PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SMAD2	5	PAPPA	3	two hybrid	Colland F (2004)	1
SMAD1	0	SKIL	3	affinity chromatography technology	Mizuide M (2003)	1
SMAD4	9	ZMYM2	5	two hybrid	Colland F (2004)	1
SMAD1	0	PIAS4	5	two hybrid, affinity chromatography technology, two hybrid	Long J (2003), Long J (2003), Colland F (2004)	3
SMURF2	3	SNRNP70	2	two hybrid	Colland F (2004)	1
AES	2	SMAD3	1	two hybrid	Rolland T (2014)	1
SKIL	3	COL4A2	2	two hybrid	Colland F (2004)	1
MAP3K7	2	SKIL	3	affinity chromatography technology	Kajino T (2007)	1
HDAC1	4	ESR1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique	Kawai H (2003), Kawai H (2003), Varshochi R (2005), Varshochi R (2005), Kurtev V (2004), Liu XF (2004), Itoh Y (2007), Tarallo R (2011), Yoshimaru T (2013)	9
NCOR1	9	UBE2I	0	pull down, affinity chromatography technology	Tiefenbach J (2006), Tiefenbach J (2006)	2
SKIL	3	PSMC2	2	two hybrid	Colland F (2004)	1
PIAS4	5	SMAD3	1	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Imoto S (2003), Long J (2003), Long J (2003), Long J (2003), Long J (2003), Long J (2003)	6
PML	7	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down	Alcalay M (1998), Alcalay M (1998), Alcalay M (1998)	3
LRP1	25	SNX17	0	pull down	Stockinger W (2002)	1
SKIL	3	USP25	0	two hybrid	Colland F (2004)	1
RNF4	1	PML	7	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, enzymatic study, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, protein complementation assay	Bruderer R (2011), Haekli M (2005), Percherancier Y (2009), Tatham MH (2008), Maroui MA (2012), Maroui MA (2012), Li YJ (2012), Kuo CY (2014), Kuo CY (2014), Weisshaar SR (2008), Sahin U (2014)	11
ESR1	0	UIMC1	4	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Yan J (2007), Yan J (2007), Yan J (2007), Yan J (2007)	4
SKIL	3	THSD7A	4	two hybrid	Colland F (2004)	1
SKIL	3	PML	7	affinity chromatography technology	Pan D (2009)	1
TRIM33	4	SMAD4	9	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Agricola E (2011), Fattet L (2013), Bellaye PS (2014), Xue J (2014), Xue J (2014), Wu Y (2017)	6
SNW1	0	XRCC6	3	affinity chromatography technology	Lleres D (2010)	1
SKIL	3	VPS28	2	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
NCOR1	9	SIN3A	13	pull down, affinity chromatography technology	Khan MM (2001), Farhana L (2007)	2
SKIL	3	THAP5	1	two hybrid	Colland F (2004)	1
PML	7	NCOR2	12	pull down, affinity chromatography technology	Khan MM (2001), Hong SH (2001)	2
ESR1	0	PIAS1	4	two hybrid	Kobayashi S (2004)	1
SKIL	3	PTPRF	9	two hybrid	Colland F (2004)	1
SMAD3	1	TDP2	2	two hybrid	Wang J (2011)	1
NEDD4	2	SMURF2	3	affinity chromatography technology, affinity chromatography technology	Kuratomi G (2005), Huttlin EL (2017)	2
PIAS3	2	SMAD4	9	affinity chromatography technology, pull down	Long J (2004), Long J (2004)	2
SKIL	3	ESR1	0	affinity chromatography technology, pull down	Band AM (2011), Band AM (2011)	2
UBE2I	0	SKI	3	pull down, affinity chromatography technology	Ding B (2012), Ding B (2012)	2
