PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ELOC	0	ELOB	1	two hybrid, pull down, pull down, pull down, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, two hybrid, affinity chromatography technology, x-ray crystallography, two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, pull down, two hybrid, biochemical, biochemical, two hybrid	Rual JF (2005), Ohh M (1999), Aso T (1995), Li Z (2002), Kinoshita K (2007), Kinoshita K (2007), Kinoshita K (2007), Kinoshita K (2007), Lievens S (2009), Brower CS (1999), Stebbins CE (1999), Pause A (1999), Pause A (1999), Havugimana PC (2012), Wang X (2013), Kristensen AR (2012), Costessi A (2011), Rolland T (2014), Kim DY (2013), Wan C (2015), Yu H (2011)	21
CUL5	1	ELOC	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology	Kamura T (2001), Nishiya T (2011), Wolfe LS (2010), Yu X (2003), Xiao Z (2006), Zhou X (2012), Luo K (2007), Yu Y (2004), Bennett EJ (2010), Salter JD (2012), Muniz JR (2013), Kelsall IR (2013), Han X (2014), Fribourgh JL (2014), Guo Y (2014), Guo Y (2014), Kershaw NJ (2014), Huttlin EL (2017)	18
PPP2R1A	8	EHD1	5	biochemical	Wan C (2015)	1
PDLIM1	1	ARIH2	4	biochemical	Kristensen AR (2012)	1
MDM2	2	PHF7	5	two hybrid	Woodsmith J (2012)	1
NTRK1	1	UBC	7	affinity chromatography technology	Emdal KB (2015)	1
UBE2D3	1	NEDD8	0	biochemical	Wan C (2015)	1
ARIH2	4	CBR3	4	two hybrid	Stelzl U (2005)	1
UBE2N	1	TRIM27	2	two hybrid, affinity chromatography technology	Napolitano LM (2011), Napolitano LM (2011)	2
EEF1G	0	RPL8	2	biochemical	Havugimana PC (2012)	1
ARIH2	4	DLST	3	two hybrid	Stelzl U (2005)	1
NTRK1	1	HK2	3	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	WDR91	2	affinity chromatography technology	Emdal KB (2015)	1
CUL5	1	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017), Zhu Z (2017)	3
UBE2D2	0	UBE2V1	0	biochemical	Havugimana PC (2012)	1
UBE2D3	1	TRIM27	2	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Markson G (2009), Napolitano LM (2011), Napolitano LM (2011), Napolitano LM (2011)	4
CUL5	1	RPL8	2	affinity chromatography technology	Bennett EJ (2010)	1
TRIM27	2	KAT5	1	two hybrid	Rolland T (2014)	1
NTRK1	1	ARIH2	4	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	VCP	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Matsumoto M (2005), Zhong X (2006), Dai RM (2001), Bish RA (2007), Lim JJ (2016), Zhang X (2017)	6
NTRK1	1	PABPN1	0	affinity chromatography technology	Emdal KB (2015)	1
UBE2L6	0	ARIH2	4	two hybrid, affinity chromatography technology, two hybrid	Markson G (2009), Pietschmann K (2012), Rolland T (2014)	3
TULP3	0	ARIH2	4	affinity chromatography technology	Huttlin EL (2017)	1
ARIH2	4	TP53	0	two hybrid, affinity chromatography technology, pull down	Stelzl U (2005), Bae S (2012), Bae S (2012)	3
MDM2	2	UBC	7	pull down, enzymatic study, enzymatic study	Higashitsuji H (2005), Luo J (2013), Poyurovsky MV (2007)	3
UBE2D1	0	ARIH2	4	two hybrid	Markson G (2009)	1
TP53	0	UBC	7	affinity chromatography technology, affinity chromatography technology	Ayroldi E (2014), Ke JY (2014)	2
BMX	0	ARIH2	4	affinity chromatography technology	Huttlin EL (2017)	1
PHF7	5	ARIH2	4	two hybrid	Woodsmith J (2012)	1
ARIH2	4	TRIM27	2	two hybrid	Woodsmith J (2012)	1
NTRK1	1	APEX1	1	affinity chromatography technology	Emdal KB (2015)	1
