PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
EHMT2 4 HDAC2 1 affinity chromatography technology, affinity chromatography technology Bantscheff M (2011), Bantscheff M (2011) 2
CDYL 1 REST 3 affinity chromatography technology, pull down Mulligan P (2008), Mulligan P (2008) 2
CDYL 1 LAMP2 0 affinity chromatography technology Huttlin EL (2017) 1
HDAC1 4 MIER1 2 affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Ding Z (2003), Ding Z (2003), Ding Z (2003), Bantscheff M (2011), Joshi P (2013), Hein MY (2015), Huttlin EL (2017) 7
EHMT2 4 CTBP1 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Ueda J (2006), Kuppuswamy M (2008), Huttlin EL (2015), Huttlin EL (2017) 4
EZH2 4 HIST1H3A 3 enzymatic study, enzymatic study, affinity chromatography technology Martin C (2006), Cha TL (2005), Cha TL (2005) 3
SMARCA4 19 HDAC2 1 biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference Sif S (2001), Qiu Z (2008), Xu Z (2006), Pal S (2003), Battaglioli E (2002), Tando T (2010), Hang CT (2010), Shen JP (2017) 8
HIST3H3 0 MIER1 2 unspecified method Vermeulen M (2010) 1
EHMT2 4 26148 0 two hybrid, two hybrid Rual JF (2005), Rolland T (2014) 2
EZH2 4 HDAC1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical van der Vlag J (1999), van der Vlag J (1999), Caretti G (2004), Tong ZT (2012), Tong ZT (2012), Su L (2012), Su L (2012), Wan C (2015) 8
HIST1H3A 3 HDAC2 1 affinity chromatography technology, enzymatic study, pull down Nishioka K (2002), Gyoery I (2003), Li X (2014) 3
RBBP4 3 HDAC2 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology Zhang Y (2003), Hakimi MA (2003), Zhang Y (2002), Tong JK (1998), Sun JM (2007), Sun JM (2007), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Wan C (2015), Hauri S (2016) 14
CDYL 1 SUZ12 0 affinity chromatography technology Zhang Y (2011) 1
HIST1H3A 3 26148 0 bioid Lambert JP (2015) 1
HDAC2 1 SETDB1 3 affinity chromatography technology Yang L (2003) 1
CYBRD1 0 HDAC2 1 affinity chromatography technology Huttlin EL (2017) 1
EHMT2 4 WIZ 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Ueda J (2006), Ueda J (2006), Bantscheff M (2011), Hein MY (2015), Hauri S (2016) 5
EHMT2 4 HIST3H3 0 enzymatic study Shi Y (2003) 1
EZH2 4 HIST3H3 0 enzymatic study, enzymatic study, enzymatic study Sneeringer CJ (2010), Yap DB (2011), Cao Q (2014) 3
HIST1H2BA 0 EHMT2 4 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
MYC 2 HDAC2 1 affinity chromatography technology, affinity chromatography technology Koch HB (2007), Hwang IY (2012) 2
MIER2 0 EHMT2 4 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
HDAC1 4 HDAC2 1 biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology Hakimi MA (2002), Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Fischle W (2002), Johnson CA (2002), Fischle W (2001), Fischer DD (2002), Fischer DD (2002), Ashburner BP (2001), Zhang Y (1999), Tong JK (1998), Tong JK (1998), Hassig CA (1998), Hassig CA (1998), Zhang Y (1997), van der Vlag J (1999), van der Vlag J (1999), Noh EJ (2009), Noh EJ (2009), Galasinski SC (2002), Galasinski SC (2002), Galasinski SC (2002), He S (2005), Humphrey GW (2001), Park JH (2004), Park JH (2004), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Martinez FP (2012), Martinez FP (2012), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013), Schnur N (2007), Schnur N (2007), Oh YM (2009), Wan C (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017) 48
CDYL 1 MIER1 2 affinity chromatography technology, affinity chromatography technology Bantscheff M (2011), Huttlin EL (2017) 2
HDAC1 4 HIST3H3 0 enzymatic study, unspecified method Shi Y (2003), Vermeulen M (2010) 2