SMAD4	9	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Moren A (2003), Wotton D (1999), Mori N (2001), Wu JW (2002), Wu JW (2002), Nakao A (1997), Wicks SJ (2000), Wu JW (2001), Chen X (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Razani B (2001), Razani B (2001), Wang B (2008), Moren A (2005), Kurisaki K (2003), Prunier C (2003), Kato Y (2002), Xu J (2000), Wang L (2011), He W (2006), He W (2006), Dupont S (2009), Brown JD (1999), Pardali K (2000), Fu G (2011), Chen W (2007), Gao S (2009), Lin X (2003), Seo SR (2006), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Barrios-Rodiles M (2005), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Ali A (2013), Yamakawa N (2002), Yamakawa N (2002), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Zhou F (2017)	56
SNW1	0	MVP	1	affinity chromatography technology	Lleres D (2010)	1
SKIL	3	FZR1	1	affinity chromatography technology	Stroschein SL (2001)	1
TRIM62	4	SMAD3	1	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Chen N (2013), Chen N (2013), Chen N (2013), Chen N (2013)	4
SKIL	3	ZZEF1	5	two hybrid	Colland F (2004)	1
RNF111	2	SKI	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nagano Y (2007), Le Scolan E (2008), Erker Y (2013)	3
HDAC1	4	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Yao YL (2003), Yao YL (2003), Fleischer TC (2003), Fleischer TC (2003), Yang L (2003), Grozinger CM (1999), Zhang J (2002), Zhang J (2002), You A (2001), Zhang Y (1999), Zhang Y (2002), Tong JK (1998), Hassig CA (1998), Yasui D (2002), Huang EY (2000), Huang EY (2000), Kuzmichev A (2002), Kuzmichev A (2002), Martinowich K (2003), Martinowich K (2003), Suzuki M (2003), Suzuki M (2006), Nakamura T (2002), Wei Q (2005), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Skowyra D (2001), Humphrey GW (2001), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Oh YM (2009), Wan C (2015), Hein MY (2015), Hsu DS (2014), Huttlin EL (2017)	45
SKIL	3	RNF4	1	two hybrid	Colland F (2004)	1
SMAD2	5	NEDD4	2	affinity chromatography technology, affinity chromatography technology	Kuratomi G (2005), Kuratomi G (2005)	2
SMAD3	1	WWP1	3	affinity chromatography technology, affinity chromatography technology, two hybrid	Komuro A (2004), Seo SR (2004), Rolland T (2014)	3
SNW1	0	NCOR2	12	affinity chromatography technology, two hybrid, two hybrid	Zhou S (2000), Zhou S (2000), Leong GM (2004)	3
PML	7	TDG	0	affinity chromatography technology, pull down, imaging technique	Takahashi H (2005), Takahashi H (2005), Mohan RD (2007)	3
SMURF2	3	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang L (2013), Zhou F (2017), Zhou F (2017)	3
SKIL	3	TRAK1	7	two hybrid	Colland F (2004)	1
SNW1	0	SKIL	3	genetic interference	Leong GM (2001)	1
SNW1	0	SMAD2	5	genetic interference, two hybrid, pull down, affinity chromatography technology	Leong GM (2001), Leong GM (2001), Leong GM (2001), Brown KA (2008)	4
UBE2I	0	RB1	2	enzymatic study, pull down	Ledl A (2005), Ledl A (2005)	2
SKIL	3	CHD3	19	two hybrid	Colland F (2004)	1
RNF4	1	TDG	0	affinity chromatography technology, affinity chromatography technology	Hu XV (2010), Hu XV (2010)	2
SKI	3	SKIL	3	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Cohen SB (1999), Cohen SB (1999), Tan R (2006), He J (2003), Ikeuchi Y (2014)	5
SMAD1	0	SKI	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harada J (2003), Harada J (2003), Takeda M (2004), Mizuide M (2003)	4
UBE2I	0	HDAC1	4	enzymatic study	Citro S (2013)	1
MVP	1	AES	2	two hybrid	Corominas R (2014)	1
SKIL	3	EEF1G	0	two hybrid	Colland F (2004)	1
