Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
TOMM40 10452 RITONAVIR CHEMBL163 PharmGKB

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
TOMM40 rs2075650 G hmg coa reductase inhibitors efficacy yes as part of a three SNP genetic risk score with rs2231142 in ABCG2 and rs10455872 in LPA. Associated allele not explicitly stated but methods reference Chasman et al., so used the associated allele from there [PMID:22331829]. Allele G is associated with decreased response to hmg coa reductase inhibitors as compared to allele A. 27045730 1447986196