PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TK1	0	CDKN1A	1	affinity chromatography technology, pull down	Huang DY (2001), Huang DY (2001)	2
CCND3	1	CDK4	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Arsenijevic T (2004), Lin J (2001), Zhang Q (1999), Datta NS (1998), Garcia-Morales P (2006), Bockstaele L (2006), Ramachandran N (2004), Wang J (2011), Lodewick J (2013), Rolland T (2014), Huttlin EL (2015), Yu H (2011), Hein MY (2015), Huttlin EL (2017)	15
CCNE1	1	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Harbour JW (1999), Manenti S (1999), Horton LE (1997), Higashi H (1996), Jiang W (1998), Connell-Crowley L (1997), Gaiddon C (2003), Zarkowska T (1997), Nakanishi M (1999)	9
LRR1	1	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Starostina NG (2010), Starostina NG (2010), Starostina NG (2010)	3
CDK2	0	PARP1	3	affinity chromatography technology	Neganova I (2011)	1
CCNA2	1	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ESR1	0	TUBA1A	13	affinity chromatography technology	Azuma K (2004)	1
CDK2	0	SET	8	affinity chromatography technology	Neganova I (2011)	1
CDKN1A	1	HDAC1	4	pull down, affinity chromatography technology, pull down, imaging technique	Li Z (2010), Li Z (2010), Garcia-Wilson E (2005), Chen TC (2014)	4
MDM4	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Jin Y (2008), Jin Y (2008), Jin Y (2008), Jin Y (2008), Jin Y (2008), Lee JH (2011), Lee JH (2011)	7
PIM1	2	MDM2	2	enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Wood NT (2009), Hogan C (2008), Hogan C (2008), Hogan C (2008), Hogan C (2008)	5
CUL2	3	NPM1	0	affinity chromatography technology	Bennett EJ (2010)	1
RB1	2	KAT2B	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Nguyen DX (2004), Nguyen DX (2004), Nguyen DX (2004), Ianari A (2009)	4
MDM2	2	CCND1	1	affinity chromatography technology	Yang P (2016)	1
CDKN1A	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology	Ono T (2000), McKenzie PP (2003), McKenzie PP (2003), Law BK (2002), Harper JW (1993), Harper JW (1993), Yam CH (1999), Selma Dagtas A (2010), Naderi S (2005), Varshochi R (2005), Jeong JH (2010), Hsu SP (2008), Scholz A (2003), Peiretti A (2003), Peiretti A (2003), Derjuga A (2001), Kim YB (2000), Park US (2000), Kim WH (2000), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bendjennat M (2003), Zheleva DI (2002), Mandal M (1998), Bao GC (2006), Mattock H (2001), Chen Z (2002), Chen J (1996), Chen J (1996), Levkau B (1998), Levkau B (1998), Ramachandran N (2004), Lacy ER (2005), Akagi M (1996), Zhao J (1998), Zhang Y (1999), Poon RY (1998), Gorospe M (1996), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Hall JR (2014), Hein MY (2015), Hein MY (2015), Chen TC (2014), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	51
CEBPA	0	CDK2	0	biochemical, affinity chromatography technology, pull down, affinity chromatography technology	Wang H (2001), Wang H (2001), Wang H (2001), Wang GL (2004)	4
CEBPA	0	CDK4	2	biochemical, affinity chromatography technology, pull down, biochemical, affinity chromatography technology	Wang H (2001), Wang H (2001), Wang H (2001), Wang H (2002), Wang GL (2004)	5
CDK6	0	PSMA3	1	two hybrid	Rolland T (2014)	1
MDM2	2	SET	8	pull down	Miyamoto-Sato E (2010)	1
CCNE1	1	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Shanahan F (1999), Connor MK (2003), Connor MK (2003), Jeon Y (2007), Bustany S (2011), Xu X (1999), Xu X (1999), Datta NS (1998), Orend G (1998), Liu J (1997), Sheaff RJ (1997), Sheaff RJ (1997), Bresnahan WA (1996), Vlach J (1996), Vlach J (1997), Ciarallo S (2002), Ciarallo S (2002), Ciarallo S (2002), Chu I (2007), Chu I (2007), Chen J (1996), Levkau B (1998), Larrea MD (2009), Grimmler M (2007), Chen TC (2014), Qiu H (2016)	26
CDKN1A	1	MAPK8	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Selma Dagtas A (2010), Selma Dagtas A (2010), Kim GY (2002)	3
EP300	36	CDK1	0	affinity chromatography technology, enzymatic study	Wang SA (2014), Wang SA (2014)	2
MDM2	2	DAPK3	5	unspecified method, enzymatic study, imaging technique	Burch LR (2004), Burch LR (2004), Felten A (2012)	3
CCNE2	2	CDKN1B	1	affinity chromatography technology, two hybrid, affinity chromatography technology	Lauper N (1998), Zariwala M (1998), Zariwala M (1998)	3
MDM2	2	KAT2B	2	pull down, affinity chromatography technology, genetic interference, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Jin Y (2002), Jin Y (2002), Jin Y (2002), Jin Y (2004), Jin Y (2004), Jung CR (2010), Morgan JE (2017)	7
TSG101	1	RNF126	2	two hybrid	Markson G (2009)	1
CCNB1	3	CDC6	0	enzymatic study	Jiang W (1999)	1
CUL4A	2	MDM2	2	affinity chromatography technology, affinity chromatography technology	Banks D (2006), Latini P (2011)	2
STAT3	0	RB1	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Barre B (2005), Barre B (2005), Barre B (2005), Barre B (2005)	4
CDKN1A	1	TEX11	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
HDAC1	4	ESR1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique	Kawai H (2003), Kawai H (2003), Varshochi R (2005), Varshochi R (2005), Kurtev V (2004), Liu XF (2004), Itoh Y (2007), Tarallo R (2011), Yoshimaru T (2013)	9
CCNB1	3	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Di Fiore B (2010), Nishiyama A (2000), Wolthuis R (2008), Desai D (1995), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	11
CDK4	2	CDK6	0	affinity chromatography technology, fluorescent resonance energy transfe	Varjosalo M (2013), Ivanov AA (2017)	2
PCNA	0	CDK5	0	affinity chromatography technology, affinity chromatography technology	Takasaki Y (2001), Wu SM (1998)	2
CDK4	2	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Lin J (2001), Kehn K (2004), Kehn K (2004), Sweeney KJ (1997), Huttlin EL (2015), Huttlin EL (2017), Denicourt C (2008), Ivanov AA (2017)	8
PSMA3	1	CDKN1A	1	pull down, affinity chromatography technology, pull down, pull down	Touitou R (2001), Wang B (2010), Wang B (2010), Xu H (2010)	4
CDK2	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Youn CK (2005), Porter LA (2003), Law BK (2002), Connor MK (2003), Naderi S (2005), Varshochi R (2005), Hsu SP (2008), McAndrew CW (2007), Peiretti A (2003), Peiretti A (2003), Haddad MM (1999), Xu X (1999), Xu X (1999), Radu M (2008), Mori S (1999), Schulman BA (1998), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Sheaff RJ (1997), Vlach J (1996), Vlach J (1996), Vlach J (1997), Liu S (2009), Rosner M (2004), Ciarallo S (2002), Ciarallo S (2002), Wang Y (2008), Bockstaele L (2006), Chu I (2007), Chu I (2007), Levkau B (1998), Levkau B (1998), Lacy ER (2005), Zhao J (1998), Seo DW (2006), Kossatz U (2006), Grimmler M (2007), Grimmler M (2007), Varjosalo M (2013), Varjosalo M (2013), Montagnoli A (1999), So J (2015), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Lovisa S (2016), Qiu H (2016), Carrasco-Garcia E (2011), Huttlin EL (2017), Hu B (2017)	52
CUL4A	2	TP53	0	affinity chromatography technology	Banks D (2006)	1
CCNB1	3	EP300	36	pull down, affinity chromatography technology	Felzien LK (1998), Felzien LK (1998)	2
EP300	36	PARP1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Messner S (2009), Hassa PO (2005), Hassa PO (2005), Hassa PO (2005), Hassa PO (2008), Hassa PO (2008), Hassa PO (2003), Hassa PO (2003), Hassa PO (2003), Kim BK (2014), Kim BK (2014)	11
PSMA3	1	YWHAQ	0	pull down, affinity chromatography technology	Wang B (2010), Wang B (2010)	2
CDC20	1	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005), Townsend K (2009)	3
CDKN1A	1	CCNA1	3	affinity chromatography technology, pull down, affinity chromatography technology, pull down, imaging technique	Zheleva DI (2002), Ramachandran N (2004), Rohaly G (2005), Heron-Milhavet L (2006), Chen TC (2014)	5
GAPDH	0	NPM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee SB (2012), Lee SB (2012), Chen R (2013)	3
CCNE1	1	SKP2	2	pull down, enzymatic study	Yeh KH (2001), Enchev RI (2012)	2
AKT1	1	CREBBP	29	pull down, enzymatic study	Drendall CI (2010), Drendall CI (2010)	2
TP53	0	NPM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dhar SK (2006), Kurki S (2004), Kurki S (2004), Lambert B (2006), Colombo E (2002), Colombo E (2002), Colombo E (2002), Fogeron ML (2013), Li J (2005)	9
CDKN1A	1	YWHAQ	0	affinity chromatography technology, affinity chromatography technology, pull down	Wang B (2010), Wang B (2010), Wang B (2010)	3
GAPDH	0	EP300	36	affinity chromatography technology, affinity chromatography technology	Sen N (2008), Sen N (2008)	2
MAPK14	0	KAT2B	2	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Pillai VB (2011), Pillai VB (2011), Pillai VB (2011), Pillai VB (2011)	4
CCNA1	3	CDK2	0	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, imaging technique	Sweeney C (1996), Yang R (1997), Yang R (1997), Mueller-Tidow C (2001), Brown NR (1999), Niida H (2005), Yam CH (2000), Wang H (2009), Narayanan R (2005), Harwell RM (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Peiretti A (2003), Pan ZQ (1993), Kim KS (2002), Lyapina SA (1998), Desai D (1995), Thomas DM (2004), Johnson LN (2002), Rohaly G (2005), Chen TC (2014)	22