SMAD3	1	SVEP1	10	two hybrid	Colland F (2004)	1
SKIL	3	SPARCL1	3	two hybrid	Colland F (2004)	1
SMAD4	9	FBLN1	1	two hybrid	Colland F (2004)	1
SMAD2	5	WWP1	3	affinity chromatography technology, affinity chromatography technology	Komuro A (2004), Seo SR (2004)	2
SKI	3	RB1	2	affinity chromatography technology	Tokitou F (1999)	1
SKIL	3	NCOR2	12	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Nomura T (1999), Nomura T (1999), Nomura T (1999), Nomura T (1999), Nomura T (1999)	5
HDAC1	4	PML	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Khan MM (2001), Khan MM (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Morey L (2008), Kuo HY (2013), Kim YE (2015)	10
MAP3K7	2	SMAD3	1	imaging technique	Chen TC (2014)	1
SMAD3	1	TGFBR1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Yan X (2009), Tang Y (2003), Tang Y (2003), Herhaus L (2015)	4
SMAD2	5	SMURF2	3	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin X (2000), Lin X (2000), Bonni S (2001), Nakano A (2009), Komuro A (2004), Zhang Y (2001), Zhang Y (2001), Runyan CE (2009), Runyan CE (2009), Chong PA (2010), Brown KA (2008), Colland F (2004), Colland F (2004), Zhang Y (2017), Zhou F (2017), Zhou F (2017)	16
NCOR1	9	SKI	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Khan MM (2001), Tabata T (2009), Wu K (2003), He J (2003)	4
SMAD4	9	SKI	3	pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harada J (2003), Ueki N (2003), Wu JW (2002), Stroschein SL (1999), Tabata T (2009), Prunier C (2003), Prunier C (2003), Takeda M (2004), Takeda M (2004), Ferrand N (2010), Wu K (2003), Wu K (2003), Barrios-Rodiles M (2005), Colland F (2004), He J (2003), He J (2003), Jinnin M (2007), Li X (2015), Rashidian J (2015), Rashidian J (2015), Zhou F (2017)	21
SKIL	3	TSKU	1	two hybrid	Colland F (2004)	1
RNF111	2	SKIL	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Levy L (2007), Levy L (2007), Nagano Y (2007), Erker Y (2013)	4
LRP1	25	SNRNP70	2	two hybrid	Kajiwara Y (2010)	1
PIAS1	4	PML	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Rabellino A (2012), Rabellino A (2012), Rabellino A (2012)	3
MVP	1	ESR1	0	affinity chromatography technology, pull down	Abbondanza C (1998), Abbondanza C (1998)	2
UBE2I	0	RNF111	2	two hybrid, two hybrid, two hybrid	Markson G (2009), Bandyopadhyay S (2010), Rolland T (2014)	3
UBE2I	0	USP25	0	enzymatic study, pull down	Meulmeester E (2008), Meulmeester E (2008)	2
UBE2I	0	PML	7	enzymatic study, pull down, enzymatic study, two hybrid, two hybrid, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, pull down	Knipscheer P (2008), Kim YE (2005), Satow R (2012), Duprez E (1999), Wang J (2011), Tatham MH (2003), Duprez E (1999), Gocke CB (2005), Lin DY (2006), Jo S (2016), Schilling EM (2017)	11
RNF111	2	SMAD3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Koinuma D (2003), Yuzawa H (2009), Yuzawa H (2009), Levy L (2007), Erker Y (2013), Le Scolan E (2008)	6
SMAD3	1	HEYL	1	two hybrid	Colland F (2004)	1
SKIL	3	SKIL	3	pull down	Cohen SB (1999)	1
SKIL	3	XRCC6	3	two hybrid	Colland F (2004)	1
CBX4	1	RB1	2	genetic interference, affinity chromatography technology	Dahiya A (2001), Dahiya A (2001)	2
TGFBR1	2	SMAD2	5	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Razani B (2001), Faresse N (2008), Bai Y (2004), Tang Y (2003), Tang Y (2003), Ding L (2009), Lu D (2013), Herhaus L (2015)	8
