Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
CDH13	rs2116971	G	perphenazine	efficacy	yes	as measured by changes in PANSS-T (positive and negative syndrome scale total score), using a mixed model repeated measures approach. Examined 6789 SNPs - p-value of p< or equal to 5x10-4 was considered significant. Please note: the allele was reported as C (though this gene is found on the plus chromosomal strand). It was unclear whether the allele was associated with an increased or decreased response to drug.	Allele G is associated with response to perphenazine in people with Schizophrenia.	22920393	981238720
CDH13	rs3784943	AG + GG	amphetamine	efficacy	yes	The authors reported that "amphetamine (vs. placebo) effects were significantly greater on "Feel Drug" ratings (p < 0.05) and marginally greater on "Feel High" ratings and systolic blood pressure (p < 0.10) in G/A + G/G genotypes than A/A genotypes. The G allele was more common among Asian than other racial groups." Patients with the risk allele may have greater risk of psychostimulant abuse liability.	Genotypes AG + GG is associated with increased response to amphetamine as compared to genotype AA.	27771748	1448276164