PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SPRY2	4	NR1H2	2	two hybrid	Vinayagam A (2011)	1
NCOR1	9	VDR	2	pull down, two hybrid, two hybrid, pull down, two hybrid, pull down, pull down	Puccetti E (2002), Tagami T (1998), Kim JY (2009), Kim JY (2009), Polly P (2000), Herdick M (2000), Herdick M (2000)	7
SUV39H1	0	KDM1A	2	two hybrid	Weimann M (2013)	1
HDAC4	10	SUV39H1	0	affinity chromatography technology	Zhang CL (2002)	1
MDFI	1	NR1H2	2	two hybrid, two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009), Rolland T (2014)	3
NR1H2	2	UBE2I	0	two hybrid	Albers M (2005)	1
KDM1A	2	CHD3	19	affinity chromatography technology, affinity chromatography technology	Wang Y (2009), Li Q (2011)	2
FOXO3	1	USP7	14	affinity chromatography technology, affinity chromatography technology	van der Horst A (2006), Bucur O (2014)	2
NR1H2	2	YY1	7	two hybrid	Wang J (2011)	1
RXRA	1	NCOA1	6	pull down, pull down, two hybrid, far western blotting, pull down, pull down, two hybrid, pull down, pull down, pull down, pull down, two hybrid, pull down	Jeyakumar M (1997), Yang W (2000), Shao G (2000), Shao G (2000), Mouchon A (1999), Herdick M (2000), Chan CM (2013), Kim HJ (1999), Flajollet S (2007), Monden T (1999), Kurtev V (2004), Osburn DL (2001), DiRenzo J (1997)	13
VDR	2	STAT1	1	affinity chromatography technology, pull down	Vidal M (2002), Vidal M (2002)	2
NCOR1	9	UBE2I	0	pull down, affinity chromatography technology	Tiefenbach J (2006), Tiefenbach J (2006)	2
NCOA6	6	NCOR2	12	two hybrid	Lee SK (2001)	1
NCOA6	6	VDR	2	two hybrid, pull down	Mahajan MA (2000), Mahajan MA (2000)	2
NR1H2	2	SENP3	1	affinity chromatography technology, affinity chromatography technology	Huang W (2011), Huang W (2011)	2
SIRT1	3	NCOR1	9	pull down, affinity chromatography technology	Hisahara S (2008), Hisahara S (2008)	2
NR1H2	2	CHD3	19	two hybrid	Vinayagam A (2011)	1
PIAS1	4	NR1H2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2012), Zhang Y (2012), Lee JH (2016)	3
MDFI	1	SPRY2	4	two hybrid	Rolland T (2014)	1
NCOR1	9	NCOA3	3	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Li X (2002), Li X (2002), Li X (2002), Li X (2002)	4
NR1H2	2	BAG6	2	two hybrid	Vinayagam A (2011)	1
DNMT3L	2	NR1H2	2	pull down	Pacaud R (2014)	1
NR1H2	2	STAT1	1	affinity chromatography technology	Lee JH (2016)	1
ABCA1	5	NR1H2	2	affinity chromatography technology, affinity chromatography technology	Mogilenko DA (2010), Mizuno T (2015)	2
VDR	2	RXRG	1	two hybrid, two hybrid	Ellison TI (2005), Albers M (2005)	2
NR1H2	2	HMGXB4	0	two hybrid	Vinayagam A (2011)	1
CHD3	19	VIM	0	two hybrid	Goehler H (2004)	1
VDR	2	CDKN1A	1	affinity chromatography technology	Thorne JL (2011)	1
NCOA6	6	RARA	5	two hybrid, two hybrid, pull down, pull down, two hybrid, pull down	Lee SK (2001), Lee SK (1999), Lee SK (1999), Ko L (2000), Mahajan MA (2000), Mahajan MA (2000)	6
RXRG	1	RXRA	1	affinity chromatography technology	Huttlin EL (2017)	1
