PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CDC5L	2	DDX6	0	affinity chromatography technology	Lleres D (2010)	1
YWHAZ	1	APP	1	pull down	Olah J (2011)	1
SRPK2	1	PAK4	3	enzymatic study	Varjosalo M (2013)	1
NTRK1	1	RCC2	0	affinity chromatography technology	Emdal KB (2015)	1
YWHAQ	0	YWHAG	5	affinity chromatography technology, biochemical	Pozuelo-Rubio M (2010), Kristensen AR (2012)	2
SFN	1	ABL1	9	affinity chromatography technology	Raina D (2006)	1
XPO1	8	YWHAG	5	affinity chromatography technology	Kirli K (2015)	1
G3BP1	4	YWHAQ	0	affinity chromatography technology	Jain S (2016)	1
ABL1	9	PAK4	3	biochemical	Wan C (2015)	1
ITGAV	7	PXN	1	affinity chromatography technology	Elsegood CL (2006)	1
PAK4	3	APP	1	pull down	Olah J (2011)	1
YWHAQ	0	VCL	6	biochemical	Kristensen AR (2012)	1
DLST	3	YWHAE	0	affinity chromatography technology	Malty RH (2017)	1
HECW2	13	SRPK1	2	affinity chromatography technology	Lu L (2013)	1
PAK4	3	PPM1B	2	biochemical	Wan C (2015)	1
PAK4	3	RAB3IP	0	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	KIF13B	13	affinity chromatography technology	Emdal KB (2015)	1
LIMK1	3	HIST1H1A	0	enzymatic study	Okano I (1995)	1
NTRK1	1	VCL	6	affinity chromatography technology	Emdal KB (2015)	1
PAK4	3	NAA25	4	biochemical	Wan C (2015)	1
FBXO25	1	EGFR	5	enzymatic study	Teixeira FR (2013)	1
XPO1	8	VCL	6	biochemical	Kristensen AR (2012)	1
PAK6	0	RAC1	7	affinity chromatography technology, pull down	Woolery AR (2014), Lee SR (2002)	2
CDC42	3	CDH1	4	pull down, affinity chromatography technology	Shen Y (2008), Shen Y (2008)	2
DLST	3	YWHAG	5	affinity chromatography technology	Malty RH (2017)	1
SNW1	0	PAK4	3	affinity chromatography technology	Lleres D (2010)	1
PPM1B	2	LRRK1	12	biochemical	Wan C (2015)	1
EGFR	5	YWHAB	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
NTRK1	1	G3BP1	4	affinity chromatography technology	Emdal KB (2015)	1
NAA25	4	NAA20	2	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
NTRK1	1	YWHAE	0	affinity chromatography technology	Emdal KB (2015)	1
ITGB3	6	ITGAV	7	x-ray crystallography, imaging technique, affinity chromatography technology	Xiong JP (2002), Moon HE (2015), Ward CM (2000)	3
PTPN7	3	APP	1	pull down	Olah J (2011)	1
PAK4	3	ITGAV	7	affinity chromatography technology	Kesanakurti D (2012)	1
CDH1	4	VCL	6	affinity chromatography technology, affinity chromatography technology, bioid	Hazan RB (1997), Hazan RB (1998), Guo Z (2014)	3
RCC2	0	RAC1	7	affinity chromatography technology	Williamson RC (2014)	1
PXN	1	ITGB3	6	pull down	Pfaff M (2001)	1
YWHAE	0	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
PAK4	3	CARMIL1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TMEM17	0	PAK4	3	bioid	Gupta GD (2015)	1
CDK6	0	CBY1	3	enzymatic study	Anders L (2011)	1
NAA25	4	APP	1	pull down	Olah J (2011)	1
YWHAG	5	TERF1	1	two hybrid, two hybrid	Bandyopadhyay S (2010), Lee OH (2011)	2
EGFR	5	G3BP1	4	affinity chromatography technology	Yao Z (2017)	1
ITGB5	3	PAK4	3	two hybrid, pull down, affinity chromatography technology	Zhang H (2002), Zhang H (2002), Zhang H (2002)	3
SNW1	0	CDC5L	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Wan C (2015), Lleres D (2010), Lleres D (2010)	4
NTRK1	1	SRPK2	1	affinity chromatography technology	Emdal KB (2015)	1
