Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
NAMPT 10135 TEGLARINAD CHLORIDE CHEMBL190412 inhibitor TdgClinicalTrial, ChemblInteractions, DrugBank

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
NAMPT rs1319501 C Antihypertensives efficacy no No association between this SNP and responsiveness to methyldopa or antihypertensives (methyldopa, nifedipine or hydralazine) was found in women who were pregnant, and either had preeclampsia or gestational hypertension. The authors note that when the T allele is combined in a haplotype with rs3801266 T allele this haplotype is associated with responsive to antihypertensive therapy (p=0.0123) Allele C is not associated with response to Antihypertensives in women with Pregnancy as compared to allele T. 27168100 1449165300
NAMPT rs3801266 C Antihypertensives efficacy no No association between this SNP and responsiveness to methyldopa or antihypertensives (methyldopa, nifedipine or hydralazine) was found in women who were pregnant, and either had preeclampsia or gestational hypertension. The authors note that when the T allele is combined in a haplotype with rs1319501 C allele this haplotype is associated with responsive to antihypertensive therapy (p=0.0123). Please note that alleles have been complemented to the plus chromosomal strand. Allele C is not associated with response to Antihypertensives in women with Pregnancy as compared to allele T. 27168100 1449165313