NR1H2	2	NCOA1	6	two hybrid	Albers M (2005)	1
NCOA3	3	NR1H2	2	two hybrid, two hybrid	Albers M (2005), Albers M (2005)	2
SMARCA4	19	STAT1	1	imaging technique, affinity chromatography technology, affinity chromatography technology	Ni Z (2005), Cheng MB (2010), Zhang Y (2010)	3
NR1H2	2	SMARCA4	19	affinity chromatography technology	Huuskonen J (2005)	1
NR1H2	2	KDM1A	2	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
SIRT1	3	HDAC4	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao X (2005), Dehennaut V (2013), Dehennaut V (2013)	3
NCOA3	3	PIAS1	4	affinity chromatography technology, affinity chromatography technology	Li S (2012), Li S (2012)	2
NR1H2	2	ERG28	0	two hybrid	Vinayagam A (2011)	1
NCOA1	6	NCOA3	3	affinity chromatography technology, affinity chromatography technology	Lodrini M (2008), Lodrini M (2008)	2
RARA	5	MED1	4	affinity chromatography technology, pull down, fluorescent resonance energy transfe, two hybrid, x-ray crystallography	Llopis J (2000), Llopis J (2000), Llopis J (2000), Lee HK (2007), Rochel N (2011)	5
CDKN1A	1	FAF1	1	two hybrid	Vinayagam A (2011)	1
RARA	5	RXRG	1	two hybrid, two hybrid, two hybrid, two hybrid, two hybrid	Rual JF (2005), Albers M (2005), Wang J (2011), Rolland T (2014), Yu H (2011)	5
NRIP1	4	NR1H2	2	two hybrid	Albers M (2005)	1
CDKN1A	1	UBE2D1	0	two hybrid	Vinayagam A (2011)	1
NR1H2	2	CSAD	7	two hybrid	Vinayagam A (2011)	1
VDR	2	NR1H2	2	two hybrid	Albers M (2005)	1
VDR	2	RXRA	1	pull down, two hybrid, pull down, affinity chromatography technology, imaging technique, pull down, imaging technique, imaging technique, pull down, pull down, pull down, pull down, pull down, two hybrid, pull down, two hybrid, pull down, pull down, pull down, two hybrid, pull down, pull down, pull down, pull down, pull down, imaging technique, two hybrid, two hybrid, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology	Baudino TA (1998), Baudino TA (1998), Zhang C (2001), Song CS (2006), Dunlop TW (2005), Ting HJ (2005), Kim S (2005), Kim S (2005), Solomon C (2001), Liu YY (2000), Liu YY (2000), Rachez C (2000), Jimenez-Lara AM (1999), Yanagisawa J (1999), Yanagisawa J (1999), Yanagisawa J (1999), Ismail A (2004), Carvallo L (2008), Peleg S (2010), Albers M (2005), Herdick M (2000), Pedigo NG (2005), Hsieh JC (2003), Sorg BL (2006), Seuter S (2007), Seuter S (2007), Wang J (2011), Bartik L (2010), Rochel N (2011), Molnar F (2005), Ahmad K (2015), Ahmad K (2015)	32
RXRB	0	NR1H2	2	pull down, two hybrid, two hybrid	Feltkamp D (1999), Albers M (2005), Albers M (2005)	3
CDKN1A	1	CSAD	7	two hybrid	Vinayagam A (2011)	1
NR1H2	2	SCG5	1	two hybrid	Albers M (2005)	1
NR1H2	2	RMI1	0	two hybrid	Vinayagam A (2011)	1
NR1H2	2	SMPD1	3	two hybrid	Vinayagam A (2011)	1
VDR	2	MED1	4	affinity chromatography technology, imaging technique, imaging technique, pull down, pull down, affinity chromatography technology, pull down, pull down, two hybrid	Ito M (1999), Saramaeki A (2006), Vaeisaenen S (2005), Rachez C (2000), Carvallo L (2008), Rachez C (1999), Rachez C (1999), Yamamoto H (2003), Yamamoto H (2003)	9