ELOC	0	ASB9	0	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ravasi T (2010), Kwon S (2010), Lievens S (2009), Debrincat MA (2007), Debrincat MA (2007), Muniz JR (2013), Thomas JC (2013), Andresen CA (2014), Huttlin EL (2015), Huttlin EL (2017)	10
ARIH2	4	UTP14A	0	two hybrid	Stelzl U (2005)	1
UBE2N	1	ARIH2	4	two hybrid, affinity chromatography technology, pull down	Marteijn JA (2009), Marteijn JA (2009), Marteijn JA (2009)	3
ASB9	0	ARIH2	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SOCS6	0	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zadjali F (2011), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
UBC	7	NEDD8	0	affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography	Matsumoto M (2005), Bennett EJ (2010), Singh RK (2012), Singh RK (2012)	4
ZFP41	0	ARIH2	4	affinity chromatography technology	Huttlin EL (2015)	1
ARIH2	4	CCDC33	3	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
IL4R	1	KAT5	1	affinity chromatography technology	Sliva D (1999)	1
MDM2	2	UBE2N	1	pull down	David Y (2011)	1
UBE2E3	0	UBC	7	enzymatic study	Sheng Y (2012)	1
CUL5	1	ELOB	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down	Kamura T (2001), Nie L (2011), Wolfe LS (2010), Yu X (2003), Xiao Z (2006), Zhou X (2012), Luo K (2007), Yu Y (2004), Bennett EJ (2010), Salter JD (2012), Muniz JR (2013), Kelsall IR (2013), Han X (2014), Fribourgh JL (2014), Guo Y (2014), Guo Y (2014), Antonioli M (2014), Kershaw NJ (2014)	18
PARP6	1	ARIH2	4	biochemical	Kristensen AR (2012)	1
NOTCH1	25	ARIH2	4	affinity chromatography technology	Yatim A (2012)	1
UBC	7	UBE2T	0	affinity chromatography technology, affinity chromatography technology	Matsumoto M (2005), Bish RA (2007)	2
UBE2D1	0	TRIM27	2	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Markson G (2009), Napolitano LM (2011), Napolitano LM (2011), Napolitano LM (2011)	4
DLST	3	EEF1G	0	affinity chromatography technology	Malty RH (2017)	1
NEDD8	0	ELOC	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
UBC	7	DLST	3	affinity chromatography technology	Matsumoto M (2005)	1
ARIH2	4	SGCE	2	two hybrid	Stelzl U (2005)	1
NEDD8	0	UBE2D2	0	x-ray crystallography	Sakata E (2007)	1
ARIH2	4	ELOB	1	affinity chromatography technology	Kelsall IR (2013)	1
EHD1	5	ARIH2	4	biochemical	Kristensen AR (2012)	1
PHF7	5	UBE2D4	0	two hybrid	Rolland T (2014)	1
NTRK1	1	CUL5	1	affinity chromatography technology	Emdal KB (2015)	1
MDM2	2	APEX1	1	enzymatic study, affinity chromatography technology	Busso CS (2009), Busso CS (2009)	2
UBE2T	0	ARIH2	4	two hybrid	Markson G (2009)	1
UBE2R2	2	ARIH2	4	two hybrid	Markson G (2009)	1
VCP	6	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Yu CC (2013), Fogeron ML (2013)	3
UBC	7	PABPN1	0	affinity chromatography technology	Matsumoto M (2005)	1
ARIH2	4	PPP2R1A	8	two hybrid	Stelzl U (2005)	1
UBE2D2	0	ARIH2	4	two hybrid	Markson G (2009)	1
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
TP53	0	RPL8	2	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
CUL5	1	TRIM27	2	affinity chromatography technology	Bennett EJ (2010)	1
SOCS6	0	ELOB	1	affinity chromatography technology, affinity chromatography technology	Krebs DL (2002), Zadjali F (2011)	2
NEDD8	0	RPL8	2	affinity chromatography technology	Bennett EJ (2010)	1