CDKN1A	1	CDK4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Selma Dagtas A (2010), Guidoboni M (2005), Santiago FS (2007), Santiago FS (2007), Hsu SP (2008), Kehn K (2004), Kokontis JM (1998), Orend G (1998), Zheleva DI (2002), Mandal M (1998), Chen J (1996), Chen J (1996), Ramachandran N (2004), Gorospe M (1996), Fogeron ML (2013), Hukkelhoven E (2012), Hukkelhoven E (2012), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	20
SKP2	2	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique	Amador V (2007), Hwang CY (2007), Calvisi DF (2009), Bendjennat M (2003), Wu L (2012), Wu L (2012), Abbas T (2008), Ungermannova D (2005), Chen TC (2014)	9
MAPK14	0	RB1	2	enzymatic study, affinity chromatography technology	Delston RB (2011), Li H (2001)	2
GADD45A	1	ESR1	0	affinity chromatography technology	Yi YW (2000)	1
YWHAQ	0	GAPDH	0	pull down	Meek SE (2004)	1
ESR1	0	GAPDH	0	affinity chromatography technology	Tarallo R (2011)	1
EP300	36	ESR1	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, affinity chromatography technology, enzymatic study, pull down, pull down	Fajas L (2002), Fan S (2002), Fan S (2002), Fan S (2002), Kang YK (2002), Kang YK (2002), Hao L (2010), Jin W (2008), Cui Y (2006), Dutertre M (2003), Dutertre M (2003), Shiozawa T (2003), Kim SH (2010), Ma Y (2010), Ma Y (2010), Fujita T (2003), Likhite VS (2004), Band AM (2011), Loven MA (2004), Nalvarte I (2010), Yi P (2015)	21
CCND2	2	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sweeney KJ (1997), Huttlin EL (2015), Huttlin EL (2017)	3
KAT2B	2	AKT1	1	enzymatic study, affinity chromatography technology	Sundaresan NR (2011), Sundaresan NR (2011)	2
CCNA2	1	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Higashi H (1996), Knudsen ES (1996), Jiang W (1998), Connell-Crowley L (1997), Gaiddon C (2003), Nakanishi M (1999)	7
SKP2	2	CCNB1	3	affinity chromatography technology	Bashir T (2010)	1
CUL4A	2	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Bennett EJ (2010), Sertic S (2013), Rossi M (2013), Jin J (2006), Shibata E (2011), Higa LA (2006)	7
CEBPA	0	RB1	2	affinity chromatography technology, affinity chromatography technology	Bararia D (2008), Wang GL (2004)	2
CDK3	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
AKT1	1	ESR1	0	enzymatic study	Campbell RA (2001)	1
CDK5	0	BAG6	2	two hybrid	Vinayagam A (2011)	1
CUL2	3	YWHAQ	0	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Craney A (2016), Huttlin EL (2017)	4
CCNB1	3	CDKN1A	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Amador V (2007), Garcia-Wilson E (2005), Ando T (2001), Poon RY (1996), Fogeron ML (2013), Chen TC (2014)	6
NPM1	0	PARP1	3	affinity chromatography technology	Haindl M (2008)	1
CCNB1	3	PCNA	0	affinity chromatography technology, affinity chromatography technology	Zhang H (1993), Huttlin EL (2017)	2
GADD45A	1	STAT3	0	affinity chromatography technology	Yang F (2013)	1
SKP2	2	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Wang W (2003), Sitry D (2002), Fujita N (2002), Ji P (2006), Zancai P (2005), Ji P (2004), Iovine B (2011), Calvisi DF (2009), Spruck C (2001), Bashir T (2010), Bashir T (2010), Li P (2004), Boutonnet C (2010), Rosner M (2004), Rosner M (2004), Carrano AC (1999), Carrano AC (1999), Carrano AC (1999), Wu J (2012), Strohmaier H (2001), Rodier G (2008), Rodier G (2008), Ooi LC (2013), Yumimoto K (2013), Ooi LC (2013), Cen B (2010), Enchev RI (2012), Yumimoto K (2012), Shi P (2011), Lovisa S (2016), Cen B (2009), Chan CH (2013), Ma X (2017)	33
ESR1	0	FKBPL	1	affinity chromatography technology, affinity chromatography technology	Donley C (2013), Donley C (2013)	2
PSME3	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen X (2007), Chen X (2007), Wu Y (2011)	3
CREBBP	29	PSME3	0	enzymatic study	Liu J (2013)	1
CCND1	1	STAT3	0	affinity chromatography technology, pull down, affinity chromatography technology	Bienvenu F (2001), Bienvenu F (2005), Bienvenu F (2005)	3
CDK3	0	CCNE1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
EP300	36	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Han Y (2008), Mayanil CS (2006), Simone C (2004), Simone C (2004), Simone C (2004), Liu Y (2012), Mizuguchi Y (2012)	7
CDK6	0	CCND1	1	pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology	Sugimoto M (1999), Lin J (2001), Sweeney KJ (1997), Ruas M (2007), Shu F (2007), Ramachandran N (2004), Ghiani C (2001)	7
KAT2B	2	CCND1	1	affinity chromatography technology	McMahon C (1999)	1
NPM1	0	PSME3	0	affinity chromatography technology	Chen R (2013)	1
MDM4	0	YWHAQ	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lopez-Pajares V (2008), Lopez-Pajares V (2008), Gilkes DM (2006)	3
CCNE2	2	CDK2	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gudas JM (1999), Lauper N (1998), Zariwala M (1998), Zariwala M (1998), Ramachandran N (2004), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	11
CDKN1B	1	YWHAQ	0	affinity chromatography technology, affinity chromatography technology	Fujita N (2002), Rosner M (2007)	2
CDK1	0	MDM4	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Elias B (2005), Elias B (2005), Elias B (2005)	3
RB1	2	CCNA1	3	pull down, affinity chromatography technology, enzymatic study	Yang R (1999), Yang R (1999), Zarkowska T (1997)	3
ESR1	0	STUB1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Fan M (2005), Tateishi Y (2004), Tateishi Y (2004), Tateishi Y (2004), Berry NB (2008), Dhamad AE (2016)	6
MDM4	0	EP300	36	pull down	Kadakia M (2002)	1
STUB1	4	PSMA3	1	affinity chromatography technology, affinity chromatography technology	Arndt V (2005), Meacham GC (2001)	2
MAPK14	0	HDAC1	4	biochemical	Wan C (2015)	1
CDK1	0	CDK3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CASP3	0	MAPK8	3	enzymatic study	Enomoto A (2003)	1
CDK2	0	CASP3	0	affinity chromatography technology	Neganova I (2011)	1
CDC6	0	CDK2	0	affinity chromatography technology, enzymatic study	Saha P (1998), Jiang W (1999)	2
CDKN1B	1	CCNA1	3	pull down, affinity chromatography technology	Ji P (2006), Thomas DM (2004)	2
EP300	36	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kitagawa M (2008), Inuzuka H (2012), Inuzuka H (2012), Oh M (2016)	4
CDK2	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Shintani S (2000), Nair JS (2009), Takaki T (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Harbour JW (1999), Horton LE (1997), Higashi H (1996), Delston RB (2011), Kim KS (2002), Chen W (2004), Liberal V (2012), Boyer Arnold N (2005), Dynlacht BD (1997), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Hara E (1997), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Gaiddon C (2003), Seo DW (2006), Zarkowska T (1997), Grimmler M (2007), Nakanishi M (1999), Pevarello P (2005), Iyer NG (2007), Chan HM (2001), Pan W (2001)	32
STUB1	4	PARP1	3	affinity chromatography technology, affinity chromatography technology	Choi JR (2016), Choi JR (2016)	2
CDK2	0	PSMD2	2	affinity chromatography technology	Neganova I (2011)	1
CCND1	1	CDK5	0	affinity chromatography technology	Huttlin EL (2017)	1
CDK4	2	CDC6	0	enzymatic study	Anders L (2011)	1
TSG101	1	EP300	36	affinity chromatography technology, pull down	Sun Z (1999), Sun Z (1999)	2
CDKN1A	1	CDK5	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lacy ER (2005), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013)	4
GADD45G	0	CDKN1A	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Azam N (2001), Azam N (2001), Azam N (2001), Nakayama K (1999)	4
PSME3	0	TP53	0	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology	Zhang Z (2008), Zhang Z (2008), Zhang Z (2008), Liu J (2010), Liu J (2010)	5
CDC20	1	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005), Huttlin EL (2017)	3
CASP3	0	PARP1	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Nicholson DW (1995), Lueschen S (1998), Walsh JG (2008), Boucher D (2012), Luo S (2010), Betin VM (2009)	6
EP300	36	KAT2B	2	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Kim JH (2011), Lee M (2010), Santos-Rosa H (2003), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996), Mizuguchi Y (2012)	8
DDB1	6	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Ji Q (2014), Ji Q (2014), Zhao R (2014), Romani B (2016)	4
CREBBP	29	MDM2	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Inoue Y (2011), Wang X (2004), Sanchez M (2012)	3
GADD45A	1	CCNB1	3	pull down	Vairapandi M (2002)	1