YWHAZ	1	ABL1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Raina D (2006), Yoshida K (2005), Yoshida K (2005), Yoshida K (2005), So J (2015)	5
RAN	1	XPO1	8	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, biochemical	Tickenbrock L (2002), Fornerod M (1997), Plafker K (2000), Chase GP (2011), Lipowsky G (2000), Havugimana PC (2012), von Knethen A (2010), Wan C (2015)	8
YWHAB	1	DDX6	0	affinity chromatography technology	Couzens AL (2013)	1
EGFR	5	PTPN7	3	two hybrid	Yao Z (2017)	1
MMP2	2	PAK4	3	affinity chromatography technology, affinity chromatography technology, pull down, genetic interference	Kesanakurti D (2012), Kesanakurti D (2012), Kesanakurti D (2012), Kesanakurti D (2012)	4
NTRK1	1	SRPK1	2	affinity chromatography technology	Emdal KB (2015)	1
PPM1B	2	CDK6	0	enzymatic study, biochemical	Cheng A (2000), Cheng A (2000)	2
PAK4	3	PAK4	3	enzymatic study	Dart AE (2015)	1
MMP2	2	ITGB3	6	affinity chromatography technology	Kesanakurti D (2012)	1
CDC5L	2	YWHAZ	1	two hybrid	Camargo LM (2007)	1
YWHAE	0	PAK4	3	affinity chromatography technology	Gloeckner CJ (2007)	1
CDH1	4	PAK6	0	bioid	Guo Z (2014)	1
XPO1	8	ABL1	9	unspecified method, unspecified method	Xu D (2012), Hantschel O (2005)	2
EGFR	5	YWHAZ	1	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2009), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
EGFR	5	SUPT5H	2	affinity chromatography technology	Yao Z (2017)	1
PAK4	3	RAC1	7	affinity chromatography technology	Dan C (2002)	1
TERF1	1	SUPT5H	2	two hybrid	Lee OH (2011)	1
NTRK1	1	XPO1	8	affinity chromatography technology	Emdal KB (2015)	1
RAB3IP	0	YWHAE	0	affinity chromatography technology	Boldt K (2016)	1
CDH1	4	RAN	1	bioid	Guo Z (2014)	1
YWHAB	1	YWHAZ	1	affinity chromatography technology, biochemical, affinity chromatography technology	Couzens AL (2013), Wan C (2015), Hein MY (2015)	3
RHOU	0	POT1	2	pull down	Dart AE (2015)	1
XPO1	8	DDX6	0	affinity chromatography technology	Kirli K (2015)	1
SFN	1	CBY1	3	affinity chromatography technology	Mancini M (2015)	1
CDH1	4	YWHAB	1	bioid	Guo Z (2014)	1
NTRK1	1	CDC5L	2	affinity chromatography technology	Emdal KB (2015)	1
YWHAB	1	YWHAG	5	affinity chromatography technology, biochemical	Couzens AL (2013), Wan C (2015)	2
PAK4	3	GGNBP2	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PAK4	3	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
YWHAZ	1	SFN	1	biochemical, affinity chromatography technology, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2015), Huttlin EL (2017)	3
PTPN4	0	YWHAE	0	affinity chromatography technology	Yadav L (2017)	1
EGFR	5	HECW2	13	affinity chromatography technology	Yao Z (2017)	1
YWHAG	5	PAK4	3	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Jin J (2004)	2
MTUS2	4	SH3RF2	0	two hybrid	Rolland T (2014)	1
PTPN4	0	YWHAB	1	affinity chromatography technology, affinity chromatography technology	Li X (2016), Yadav L (2017)	2
G3BP1	4	CDC5L	2	affinity chromatography technology	Jain S (2016)	1
YWHAG	5	SFN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Benzinger A (2005), Benzinger A (2005), Huttlin EL (2015), Huttlin EL (2017)	4
NTRK1	1	YWHAB	1	affinity chromatography technology	Emdal KB (2015)	1
YWHAG	5	CDC5L	2	affinity chromatography technology	Jin J (2004)	1
CDH1	4	PXN	1	bioid	Guo Z (2014)	1
CDC5L	2	PAK4	3	affinity chromatography technology	Lleres D (2010)	1
CDH1	4	CARMIL1	3	bioid	Guo Z (2014)	1