DLST	3	PPP2R1A	8	affinity chromatography technology	Malty RH (2017)	1
UBE2E1	1	ARIH2	4	two hybrid	Markson G (2009)	1
KAT5	1	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Legube G (2002), Legube G (2002), Wu Q (2009), Dohmesen C (2008), Dohmesen C (2008), Kim JW (2008)	6
MDM2	2	EEF1A1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Frum R (2007), Frum R (2007), Frum R (2007), Tsai NP (2012), Tsai NP (2012)	5
ARIH2	4	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down	Kelsall IR (2013), Kelsall IR (2013), Kelsall IR (2013), Kelsall IR (2013), Kelsall IR (2013)	5
UBC	7	UBE2D3	1	affinity chromatography technology, two hybrid, x-ray crystallography, pull down, pull down, pull down	Matsumoto M (2005), Vinayagam A (2011), Pruneda JN (2014), Li Y (2014), Poyurovsky MV (2007), Zhang X (2017)	6
ARIH2	4	APEX1	1	biochemical	Kristensen AR (2012)	1
NEDD8	0	ELOB	1	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
TRIM27	2	MDM2	2	affinity chromatography technology, enzymatic study	Chu Y (2011), Chu Y (2011)	2
UBC	7	ELOC	0	pull down	Zhang X (2017)	1
TP53	0	UTP14A	0	pull down, pull down, affinity chromatography technology	Hu L (2011), Hu L (2011), Hu L (2011)	3
UBE2D4	0	TRIM27	2	two hybrid, two hybrid	Markson G (2009), Napolitano LM (2011)	2
NTRK1	1	UGP2	2	affinity chromatography technology	Emdal KB (2015)	1
CUL5	1	PABPN1	0	affinity chromatography technology	Bennett EJ (2010)	1
MDM2	2	UBE2E2	1	pull down, pull down	David Y (2011), Yamauchi T (2014)	2
PYCARD	1	PML	7	affinity chromatography technology, affinity chromatography technology	Dowling JK (2014), Dowling JK (2014)	2
VCP	6	ARIH2	4	affinity chromatography technology	Yu CC (2013)	1
NTRK1	1	RPL8	2	affinity chromatography technology	Emdal KB (2015)	1
EHD1	5	NUBP1	0	biochemical	Kristensen AR (2012)	1
VCP	6	PPP2R1A	8	affinity chromatography technology, affinity chromatography technology	Ohama T (2010), Yakovlev VA (2013)	2
PML	7	KAT5	1	affinity chromatography technology, pull down	Wu Q (2009), Wu Q (2009)	2
ARIH2	4	PABPN1	0	affinity chromatography technology, affinity chromatography technology	Raz V (2014), Raz V (2014)	2
NOTCH1	25	PPP2R1A	8	affinity chromatography technology	Yatim A (2012)	1
TP53	0	KAT5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Legube G (2004), Tyteca S (2006), Tyteca S (2006), Kurash JK (2008), Cheng Z (2008), Cheng Z (2008), Cheng Z (2008), Tang Y (2006), Tang Y (2006), Tang Y (2006), Dai C (2013)	11
NTRK1	1	PML	7	affinity chromatography technology	Emdal KB (2015)	1
UBE2V1	0	UBC	7	pull down	McKenna S (2003)	1
ARIH2	4	UBE2L3	1	two hybrid, two hybrid, pull down, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down	Stelzl U (2005), Markson G (2009), Marteijn JA (2005), Plafker SM (2004), Pietschmann K (2012), Marteijn JA (2009), Kelsall IR (2013), Kelsall IR (2013), Ambivero CT (2014), Marteijn JA (2005), Kelsall IR (2013)	11
UBE2D2	0	UBE2L3	1	biochemical	Havugimana PC (2012)	1
DISC1	6	CEP126	0	two hybrid	Morris JA (2003)	1
ARIH2	4	IL4R	1	two hybrid	Stelzl U (2005)	1
UBE2D2	0	TRIM27	2	two hybrid, two hybrid	Markson G (2009), Napolitano LM (2011)	2
PYCARD	1	ARIH2	4	biochemical, imaging technique	Kawashima A (2017), Kawashima A (2017)	2
TP53	0	PPP2R1A	8	imaging technique, affinity chromatography technology	Chen TC (2014), Kikuchi J (2003)	2