MDM4	0	MDM2	2	pull down, two hybrid, enzymatic study, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique, two hybrid, affinity chromatography technology, enzymatic study, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, two hybrid, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, pull down, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Kadakia M (2002), Tanimura S (1999), Badciong JC (2002), Tanimura S (1999), Tanimura S (1999), Linke K (2008), Okamoto K (2005), Pan Y (2003), Kashuba E (2011), Kashuba E (2011), Ohtsubo C (2009), Singh RK (2007), Zhu Y (2009), Zhu Y (2009), Allende-Vega N (2010), Okamoto K (2009), Okamoto K (2009), Li X (2011), Nie J (2010), Nie J (2010), Li M (2011), Li M (2011), Singh RK (2007), de Graaf P (2003), Wade M (2012), Uldrijan S (2007), Wade M (2012), Stad R (2000), Dolezelova P (2012), Kulikov R (2005), Kawai H (2007), Kawai H (2007), Miller KR (2010), Sharp DA (1999), Sharp DA (1999), Sharp DA (1999), Sharp DA (1999), Sharp DA (1999), Li C (2002), Wu S (2012), Ranaweera RS (2013), Woodsmith J (2012), Wang J (2011), Egorova O (2014), Chang YS (2013), Malbert-Colas L (2014), Yasuhara T (2014), Yasuhara T (2014), Iyappan S (2010), Stad R (2001), Marcar L (2015), Ling X (2014), Leslie PL (2015), Jacob AG (2014), Jacob AG (2014), Tournillon AS (2015), Tournillon AS (2015), Tournillon AS (2015), Zhang H (2015), Chen L (2015), Pellegrino M (2015), Pellegrino M (2015), Pellegrino M (2015), Medina-Medina I (2016), Medina-Medina I (2016), Moscetti I (2016), Liu T (2017), Liu T (2017), Liu T (2017), Huttlin EL (2017), Wu W (2015), Ivanov AA (2017), Mancini F (2016), Mancini F (2016)	74
JUN	0	TSG101	1	two hybrid, affinity chromatography technology	Camus G (2007), Camus G (2007)	2
CCNE1	1	CDK4	2	affinity chromatography technology, fluorescent resonance energy transfe	Datta NS (1998), Ivanov AA (2017)	2
YWHAQ	0	NPM1	0	affinity chromatography technology, pull down, affinity chromatography technology, biochemical	Pozuelo-Rubio M (2010), Meek SE (2004), Pozuelo-Rubio M (2010), Pozuelo-Rubio M (2010)	4
CDC20	1	PCNA	0	affinity chromatography technology	Craney A (2016)	1
CDKN1B	1	CDK6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Lin J (2001), Radu M (2008), Bockstaele L (2006), Chen TC (2014), Carrasco-Garcia E (2011), Huttlin EL (2017)	6
CDKN1A	1	DOCK7	3	two hybrid, affinity chromatography technology	Vinayagam A (2011), Fogeron ML (2013)	2
ESR1	0	CREBBP	29	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Sheppard HM (2001), Fan S (2002), Fan S (2002), Fan S (2002), Jin W (2008), Jaber BM (2004), Jaber BM (2004), Heery DM (1997), Ku TK (2007), Crowe DL (2006)	10
SKP2	2	AKT1	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Roe JS (2011), Gao D (2009), Gao D (2009), Chan CH (2013)	9
TSG101	1	MDM2	2	affinity chromatography technology, affinity chromatography technology	Li L (2001), Cheng TH (2007)	2
CDKN1A	1	SET	8	pull down, pull down	Canela N (2003), Carujo S (2006)	2
TK1	0	FLAD1	3	two hybrid	Vinayagam A (2011)	1
CUL2	3	GAPDH	0	affinity chromatography technology	Bennett EJ (2010)	1
CDK4	2	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Serrano M (1993), Xiong Y (1993), Takasaki Y (2001)	3
MDM2	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Latini P (2011), Jacob AG (2014)	2
CDK1	0	CDC20	1	enzymatic study, affinity chromatography technology, enzymatic study	Yudkovsky Y (2000), Huttlin EL (2017), Jia L (2016)	3
CDK3	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDKN1B	1	CDK5	0	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lacy ER (2005), Kabuta T (2013), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	7
PSMD2	2	MDM2	2	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Jin Y (2008), Jin Y (2008), Kulikov R (2010), Kulikov R (2010)	4
MDM4	0	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN1A	1	FLAD1	3	two hybrid, two hybrid	Vinayagam A (2011), Wang J (2011)	2
CDKN1A	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe, affinity chromatography technology, imaging technique	Zhang Z (2004), Zhang Z (2004), Zhang Z (2004), Jin Y (2003), Jin Y (2003), Wang B (2010), Xu H (2010), Xu H (2010), Frum R (2007), Chen TC (2014)	10
TP53	0	STUB1	4	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Muller P (2008), Stankiewicz M (2010), Tripathi V (2007), Tripathi V (2007), Esser C (2005), Lim JH (2011), Wang J (2011), Burch L (2004), Landre V (2013), Horikawa I (2014), Horikawa I (2014), Horikawa I (2014), Fraser JA (2015), Narayan V (2015), Yue X (2016), Parrales A (2016), Parrales A (2016)	17
MAPK8	3	EP300	36	enzymatic study	See RH (2001)	1
RNF126	2	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhi X (2012), Zhi X (2012), Zhi X (2012)	3
CDKN1A	1	CIZ1	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Mitsui K (1999), Mitsui K (1999), Mitsui K (1999)	3
CDK2	0	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
HDAC1	4	MAPK8	3	affinity chromatography technology	Morrison BE (2006)	1
CDC6	0	CDKN1A	1	pull down, imaging technique	Ramachandran N (2004), Chen TC (2014)	2
PSME3	0	MDM2	2	affinity chromatography technology, pull down, pull down, pull down	Zhang Z (2008), Zhang Z (2008), Zhang Z (2008), Liu J (2010)	4
MAPK8	3	JUN	0	enzymatic study, enzymatic study, enzymatic study, pull down, pull down, pull down, two hybrid, pull down, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study	Ishitani T (2003), Nishitoh H (1998), Derijard B (1994), Derijard B (1994), Yazgan O (2002), Tada K (2001), Meyer CF (1996), Cano E (1995), Cano E (1995), Trivedi AK (2007), Zhu F (2006), Zuniga A (1999), Zuniga A (1999), Higashimoto T (2008), Garcia-Guzman M (2000), Singhirunnusorn P (2005), Hofmann TG (2005), Lewis J (2004), Jeon YJ (2009), Yamashita M (2008), Ryoo K (2004), Abell AN (2005), Burns K (1998), Hirano T (2002), Gravestein LA (1998), Dadgostar H (2003), Han YH (2006), Kolluri SK (2003), Chen LY (2003), Manna SK (2010), Gallagher ED (2002), Liu HP (2011), Xia Y (1998), Funakoshi-Tago M (2005), Ho DT (2006), Wang J (2000), Choi HK (2011), Chang TS (2003), Yao K (2009), Chang TS (2003), Dai R (2000), Gupta S (1996), Gupta S (1996), Sundarrajan M (2003), Kallunki T (1994), Kallunki T (1994), Wasserman T (2010), Blonska M (2007), Lee KH (2005), Kadoya T (2005), Katagiri C (2006), Yao K (2007), Wu X (2007), Kato T (2008), Cavigelli M (1995), Katagiri C (2006), Choi BY (2005), Choi BY (2005), Yuan ZQ (2003), Phelan DR (2001), Eliopoulos AG (2006), Hayashi T (2007), Zhang J (2013), Li X (2002), Kendrick TS (2004), Holzberg D (2003), Grau R (2004), Hernandez M (2000), Hwang SG (2014), Larsson H (1999), Rausch O (1997), Morley SJ (2000), Ho JM (2002), Shkoda A (2012), Pop M (2004), Chang HY (1999)	76
CCND2	2	PSMA3	1	affinity chromatography technology	Russo LC (2017)	1
AKT1	1	MAPK14	0	affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, fluorescent resonance energy transfe	Rane MJ (2001), Rane MJ (2001), Hartman AD (2006), Rane MJ (2001), Rane MJ (2001), Ivanov AA (2017)	6
SKP2	2	CCNA2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Bashir T (2010), Rosner M (2009), Rosner M (2004), Zhang H (1995), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	8
CUL4A	2	SKP2	2	affinity chromatography technology	Bondar T (2006)	1
TRIM39	0	TP53	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang L (2012), Zhang L (2012), Zhang L (2012)	3
ESR1	0	SET	8	pull down	Nalvarte I (2010)	1
CREBBP	29	CDKN1A	1	affinity chromatography technology, imaging technique	Fritah A (2005), Chen TC (2014)	2
DAPK3	5	CDKN1A	1	unspecified method, enzymatic study	Burch LR (2004), Burch LR (2004)	2
CCND3	1	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RB1	2	MAPK8	3	affinity chromatography technology	Li H (2001)	1
CCNA2	1	CDC20	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mateo F (2009), Di Fiore B (2010), Di Fiore B (2010), Di Fiore B (2010), Wolthuis R (2008), Wolthuis R (2008), Ge S (2009), Townsend K (2009), Di Fiore B (2010), Mateo F (2009), Mateo F (2009), Huttlin EL (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Hein MY (2015), Voets E (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Huttlin EL (2017), Izawa D (2012), Hein JB (2016)	25
CASP3	0	MDM2	2	enzymatic study, enzymatic study, enzymatic study, imaging technique	Chen L (1997), Pochampally R (1998), Cheng Q (2014), Chen TC (2014)	4
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
BAG6	2	STUB1	4	affinity chromatography technology	Rodrigo-Brenni MC (2014)	1
TK1	0	TUBA1A	13	two hybrid	Vinayagam A (2011)	1
AKT1	1	AKT2	1	affinity chromatography technology	Huttlin EL (2017)	1
SET	8	TP53	0	affinity chromatography technology, pull down	Kim JY (2012), Kim JY (2012)	2
CDKN1A	1	FKBPL	1	pull down, affinity chromatography technology, affinity chromatography technology	Jascur T (2005), Jascur T (2005), Jascur T (2005)	3
TSG101	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Li L (2001), Li L (2001)	2
DDB1	6	PCNA	0	affinity chromatography technology	Angers S (2006)	1
TP53	0	DDB1	6	affinity chromatography technology	Fogeron ML (2013)	1
GADD45G	0	CCNB1	3	pull down	Vairapandi M (2002)	1
SET	8	CCNB1	3	affinity chromatography technology	Carujo S (2006)	1
CCNA2	1	CDK4	2	affinity chromatography technology, affinity chromatography technology	Datta NS (1998), Kikuchi R (2014)	2
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
KAT2B	2	PARP1	3	enzymatic study	Rajamohan SB (2009)	1
MDM2	2	NPM1	0	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Kurki S (2004), Kurki S (2004), Nicholson J (2012), Nicholson J (2012)	4
CDC45	1	CDK2	0	affinity chromatography technology, affinity chromatography technology	Alexandrow MG (2005), Alexandrow MG (2005)	2