RAC1	7	SH3RF2	0	affinity chromatography technology	Wilhelm M (2012)	1
YWHAZ	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
YWHAB	1	ABL1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Raina D (2006), Yoshida K (2005), Yoshida K (2005), So J (2015)	4
RCC2	0	CDC42	3	affinity chromatography technology	Williamson RC (2014)	1
MMP2	2	ITGAV	7	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Kesanakurti D (2012), Kesanakurti D (2012), Kesanakurti D (2012), Kesanakurti D (2012)	4
PAK4	3	DLST	3	two hybrid	Stelzl U (2005)	1
EGFR	5	STYX	1	two hybrid	Yao Z (2017)	1
NTRK1	1	PAK4	3	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	PPM1A	1	affinity chromatography technology, two hybrid	Yao Z (2017), Yao Z (2017)	2
EGFR	5	PAK4	3	affinity chromatography technology	Yao Z (2017)	1
LRRK1	12	ABL1	9	affinity chromatography technology	Titz B (2010)	1
NTRK1	1	SNW1	0	affinity chromatography technology	Emdal KB (2015)	1
G3BP1	4	DDX6	0	affinity chromatography technology	Jain S (2016)	1
YWHAZ	1	YWHAG	5	biochemical, biochemical, affinity chromatography technology, fluorescent resonance energy transfe	Kristensen AR (2012), Wan C (2015), Hein MY (2015), Ivanov AA (2017)	4
DDX6	0	PAK4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
VCL	6	SFN	1	biochemical	Kristensen AR (2012)	1
SRPK1	2	LIMK1	3	enzymatic study	Varjosalo M (2013)	1
LRRK1	12	PAK4	3	affinity chromatography technology	Ewing RM (2007)	1
PAK4	3	PAK6	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
YWHAQ	0	SFN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pozuelo-Rubio M (2010), Huttlin EL (2015), Huttlin EL (2017)	3
SRPK2	1	ABL1	9	enzymatic study	Varjosalo M (2013)	1
NTRK1	1	YWHAZ	1	affinity chromatography technology	Emdal KB (2015)	1
PPM1A	1	PAK4	3	affinity chromatography technology	St-Denis N (2016)	1
CDC5L	2	YWHAQ	0	two hybrid	Camargo LM (2007)	1
SRPK1	2	PAK4	3	enzymatic study	Varjosalo M (2013)	1
YWHAE	0	YWHAQ	0	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Bandyopadhyay S (2010), Pozuelo-Rubio M (2010), Gloeckner CJ (2007), Wang J (2011)	4
RCC2	0	PAK4	3	affinity chromatography technology	Williamson RC (2014)	1
CDC42	3	ARHGEF11	8	two hybrid	Bandyopadhyay S (2010)	1
SFN	1	PAK4	3	affinity chromatography technology	Benzinger A (2005)	1
XPO1	8	KCTD3	2	affinity chromatography technology	Kirli K (2015)	1
PAK4	3	PAK5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NTRK1	1	RAN	1	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	YWHAQ	0	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
PAK6	0	YWHAE	0	affinity chromatography technology	Huttlin EL (2017)	1
ABL1	9	EGFR	5	unspecified method, two hybrid, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	3
PAK4	3	KLHL42	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PTPN4	0	YWHAG	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Li X (2016), Yadav L (2017)	3
XPO1	8	PAK4	3	affinity chromatography technology	Kirli K (2015)	1
G3BP1	4	APP	1	pull down	Olah J (2011)	1
PAK4	3	KCTD3	2	affinity chromatography technology	Boldt K (2016)	1
PAK5	0	RAC1	7	affinity chromatography technology	Dan C (2002)	1
TERF1	1	PAK4	3	two hybrid	Lee OH (2011)	1
YWHAQ	0	ABL1	9	unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu C (2012), Raina D (2006), Yoshida K (2005), Yoshida K (2005), So J (2015)	5