PDLIM1	1	NUBP1	0	biochemical	Kristensen AR (2012)	1
NTRK1	1	EEF1A1	0	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	CBR3	4	pull down	Nathan JA (2013)	1
ARIH2	4	EEF1A1	0	two hybrid	Stelzl U (2005)	1
NTRK1	1	EML4	1	affinity chromatography technology	Emdal KB (2015)	1
ARIH2	4	KAT5	1	two hybrid	Stelzl U (2005)	1
UGP2	2	ARIH2	4	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
ARIH2	4	PTN	0	two hybrid	Stelzl U (2005)	1
TP53	0	EEF1A1	0	affinity chromatography technology	Fogeron ML (2013)	1
MDM2	2	UBE2E3	0	pull down, pull down	David Y (2011), Yamauchi T (2014)	2
UBE2E2	1	ARIH2	4	two hybrid	Markson G (2009)	1
PPP2R1A	8	ENSA	0	affinity chromatography technology	Yadav L (2017)	1
ARIH2	4	WDR91	2	two hybrid	Stelzl U (2005)	1
UBE2D1	0	UBC	7	x-ray crystallography	Bosanac I (2010)	1
ARIH2	4	RPL8	2	two hybrid	Stelzl U (2005)	1
TP53	0	PML	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kurki S (2003), Kurki S (2003), Fogal V (2000), Fogal V (2000), Guo A (2000), Guo A (2000), Insinga A (2004), Chu Y (2011), Li Q (2011), Li Q (2011), Bernassola F (2005), Yang Q (2013), Yang Q (2013), Catalano A (2004), Chen TC (2014)	15
UBC	7	UBE2N	1	affinity chromatography technology, enzymatic study, enzymatic study, x-ray crystallography, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down	Matsumoto M (2005), Scheper J (2010), Wu PY (2003), McKenna S (2003), Wiener R (2012), Ye Y (2003), Bish RA (2007), Juang YC (2012), Pastushok L (2007), Singh RK (2012), McKenna S (2001), McKenna S (2001)	12
NTRK1	1	EEF1G	0	affinity chromatography technology	Emdal KB (2015)	1
TP53	0	UBE2N	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Laine A (2006), Laine A (2006), Laine A (2006), Topisirovic I (2009), Topisirovic I (2009)	5
PAPSS2	3	ARIH2	4	biochemical	Kristensen AR (2012)	1
ASB9	0	ELOB	1	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, biochemical, affinity chromatography technology, affinity chromatography technology	Kwon S (2010), Kwon S (2010), Muniz JR (2013), Thomas JC (2013), Andresen CA (2014), Huttlin EL (2017)	6
ASB9	0	UBE2D1	0	pull down	Kwon S (2010)	1
NLRP3	2	ARIH2	4	affinity chromatography technology	Kawashima A (2017)	1
CUL5	1	UBC	7	affinity chromatography technology, pull down	Bennett EJ (2010), Zhang X (2017)	2
NTRK1	1	PPP2R1A	8	affinity chromatography technology	Emdal KB (2015)	1
UBE2E3	0	ARIH2	4	two hybrid	Markson G (2009)	1
CUL5	1	WSB2	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
ARIH2	4	RHEB	2	two hybrid	Wang J (2011)	1
UBE2R2	2	UBE2D2	0	biochemical	Wan C (2015)	1
TRIM27	2	UBE2E3	0	two hybrid, two hybrid	Napolitano LM (2011), Napolitano LM (2011)	2
WSB2	1	ARIH2	4	affinity chromatography technology	Huttlin EL (2017)	1
ARIH2	4	CEP126	0	two hybrid	Stelzl U (2005)	1
MDM2	2	UBE2D3	1	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Yadavilli S (2009), Nie J (2010), Minsky N (2004), Wang X (2011), Sionov RV (2001), Oh W (2010), Zhu Y (2009), Latini P (2011), Jung CR (2010), David Y (2011), Ye B (2013), Cheng Q (2014), Saville MK (2004), Yamauchi T (2014), Jin M (2017)	15
RAB40A	2	ELOC	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ASB9	0	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kwon S (2010), Debrincat MA (2007), Debrincat MA (2007), Muniz JR (2013), Thomas JC (2013), Andresen CA (2014), Huttlin EL (2015), Huttlin EL (2017)	8
