Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
CDH2	rs17446819	CC	methadone	efficacy	yes	Association between SNP and response to methadone is not directly shown in the paper. Genotype AA is associated with increased concentrations of CDH2 in plasma and individuals with increased CDH2 levels had an improved response to methadone treatment (p=0.005).	Genotype CC is associated with increased response to methadone as compared to genotypes AA + AC.	28358908	1448995536
CDH2	rs8094439	AA	methadone	efficacy	yes	Association between SNP and response to methadone is not directly shown in the paper. Genotype AA is associated with increased concentrations of CDH2 in plasma and individuals with increased CDH2 levels had an improved response to methadone treatment (p=0.005).	Genotype AA is associated with increased response to methadone as compared to genotypes AG + GG.	28358908	1448995530