SKP2	2	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Yam CH (1999), Calvisi DF (2009), Gao D (2009), Bashir T (2010), Yao ZP (2006), Rosner M (2009), Lyapina SA (1998), Zhang H (1995), Zhang H (1995), Inuzuka H (2012), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	17
CDK2	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Koundrioukoff S (2000), Zhang H (1993), Neganova I (2011), Wu SM (1998), Chen Z (2002), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	8
CEBPA	0	SKP2	2	two hybrid	Wang J (2011)	1
CDKN1A	1	CCNE1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique	McKenzie PP (2003), McKenzie PP (2003), Jeon Y (2007), Derjuga A (2001), Datta NS (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bresnahan WA (1996), Bendjennat M (2003), Bao GC (2006), Chen J (1996), Chen J (1996), Chen J (1996), Levkau B (1998), Poon RY (1996), Zhao J (1998), Wang J (2011), Fogeron ML (2013), Chen TC (2014)	20
CDK1	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
CDC20	1	CCNA1	3	affinity chromatography technology, two hybrid, affinity chromatography technology	Ohtoshi A (2000), Ohtoshi A (2000), Gao D (2009)	3
CDK2	0	CDK1	0	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Huttlin EL (2017)	2
CDKN1A	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Huttlin EL (2017)	2
TP53	0	CCND1	1	affinity chromatography technology	Yang P (2016)	1
TK1	0	TP53	0	two hybrid, two hybrid	Stelzl U (2005), Vinayagam A (2011)	2
CCNA2	1	CDK6	0	affinity chromatography technology	Datta NS (1998)	1
CCNA2	1	EP300	36	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAPK8	3	PSMD2	2	affinity chromatography technology	Hein MY (2015)	1
CDC20	1	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
AKT1	1	CDKN1A	1	pull down, enzymatic study, imaging technique, enzymatic study	Heron-Milhavet L (2006), Heron-Milhavet L (2006), Chen TC (2014), Roessig L (2001)	4
CEBPA	0	JUN	0	affinity chromatography technology	Zada AA (2006)	1
CDK2	0	CDK6	0	biochemical, imaging technique	Cheng A (2000), Chen TC (2014)	2
PCNA	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Jascur T (2011), Jascur T (2011), Dar A (2014), Terai K (2010), Higa LA (2006), Higa LA (2006)	6
CDKN1A	1	BAG6	2	two hybrid, two hybrid	Vinayagam A (2011), Wang J (2011)	2
MDM2	2	YWHAQ	0	affinity chromatography technology, pull down, affinity chromatography technology	Pereg Y (2006), Wang B (2010), Wang B (2010)	3
DTL	0	MDM2	2	affinity chromatography technology	Banks D (2006)	1
CCNB1	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Lin Z (2015), Lin Z (2015)	2
MAPK14	0	CIZ1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDK4	2	BAG6	2	two hybrid	Stelzl U (2005)	1
CDK5	0	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Huttlin EL (2017)	3
CDKN1A	1	EP300	36	pull down, affinity chromatography technology	Cazzalini O (2008), Cazzalini O (2008)	2
MDM4	0	PSMD2	2	affinity chromatography technology, pull down, biochemical, affinity chromatography technology	Jin Y (2008), Jin Y (2008), Jin Y (2008), Jin Y (2008)	4
PARP1	3	PCNA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Frouin I (2003), Cazzalini O (2010), Cazzalini O (2010), Lee CH (2010), Pozo FM (2011), Sekimoto T (2010)	6
CCNA2	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Amador V (2007), Horton LE (1997), Lin ML (2011), Lin ML (2011), OConnor PM (1993), Varjosalo M (2013), Kikuchi R (2014), Mateo F (2009), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	13
CCND2	2	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study	Moorthamer M (1999), Sweeney KJ (1997), Jiang W (1998), Welcker M (1998)	4
GADD45A	1	MDM2	2	affinity chromatography technology, enzymatic study	Gao M (2013), Gao M (2013)	2
RB1	2	CDKN1A	1	affinity chromatography technology, pull down	Nakanishi M (1999), Nakanishi M (1999)	2
CDK1	0	CKS1B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Havugimana PC (2012), Hixon ML (1998), Varjosalo M (2013), Radulovic M (2010), Rolland T (2014), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	11
TP53	0	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNA2	1	CCNA1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RB1	2	HDAC1	4	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Dick FA (2000), Fuks F (2000), Puri PL (2001), Puri PL (2001), Wang S (2002), Luo RX (1998), Luo RX (1998), Lai A (1999), Lai A (1999), Ferreira R (1998), Kimura H (2003), Qiu Z (2008), Fedele M (2006), Brown VD (2002), Khan MM (2001), Dasgupta P (2004), Chang YC (2001), Dahiya A (2000), Zhang HS (2000), Tokitou F (1999), Nguyen DX (2004), Takaki T (2004), Magnaghi-Jaulin L (1998), Magnaghi-Jaulin L (1998), Brehm A (1998), Brehm A (1998), Brehm A (1998), Sun JM (2007), Fan LX (2012), Harbour JW (1999), Brehm A (1999), Joshi P (2013), Chen TT (2000), Chen TT (2000), Chen TT (2000), Chen TT (2000)	36
CDK3	0	CKS1B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDK2	0	GAPDH	0	affinity chromatography technology	Neganova I (2011)	1
TP53	0	EP300	36	pull down, genetic interference, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, unspecified method, affinity chromatography technology, enzymatic study, unspecified method, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, unspecified method	An W (2004), Pastorcic M (2000), Livengood JA (2002), Livengood JA (2002), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Tang Y (2008), Wang H (2008), Valbuena A (2008), Shi D (2009), Vega FM (2004), Finlan L (2004), Groenroos E (2004), Zhao Y (2006), Roe JS (2006), Pedeux R (2005), Sekaric P (2007), Pan X (2009), Tang Y (2006), Sen GS (2011), Li Y (2012), Li Y (2012), Gillotin S (2010), Grossman SR (2003), Issaeva N (2004), Kitagawa M (2008), Sabbatini P (2002), Burge S (2009), Zilfou JT (2001), Issaeva N (2004), Issaeva N (2004), Feng H (2009), Feng H (2009), Lill NL (1997), Dornan D (2004), Dornan D (2004), Di Agostino S (2006), Wells M (2008), Fath DM (2006), Kobet E (2000), Costanzo A (2002), Kumazawa T (2011), Borger DR (2006), Cui D (2013), Borger DR (2006), Lee SJ (2013), Tang HY (2006), Lin C (2011), Choi WI (2014), Ding G (2013), Kim MK (2013), Ali A (2013), Wu G (2014), Mizuguchi Y (2012), Sinha S (2012), Sinha S (2012), Her YR (2013), Her YR (2013), Wu SY (2009), Wu SY (2009), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Gu W (1997), Teufel DP (2007), Mantovani F (2007), Mantovani F (2007), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), MacPartlin M (2005), Mujtaba S (2004), Wang YH (2003), Chen H (1999), Tang Z (2013), Graczyk A (2013), Graczyk A (2013), Chan HM (2001), Thomas MC (2005), Miller Jenkins LM (2015), Miller Jenkins LM (2015), Koh DI (2014), Koh DI (2014), Koh DI (2014), Li H (2015), Chen LF (2005), Shi D (2016), Wright DG (2016), Zhang X (2016), Procopio MG (2015), Tong Q (2015)	95
CDKN1A	1	PARP1	3	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Frouin I (2003), Cazzalini O (2010), Cazzalini O (2010), Lee CH (2010)	4
JUN	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, pull down	Zhang X (1999), Zhang X (1999), Zhang X (1999)	3
PCNA	0	CDC45	1	biochemical	Wan C (2015)	1
CDK14	4	RB1	2	enzymatic study, enzymatic study	Jiang M (2009), Shu F (2007)	2
RB1	2	BAG6	2	affinity chromatography technology	Hein MY (2015)	1
KAT2B	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study	Jin Y (2002), Wang H (2008), Zhao Y (2006), Roe JS (2006), Perez RE (2010), Tang Y (2006), Zhao LY (2003), Liu L (1999), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Harrod R (2003), MacPartlin M (2005), Chen H (1999), Kang H (2009)	15
MDM2	2	JUN	0	pull down	Miyamoto-Sato E (2010)	1
TSG101	1	DAPK3	5	imaging technique	Felten A (2012)	1
CUL4A	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Angers S (2006), Jin J (2006), Wang H (2006), Kapetanaki MG (2006), Matsuda N (2005), Hu J (2004), Hu J (2004), Hu J (2004), Ahn J (2010), Maddika S (2009), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), He YJ (2006), McCall CM (2008), McCall CM (2008), Shiyanov P (1999), Bennett EJ (2010), Gastaldello S (2012), Kanei-Ishii C (2012), Hodgson AJ (2012), Kulaksiz G (2005), Wu Z (2012), Wu Z (2012), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Rao F (2014), Wan C (2015), Liu Y (2015), Zha Z (2015), Mouysset J (2015), Gao J (2015), Yang Y (2016), Yang Y (2016), Scherer PC (2016), Eichner R (2016), Mo Y (2017), Mo Y (2017), Peng Z (2016), Higa LA (2006), Ohtake F (2007)	46
PARP1	3	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Hassa PO (2005), Hassa PO (2005), Hang CT (2010), Rajamohan SB (2009)	4
EP300	36	PCNA	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Hasan S (2001), Hasan S (2001), Hasan S (2001), Hong R (2003), Hong R (2003), Cazzalini O (2008), Cazzalini O (2008), Naryzhny SN (2004), Cazzalini O (2014), Cazzalini O (2014)	10
CDKN1A	1	CUL2	3	affinity chromatography technology, affinity chromatography technology	Starostina NG (2010), Starostina NG (2010)	2
SKP2	2	RB1	2	affinity chromatography technology, affinity chromatography technology	Ji P (2004), Ji P (2004)	2
YWHAQ	0	ESR1	0	pull down	Zilliacus J (2001)	1