NR0B2	1	RXRA	1	two hybrid, pull down, two hybrid	Lee YK (2000), Brendel C (2002), Wang J (2011)	3
HDAC4	10	NCOR2	12	pull down, pull down, affinity chromatography technology, pull down	Fischle W (2002), Huang EY (2000), Huang EY (2000), Torres-Padilla ME (2002)	4
NR1H2	2	COL4A5	2	two hybrid	Vinayagam A (2011)	1
NCOR1	9	CORO2A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yoon HG (2003), Yoon HG (2003), Yoon HG (2003), Yoon HG (2003), Huang W (2011)	5
CDKN1A	1	BAG6	2	two hybrid, two hybrid	Vinayagam A (2011), Wang J (2011)	2
HDAC4	10	NR1H2	2	enzymatic study, pull down	Ghisletti S (2007), Ghisletti S (2007)	2
NCOR2	12	RXRA	1	two hybrid, pull down, two hybrid, two hybrid	Tagami T (1998), Mouchon A (1999), Li H (1997), Albers M (2005)	4
NR1H2	2	TMEM161A	0	two hybrid	Albers M (2005)	1
PIAS1	4	PPARGC1B	2	affinity chromatography technology, affinity chromatography technology	Zhang Y (2012), Zhang Y (2012)	2
NRIP1	4	RXRA	1	pull down, pull down	Farooqui M (2003), LHorset F (1996)	2
NCOR1	9	NR1H2	2	two hybrid, two hybrid	Hu X (2003), Albers M (2005)	2
NCOR2	12	NR1H2	2	two hybrid, two hybrid, pull down	Albers M (2005), Albers M (2005), Johnson DR (2006)	3
NCOA3	3	NR0B2	1	two hybrid	Lee YK (2002)	1
PRKCA	7	NR1H2	2	enzymatic study	Delvecchio CJ (2008)	1
NCOR2	12	SMARCA4	19	biochemical	Li J (2000)	1
UBE2I	0	NCOR2	12	enzymatic study	Jiang J (2010)	1
NR1H2	2	FAF1	1	two hybrid	Vinayagam A (2011)	1
USP7	14	RARA	5	affinity chromatography technology, affinity chromatography technology, enzymatic study	Yang WC (2012), Yang WC (2012), Yang WC (2012)	3
RARA	5	NCOA3	3	pull down, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid	Torchia J (1997), Reineke EL (2007), Reineke EL (2007), Albers M (2005), Takeshita A (1997), Ferry C (2009), Gianni M (2006), Li CW (2010)	8
VDR	2	FOXO3	1	affinity chromatography technology, affinity chromatography technology, pull down	An BS (2010), An BS (2010), An BS (2010)	3
RARA	5	SUV39H1	0	affinity chromatography technology	Carbone R (2006)	1
NCOR2	12	CDKN1A	1	affinity chromatography technology	Thorne JL (2011)	1
ACVRL1	1	NR1H2	2	two hybrid, pull down, affinity chromatography technology	Mo J (2002), Mo J (2002), Mo J (2002)	3
NCOA3	3	RXRA	1	pull down, pull down, imaging technique, pull down, pull down	Chen H (1997), Lee WY (2002), Sinkkonen L (2005), Yang W (2000), Takeshita A (1997)	5
VDR	2	NR0B2	1	two hybrid	Albers M (2005)	1
NR1H2	2	FOXO3	1	two hybrid	Albers M (2005)	1
NR1H2	2	MPP1	1	two hybrid	Vinayagam A (2011)	1
HDAC4	10	YY1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ren G (2009), Ren G (2009), Han S (2006), Wang X (2008), Wang X (2008)	5
CDKN1A	1	COL4A5	2	two hybrid	Vinayagam A (2011)	1
UBE2I	0	STAT1	1	enzymatic study	Wu PY (2003)	1
