Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CACNG2 10369 BEPRIDIL HYDROCHLORIDE CHEMBL1200382 blocker ChemblInteractions
CACNG2 10369 LITHIUM CHEMBL2146126 PharmGKB
CACNG2 10369 PREGABALIN CHEMBL1059 modulator ChemblInteractions
CACNG2 10369 GABAPENTIN CHEMBL940 modulator ChemblInteractions
CACNG2 10369 IMAGABALIN CHEMBL2103836 modulator ChemblInteractions
CACNG2 10369 GABAPENTIN ENACARBIL CHEMBL1628502 modulator ChemblInteractions
CACNG2 10369 ATAGABALIN CHEMBL593430 modulator ChemblInteractions

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CACNG2 rs2284017 CC lithium efficacy not stated This is from a review article which does not give all the details. Genotype CC is associated with increased response to lithium in people with Bipolar Disorder. 21047205 699639151
CACNG2 rs2284017 C lithium efficacy not stated Allele C is associated with increased response to lithium in people with Bipolar Disorder as compared to allele T. 18408563 608431344
CACNG2 rs2284018 TT lithium efficacy yes This is significant in the second cohort listed but not in the first. Genotype TT is associated with decreased response to lithium in people with Bipolar Disorder as compared to genotypes CC + CT. 18408563 981419765