XPO1	8	PPM1B	2	affinity chromatography technology	Kirli K (2015)	1
PAK4	3	ITGB3	6	affinity chromatography technology	Kesanakurti D (2012)	1
PTPN4	0	YWHAQ	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Li X (2016), Yadav L (2017)	3
CDK6	0	HIST1H1A	0	enzymatic study, enzymatic study	Jiang W (1998), Iyer NG (2007)	2
POT1	2	PAK4	3	two hybrid	Lee OH (2011)	1
PAK5	0	CDC42	3	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Dan C (2002), Pandey A (2002), Pandey A (2002), Bandyopadhyay S (2010)	4
PAK4	3	CDC42	3	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, biochemical, affinity chromatography technology	Ewing RM (2007), Dan C (2002), Abo A (1998), Bandyopadhyay S (2010), Wan C (2015), Dart AE (2015)	6
TMPRSS11A	1	PAK4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NTRK1	1	NAA25	4	affinity chromatography technology	Emdal KB (2015)	1
YWHAQ	0	PAK4	3	affinity chromatography technology, pull down	Ewing RM (2007), Meek SE (2004)	2
YWHAE	0	PPM1B	2	affinity chromatography technology, affinity chromatography technology	Zuo S (2010), Zuo S (2010)	2
TERF1	1	ABL1	9	affinity chromatography technology, affinity chromatography technology	Kishi S (2001), Kishi S (2001)	2
CDH1	4	EGFR	5	affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, bioid	Pece S (2000), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Li J (2013), Guo Z (2014)	6
KCTD3	2	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
PAK4	3	PXN	1	affinity chromatography technology	Dart AE (2015)	1
PTPN4	0	PAK4	3	affinity chromatography technology	St-Denis N (2016)	1
ABL1	9	LATS2	1	affinity chromatography technology, enzymatic study	Reuven N (2013), Reuven N (2013)	2
PAK6	0	YWHAZ	1	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	EGFR	5	affinity chromatography technology	Emdal KB (2015)	1
ITGAV	7	ITGB5	3	affinity chromatography technology	Avraham HK (2003)	1
G3BP1	4	RCC2	0	affinity chromatography technology	Jain S (2016)	1
EGFR	5	APP	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
YWHAE	0	YWHAB	1	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical	Bandyopadhyay S (2010), Gloeckner CJ (2007), Couzens AL (2013), Wan C (2015)	4
NTRK1	1	ARHGEF11	8	affinity chromatography technology	Emdal KB (2015)	1
LIMK1	3	PAK4	3	pull down, enzymatic study	Dan C (2001), Dan C (2001)	2
PAK4	3	CDK6	0	affinity chromatography technology	Huttlin EL (2017)	1
PTPN7	3	PAK4	3	affinity chromatography technology	St-Denis N (2016)	1
PAK5	0	CARMIL1	3	affinity chromatography technology	Huttlin EL (2017)	1
PAK5	0	SUPT5H	2	affinity chromatography technology	Huttlin EL (2017)	1
DLST	3	YWHAZ	1	affinity chromatography technology	Malty RH (2017)	1
PAK6	0	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
YWHAB	1	PAK4	3	affinity chromatography technology	Couzens AL (2013)	1
PAK6	0	YWHAG	5	affinity chromatography technology	Huttlin EL (2017)	1
G3BP1	4	YWHAB	1	affinity chromatography technology	Jain S (2016)	1
RHOU	0	PXN	1	pull down	Dart AE (2015)	1
SRPK2	1	TMPRSS11A	1	enzymatic study	Lipp JJ (2015)	1
NTRK1	1	SUPT5H	2	affinity chromatography technology	Emdal KB (2015)	1
YWHAB	1	APP	1	pull down	Olah J (2011)	1
NTRK1	1	YWHAG	5	affinity chromatography technology	Emdal KB (2015)	1
STYX	1	PAK4	3	affinity chromatography technology	St-Denis N (2016)	1
EGFR	5	XPO1	8	affinity chromatography technology	Foerster S (2013)	1
