Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
ABCC9 10060 MINOXIDIL CHEMBL802 ChemblInteractions
ABCC9 10060 GLYBURIDE CHEMBL472 modulator DrugBank 12145099, 16845255, 15023854, 17294036, 14672537
ABCC9 10060 SARAKALIM CHEMBL2104449 ChemblInteractions
ABCC9 10060 NAMINIDIL CHEMBL2105160 ChemblInteractions
ABCC9 10060 ADENOSINE TRIPHOSPHATE CHEMBL14249 DrugBank 16845255, 16829188, 16897043
ABCC9 10060 PINACIDIL HYDRATE CHEMBL1200338 ChemblInteractions

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
ABCC9 rs2307024 TT efavirenz metabolism/PK no ON EFV-containing therapy for >7 days, absence of interacting drugs, no co-infection, drug intake 12 hrs (+/- 3 hrs) before blood draw, reported medication adherence above 90%. Receive 600 mg EFV once daily. Alleles given as C and T, and reported in CAR (NR1I3 gene). Genotype TT is not associated with concentrations of efavirenz in people with HIV Infections. 26774523 1447680461
ABCC9 rs704212 T montelukast metabolism/PK yes This variant is associated with reduced area under the plasma concentration-time curve (AUC) of montelukast (13.7% reduction per copy of each minor allele, P=2.19 × 10-4). Allele T is associated with decreased concentrations of montelukast in healthy individuals as compared to allele C. 28940478 1449576525