NR1H2	2	SORBS2	2	two hybrid	Vinayagam A (2011)	1
HDAC4	10	STAT1	1	affinity chromatography technology	Stronach EA (2011)	1
UBE2I	0	CORO2A	2	enzymatic study	Nayak A (2014)	1
NR1H2	2	PDCD4	2	biochemical	Havugimana PC (2012)	1
RARA	5	NCOA1	6	pull down, pull down, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, two hybrid, pull down, pull down, pull down, pull down	Llopis J (2000), Llopis J (2000), Llopis J (2000), Mouchon A (1999), Torchia J (1997), Reineke EL (2007), Chan CM (2013), Kim HJ (1999), Flajollet S (2007), Cai SY (2010), DiRenzo J (1997)	11
NR1H2	2	RXRA	1	two hybrid, pull down, two hybrid	Seol W (1995), Seol W (1995), Albers M (2005)	3
HDAC4	10	NCOR1	9	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology	Fischle W (2002), Fischle W (2002), Fischle W (2002), Huang EY (2000), Huang EY (2000), Huang EY (2000), Wen YD (2000), Wen YD (2000), Joshi P (2013)	9
NR0B2	1	NR1H2	2	pull down, affinity chromatography technology	Brendel C (2002), Lee JH (2016)	2
NR1H2	2	PCDH17	4	two hybrid	Albers M (2005)	1
NCOA6	6	RXRA	1	pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, pull down, two hybrid, pull down, pull down	Lee SK (1999), Lee SK (1999), Lee SK (2001), Kong HJ (2003), Kong HJ (2003), Ko L (2002), Mahajan MA (2000), Mahajan MA (2000), Caira F (2000)	9
NCOR1	9	RXRA	1	pull down, pull down, pull down	Sun Y (2004), Herdick M (2000), Krogsdam AM (2002)	3
CDKN1A	1	NR1H2	2	two hybrid	Wang J (2011)	1
RARA	5	RXRB	0	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Rual JF (2005), Albers M (2005), Wang J (2011), Huttlin EL (2017)	4
ZXDC	1	NR1H2	2	two hybrid	Albers M (2005)	1
NR1H2	2	SIRT1	3	affinity chromatography technology	Li X (2007)	1
VDR	2	SIRT1	3	affinity chromatography technology, pull down	An BS (2010), An BS (2010)	2
RXRA	1	STAT1	1	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
UBE2I	0	HDAC4	10	enzymatic study, two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Knipscheer P (2008), Zhao X (2005), Zhao X (2005), Dehennaut V (2013), Tatham MH (2001), Knipscheer P (2007)	6
NR1H2	2	ING3	3	two hybrid	Albers M (2005)	1
CDKN1A	1	HDAC4	10	pull down	Garcia-Wilson E (2005)	1
NCOR2	12	VDR	2	pull down, two hybrid	Puccetti E (2002), Tagami T (1998)	2
RARA	5	SIRT1	3	affinity chromatography technology, pull down	Kang MR (2010), Kang MR (2010)	2
FAF1	1	BAG6	2	affinity chromatography technology	Baron Y (2014)	1
NCOR1	9	PIAS1	4	pull down, two hybrid, affinity chromatography technology	Tiefenbach J (2006), Tiefenbach J (2006), Tiefenbach J (2006)	3
NR1H2	2	VIM	0	two hybrid	Vinayagam A (2011)	1
NR1H2	2	NPY	0	two hybrid, two hybrid	Albers M (2005), Wang J (2011)	2
LAMC3	9	NR1H2	2	two hybrid	Wang J (2011)	1
PIAS1	4	NR0B2	1	affinity chromatography technology, affinity chromatography technology	Lee JH (2016), Lee JH (2016)	2
NCOR1	9	NCOA1	6	pull down	Stevens A (2003)	1
USP7	14	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Mungamuri SK (2016), Mungamuri SK (2016)	2