SMARCA4 19 HIST1H3A 3 pull down, pull down, pull down Lavigne M (2009), Lavigne M (2009), Kouskouti A (2005) 3
MIER2 0 WIZ 2 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
HIST1H2BA 0 HDAC2 1 pull down, affinity chromatography technology Li X (2014), Huttlin EL (2017) 2
EZH2 4 HDAC2 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical van der Vlag J (1999), van der Vlag J (1999), Tong ZT (2012), Tong ZT (2012), Wan C (2015) 5
CTBP1 2 HDAC2 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology Koipally J (2000), Glasspool RM (2005), Kuppuswamy M (2008), Kuppuswamy M (2008), Mendez LM (2008) 5
PLAUR 0 CDYL 1 affinity chromatography technology Huttlin EL (2015) 1
WIZ 2 CTBP1 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Ueda J (2006), Kuppuswamy M (2008), Huttlin EL (2015), Huttlin EL (2017) 4
CDYL 1 RBBP4 3 affinity chromatography technology Bantscheff M (2011) 1
TNF 0 FAS 2 affinity chromatography technology Legler DF (2003) 1
8339 0 EHMT2 4 bioid Lambert JP (2015) 1
CTBP1 2 CDYL 1 affinity chromatography technology Kuppuswamy M (2008) 1
APOM 0 CDYL 1 affinity chromatography technology Huttlin EL (2017) 1
HDAC2 1 MIER2 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Bantscheff M (2011), Huttlin EL (2015), Huttlin EL (2017) 3
LAMP2 0 RBBP4 3 biochemical Havugimana PC (2012) 1
HDAC1 4 MIER2 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Joshi P (2013), Huttlin EL (2015), Huttlin EL (2017) 3
HECW2 13 WIZ 2 affinity chromatography technology Lu L (2013) 1
BSG 1 CDYL 1 affinity chromatography technology Huttlin EL (2017) 1
CDYL 1 SMARCB1 1 affinity chromatography technology Mulligan P (2008) 1
HIST1H2BA 0 HDAC1 4 pull down, affinity chromatography technology, affinity chromatography technology Li X (2014), Huttlin EL (2015), Huttlin EL (2017) 3
ZNF644 6 EHMT2 4 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hauri S (2016) 2
8339 0 SUZ12 0 bioid Lambert JP (2015) 1
HDAC2 1 WIZ 2 affinity chromatography technology Bantscheff M (2011) 1
CDYL 1 HDAC1 4 affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Caron C (2003), Caron C (2003), Caron C (2003), Mulligan P (2008), Joshi P (2013), Hein MY (2015), Huttlin EL (2017) 7
HIST3H3 0 SUZ12 0 pull down Bartke T (2010) 1
EZH2 4 EHMT2 4 affinity chromatography technology Hein MY (2015) 1
WIZ 2 MIER1 2 affinity chromatography technology Hein MY (2015) 1
26148 0 CDYL 1 affinity chromatography technology Hein MY (2015) 1
HIST1H3A 3 CDYL 1 affinity chromatography technology, affinity chromatography technology Franz H (2009), Franz H (2009) 2
HIST1H3A 3 EHMT2 4 pull down, enzymatic study, enzymatic study Chin HG (2005), Chin HG (2005), Huang J (2010) 3
SMARCB1 1 RBBP4 3 biochemical Sif S (2001) 1
EHMT2 4 MIER1 2 affinity chromatography technology Bantscheff M (2011) 1
HECW2 13 CDYL 1 affinity chromatography technology Lu L (2013) 1
KLK6 2 CDYL 1 affinity chromatography technology Huttlin EL (2017) 1
HDAC2 1 SUZ12 0 biochemical, affinity chromatography technology, biochemical Havugimana PC (2012), Pasini D (2010), Wan C (2015) 3
HDAC2 1 HIST3H3 0 enzymatic study Shi Y (2003) 1
REST 3 SMARCA4 19 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Ooi L (2006), Battaglioli E (2002), Battaglioli E (2002) 3
8339 0 MIER1 2 bioid Lambert JP (2015) 1
HDAC1 4 EHMT2 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Joshi P (2013), Hein MY (2015), Huttlin EL (2017) 3
HIST3H3 0 RBBP4 3 affinity chromatography technology, unspecified method, unspecified method Campos EI (2010), Li X (2012), Vermeulen M (2010) 3