SKIL	3	HEY1	2	two hybrid	Colland F (2004)	1
SKIL	3	TPM2	2	two hybrid	Colland F (2004)	1
RNF111	2	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Levy L (2007), Erker Y (2013), Le Scolan E (2008)	3
ESR1	0	XRCC6	3	affinity chromatography technology	Ju BG (2006)	1
ZMYM2	5	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gocke CB (2008), Joshi P (2013), Hein MY (2015), Huttlin EL (2017)	4
ESR1	0	TDG	0	pull down, pull down, affinity chromatography technology	Chen D (2003), Chen D (2003), Chen D (2003)	3
SMAD3	1	SMURF2	3	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin X (2000), Lin X (2000), Bonni S (2001), Nakano A (2009), Komuro A (2004), Zhang Y (2001), Zhang Y (2001), Tang LY (2011), Brown KA (2008), Zhang L (2013), Li Y (2017), Zhang Y (2017)	12
SMAD4	9	UBE2I	0	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, two hybrid	Rual JF (2005), Chang CC (2005), Lin X (2003), Colland F (2004), Wang J (2011), Wang J (2011)	6
UBE2I	0	PIAS3	2	two hybrid, two hybrid	Bandyopadhyay S (2010), Wang J (2011)	2
SKIL	3	OIP5	1	two hybrid	Rolland T (2014)	1
SKIL	3	ZNF106	2	two hybrid	Colland F (2004)	1
SMAD3	1	HDAC1	4	two hybrid, pull down	Liberati NT (2001), Akiyoshi S (1999)	2
ESR1	0	SASH1	8	affinity chromatography technology	Okada M (2015)	1
SMAD3	1	CXXC5	1	two hybrid	Colland F (2004)	1
RB1	2	FZR1	1	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
SKIL	3	IL36RN	0	two hybrid	Colland F (2004)	1
SMAD2	5	TRIM33	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xi Q (2008), He W (2006), He W (2006), Xi Q (2011), Fattet L (2013)	5
RNF111	2	PML	7	affinity chromatography technology, two hybrid	Erker Y (2013), Woodsmith J (2012)	2
SNW1	0	EEF1G	0	affinity chromatography technology	Zhang C (2003)	1
SKIL	3	MACF1	12	two hybrid	Colland F (2004)	1
SMAD1	0	CAMSAP1	5	two hybrid	Colland F (2004)	1
UBE2I	0	TDG	0	enzymatic study, enzymatic study, enzymatic study	Knipscheer P (2008), Mohan RD (2007), Coey CT (2014)	3
AXIN1	1	SKIL	3	affinity chromatography technology	Koinuma D (2011)	1
SKIL	3	TDP2	2	two hybrid	Colland F (2004)	1
RNF4	1	ESR1	0	two hybrid	Moilanen AM (1998)	1
SMAD3	1	TRIM33	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Xi Q (2008), He W (2006), Xi Q (2011), Xue J (2014), Gao S (2009)	5
SNW1	0	SIN3A	13	pull down	Zhou S (2000)	1
SMAD2	5	SKI	3	pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harada J (2003), Luo K (1999), Tabata T (2009), Prunier C (2003), Prunier C (2003), Akiyoshi S (1999), Akiyoshi S (1999), Takeda M (2004), Inoue Y (2011), Ferrand N (2010), Chen W (2007), Brown KA (2008), He J (2003), Rashidian J (2015), Zhou F (2017)	15
SNW1	0	DRG1	1	affinity chromatography technology	Lleres D (2010)	1
SMAD1	0	SMAD4	9	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harada J (2003), Hanai J (1999), Lopez-Rovira T (2002), Kato Y (2002), Wang L (2011), Li L (2004), Hata A (1998), Barrios-Rodiles M (2005), Wu RY (1997), Wu RY (1997), Colland F (2004), Qiu T (2007), Yan X (2016), Zhou F (2017)	14
SMAD1	0	TTF2	4	two hybrid	Colland F (2004)	1
DRG1	1	STK16	1	two hybrid	Rolland T (2014)	1
SKIL	3	TTF2	4	two hybrid	Colland F (2004)	1
SIN3A	13	SKI	3	pull down, affinity chromatography technology, affinity chromatography technology	Khan MM (2001), Inoue Y (2011), Wu K (2003)	3