CORO2A	2	NR1H2	2	affinity chromatography technology, affinity chromatography technology	Huang W (2011), Huang W (2011)	2
NCOR1	9	SMARCA4	19	biochemical	Underhill C (2000)	1
HMGXB4	0	NCOR1	9	biochemical	Havugimana PC (2012)	1
PIAS1	4	STAT1	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Liao J (2000), Liao J (2000), Reardon C (2007), Reardon C (2007), Mowen KA (2001), Liu X (2008), Zhu W (2002), Liu B (1998), Chen TC (2014)	9
RARA	5	HDAC4	10	pull down	Franco PJ (2003)	1
NCOA6	6	MED1	4	pull down	Surapureddi S (2011)	1
NCOR2	12	NCOA3	3	affinity chromatography technology, pull down, pull down	Karmakar S (2010), Karmakar S (2010), Karmakar S (2010)	3
NCOA6	6	NCOA1	6	pull down, pull down, two hybrid, affinity chromatography technology	Surapureddi S (2011), Lee SK (1999), Lee SK (1999), Goo YH (2003)	4
RXRB	0	NCOA1	6	two hybrid	Albers M (2005)	1
NR0B2	1	SIRT1	3	pull down, affinity chromatography technology, affinity chromatography technology	Chanda D (2010), Chanda D (2010), Chanda D (2010)	3
NR0B2	1	RARA	5	pull down, two hybrid, pull down	Seol W (1996), Seol W (1998), Seol W (1998)	3
NCOR2	12	RXRG	1	two hybrid	Albers M (2005)	1
NR1H2	2	UBE2D1	0	two hybrid	Vinayagam A (2011)	1
RXRA	1	SMARCA4	19	affinity chromatography technology	Huuskonen J (2005)	1
NR1H2	2	SUV39H1	0	two hybrid	Weimann M (2013)	1
NCOA3	3	VDR	2	pull down, two hybrid, imaging technique, pull down, affinity chromatography technology, pull down	Leo C (2000), Bettoun DJ (2003), Vaeisaenen S (2005), Jimenez-Lara AM (1999), An BS (2010), Molnar F (2005)	6
NCOR1	9	CDKN1A	1	affinity chromatography technology	Thorne JL (2011)	1
SMARCA4	19	NCOA1	6	genetic interference	DiRenzo J (2000)	1
NR1H2	2	USP7	14	biochemical	Havugimana PC (2012)	1
RXRA	1	HDAC4	10	pull down	Franco PJ (2003)	1
NCOR2	12	RARA	5	affinity chromatography technology, pull down, pull down, far western blotting, two hybrid, pull down, two hybrid, pull down, pull down	Dong S (2002), Hong SH (1997), Mouchon A (1999), Li H (1997), Li H (1997), Reineke EL (2007), Albers M (2005), Dhordain P (1997), Johnson DR (2006)	9
VDR	2	RXRB	0	two hybrid, two hybrid	Albers M (2005), Wang J (2011)	2
SPRY2	4	KDM1A	2	two hybrid	Weimann M (2013)	1
SIRT1	3	CHD3	19	affinity chromatography technology	Kim JE (2008)	1
NCOR2	12	NCOR1	9	biochemical, two hybrid	Li J (2000), Korutla L (2005)	2
RXRA	1	MED1	4	imaging technique, pull down, two hybrid, two hybrid	Sinkkonen L (2005), Yang W (2000), Shao G (2000), Osburn DL (2001)	4
NR1H2	2	RXRG	1	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Albers M (2005), Vinayagam A (2011), Rolland T (2014), Huttlin EL (2017)	4
DNMT3L	2	RXRA	1	pull down	Pacaud R (2014)	1
RHOU	0	NR1H2	2	pull down	Dart AE (2015)	1
CDKN1A	1	VIM	0	two hybrid	Vinayagam A (2011)	1
DNMT3L	2	YY1	7	pull down	Pacaud R (2014)	1
UBE2I	0	CHD3	19	two hybrid	Lee BH (2003)	1