VCP	6	CUL5	1	affinity chromatography technology	Yu CC (2013)	1
PML	7	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bernardi R (2004), Bernardi R (2004), Zhu H (2003), Zhu H (2003), Kurki S (2003), Kurki S (2003), Wei X (2003), Wei X (2003), Wu Q (2009), Chu Y (2011), Yang Q (2013), Yang Q (2013), Bursac S (2012)	13
UBC	7	UBE2L3	1	affinity chromatography technology	Bish RA (2007)	1
ARIH2	4	NUBP1	0	biochemical	Kristensen AR (2012)	1
MDM2	2	ARIH2	4	affinity chromatography technology, affinity chromatography technology	Bae S (2012), Bae S (2012)	2
TRIM27	2	PML	7	affinity chromatography technology	Cao T (1998)	1
UBE2D1	0	MDM2	2	two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Singh RK (2007), Poyurovsky MV (2007), Li M (2003), Yogosawa S (2003), Honda R (1997), Sun XX (2011), Singh RK (2007), Taira N (2010), Fu X (2010), Wang KS (2011), Wang X (2004), Sehat B (2008), Wawrzynow B (2007), Burch L (2004), Frazier DP (2012), Huart AS (2012), Pettersson S (2009), Gama V (2009), Demma M (2010), Chymkowitch P (2011), Yan C (2010), Yang Y (2013), Ranaweera RS (2013), Siepe D (2009), Shi D (2009), Uchiki T (2009), Grossman SR (2003), Xirodimas DP (2004), Saville MK (2004), Liu T (2015), Batuello CN (2015), Fraser JA (2015), Yamauchi T (2014), Liu D (2016), McClurg UL (2016), Landre V (2017)	36
NEDD8	0	EEF1G	0	affinity chromatography technology	Bennett EJ (2010)	1
ARIH2	4	ARIH2	4	enzymatic study	Kelsall IR (2013)	1
UBE2V1	0	ARIH2	4	two hybrid	Markson G (2009)	1
APEX1	1	ELOC	0	biochemical	Kristensen AR (2012)	1
SOCS6	0	ELOC	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Krebs DL (2002), Zadjali F (2011), Huttlin EL (2015), Huttlin EL (2017)	4
UBC	7	PPP2R1A	8	affinity chromatography technology	Matsumoto M (2005)	1
MDM2	2	UBE2L3	1	pull down, pull down	Hampe C (2006), Yamauchi T (2014)	2
UBE2R2	2	UBC	7	two hybrid, enzymatic study	Vinayagam A (2011), Hill S (2016)	2
UBE2N	1	UBE2V1	0	biochemical, pull down, pull down, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, two hybrid, biochemical, pull down, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Deng L (2000), Deng L (2000), Zhang M (2005), Andersen PL (2005), Andersen PL (2005), Scheper J (2010), Scheper J (2010), Scheper J (2010), Wooff J (2004), Plans V (2006), Huen MS (2008), Huen MS (2008), Havugimana PC (2012), Bohgaki M (2008), Petroski MD (2007), Sawasaki T (2008), Wan C (2015), Chen J (2015), Boldt K (2016), Zhang Y (2018)	20
DLST	3	TP53	0	affinity chromatography technology	Malty RH (2017)	1
PPP2R1A	8	EEF1A1	0	affinity chromatography technology, affinity chromatography technology	Aranda-Orgilles B (2008), Aranda-Orgilles B (2008)	2
UBE2D1	0	UBE2D2	0	biochemical	Havugimana PC (2012)	1
NEDD8	0	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
ARIH2	4	TWF2	2	biochemical	Kristensen AR (2012)	1
TP53	0	APEX1	1	biochemical, affinity chromatography technology	Jayaraman L (1997), Seemann S (2005)	2
RAB40A	2	CUL5	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBE2D3	1	ARIH2	4	two hybrid	Markson G (2009)	1
BUB1	3	ARIH2	4	two hybrid	Rual JF (2005)	1
ARIH2	4	ARAP1	7	two hybrid	Stelzl U (2005)	1
NTRK1	1	VCP	6	affinity chromatography technology	Emdal KB (2015)	1