CDK2	0	YWHAQ	0	affinity chromatography technology	Neganova I (2011)	1
MAPK8	3	AKT1	1	enzymatic study	Xiao L (2010)	1
CDK14	4	CDKN1A	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shu F (2007), Shu F (2007), Shu F (2007), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	6
PARP1	3	TP53	0	affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, pull down, pull down	Gueven N (2004), Malanga M (1998), Vaziri H (1997), Vaziri H (1997), Wesierska-Gadek J (2003), Simbulan-Rosenthal CM (2003)	6
PSMA3	1	PSME3	0	biochemical	Wan C (2015)	1
KAT2B	2	JUN	0	affinity chromatography technology	Tsai LN (2008)	1
MAPK14	0	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EP300	36	DDB1	6	affinity chromatography technology, affinity chromatography technology	Datta A (2001), Rapic-Otrin V (2002)	2
DDB1	6	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006), Jin J (2006), Higa LA (2006), Rossi M (2013), Shibata E (2011), Higa LA (2006), Higa LA (2006)	8
DDB1	6	SKP2	2	affinity chromatography technology	Bondar T (2006)	1
CKS1B	0	CCNE2	2	affinity chromatography technology	Huttlin EL (2017)	1
AKT1	1	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Lin WN (2008), Lee IT (2010), Sundaresan NR (2011), Howie HL (2011), Chen J (2004), Chen J (2004)	6
CDK2	0	ESR1	0	enzymatic study, affinity chromatography technology	Zhou W (2014), Zhou W (2014)	2
TP53	0	MKRN1	1	affinity chromatography technology	Lee EW (2009)	1
MAPK14	0	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAPK14	0	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	MAPK14	0	protein complementation assay, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Srivastav RK (2011), Zhang S (2006), Mo JS (2010), Gong X (2010), Perfettini JL (2005), Perfettini JL (2005), Bulavin DV (1999), Bulavin DV (1999)	8
NPM1	0	BCCIP	1	affinity chromatography technology	Hein MY (2015)	1
AKT1	1	CDKN1B	1	enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology	Fujita N (2002), Fujita N (2002), Nacusi LP (2006), Chen TC (2014), Zhang H (2017), Zhang H (2017)	6
CDK5	0	CDK14	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PSMD2	2	CDKN1A	1	biochemical, affinity chromatography technology	Jin Y (2008), Jin Y (2008)	2
TUBA1A	13	RB1	2	genetic interference	Srivas R (2016)	1
CCND3	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Datta NS (1998), Bockstaele L (2006), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	5
CDKN1B	1	CCND1	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin J (2001), Guidoboni M (2005), Vlach J (1996), Vlach J (1997), Tsai CH (2009), Ciarallo S (2002), Bindra RS (2002), Kossatz U (2006), Grimmler M (2007), Rolland T (2014), Hein MY (2015), Barbash O (2009), Huttlin EL (2017)	13
PCNA	0	CCNE2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CXCL13	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology	Wang Z (2013), Wang Z (2013)	2
CDK2	0	NPM1	0	enzymatic study	Tokuyama Y (2001)	1
PSMA3	1	PSMD2	2	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
OPTN	1	YWHAQ	0	affinity chromatography technology	Li S (2011)	1
AKT1	1	STUB1	4	affinity chromatography technology, affinity chromatography technology	Dickey CA (2008), Su CH (2011)	2
CCNA2	1	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joaquin M (2003), Amador V (2007), Wu G (1997), Lin ML (2011), Chen J (1996), Levkau B (1998), Poon RY (1996), Fogeron ML (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	11
TK1	0	CDC20	1	pull down	Ke PY (2004)	1
TK1	0	GAPDH	0	two hybrid, two hybrid	Stelzl U (2005), Vinayagam A (2011)	2
CREBBP	29	PCNA	0	affinity chromatography technology, pull down, enzymatic study	Cazzalini O (2014), Cazzalini O (2014), Cazzalini O (2014)	3
CDC6	0	CDC20	1	pull down	Ke PY (2004)	1
MAPK14	0	MAPK8	3	affinity chromatography technology	Chan PM (2008)	1
JUN	0	HDAC1	4	affinity chromatography technology	Tenbrock K (2006)	1
CDK4	2	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Nair JS (2009), Takaki T (2004), Deep G (2006), Kehn K (2004), Scholz A (2003), Gladden AB (2003), Mori S (1999), Higashi H (1996), Musgrove EA (1996), Sarmento LM (2005), Kim KS (2002), Li J (2002), Garcia-Morales P (2006), Tsai CH (2009), Miralem T (2003), Toji S (2004), Halder SK (2005), Dynlacht BD (1997), Mandal M (1998), Voit R (1999), Annicotte JS (2006), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Kitagawa M (1996), Anders L (2011), Gaiddon C (2003), Seo DW (2006), Kabuta T (2013), Lee B (2006), Kossatz U (2006), Zarkowska T (1997), Nakanishi M (1999), Iyer NG (2007), Guidoboni M (2005), Barbash O (2009), Wang C (2001), Denicourt C (2008), Pan W (2001)	39
RB1	2	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study	Iyer NG (2007), Iyer NG (2007), Chan HM (2001)	3
CKS1B	0	CCNE1	1	affinity chromatography technology	Huttlin EL (2017)	1
MAPK14	0	CDKN1A	1	enzymatic study, affinity chromatography technology	Kim GY (2002), Kim GY (2002)	2
CCNA2	1	CDKN1B	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joaquin M (2003), Schulman BA (1998), Datta NS (1998), Vlach J (1997), Levkau B (1998), Grimmler M (2007), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
AKT1	1	GAPDH	0	affinity chromatography technology	Klein JB (2005)	1
MAPK8	3	STAT3	0	enzymatic study, affinity chromatography technology	Lim CP (1999), Lo RK (2006)	2
RB1	2	CCND3	1	two hybrid, affinity chromatography technology, pull down	Stern MD (2007), Bockstaele L (2006), Jaenicke RU (1996)	3
CREBBP	29	TP53	0	enzymatic study, pull down, genetic interference, pull down, enzymatic study, fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, imaging technique, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, affinity chromatography technology, unspecified method, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, enzymatic study, enzymatic study, pull down, x-ray crystallography, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Ito A (2002), Livengood JA (2002), Livengood JA (2002), Giebler HA (2000), Tang Y (2008), Jenkins LM (2009), Shi D (2009), Zhao Y (2006), Saifudeen Z (2005), Scolnick DM (1997), Scolnick DM (1997), Gu W (1997), Gu W (1997), Matsuda S (2004), Pasqualucci L (2011), Lee SK (1999), Dai C (2011), Lee CW (2010), Ferreon JC (2009), Ruas JL (2010), Ruas JL (2010), Huang WC (2007), Huang WC (2007), Mujtaba S (2004), Mujtaba S (2004), Mujtaba S (2004), Mujtaba S (2004), Col E (2002), Jansma AL (2014), Jansma AL (2014), Krois AS (2016), Hasegawa K (2008), Huang X (2013), Huang X (2013), Piskacek M (2016)	35
SKP2	2	CKS1B	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Wang W (2003), Wang W (2003), Sitry D (2002), Sitry D (2002), Ganoth D (2001), Calvisi DF (2008), Xu S (2007), Ungermannova D (2005), Spruck C (2001), Yao ZP (2006), Seeliger MA (2005), Huang KS (2005), Rodier G (2008), Ungermannova D (2013), Radulovic M (2010), Huttlin EL (2017)	16
CUL2	3	SKP2	2	affinity chromatography technology	Kimura Y (2007)	1
CDK1	0	CDC6	0	enzymatic study	Jiang W (1999)	1
GAPDH	0	CCNB1	3	pull down, affinity chromatography technology	Carujo S (2006), Carujo S (2006)	2
CCNB1	3	CDKN1B	1	affinity chromatography technology	Hein MY (2015)	1
CDKN1A	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abbas T (2008), Abbas T (2008), Gao J (2015)	3
CDKN1A	1	BCCIP	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Ono T (2000), Ono T (2000), Ono T (2000), Meng X (2004)	4
CEBPA	0	PARP1	3	affinity chromatography technology, pull down, affinity chromatography technology	Yin H (2006), Yin H (2006), Yin H (2006)	3
CDK6	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Garcia-Morales P (2006), Aprelikova O (1995), Yarbrough WG (1999), Dynlacht BD (1997), Jiang W (1998), Anders L (2011), Nakanishi M (1999), Iyer NG (2007)	8
GADD45G	0	CDK1	0	pull down	Vairapandi M (2002)	1
MAPK14	0	CASP3	0	affinity chromatography technology	Alvarado-Kristensson M (2004)	1
GADD45A	1	TP53	0	two hybrid	Vinayagam A (2011)	1
CDK5	0	CCNB1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	5
PIM1	2	CDKN1A	1	enzymatic study, pull down	Wang Z (2002), Wang Z (2002)	2
CCND1	1	RB1	2	pull down, genetic interference, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Siegert JL (2000), Siegert JL (2000), Dowdy SF (1993), Chan HM (2001), Dasgupta P (2004), Dasgupta P (2004), Sweeney KJ (1997), Higashi H (1996), Musgrove EA (1996), Yarbrough WG (1999), Connell-Crowley L (1997), Kitagawa M (1996), Poon RY (1996), Gaiddon C (2003), Zarkowska T (1997), Nakanishi M (1999), Welcker M (1998)	17
CCNE1	1	CDK1	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Koff A (1992), Koff A (1992), Horton LE (1997)	4
PSMA3	1	GAPDH	0	affinity chromatography technology	Fedorova OA (2011)	1
CDKN1B	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Miranda-Carboni GA (2008), Bondar T (2006), Li B (2006), Li B (2006), Gao J (2015)	5
ESR1	0	NPM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Ambrosino C (2010), Ambrosino C (2010), Tarallo R (2011), Nalvarte I (2010)	4
YWHAQ	0	PSME3	0	pull down	Meek SE (2004)	1
JUN	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Teyssier C (2001), Baron S (2007), Ruiz ML (2013), Ruiz ML (2013)	4