NTRK1	1	ABL1	9	two hybrid, affinity chromatography technology, pull down	Koch A (2000), Yano H (2000), Koch A (2000)	3
EGFR	5	LRRK1	12	affinity chromatography technology	Yao Z (2017)	1
NTRK1	1	CDK6	0	affinity chromatography technology	Emdal KB (2015)	1
CDH1	4	YWHAE	0	bioid	Guo Z (2014)	1
YWHAQ	0	YWHAZ	1	affinity chromatography technology, biochemical, affinity chromatography technology	Pozuelo-Rubio M (2010), Kristensen AR (2012), Hein MY (2015)	3
APP	1	YWHAG	5	two hybrid, affinity chromatography technology, unspecified method	Sumioka A (2005), Sumioka A (2005), Sumioka A (2005)	3
PAK4	3	HIST1H1A	0	enzymatic study	Dart AE (2015)	1
SFN	1	RAB3IP	0	two hybrid	Rolland T (2014)	1
PAK4	3	RHOV	1	affinity chromatography technology	Dart AE (2015)	1
PAK4	3	ARHGEF11	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGFR	5	PPM1B	2	two hybrid	Yao Z (2017)	1
LATS2	1	YWHAG	5	affinity chromatography technology, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe	Okada N (2011), Okada N (2011), Okada N (2011), Ivanov AA (2017)	4
YWHAZ	1	LIMK1	3	two hybrid, pull down	Birkenfeld J (2003), Birkenfeld J (2003)	2
FBXO25	1	XPO1	8	affinity chromatography technology	Teixeira FR (2010)	1
KIF13B	13	YWHAB	1	affinity chromatography technology	Yoshimura Y (2010)	1
SRPK2	1	APP	1	pull down	Olah J (2011)	1
HECW2	13	PAK4	3	affinity chromatography technology	Lu L (2013)	1
YWHAZ	1	YWHAE	0	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, biochemical, biochemical, affinity chromatography technology, pull down	Bandyopadhyay S (2010), Zippo A (2009), Zippo A (2009), Havugimana PC (2012), Gloeckner CJ (2007), Wang J (2011), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Gu YM (2006)	10
PAK4	3	NAA20	2	biochemical	Wan C (2015)	1
YWHAZ	1	XPO1	8	affinity chromatography technology	Hein MY (2015)	1
SFN	1	G3BP1	4	affinity chromatography technology, affinity chromatography technology	Wilker EW (2007), Jain S (2016)	2
EGFR	5	RCC2	0	affinity chromatography technology	Yao Z (2017)	1
PAK4	3	VCL	6	affinity chromatography technology	Dart AE (2015)	1
SRPK1	2	SRPK2	1	biochemical	Edmond V (2011)	1
FBXO25	1	PAK4	3	enzymatic study	Teixeira FR (2013)	1
EGFR	5	SFN	1	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Wu SL (2006), Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Li J (2013)	5
PPM1A	1	PPM1B	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
G3BP1	4	PAK4	3	affinity chromatography technology	Jain S (2016)	1
POT1	2	TERF1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Loayza D (2003), Giannone RJ (2010), Giannone RJ (2010), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
PAK4	3	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
YWHAQ	0	DDX6	0	affinity chromatography technology	Ewing RM (2007)	1
TERF1	1	XPO1	8	affinity chromatography technology	Hein MY (2015)	1
PAK5	0	ARHGEF11	8	affinity chromatography technology	Huttlin EL (2017)	1
PAK4	3	SUPT5H	2	affinity chromatography technology	Huttlin EL (2015)	1
PAK5	0	YWHAZ	1	affinity chromatography technology	Huttlin EL (2017)	1
YWHAG	5	ABL1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Raina D (2006), Yoshida K (2005), Yoshida K (2005), So J (2015)	4
CDH1	4	YWHAZ	1	bioid	Guo Z (2014)	1
ABL1	9	NAA25	4	biochemical	Wan C (2015)	1
LIMK1	3	APP	1	pull down	Olah J (2011)	1
SH3RF2	0	DDX6	0	affinity chromatography technology	Kim TW (2013)	1
