2	18	biochemical	Wan C (2015)	1
HDAC1	4	ZMYND11	10	affinity chromatography technology	Velasco G (2006)	1
SMAD3	1	ZMYND11	10	two hybrid	Wang J (2011)	1
TP53	0	EP400	19	affinity chromatography technology	Lill NL (1997)	1
SRPK1	2	PRPF8	14	biochemical	Lee CG (2004)	1
SAP18	1	SRSF1	0	biochemical	Havugimana PC (2012)	1
ZMYND11	10	SRSF1	0	affinity chromatography technology	Guo R (2014)	1
PDLIM7	0	TRAF2	1	protein complementation assay, protein complementation assay	Talaty P (2011), Talaty P (2011)	2
EZH2	4	SNRNP200	15	affinity chromatography technology	Cao Q (2014)	1
ZMYND11	10	RNU4-1	0	affinity chromatography technology	Guo R (2014)	1
SRPK1	2	TP53	0	two hybrid, pull down, affinity chromatography technology	Peidis P (2011), Peidis P (2011), Peidis P (2011)	3
PABPC1	5	PRPF8	14	biochemical	Wan C (2015)	1
SMAD2	5	ZMYND11	10	two hybrid	Colland F (2004)	1
SRRM2	18	EFTUD2	12	affinity chromatography technology	McCracken S (2005)	1
TRAF1	0	TRADD	0	affinity chromatography technology, affinity chromatography technology	Hsu H (1996), Wicovsky A (2009)	2
LTBR	0	TRAF5	1	pull down, pull down, pull down	Marsters SA (1997), Li C (2003), Mizushima S (1998)	3
SRSF1	0	SRSF10	0	two hybrid, two hybrid	Hegele A (2012), Hegele A (2012)	2
TAB1	1	RPL10	3	two hybrid	Vinayagam A (2011)	1
H3F3A	1	ZMYND11	10	unspecified method, pull down, x-ray crystallography	Wen H (2014), Wen H (2014), Wen H (2014)	3
HDAC1	4	H3F3A	1	affinity chromatography technology	Hein MY (2015)	1
ZMYND11	10	ZMYND11	10	affinity chromatography technology, two hybrid, x-ray crystallography	Yu B (2009), Yu B (2009), Harter MR (2016)	3
MAGEC2	0	ZMYND11	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Hao J (2014), Hao J (2014), Hao J (2014), Hao J (2014)	4
PDLIM7	0	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down	Jung CR (2010), Jung CR (2010), Jung CR (2010)	3
UBE2I	0	ZHX1	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Wang J (2011), Chen S (2013), Chen S (2013), Chen S (2013)	4
TRAF5	1	SRSF1	0	affinity chromatography technology	Sun D (2011)	1
ZMYND11	10	TRAF6	0	affinity chromatography technology, affinity chromatography technology	Wan J (2006), Ikeda O (2010)	2
ZMYND11	10	SNRNP200	15	affinity chromatography technology	Guo R (2014)	1
CDK2	0	SMAD2	5	enzymatic study	Matsuura I (2004)	1
CDK2	0	EZH2	4	enzymatic study	Chen S (2010)	1
PDLIM7	0	ZMYND11	10	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Wan J (2006), Wan J (2006), Liu HP (2011), Ikeda O (2009)	4
SMAD3	1	PABPC1	5	affinity chromatography technology	Brown KA (2008)	1
ELAVL1	0	SMAD2	5	affinity chromatography technology	Abdelmohsen K (2009)	1
PIAS1	4	SRSF1	0	affinity chromatography technology, affinity chromatography technology	Pelisch F (2010), Pelisch F (2010)	2
ELAVL1	0	PABPC1	5	affinity chromatography technology	Abdelmohsen K (2009)	1
SAP18	1	SRSF10	0	biochemical	Havugimana PC (2012)	1
ZMYND11	10	MYB	3	pull down, two hybrid	Ladendorff NE (2001), Ladendorff NE (2001)	2
TRAF2	1	TRAF3	1	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Li S (2011), He L (2004), He L (2004), Pullen SS (1998)	4
SRSF1	0	SRSF4	2	two hybrid, two hybrid	Hegele A (2012), Hegele A (2012)	2
LTBR	0	TRAF1	0	pull down, affinity chromatography technology, affinity chromatography technology	Marsters SA (1997), Huttlin EL (2015), Huttlin EL (2017)	3
TRAF1	0	ZMYND11	10	affinity chromatography technology	Ikeda O (2010)	1
CDK2	0	UBE2I	0	affinity chromatography technology	Neganova I (2011)	1
EZH2	4	SRSF10	0	affinity chromatography technology	Cao Q (2014)	1
SRRM2	18	ELAVL1	0	affinity chromatography technology	McCracken S (2005)	1
ZMYND11	10	SAP18	1	affinity chromatography technology	Guo R (2014)	1
TRAF3	1	ZMYND11	10	affinity chromatography technology, pull down	Ikeda O (2010), Ikeda O (2010)	2
HIST3H3	0	EMSY	3	unspecified method	Vermeulen M (2010)	1