CDK5	0	CCNE1	1	affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2017)	2
CCNE2	2	CDKN1A	1	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lauper N (1998), Zariwala M (1998), Ramachandran N (2004), Fogeron ML (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
CDK4	2	HDAC1	4	genetic interference	Shen JP (2017)	1
MDM4	0	TP53	0	enzymatic study, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, protein complementation assay, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, fluorescent resonance energy transfe, pull down	Badciong JC (2002), Shvarts A (1997), Shvarts A (1997), Tang Y (2008), Okamoto K (2005), Chen L (2005), Wang X (2001), Ohtsubo C (2009), Zdzalik M (2010), Singh RK (2007), Kim S (2010), Li M (2011), Li M (2011), David Y (2011), de Graaf P (2003), Wade M (2012), Wade M (2012), Wade M (2012), Stad R (2000), Stad R (2000), Bernal F (2010), Bernal F (2010), Bernal F (2010), Bernal F (2010), Miller KR (2010), Zuckerman V (2009), Kallen J (2009), Czarna A (2009), Czarna A (2009), Popowicz GM (2008), Hu B (2007), Sharp DA (1999), Li C (2002), Di Conza G (2012), Mancini F (2009), Mancini F (2009), Wu S (2012), Shan B (2012), Wu S (2012), Wu S (2012), Ranaweera RS (2013), Bista M (2013), Bista M (2013), Wang CL (2014), Wang CL (2014), Rallapalli R (1999), Chang YS (2013), Chang YS (2013), Tan BX (2014), Huttlin EL (2015), Sanchez MC (2010), Sanchez MC (2010), Li YC (2014), Li X (2015), Chen X (2015), Chen L (2015), Chen L (2015), Chen L (2015), Wei X (2016), Wei X (2016), Xie X (2016), Huttlin EL (2017), Borcherds W (2017), Shangary S (2008), Ivanov AA (2017), Mancini F (2016)	66
CDKN1A	1	CDKN1B	1	genetic interference, imaging technique	Hsu SP (2008), Chen TC (2014)	2
GADD45G	0	ESR1	0	pull down	Yi YW (2000)	1
CDK6	0	CDC6	0	enzymatic study	Anders L (2011)	1
TP53	0	CDKN1A	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Tian H (2002), Vinayagam A (2011), Kinyamu HK (2003), Giono LE (2007), Chen TC (2014)	5
CDK4	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PCNA	0	GADD45A	1	two hybrid, far western blotting, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Smith ML (1994), Chen IT (1995), Vairapandi M (2000), Hall PA (1995), Hall PA (1995), Yang Q (2000), Smith ML (1994), Vairapandi M (2000), Smith ML (1994), Yang Q (2000), Vairapandi M (2000), Vairapandi M (2000), Kim HL (2013), Sanchez R (2010)	14
CUL4A	2	NPM1	0	affinity chromatography technology	Bennett EJ (2010)	1
CDKN1A	1	PCNA	0	two hybrid, pull down, pull down, pull down, pull down, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Frouin I (2003), Watanabe H (1998), Fotedar R (1996), Jonsson ZO (1998), Gulbis JM (1996), Touitou R (2001), Yu P (2001), Yu P (2001), Chen X (2007), Chen X (2007), Wang SC (2006), Carujo S (2006), Garcia-Wilson E (2005), Howlett NG (2009), Jin Y (2008), Lee JY (2009), Ando T (2001), Ando T (2001), Takasaki Y (2001), Logette E (2011), Mistafa O (2010), Mistafa O (2010), Bruning JB (2004), Punchihewa C (2012), Mattock H (2001), Waga S (1994), Waga S (1994), Poon RY (1996), Zhang Y (1999), Warbrick E (1995), Warbrick E (1995), Poon RY (1998), Poon RY (1998), Wang J (2011), Fogeron ML (2013), Rolland T (2014), Rizzardi LF (2014), Trombetta A (2013), Trombetta A (2013), Kim DH (2010), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Coleman KE (2015), Huttlin EL (2017), Roessig L (2001), Roessig L (2001)	48
RB1	2	TP53	0	affinity chromatography technology, pull down	Delston RB (2011), Sommer MH (1994)	2
CCNA1	3	SKP2	2	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ji P (2006), Ji P (2006), Ji P (2006), Yam CH (2000), Gao D (2009), Ji P (2007)	6
CCND1	1	CDKN1A	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Lin J (1996), Guidoboni M (2005), Garcia-Wilson E (2005), Santiago FS (2007), Santiago FS (2007), Zheleva DI (2002), Ruas M (2007), Chen J (1996), Chen J (1996), Poon RY (1996), Ramachandran N (2004), Wang J (2011), Fogeron ML (2013), Rolland T (2014), Yu H (2011), Datta D (2015), Hukkelhoven E (2012), Hukkelhoven E (2012), Hukkelhoven E (2012), Huttlin EL (2017), Welcker M (1998)	21
CDC20	1	HDAC1	4	affinity chromatography technology, biochemical	Yoon YM (2004), Yoon YM (2004)	2
CUL2	3	LRR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Kamura T (2004), Kamura T (2004), Kamura T (2004)	5
TSG101	1	BAG6	2	affinity chromatography technology	Schlundt A (2009)	1
MDM2	2	GAPDH	0	affinity chromatography technology	Frum R (2007)	1
MDM2	2	AKT1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique	Lin HK (2002), Ogawara Y (2002), Zhou BP (2001), Zhou BP (2001), Kim CK (2011), Kim CK (2011), Zhu QS (2011), Milne D (2004), Deep G (2008), Deep G (2008), Chen TC (2014)	11
GAPDH	0	SET	8	pull down, affinity chromatography technology	Carujo S (2006), Carujo S (2006)	2
CDK6	0	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Lin J (2001), Sweeney KJ (1997), Varjosalo M (2013), Ivanov AA (2017)	4
HDAC1	4	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Ito A (2002), Ito A (2002), Ito A (2002), Gaughan L (2005), Gaughan L (2005)	5
ESR1	0	PARP1	3	affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Tarallo R (2011)	2
CEBPA	0	HDAC1	4	affinity chromatography technology, biochemical, imaging technique, affinity chromatography technology	Duan H (2005), Matsunaga N (2012), Matsunaga N (2012), Girard N (2013)	4
MDM4	0	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Uchida C (2006), Uchida C (2006), Zhang H (2015), Zhang H (2015)	4
TP53	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology	Liu G (2000), Duong V (2007), Saxena R (2016)	3
PSMD2	2	PSME3	0	biochemical	Havugimana PC (2012)	1
CCND1	1	ESR1	0	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Zwijsen RM (1997), Zwijsen RM (1997), Zwijsen RM (1997), Wang C (2005), Wang C (2005)	5
CDK1	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Amador V (2007), Ando T (2001), Lin ML (2011), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
RB1	2	MDM2	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Hsieh JK (1999), Nguyen DX (2004), Zheng Z (2012), Sdek P (2005), Delston RB (2011), Delston RB (2011), Sdek P (2004), Sdek P (2004), Xiao ZX (1995), Xiao ZX (1995), Xiao ZX (1995), Uchida C (2006), Markham D (2006), Chan HM (2001), Chan HM (2001), Zhang H (2015), Zhang H (2015), Jaenicke RU (1996)	18
CDKN1A	1	KAT2B	2	affinity chromatography technology, affinity chromatography technology	Dai M (2012), Dai M (2012)	2
TP53	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Banks D (2006), Banks D (2006), Hampp S (2016), Hampp S (2016)	4
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
CCNA1	3	CDK1	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Sweeney C (1996), Lukas J (1992), Desai D (1995), Rohaly G (2005)	4
CDC20	1	CDKN1A	1	affinity chromatography technology, affinity chromatography technology	Amador V (2007), Fogeron ML (2013)	2
CDKN1B	1	DDB1	6	affinity chromatography technology	Iovine B (2011)	1
CCNB1	3	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin Z (2015), Lin Z (2015), Huttlin EL (2017)	3
PSMA3	1	MDM2	2	pull down	Xu H (2010)	1
CCND1	1	CDK2	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sweeney KJ (1997), Higashi H (1996), Higashi H (1996), Varjosalo M (2013), Hein MY (2015), Huttlin EL (2017)	6
TP53	0	GAPDH	0	affinity chromatography technology	Sen N (2008)	1
CCND2	2	CDKN1B	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Huttlin EL (2015), Huttlin EL (2017)	3
CDKN1A	1	GAPDH	0	affinity chromatography technology, pull down	Carujo S (2006), Carujo S (2006)	2
CDC45	1	CDKN1A	1	pull down, imaging technique	Ramachandran N (2004), Chen TC (2014)	2
CCNE1	1	CDK6	0	affinity chromatography technology, fluorescent resonance energy transfe	Datta NS (1998), Ivanov AA (2017)	2
PARP1	3	JUN	0	affinity chromatography technology	Kim BK (2014)	1
CDK3	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	4
HDAC1	4	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mayanil CS (2006), Chuang HC (2006), Chuang HC (2006)	3
CDK2	0	CKS1B	0	x-ray crystallography, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Bourne Y (1996), Xu S (2007), Yao ZP (2006), Seeliger MA (2005), Varjosalo M (2013), Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	12
CDK5	0	CCND3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CREBBP	29	PARP1	3	enzymatic study, imaging technique	Hassa PO (2005), Chen H (2014)	2
STUB1	4	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Biswas K (2017), Biswas K (2017), Biswas K (2017)	3
DAPK3	5	TP53	0	enzymatic study	Burch LR (2004)	1
CDK3	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
JUN	0	RB1	2	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down	Nishitani J (1999), Nishitani J (1999), Nishitani J (1999), Nead MA (1998), Nead MA (1998)	5
CDKN1A	1	NPM1	0	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Xiao J (2009), Xiao J (2009), Xiao J (2009), Xiao J (2009), Li J (2005)	5
DDB1	6	ESR1	0	affinity chromatography technology	Ohtake F (2007)	1