CDYL 1 WIZ 2 affinity chromatography technology, affinity chromatography technology Kuppuswamy M (2008), Hein MY (2015) 2
CD79A 2 CDYL 1 affinity chromatography technology Huttlin EL (2017) 1
SUZ12 0 26148 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Cao Q (2014), Huttlin EL (2017), Hauri S (2016) 3
BSG 1 NOP9 1 affinity chromatography technology Huttlin EL (2015) 1
CYBRD1 0 HDAC1 4 affinity chromatography technology Huttlin EL (2017) 1
REST 3 HDAC2 1 affinity chromatography technology Tahiliani M (2007) 1
EZH2 4 SUZ12 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Su IH (2005), Aoto T (2008), Hansen KH (2008), Li G (2010), Margueron R (2008), Margueron R (2008), Shen X (2008), Pasini D (2008), Pasini D (2008), Sarma K (2008), Xu B (2011), Xu B (2011), Avdic V (2011), Kaneko S (2010), Kaneko S (2010), Yap DB (2011), Lee ST (2011), Havugimana PC (2012), Sahasrabuddhe AA (2014), Wang L (2013), Wu L (2013), Pasini D (2010), Pasini D (2010), Pasini D (2010), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Wan C (2015), Hein MY (2015), Bhatnagar S (2014), Bhatnagar S (2014), Zhao R (2015), Wienken M (2016), Huttlin EL (2017), Zhang H (2016), Zhang H (2016), Mahara S (2016), Hauri S (2016), Hauri S (2016) 40
FAM136A 1 CDYL 1 affinity chromatography technology Huttlin EL (2017) 1
SETDB1 3 SUZ12 0 biochemical Wang H (2003) 1
SMARCB1 1 HDAC1 4 biochemical Sif S (2001) 1
CYBRD1 0 MIER2 0 affinity chromatography technology Huttlin EL (2017) 1
MYC 2 SMARCA4 19 affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe Ewing RM (2007), Park J (2002), Pal S (2003), Ivanov AA (2017) 4
MIER2 0 ZNF644 6 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
SMARCA4 19 RBBP4 3 biochemical Sif S (2001) 1
EFNB3 1 CDYL 1 affinity chromatography technology Huttlin EL (2017) 1
CYBRD1 0 MIER1 2 affinity chromatography technology Huttlin EL (2017) 1
SUZ12 0 HDAC1 4 affinity chromatography technology, biochemical Cao Q (2014), Wan C (2015) 2
CDYL 1 EZH2 4 affinity chromatography technology Zhang Y (2011) 1
CDYL 1 MIER2 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Bantscheff M (2011), Huttlin EL (2015), Huttlin EL (2017) 3
CYBRD1 0 CDYL 1 affinity chromatography technology Huttlin EL (2017) 1
HDAC1 4 CTBP1 2 pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology Zhang CL (2001), Melhuish TA (2000), Sundqvist A (1998), Jin W (2008), Joshi P (2013) 5
EZH2 4 RBBP4 3 affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Li G (2010), Kaneko S (2010), Kaneko S (2010), Cao Q (2014), Hein MY (2015), Hauri S (2016), Hauri S (2016) 7
CDYL 1 HDAC2 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Caron C (2003), Caron C (2003), Mulligan P (2008), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013) 6
NOP9 1 CDYL 1 affinity chromatography technology Hein MY (2015) 1
HIST1H2BA 0 MIER1 2 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
HDAC1 4 MYC 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Matsuoka Y (2008), Matsuoka Y (2008), Liu T (2007), Liu T (2007), Liu T (2007), Koch HB (2007), Hwang IY (2012), Hein MY (2015) 8
CTBP1 2 26148 0 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
SMARCB1 1 MYC 2 two hybrid, two hybrid, pull down, affinity chromatography technology, pull down Cheng SW (1999), Cheng SW (1999), Cheng SW (1999), Cheng SW (1999), Pal S (2003) 5
8339 0 CDYL 1 bioid Lambert JP (2015) 1
CTBP1 2 HIST3H3 0 enzymatic study Shi Y (2003) 1