TRAF5	1	TRAF3	1	affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Li S (2011), He L (2004), Chen TC (2014)	3
PNN	2	PPIG	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin CL (2004), Lin CL (2004), Lin CL (2004), Huttlin EL (2017)	4
CDK2	0	PNN	2	affinity chromatography technology	Neganova I (2011)	1
ZMYND11	10	RNU6-1	0	affinity chromatography technology	Guo R (2014)	1
MYB	3	NCOR1	9	pull down, affinity chromatography technology, pull down	Nomura T (2004), Nomura T (2004), Nomura T (2004)	3
EZH2	4	EFTUD2	12	affinity chromatography technology	Cao Q (2014)	1
TRAF5	1	ZMYND11	10	affinity chromatography technology	Ikeda O (2010)	1
EZH2	4	H3F3A	1	affinity chromatography technology	Hauri S (2016)	1
EZH1	1	EZH2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Margueron R (2008), Margueron R (2008), Shen X (2008)	3
EFTUD2	12	RNU5A-1	0	affinity chromatography technology	Guo R (2014)	1
SRPK1	2	PNN	2	affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2017)	2
UBE2I	0	TRAF3	1	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Miliara S (2013), Miliara S (2013), Miliara S (2013), Miliara S (2013)	4
SMAD3	1	SMAD2	5	affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nakao A (1997), Lebrun JJ (1999), Dumont E (2003), Brown KA (2008), Brown KA (2008), Wu RY (1997), Wu RY (1997), Tang Y (2003), Tang Y (2003), Wang J (2011), Huttlin EL (2015), Huttlin EL (2017)	12
TRAF6	0	TRAF5	1	two hybrid, two hybrid, two hybrid, pull down	Woodsmith J (2012), Rolland T (2014), Yu H (2011), Middleton AJ (2017)	4
TRAF1	0	TRAF3	1	affinity chromatography technology, affinity chromatography technology	Pullen SS (1998), Greenfeld H (2015)	2
SMAD2	5	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wotton D (1999), Wotton D (1999), Takeda M (2004), Lo RS (2001)	4
NCOR1	9	PIAS1	4	pull down, two hybrid, affinity chromatography technology	Tiefenbach J (2006), Tiefenbach J (2006), Tiefenbach J (2006)	3
PDLIM7	0	TRAF6	0	affinity chromatography technology, affinity chromatography technology	Uemura N (2006), Uemura N (2006)	2
SRRM1	2	EFTUD2	12	affinity chromatography technology	McCracken S (2005)	1
SRPK1	2	SRRM2	18	affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015)	2
TRAF1	0	TRAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Takeuchi M (1996), Li S (2011), Li S (2011), Fries KL (1999), He L (2004), Zheng C (2010), Zheng C (2010), Relaix F (1998), Relaix F (1998), Jang HD (2001), Fotin-Mleczek M (2004), Pullen SS (1998), Wicovsky A (2009), Rothe M (1994), Rothe M (1994), Chen TC (2014), Greenfeld H (2015), Huttlin EL (2017)	19
PRPF8	14	EFTUD2	12	far western blotting, pull down, two hybrid, two hybrid, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Achsel T (1998), Achsel T (1998), Liu S (2006), Liu S (2006), Havugimana PC (2012), Pena V (2007), Guo R (2014), Wan C (2015), Boldt K (2016)	9
TP53	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique	Ito A (2002), Wang C (2005), Dohi Y (2008), Jin W (2008), Lei Q (2006), Wu Y (2001), Wu Y (2001), Luo J (2000), Juan LJ (2000), Juan LJ (2000), Juan LJ (2000), Murphy M (1999), Insinga A (2004), Sun JM (2007), Yu XY (2010), Sinha S (2010), Sinha S (2010), Li Y (2012), Di Agostino S (2006), Pavithra L (2009), Pavithra L (2009), Luo J (2000), Chen TC (2014), Park EK (2015), Park EK (2015), Park EK (2015)	26
SRRM2	18	PNN	2	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zimowska G (2003), Zimowska G (2003), Zimowska G (2003), McCracken S (2005), Huttlin EL (2017)	5
ZMYND11	10	EFTUD2	12	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Guo R (2014), Guo R (2014), Guo R (2014), Guo R (2014)	4
ELAVL1	0	SRRM1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
EMSY	3	ZMYND11	10	pull down, affinity chromatography technology, two hybrid	Hughes-Davies L (2003), Hughes-Davies L (2003), Hughes-Davies L (2003)	3