CDK2	0	DAPK3	5	affinity chromatography technology	Hein MY (2015)	1
CKS1B	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jackman M (2002), Wolthuis R (2008), Mateo F (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
DTL	0	TP53	0	affinity chromatography technology, enzymatic study	Banks D (2006), Banks D (2006)	2
CEBPA	0	ESR1	0	pull down	Boruk M (1998)	1
CDKN1A	1	CEBPA	0	pull down, two hybrid	Timchenko NA (1997), Timchenko NA (1997)	2
CDK1	0	TP53	0	enzymatic study, affinity chromatography technology	Luciani MG (2000), Ababneh M (2001)	2
RNF126	2	SKP2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP53	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique	Ito A (2002), Wang C (2005), Dohi Y (2008), Jin W (2008), Lei Q (2006), Wu Y (2001), Wu Y (2001), Luo J (2000), Juan LJ (2000), Juan LJ (2000), Juan LJ (2000), Murphy M (1999), Insinga A (2004), Sun JM (2007), Yu XY (2010), Sinha S (2010), Sinha S (2010), Li Y (2012), Di Agostino S (2006), Pavithra L (2009), Pavithra L (2009), Luo J (2000), Chen TC (2014), Park EK (2015), Park EK (2015), Park EK (2015)	26
CCNB1	3	RB1	2	enzymatic study, enzymatic study	Jiang W (1998), Knudsen ES (1997)	2
CCND3	1	PCNA	0	pull down	Matsuoka S (1994)	1
CUL4A	2	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Lo YH (2012), Banks D (2006)	3
AKT2	1	ESR1	0	enzymatic study, affinity chromatography technology	Sun M (2001), Sun M (2001)	2
CDK5	0	RB1	2	enzymatic study	Moorthamer M (1999)	1
STAT3	0	CDKN1A	1	affinity chromatography technology, imaging technique	Coqueret O (2000), Chen TC (2014)	2
CDKN1A	1	OPTN	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Journo C (2009), Journo C (2009), Journo C (2009)	3
CCNE1	1	CDC6	0	enzymatic study	Jiang W (1999)	1
PCNA	0	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology	Milutinovic S (2002), Milutinovic S (2002), Naryzhny SN (2004)	3
CDKN1A	1	MKRN1	1	affinity chromatography technology, affinity chromatography technology	Lee EW (2009), Lee EW (2009)	2
CDK2	0	DOCK7	3	affinity chromatography technology	Hein MY (2015)	1
PCNA	0	GAPDH	0	affinity chromatography technology, pull down	Naryzhny SN (2010), Naryzhny SN (2010)	2
EP300	36	CCND1	1	pull down, affinity chromatography technology, affinity chromatography technology	Ratineau C (2002), Fu M (2005), Fu M (2005)	3
CDC20	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Bashir T (2004), Huttlin EL (2017)	2
CDKN1A	1	TUBA1A	13	two hybrid, affinity chromatography technology	Vinayagam A (2011), Fogeron ML (2013)	2
TP53	0	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
TRIM39	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology	Zhang L (2012), Zhang L (2012)	2
SKP2	2	STUB1	4	affinity chromatography technology	Huang Z (2004)	1
CDC20	1	CCNB1	3	enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Garnett MJ (2009), ODonovan KJ (2010), Ke PY (2004), Braunstein I (2007), van Zon W (2010), van Zon W (2010), Pfleger CM (2001), Wolthuis R (2008), Kwan PS (2013), Tian W (2012), Han JS (2013), Lim HJ (2013), Han JS (2014), Brown NG (2014), Townsend K (2009), Sedgwick GG (2013), Lara-Gonzalez P (2011), Wu T (2010), Shoji S (2014), Vodermaier HC (2003), Kim HS (2011), Wu T (2010), Uzunova K (2012), Shoji S (2014), Sedgwick GG (2013), Lara-Gonzalez P (2011), Diaz-Martinez LA (2015), Brown NG (2015), Lischetti T (2014), Tipton AR (2013), Lee SB (2015), Lee SB (2015), Jia L (2016)	33
DTL	0	YWHAQ	0	affinity chromatography technology, affinity chromatography technology	Dar A (2014), Dar A (2014)	2
MAPK8	3	TP53	0	affinity chromatography technology, pull down, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down	Hu MC (1997), Yin ZM (2004), Yin ZM (2004), Fuchs SY (1998), Topisirovic I (2009), Drago-Ferrante R (2008), Wang J (2000), Chang NS (2003), Fuchs SY (1998)	9
SKP2	2	ESR1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhou W (2014), Zhou W (2014), Zhou W (2014)	3
GADD45A	1	CDKN1A	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Zhao H (2000), Zhao H (2000), Yang Q (2000), Yang Q (2000)	4
CDKN1B	1	CDK4	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Lin J (2001), Cariou S (2000), Guidoboni M (2005), Bustany S (2011), Hsu SP (2008), Radu M (2008), Mori S (1999), Kokontis JM (1998), Orend G (1998), Vlach J (1996), Vlach J (1997), Ciarallo S (2002), Wang Y (2008), Bockstaele L (2006), Mandal M (1998), Larrea MD (2009), Seo DW (2006), Kossatz U (2006), Kossatz U (2006), Mallampalli RK (2013), Varjosalo M (2013), Huttlin EL (2015), Chen TC (2014), Carrasco-Garcia E (2011), Huttlin EL (2017)	25
CCND1	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang H (1993), Zhang H (1993), Hein MY (2015), Huttlin EL (2017)	4
CCND1	1	PCNA	0	pull down, affinity chromatography technology, affinity chromatography technology	Matsuoka S (1994), Xiong Y (1993), Zhang H (1993)	3
CCNB1	3	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Yang Q (2000), Pines J (1989), Kong M (2000), Amador V (2007), Paulsen MT (2006), Niida H (2005), Pereg Y (2010), Tamura D (2010), Kiviharju-af Haellstroem TM (2007), Pan ZQ (1993), Pan ZQ (1993), Pan ZQ (1993), van Zon W (2010), Desai D (1995), Vazquez-Novelle MD (2010), Smith EM (2008), Poon RY (1996), OConnor PM (1993), Fosbrink M (2009), Linares JF (2011), Varjosalo M (2013), Felzien LK (1998), Toby GG (2003), So J (2015), Huttlin EL (2015), Wan C (2015), Jenkins RH (2014), Hein MY (2015), Hein MY (2015), Voets E (2015), Lin Z (2015), Lin Z (2015), Huttlin EL (2017)	34
MDM2	2	RNF126	2	two hybrid	Woodsmith J (2012)	1
MAPK14	0	EP300	36	pull down, enzymatic study, affinity chromatography technology	Pillai VB (2011), Pillai VB (2011), Saha RN (2007)	3
CKS1B	0	CCNA1	3	pull down	Radulovic M (2010)	1
ESR1	0	MDM2	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down	Liu G (2000), Kinyamu HK (2003), Duong V (2007), Duong V (2007), Duong V (2007), Duong V (2007), Saji S (2001), Saji S (2001)	8
TP53	0	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNA2	1	TP53	0	pull down	Luciani MG (2000)	1
CREBBP	29	KAT2B	2	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Tini M (2002), Cho H (1998), Cho H (1998), Cho H (1998), Korzus E (1998), Korzus E (1998), Korzus E (1998), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996)	10
CDK1	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Lees JA (1991), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Knudsen ES (1997), Pan W (2001)	8
AKT1	1	NPM1	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Lee SB (2008), Lee SB (2008), Lee SB (2008), Lee SB (2008)	4
CCNA2	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Naderi S (2005), Varshochi R (2005), Di Fiore B (2010), Mateo F (2009), Abbas T (2007), Schulman BA (1998), Datta NS (1998), Wu G (1997), Sebastian B (1993), Liu S (2009), Ciarallo S (2002), Wolthuis R (2008), Vicent GP (2011), Zhang H (1995), Sayle KL (2003), Jeffrey PD (1995), Davies TG (2001), Cook A (2002), Pevarello P (2006), Levkau B (1998), Poon RY (1996), OConnor PM (1993), Davies TG (2002), Kontopidis G (2003), Andrews MJ (2004), Pevarello P (2004), Pevarello P (2005), Varjosalo M (2013), Varjosalo M (2013), Kikuchi R (2014), Kikuchi R (2014), Mateo F (2009), So J (2015), Okamoto K (2002), Song MS (2011), Huttlin EL (2015), Di Fiore B (2015), Pan ZQ (1993), Pan ZQ (1993), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	43
EP300	36	BAG6	2	affinity chromatography technology	Jiang W (2011)	1
CUL2	3	PCNA	0	affinity chromatography technology	Bennett EJ (2010)	1
CREBBP	29	STAT3	0	affinity chromatography technology, enzymatic study	Sun Y (2001), Yuan ZL (2005)	2
TP53	0	DOCK7	3	affinity chromatography technology	Fogeron ML (2013)	1
GADD45A	1	GADD45G	0	affinity chromatography technology	Kovalsky O (2001)	1
KAT2B	2	CDKN1B	1	pull down, affinity chromatography technology, pull down, enzymatic study	Perez-Luna M (2012), Perez-Luna M (2012), Perez-Luna M (2012), Perez-Luna M (2012)	4
TUBA1A	13	GAPDH	0	biochemical	Kristensen AR (2012)	1
TP53	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN1B	1	MAPK8	3	pull down, affinity chromatography technology, affinity chromatography technology	Chang TS (2003), Chang TS (2003), Chang TS (2003)	3
CDKN1A	1	DTL	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Abbas T (2008), Abbas T (2008), Nishitani H (2008), Kim DH (2010), Zhang L (2012), Abbas T (2008), Shibata E (2011)	7
CCND3	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
ESR1	0	STAT3	0	affinity chromatography technology	Wang LH (2001)	1
EP300	36	NPM1	0	enzymatic study	Swaminathan V (2005)	1
TK1	0	CDK4	2	two hybrid	Vinayagam A (2011)	1
PIM1	2	CDC20	1	affinity chromatography technology, enzymatic study	Cen B (2010), Cen B (2010)	2
CCND3	1	CDKN1A	1	two hybrid, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Rual JF (2005), Datta NS (1998), Chen J (1996), Ramachandran N (2004), Wang J (2011), Fogeron ML (2013), Lodewick J (2013), Rolland T (2014), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017)	12
BCCIP	1	CDK2	0	affinity chromatography technology	Ono T (2000)	1