FOXO3	1	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	van der Horst A (2004), van der Horst A (2004), An BS (2010), An BS (2010), Tseng PC (2011), Brunet A (2004), Brunet A (2004), Brunet A (2004)	8
NCOA6	6	NR1H2	2	two hybrid, pull down, two hybrid	Lee SK (2001), Lee SK (2001), Albers M (2005)	3
MED1	4	NR1H2	2	two hybrid	Albers M (2005)	1
NR0B2	1	RXRG	1	pull down	Seol W (1996)	1
RXRB	0	NRIP1	4	pull down	Treuter E (1998)	1
BAG6	2	NPY	0	two hybrid	Wang J (2011)	1
VDR	2	NRIP1	4	two hybrid	Albers M (2005)	1
UBE2I	0	KDM1A	2	enzymatic study	Gocke CB (2005)	1
RXRA	1	RARA	5	pull down, biochemical, affinity chromatography technology, x-ray crystallography, far western blotting, two hybrid, imaging technique, pull down, two hybrid, x-ray crystallography, pull down, two hybrid, pull down, pull down, two hybrid, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology	Benkoussa M (2002), Bugge TH (1992), Wu Q (2004), Pogenberg V (2005), Li H (1997), Albers M (2005), Bellodi C (2006), Garcia-Fernandez LF (1998), Wang J (2011), Rochel N (2011), Rochel N (2011), Perlmann T (1995), Perlmann T (1995), DiRenzo J (1997), Martin PJ (2003), Martin PJ (2003), Chen TC (2014), Fujiu K (2005), Fujiu K (2005)	19
UBE2I	0	PIAS1	4	two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down	Lee BH (2003), Sapetschnig A (2002), Kahyo T (2001), Bandyopadhyay S (2010), Driscoll JJ (2010), Kahyo T (2001), Yin Y (2012), Gocke CB (2005), van den Akker E (2005), Ogawa H (2009), Schmidt D (2002), Gibbs-Seymour I (2015)	12
RARA	5	NCOR1	9	two hybrid, pull down, pull down, two hybrid, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, far western blotting, affinity chromatography technology, two hybrid, pull down, pull down, pull down	Dowell P (1999), Dowell P (1999), Guidez F (1998), Guidez F (1998), Li CW (2009), Loinder K (2004), Loinder K (2004), Minucci S (2000), Grignani F (1998), Grignani F (1998), DiRenzo J (1997), Zhu P (2006), Wang J (2011), Hoerlein AJ (1995), DiRenzo J (1997), DiRenzo J (1997)	16
RARA	5	NR1H2	2	two hybrid	Albers M (2005)	1
NR1H2	2	ROBO2	2	two hybrid	Vinayagam A (2011)	1
DUSP12	1	NR1H2	2	two hybrid	Vinayagam A (2011)	1
VDR	2	NCOA1	6	pull down, pull down, pull down, pull down, pull down, two hybrid, two hybrid, pull down, two hybrid, pull down	Solomon C (2001), Liu YY (2000), Jimenez-Lara AM (1999), Carvallo L (2008), Herdick M (2000), Chan CM (2013), Albers M (2005), Yamamoto H (2003), Yamamoto H (2003), DiRenzo J (1997)	10
RARA	5	NRIP1	4	affinity chromatography technology, pull down, pull down, pull down, pull down, two hybrid	Hu X (2004), Farooqui M (2003), LHorset F (1996), Zechel C (2002), Mouchon A (1999), Rolland T (2014)	6
SIRT1	3	UBE2I	0	enzymatic study	Hsieh YL (2013)	1
SIRT1	3	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Li Z (2009), Vaquero A (2007)	2
UBE2I	0	RXRA	1	enzymatic study	Ogawa H (2009)	1
NR1H2	2	PPARGC1B	2	affinity chromatography technology	Zhang Y (2012)	1