CDK2	0	SMAD3	1	enzymatic study, imaging technique	Matsuura I (2004), Chen TC (2014)	2
UBE2I	0	SNRNP200	15	enzymatic study	Matafora V (2009)	1
PNN	2	SRSF10	0	affinity chromatography technology	Huttlin EL (2017)	1
ZMYND11	10	E2F6	2	affinity chromatography technology	Velasco G (2006)	1
TP53	0	ZHX1	1	two hybrid	Goehler H (2004)	1
SRSF4	2	SRSF10	0	two hybrid, two hybrid	Hegele A (2012), Hegele A (2012)	2
EZH2	4	SRSF1	0	affinity chromatography technology	Cao Q (2014)	1
LTBR	0	TRAF2	1	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marsters SA (1997), Sanjo H (2010), Sanjo H (2010), Li C (2003), Liu HP (2011), Huttlin EL (2015), Huttlin EL (2017)	7
ETS2	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee S (2008), Lee S (2008), Carrero ZI (2016)	3
SRRM1	2	PNN	2	affinity chromatography technology, biochemical	McCracken S (2005), Wan C (2015)	2
ZMYND11	10	EZH1	1	affinity chromatography technology	Velasco G (2006)	1
ZMYND11	10	RNU5A-1	0	affinity chromatography technology	Guo R (2014)	1
ZMYND11	10	SRRM1	2	affinity chromatography technology	Guo R (2014)	1
HDAC1	4	EMSY	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joshi P (2013), Hein MY (2015), Varier RA (2016), Huttlin EL (2017)	4
TRAF5	1	ELAVL1	0	affinity chromatography technology	Herjan T (2013)	1
BMPR1A	5	ZMYND11	10	two hybrid, affinity chromatography technology	Kurozumi K (1998), Kurozumi K (1998)	2
HDAC1	4	E2F6	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
ZMYND11	10	TP53	0	affinity chromatography technology	Zhang W (2007)	1
MYB	3	UBE2I	0	two hybrid, enzymatic study	Bies J (2002), Kanei-Ishii C (2012)	2
CDK2	0	SRRM2	18	affinity chromatography technology	So J (2015)	1
ZMYND11	10	PIAS1	4	two hybrid, affinity chromatography technology	Yu B (2009), Yu B (2009)	2
HOXD4	2	ZMYND11	10	two hybrid	Ravasi T (2010)	1
TP53	0	PIAS1	4	two hybrid, pull down, enzymatic study, pull down, enzymatic study, enzymatic study, imaging technique, pull down	Gallagher WM (1999), Kahyo T (2001), Kahyo T (2001), Schmidt D (2002), Pelisch F (2010), Schmidt D (2002), Chen TC (2014), Okubo S (2004)	8
UBE2I	0	TP53	0	two hybrid, two hybrid, two hybrid, enzymatic study, two hybrid, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Minty A (2000), Gallagher WM (1999), Shen Z (1996), Bernier-Villamor V (2002), Wang J (2008), Spektor TM (2011), Jakobs A (2007), Mohideen F (2009), Lin JY (2004), Bennett RL (2012), Heo KS (2013), Morimoto M (2003), Rodriguez MS (1999), Muller S (2000), Fernandez-Lloris R (2006), Mohan RD (2007), Brandt M (2013), Weger S (2005)	18
TRAF2	1	SRSF1	0	affinity chromatography technology	Sun D (2011)	1
NCOR1	9	ETS2	1	affinity chromatography technology	Myers E (2005)	1
ZMYND11	10	SRSF4	2	affinity chromatography technology	Guo R (2014)	1
CDK2	0	MAGOHB	1	affinity chromatography technology	Neganova I (2011)	1
ZMYND11	10	PRPF8	14	affinity chromatography technology	Guo R (2014)	1
ZMYND11	10	PPIG	1	affinity chromatography technology	Guo R (2014)	1
TRAF1	0	TRAF6	0	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Wang J (2011), Rolland T (2014), Yu H (2011), Huttlin EL (2017)	4
SRRM2	18	SRSF4	2	two hybrid, two hybrid	Hegele A (2012), Hegele A (2012)	2
UBE2I	0	PIAS1	4	two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down	Lee BH (2003), Sapetschnig A (2002), Kahyo T (2001), Bandyopadhyay S (2010), Driscoll JJ (2010), Kahyo T (2001), Yin Y (2012), Gocke CB (2005), van den Akker E (2005), Ogawa H (2009), Schmidt D (2002), Gibbs-Seymour I (2015)	12
EZH2	4	ELAVL1	0	affinity chromatography technology	Cao Q (2014)	1
SRSF1	0	TP53	0	enzymatic study, affinity chromatography technology	Pelisch F (2010), Pelisch F (2010)	2
SRRM1	2	SAP18	1	affinity chromatography technology	McCracken S (2005)	1
PABPC1	5	SNRNP200	15	biochemical	Havugimana PC (2012)	1
TP53	0	NCOR1	9	affinity chromatography technology, imaging technique	Dohi Y (2008), Ali A (2013)	2