SMARCB1 1 SMARCA4 19 biochemical, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, genetic interference, affinity chromatography technology, affinity chromatography technology Sif S (2001), Sullivan EK (2001), Wang W (1996), Wang W (1996), Otsuki T (2001), Zhao K (1998), Reyes JC (1997), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Pal S (2003), Bultman SJ (2005), Gong F (2008), Medjkane S (2004), Ito T (2008), Sif S (1998), Dallas PB (1998), Tando T (2010), Bakshi R (2010), Bakshi R (2010), Mahmoudi T (2006), Mahmoudi T (2006), Bartlett C (2011), Nishimoto N (2012), Havugimana PC (2012), Wan C (2015), Shen JP (2017), Pchelintsev NA (2013), Pchelintsev NA (2013) 30
SUZ12 0 HIST1H2BA 0 affinity chromatography technology Cao Q (2014) 1
CYBRD1 0 FAM136A 1 affinity chromatography technology Huttlin EL (2017) 1
CDYL 1 SMARCA4 19 affinity chromatography technology Mulligan P (2008) 1
EZH2 4 26148 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Cao Q (2014), Hein MY (2015), Hauri S (2016) 3
HDAC1 4 WIZ 2 affinity chromatography technology Huttlin EL (2017) 1
SUZ12 0 RBBP4 3 pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Cao R (2004), Cao R (2004), Havugimana PC (2012), Pasini D (2010), Cao Q (2014), Huttlin EL (2017), Hauri S (2016), Hauri S (2016) 8
HDAC1 4 SMARCA4 19 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference Qiu Z (2008), Battaglioli E (2002), Hang CT (2010), DiRenzo J (2000) 4
ZNF644 6 WIZ 2 affinity chromatography technology, affinity chromatography technology Hein MY (2015), Hein MY (2015) 2
HDAC1 4 REST 3 pull down, affinity chromatography technology Gocke CB (2008), Huang Y (1999) 2
SMARCB1 1 HDAC2 1 biochemical, biochemical Sif S (2001), Havugimana PC (2012) 2
NOP9 1 26148 0 affinity chromatography technology Hein MY (2015) 1
CDYL 1 EHMT2 4 affinity chromatography technology, pull down, affinity chromatography technology Mulligan P (2008), Mulligan P (2008), Bantscheff M (2011) 3
RBBP4 3 HDAC1 4 affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Zhang Y (2003), Yao YL (2003), Nicolas E (2001), Nicolas E (2001), Grozinger CM (1999), You A (2001), Hassig CA (1997), Hassig CA (1997), Ng HH (1999), Zhang Y (1999), Zhang Y (2002), Hassig CA (1998), Zhang Y (1997), Banach-Orlowska M (2009), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Humphrey GW (2001), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016) 35
HIST3H3 0 CDYL 1 unspecified method Vermeulen M (2010) 1
TNF 0 CDYL 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
HIST1H2BA 0 CDYL 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
MYC 2 CDYL 1 affinity chromatography technology Agrawal P (2010) 1
GLMP 0 CDYL 1 affinity chromatography technology Huttlin EL (2017) 1
SETDB1 3 HIST1H3A 3 enzymatic study, pull down Vandel L (2001), Binda O (2011) 2
FAS 2 CDYL 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
HDAC2 1 MIER1 2 affinity chromatography technology, affinity chromatography technology Bantscheff M (2011), Joshi P (2013) 2
HIST1H3A 3 RBBP4 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method Wysocka J (2006), Nishioka K (2002), Tagami H (2004), Foltz DR (2009), Millard CJ (2016) 5
HIST1H3A 3 HDAC1 4 affinity chromatography technology, pull down, affinity chromatography technology Nishioka K (2002), Li X (2014), Hein MY (2015) 3
CDYL 1 ZNF644 6 affinity chromatography technology, affinity chromatography technology Mulligan P (2008), Hein MY (2015) 2
REST 3 EHMT2 4 affinity chromatography technology, affinity chromatography technology Roopra A (2004), Roopra A (2004) 2
CDYL 1 SETDB1 3 affinity chromatography technology Mulligan P (2008) 1
SLC15A1 0 CDYL 1 affinity chromatography technology Huttlin EL (2017) 1
TNF 0 LAMP2 0 affinity chromatography technology Fritsch J (2014) 1