NCOR1	9	ESR1	0	pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, imaging technique	Huang HJ (2002), Ku TK (2007), Fujita T (2003), Fujita T (2003), Zhu P (2006), Yoshimaru T (2013)	6
SMURF2	3	RNF111	2	two hybrid	Colland F (2004)	1
SKIL	3	SETDB1	3	two hybrid	Colland F (2004)	1
SMAD1	0	WWP1	3	affinity chromatography technology, affinity chromatography technology	Komuro A (2004), Seo SR (2004)	2
SKIL	3	UIMC1	4	two hybrid	Colland F (2004)	1
RB1	2	HDAC1	4	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Dick FA (2000), Fuks F (2000), Puri PL (2001), Puri PL (2001), Wang S (2002), Luo RX (1998), Luo RX (1998), Lai A (1999), Lai A (1999), Ferreira R (1998), Kimura H (2003), Qiu Z (2008), Fedele M (2006), Brown VD (2002), Khan MM (2001), Dasgupta P (2004), Chang YC (2001), Dahiya A (2000), Zhang HS (2000), Tokitou F (1999), Nguyen DX (2004), Takaki T (2004), Magnaghi-Jaulin L (1998), Magnaghi-Jaulin L (1998), Brehm A (1998), Brehm A (1998), Brehm A (1998), Sun JM (2007), Fan LX (2012), Harbour JW (1999), Brehm A (1999), Joshi P (2013), Chen TT (2000), Chen TT (2000), Chen TT (2000), Chen TT (2000)	36
SKIL	3	CBX4	1	two hybrid	Colland F (2004)	1
SMAD3	1	SNRNP70	2	two hybrid	Colland F (2004)	1
SMAD3	1	HEY1	2	two hybrid	Colland F (2004)	1
SKIL	3	NID2	8	two hybrid	Colland F (2004)	1
SMAD3	1	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid	Brown KA (2008), Wu RY (1997), Wu RY (1997)	3
SKIL	3	NCOR1	9	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, two hybrid, affinity chromatography technology	Nomura T (1999), Nomura T (1999), Nomura T (1999), Nomura T (1999), Nomura T (1999), Colland F (2004), He J (2003)	7
UBE2I	0	NCOR2	12	enzymatic study	Jiang J (2010)	1
PML	7	SKI	3	affinity chromatography technology, pull down	Khan MM (2001), Khan MM (2001)	2
PSG3	2	FBLN1	1	affinity chromatography technology	Huttlin EL (2015)	1
WWP1	3	SKIL	3	affinity chromatography technology	Komuro A (2004)	1
SKIL	3	PIAS3	2	two hybrid	Colland F (2004)	1
SMAD3	1	PAPPA	3	two hybrid	Colland F (2004)	1
SMURF2	3	SKIL	3	affinity chromatography technology	Bonni S (2001)	1
SKIL	3	SVEP1	10	two hybrid	Colland F (2004)	1
SKIL	3	PPL	6	two hybrid	Colland F (2004)	1
UBE2I	0	ZNF106	2	two hybrid	Bandyopadhyay S (2010)	1
SIN3A	13	CHD3	19	affinity chromatography technology	Nakamura T (2002)	1
SKIL	3	PSG3	2	two hybrid	Colland F (2004)	1
MVP	1	SKIL	3	two hybrid	Corominas R (2014)	1
NID1	6	PTPRF	9	pull down	OGrady P (1998)	1
UBE2I	0	DRG1	1	enzymatic study	Jakobs A (2007)	1
SNW1	0	CHD3	19	affinity chromatography technology	Lleres D (2010)	1
SKIL	3	SRP72	5	two hybrid	Colland F (2004)	1
RNF4	1	MAP3K7	2	affinity chromatography technology, affinity chromatography technology	Tan B (2015), Tan B (2015)	2
SMURF2	3	TGFBR1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kavsak P (2000), Yan X (2011), Cai Y (2012), Cai Y (2012), Zhang L (2013), Chandhoke AS (2015), Hsu HY (2014)	7
SKIL	3	CHPF	1	two hybrid	Colland F (2004)	1
UBE2I	0	RNF4	1	two hybrid, two hybrid	Markson G (2009), Bandyopadhyay S (2010)	2
SMAD2	5	TRIM62	4	two hybrid	Colland F (2004)	1
RB1	2	SNW1	0	pull down, pull down	Prathapam T (2002), Prathapam T (2002)	2
RB1CC1	9	SKIL	3	affinity chromatography technology	Koinuma D (2011)	1