CDKN1A	1	JUN	0	affinity chromatography technology, affinity chromatography technology	Selma Dagtas A (2010), Selma Dagtas A (2010)	2
CCND2	2	CDKN1A	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Kehn K (2004), Bao GC (2006), Chen J (1996), Fogeron ML (2013), Rolland T (2014), Huttlin EL (2015), Chen TC (2014), Huttlin EL (2017), Welcker M (1998)	10
CDK14	4	CCND3	1	two hybrid, affinity chromatography technology	Shu F (2007), Shu F (2007)	2
CCNE1	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK5	0	STUB1	4	affinity chromatography technology	Kim C (2016)	1
GADD45A	1	CDK1	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Zhan Q (1999), Jin S (2000), Jin S (2000), Yang Q (2000), Yang Q (2000), Vairapandi M (2002), Zhan Q (1999), Zhan Q (1999), Zhang Y (2009)	9
CDK3	0	RB1	2	enzymatic study, enzymatic study	Connell-Crowley L (1997), Ren S (2004)	2
CDKN1A	1	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abbas T (2008), Abbas T (2008), Nishitani H (2008), Fogeron ML (2013)	4
PCNA	0	CCNE1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDKN1A	1	CDK6	0	affinity chromatography technology, pull down, affinity chromatography technology	Selma Dagtas A (2010), Ramachandran N (2004), Huttlin EL (2017)	3
RNF144B	0	CDKN1A	1	affinity chromatography technology, pull down, affinity chromatography technology	Ng CC (2003), Ng CC (2003), Ng CC (2003)	3
CDK4	2	CCND1	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sugimoto M (1999), Sugimoto M (1999), Serrano M (1993), Lin J (2001), Taules M (1998), Cariou S (2000), Coleman KG (1997), Jose-Eneriz ES (2008), Jose-Eneriz ES (2008), Diehl JA (1997), Okabe H (2007), Bustany S (2011), Gladden AB (2003), Sweeney KJ (1997), Musgrove EA (1996), Vlach J (1996), Garcia-Morales P (2006), Bindra RS (2002), Ruas M (2007), Poon RY (1996), Ramachandran N (2004), Larrea MD (2009), Waaijers S (2013), Mallampalli RK (2013), Rolland T (2014), Chen TC (2014), Barbash O (2009), Datta D (2015), Hukkelhoven E (2012), Hukkelhoven E (2012), Ghiani C (2001), Ito H (2016), Huttlin EL (2017), Roessig L (2001), Qie S (2017)	35
STAT3	0	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakashima K (1999), Nakashima K (1999), Ray S (2002), Ray S (2002), Yuan ZL (2005), Yuan ZL (2005), Gupta M (2011), Wang R (2005), Gray MJ (2005), Hou T (2008), Kotla S (2015)	11
SKP2	2	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cen B (2010), Bashir T (2004), Kelly A (2014), Craney A (2016), Huttlin EL (2017)	5
KAT2B	2	CCNA2	1	affinity chromatography technology, pull down, enzymatic study	Mateo F (2009), Mateo F (2009), Mateo F (2009)	3
CREBBP	29	CCNE1	1	affinity chromatography technology	Wang A (2004)	1
CDK6	0	CCND3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Lin J (2001), Meyerson M (1994), Datta NS (1998), Bockstaele L (2006), Shu F (2007), Ramachandran N (2004), Varjosalo M (2013), Rolland T (2014), Huttlin EL (2015), Yu H (2011), Huttlin EL (2017)	11
TP53	0	CDK5	0	affinity chromatography technology, pull down, affinity chromatography technology	Lee JH (2007), Lee JH (2007), Lee JH (2007)	3
CCND3	1	CDKN1B	1	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Lin J (2001), Lin J (2001), Zhang Q (1999), Barnouin K (1999), Barnouin K (1999), Datta NS (1998), Vlach J (1996), Bockstaele L (2006), Bockstaele L (2006), Waaijers S (2013), Waaijers S (2013), Huttlin EL (2015), Huttlin EL (2017)	14
CDK1	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Radu M (2008), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CDK5	0	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Guidato S (1998), Varjosalo M (2013), Varjosalo M (2013), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	6
TK1	0	BAG6	2	two hybrid	Vinayagam A (2011)	1
CDC6	0	CCNA2	1	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Petersen BO (1999), Petersen BO (1999), Saha P (1998), Jiang W (1999)	4
CEBPA	0	MAPK8	3	pull down, affinity chromatography technology, enzymatic study	Trivedi AK (2007), Trivedi AK (2007), Trivedi AK (2007)	3
EP300	36	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Felzien LK (1999), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CKS1B	0	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology	Wang W (2003), Sitry D (2002), Zhou W (2009), Ooi LC (2013), Huttlin EL (2017)	5
NPM1	0	HDAC1	4	affinity chromatography technology	Liu H (2007)	1
MAPK14	0	JUN	0	enzymatic study	Thakur N (2014)	1
PIM1	2	SKP2	2	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Cen B (2010), Cen B (2010), Cen B (2010), Cen B (2010)	4
PCNA	0	MDM2	2	affinity chromatography technology, affinity chromatography technology	Groehler AL (2010), Banks D (2006)	2
EP300	36	JUN	0	pull down, biochemical, x-ray crystallography, affinity chromatography technology, pull down, enzymatic study, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Campbell KM (2002), Campbell KM (2002), Campbell KM (2002), Subbaramaiah K (2002), Duyndam MC (1999), Wang WM (2011), Deng WG (2004), Deng WG (2004), Cheng SE (2011), Cheng SE (2011), Kim BK (2014), Vries RG (2001), Deng WG (2003), Liu L (2017), Liu L (2017)	15
TSG101	1	CDKN1A	1	two hybrid, affinity chromatography technology	Oh H (2002), Oh H (2002)	2
CASP3	0	RB1	2	enzymatic study, enzymatic study	Lemaire C (2005), Fattman CL (2001)	2
CASP3	0	CDKN1A	1	enzymatic study, enzymatic study, enzymatic study, imaging technique	Levkau B (1998), Park JA (1998), Zhang Y (1999), Chen TC (2014)	4
GADD45A	1	GAPDH	0	two hybrid	Vinayagam A (2011)	1
CDK3	0	CCNE2	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Zariwala M (1998), Huttlin EL (2015), Huttlin EL (2017)	3
HDAC1	4	CCND1	1	affinity chromatography technology, imaging technique, affinity chromatography technology	Fu M (2005), Fu M (2005), Batra S (2010)	3
CDK5	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2017)	2
CDK3	0	AKT2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NPM1	0	RB1	2	affinity chromatography technology	Haindl M (2008)	1
CCND2	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ESR1	0	CDKN1A	1	pull down, pull down, pull down, affinity chromatography technology	Fritah A (2005), Maynadier M (2008), Maynadier M (2008), Kinyamu HK (2003)	4
CREBBP	29	JUN	0	pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, far western blotting	Sano Y (1998), Sano Y (1998), Merika M (1998), Duyndam MC (1999), Johnson J (2007), Yamaguchi K (2005), Tsai LN (2008), Arias J (1994)	8
EP300	36	MDM2	2	pull down, affinity chromatography technology, biochemical, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study	Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Matt T (2004), Wang X (2004), Gillotin S (2010), Kobet E (2000), Nihira NT (2017)	9
GADD45G	0	PCNA	0	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Azam N (2001), Azam N (2001), Azam N (2001), Nakayama K (1999)	4
CCNA2	1	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Huttlin EL (2015), Huttlin EL (2017)	3
CDKN1A	1	AKT2	1	affinity chromatography technology, pull down	Heron-Milhavet L (2006), Heron-Milhavet L (2006)	2
CDK2	0	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
GADD45A	1	BAG6	2	two hybrid	Vinayagam A (2011)	1
CCNB1	3	CKS1B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Hein MY (2015), Huttlin EL (2017)	3
CCND2	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
YWHAQ	0	TUBA1A	13	pull down	Meek SE (2004)	1
STAT3	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Zhang Q (2005), Yuan ZL (2005), Gupta M (2011), Zhi Y (2012), Zhi Y (2012)	5
KAT2B	2	CDK2	0	pull down, affinity chromatography technology, enzymatic study	Mateo F (2009), Mateo F (2009), Mateo F (2009)	3
TK1	0	DOCK7	3	two hybrid	Vinayagam A (2011)	1
BAG6	2	RNF126	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down	Rolland T (2014), Huttlin EL (2015), Hein MY (2015), OConnor HF (2015), Rodrigo-Brenni MC (2014), Rodrigo-Brenni MC (2014), Rodrigo-Brenni MC (2014), Huttlin EL (2017), Krysztofinska EM (2016), Krysztofinska EM (2016), Krysztofinska EM (2016)	11
CCNE1	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McKenzie PP (2003), Shanahan F (1999), Koff A (1992), Koff A (1992), Mayer C (2004), Connor MK (2003), Boudrez A (2000), Varshochi R (2005), Jeong JH (2010), Bustany S (2011), Yeh ES (2006), Hui S (2011), Kim J (2007), Kiviharju-af Haellstroem TM (2007), Abbas T (2007), Nishimura T (2005), Matsumoto Y (2004), Harwell RM (2004), Harwell RM (2004), Peiretti A (2003), Peiretti A (2003), Kim YB (2000), Manenti S (1999), Datta NS (1998), Sheaff RJ (1997), Higashi H (1996), Higashi H (1996), Musgrove EA (1996), Vlach J (1996), Grim JE (2008), Liu S (2009), Ciarallo S (2002), Desai D (1995), Baydoun HH (2010), Baydoun HH (2010), Chu I (2007), Chu I (2007), Levkau B (1998), Poon RY (1996), Zhao J (1998), Zhao J (1998), Larrea MD (2009), Varjosalo M (2013), Varjosalo M (2013), Chan HM (2001), So J (2015), Ungermannova D (2005), Song MS (2011), Huttlin EL (2015), Hein MY (2015), Lin CH (2015), Lin CH (2015), Davis RJ (2017), Huttlin EL (2017)	54
PCNA	0	CDC6	0	two hybrid	Saha P (1998)	1