XPO1	8	PXN	1	unspecified method, affinity chromatography technology	Xu D (2012), Kirli K (2015)	2
SRPK1	2	APP	1	pull down	Olah J (2011)	1
NTRK1	1	YWHAQ	0	affinity chromatography technology	Emdal KB (2015)	1
SH3RF2	0	G3BP1	4	affinity chromatography technology	Kim TW (2013)	1
NTRK1	1	SFN	1	affinity chromatography technology	Emdal KB (2015)	1
SH3RF2	0	APP	1	pull down	Olah J (2011)	1
CDH1	4	DDX6	0	bioid	Guo Z (2014)	1
PAK4	3	RHOU	0	affinity chromatography technology, pull down, pull down	Dart AE (2015), Dart AE (2015), Dart AE (2015)	3
YWHAQ	0	YWHAB	1	affinity chromatography technology, affinity chromatography technology, biochemical	Pozuelo-Rubio M (2010), Couzens AL (2013), Kristensen AR (2012)	3
CDC5L	2	YWHAE	0	affinity chromatography technology	Lleres D (2010)	1
FBXO25	1	G3BP1	4	enzymatic study	Teixeira FR (2013)	1
YWHAE	0	ABL1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Raina D (2006), Yoshida K (2005), Yoshida K (2005), So J (2015)	4
SRPK2	1	DDX6	0	enzymatic study	Varjosalo M (2013)	1
PAK4	3	RAN	1	enzymatic study	Bompard G (2010)	1
CDK6	0	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KCTD3	2	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
SRPK2	1	YWHAB	1	enzymatic study, affinity chromatography technology	Varjosalo M (2013), Jang SW (2009)	2
CDC42	3	PAK6	0	pull down, two hybrid	Lee SR (2002), Bandyopadhyay S (2010)	2
CDH1	4	SFN	1	bioid	Guo Z (2014)	1
DLST	3	YWHAQ	0	affinity chromatography technology	Malty RH (2017)	1
PTPN4	0	YWHAZ	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Li X (2016), Yadav L (2017)	3
YWHAE	0	XPO1	8	biochemical	Kristensen AR (2012)	1
POT1	2	YWHAE	0	two hybrid	Lee OH (2011)	1
RAN	1	ABL1	9	affinity chromatography technology	Daniel R (2001)	1
EGFR	5	CBY1	3	affinity chromatography technology	Yao Z (2017)	1
YWHAE	0	VCL	6	biochemical	Kristensen AR (2012)	1
ABL1	9	PPM1B	2	biochemical	Wan C (2015)	1
NTRK1	1	DDX6	0	affinity chromatography technology	Emdal KB (2015)	1
YWHAZ	1	VCL	6	biochemical	Kristensen AR (2012)	1
LATS2	1	PAK4	3	bioid	Couzens AL (2013)	1
PXN	1	VCL	6	pull down, pull down, pull down, biochemical	Turner CE (1999), Mazaki Y (1997), Brown MC (1996), Wan C (2015)	4
YWHAG	5	YWHAE	0	two hybrid, affinity chromatography technology, two hybrid, biochemical	Bandyopadhyay S (2010), Gloeckner CJ (2007), Wang J (2011), Wan C (2015)	4
YWHAQ	0	PAK6	0	affinity chromatography technology	Ewing RM (2007)	1
SFN	1	YWHAB	1	affinity chromatography technology	Huttlin EL (2017)	1
MTUS2	4	PAK4	3	affinity chromatography technology	Huttlin EL (2017)	1
RAB3IP	0	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
ITGB5	3	MTUS2	4	two hybrid	Rolland T (2014)	1
CBY1	3	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
YWHAG	5	VCL	6	biochemical	Kristensen AR (2012)	1
POT1	2	YWHAG	5	two hybrid	Lee OH (2011)	1
CDH1	4	PAK4	3	bioid	Guo Z (2014)	1
TERF1	1	HIST1H1A	0	two hybrid	Lee OH (2011)	1
YWHAZ	1	PAK4	3	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Jin J (2004)	2
SH3RF2	0	PAK4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kim TW (2013), Kim TW (2013), Kim TW (2013), Kim TW (2013)	4
NTRK1	1	ITGAV	7	affinity chromatography technology	Emdal KB (2015)	1
SNW1	0	MTUS2	4	two hybrid	Rolland T (2014)	1
HECW2	13	SNW1	0	affinity chromatography technology	Lu L (2013)	1