NUBP1	0	HK2	3	biochemical	Kristensen AR (2012)	1
REL	5	ARIH2	4	two hybrid	Rolland T (2014)	1
ARIH2	4	ENSA	0	two hybrid	Stelzl U (2005)	1
RAB40A	2	ARIH2	4	affinity chromatography technology	Huttlin EL (2015)	1
NEDD8	0	ARIH2	4	pull down	Kelsall IR (2013)	1
ARIH2	4	PML	7	affinity chromatography technology	Pietschmann K (2012)	1
TRIM27	2	TP53	0	affinity chromatography technology, pull down, enzymatic study	Chu Y (2011), Chu Y (2011), Chu Y (2011)	3
ARIH2	4	SCAMP2	3	two hybrid	Stelzl U (2005)	1
KAT5	1	NOTCH1	25	affinity chromatography technology, genetic interference, affinity chromatography technology	Kim MY (2007), Kim SY (2007), Kim SY (2007)	3
ARIH2	4	SLC1A6	0	two hybrid	Stelzl U (2005)	1
ARIH2	4	UBC	7	enzymatic study	Marteijn JA (2009)	1
CUL5	1	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D2	0	UBC	7	x-ray crystallography, x-ray crystallography, enzymatic study, pull down, pull down	Juang YC (2012), Dou H (2012), Sheng Y (2012), Buetow L (2015), Zhang X (2017)	5
UBE2L6	0	TRIM27	2	two hybrid	Markson G (2009)	1
TULP3	0	PML	7	affinity chromatography technology	Huttlin EL (2017)	1
PAPSS2	3	APEX1	1	biochemical	Kristensen AR (2012)	1
ARIH2	4	ELOC	0	affinity chromatography technology	Kelsall IR (2013)	1
ARIH2	4	GFI1	0	two hybrid, two hybrid, pull down, affinity chromatography technology	Marteijn JA (2007), Marteijn JA (2007), Marteijn JA (2007), Marteijn JA (2007)	4
SOCS6	0	UBE2D2	0	pull down	Zadjali F (2011)	1
PDLIM1	1	HK2	3	biochemical	Kristensen AR (2012)	1
EEF1A1	0	EEF1G	0	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	4
ARIH2	4	EEF1G	0	two hybrid	Stelzl U (2005)	1
VCP	6	MDM2	2	affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Okoro DR (2013)	2
UBE2D4	0	ARIH2	4	two hybrid	Markson G (2009)	1
DISC1	6	ARIH2	4	two hybrid	Camargo LM (2007)	1
NTRK1	1	ARAP1	7	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	EHD1	5	affinity chromatography technology	Emdal KB (2015)	1
MDM2	2	UBE2D2	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Iyappan S (2010), Dou H (2012), Brenkman AB (2008), Fang S (2000), Szypowska AA (2011), Okamoto K (2009), Busso CS (2009), Maguire M (2008), Sehat B (2008), Uldrijan S (2007), Yang Y (2005), Jin Y (2004), Roxburgh P (2012), Shloush J (2011), Rinaldo C (2007), Cheng Q (2009), Amson R (2011), Li X (2009), David Y (2011), Sosin AM (2012), Schumacher FR (2013), Bista M (2013), Mikawa T (2014), Lohrum MA (2001), Fang S (2001), Saville MK (2004), Rodriguez MS (1999), Auger KR (2005), Wu PY (2003), Wu H (2015), Yamauchi T (2014), Nomura K (2017), Kurokawa M (2013)	33
ARIH2	4	HK2	3	biochemical	Kristensen AR (2012)	1
UBC	7	TRIM27	2	affinity chromatography technology	Matsumoto M (2005)	1
MDM2	2	NOTCH1	25	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Lim SO (2011), Lim SO (2011), Pettersson S (2012), Pettersson S (2012), Pettersson S (2012)	5
SOCS6	0	ARIH2	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ARIH2	4	EML4	1	two hybrid	Stelzl U (2005)	1
ARIH2	4	KCNQ2	38	two hybrid	Stelzl U (2005)	1
APEX1	1	TWF2	2	biochemical	Kristensen AR (2012)	1
TRIM27	2	UBE2E1	1	two hybrid, two hybrid	Napolitano LM (2011), Napolitano LM (2011)	2
ARIH2	4	147791	0	two hybrid	Stelzl U (2005)	1
UBE2T	0	TRIM27	2	two hybrid	Markson G (2009)	1
UBE2E2	1	TRIM27	2	two hybrid	Napolitano LM (2011)	1