DRG1	1	SKIL	3	two hybrid	Rolland T (2014)	1
ING2	0	SMAD2	5	affinity chromatography technology	Sarker KP (2008)	1
SKIL	3	LRP1	25	two hybrid	Colland F (2004)	1
NCOR1	9	TRIM33	4	affinity chromatography technology	Yoon HG (2003)	1
SKIL	3	KRT81	1	two hybrid	Colland F (2004)	1
ESR1	0	DHX30	3	affinity chromatography technology	Tarallo R (2011)	1
SMAD4	9	SKIL	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stroschein SL (1999), Stroschein SL (1999), Barrios-Rodiles M (2005), Colland F (2004), Colland F (2004), He J (2003), He J (2003), Ikeuchi Y (2014), Jinnin M (2007), Li X (2015)	10
SKIL	3	TFPI2	0	two hybrid	Colland F (2004)	1
SKIL	3	FBLN1	1	two hybrid	Colland F (2004)	1
SKI	3	SMURF2	3	affinity chromatography technology	Zhou F (2017)	1
UBE2I	0	HIPK1	1	two hybrid	Bandyopadhyay S (2010)	1
SMAD3	1	ZBTB3	3	two hybrid	Ravasi T (2010)	1
SKIL	3	DHX30	3	two hybrid	Colland F (2004)	1
TRIM33	4	UBE2I	0	affinity chromatography technology, affinity chromatography technology	Fattet L (2013), Ikeuchi Y (2014)	2
SMAD1	0	HDAC1	4	affinity chromatography technology	Takeda M (2004)	1
SKIL	3	NID1	6	two hybrid	Colland F (2004)	1
SMAD1	0	PIAS1	4	two hybrid	Colland F (2004)	1
SNW1	0	SKI	3	two hybrid, pull down, two hybrid, pull down, affinity chromatography technology, genetic interference	Prathapam T (2001), Prathapam T (2001), Dahl R (1998), Dahl R (1998), Dahl R (1998), Leong GM (2001)	6
HDAC1	4	NCOR2	12	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Fischer DD (2002), Fischer DD (2002), Underhill C (2000), Wang L (2006)	4
WWP1	3	SMAD4	9	affinity chromatography technology	Seo SR (2004)	1
SKIL	3	TDG	0	two hybrid	Colland F (2004)	1
AES	2	STK16	1	two hybrid	Rolland T (2014)	1
ESR1	0	UBE2I	0	two hybrid, enzymatic study	Kobayashi S (2004), Sentis S (2005)	2
GLUL	2	HIPK1	1	two hybrid	Bandyopadhyay S (2010)	1
SKIL	3	SASH1	8	two hybrid	Colland F (2004)	1
SMAD3	1	SIN3A	13	pull down	Liberati NT (2001)	1
ING2	0	SKIL	3	affinity chromatography technology	Sarker KP (2008)	1
SMAD3	1	SMAD2	5	affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nakao A (1997), Lebrun JJ (1999), Dumont E (2003), Brown KA (2008), Brown KA (2008), Wu RY (1997), Wu RY (1997), Tang Y (2003), Tang Y (2003), Wang J (2011), Huttlin EL (2015), Huttlin EL (2017)	12
SNW1	0	SMAD4	9	genetic interference, two hybrid	Leong GM (2001), Leong GM (2001)	2
GLUL	2	PIAS3	2	two hybrid	Bandyopadhyay S (2010)	1
SIN3A	13	SETDB1	3	affinity chromatography technology	Yang L (2003)	1
RB1CC1	9	RNF111	2	affinity chromatography technology	Koinuma D (2011)	1
SMAD1	0	SNRNP70	2	two hybrid	Colland F (2004)	1
SKIL	3	ZNF200	0	two hybrid	Wang J (2011)	1
SETDB1	3	PML	7	affinity chromatography technology, affinity chromatography technology	Cho S (2011), Cho S (2011)	2
PML	7	SIN3A	13	pull down, affinity chromatography technology	Khan MM (2001), Khan MM (2001)	2
SKIL	3	CAMSAP1	5	two hybrid	Colland F (2004)	1
SMAD2	5	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wotton D (1999), Wotton D (1999), Takeda M (2004), Lo RS (2001)	4
PML	7	NCOR1	9	pull down, affinity chromatography technology, two hybrid, pull down	Khan MM (2001), Khan MM (2001), Khan MM (2001), Minucci S (2000)	4
NCOR1	9	PIAS1	4	pull down, two hybrid, affinity chromatography technology	Tiefenbach J (2006), Tiefenbach J (2006), Tiefenbach J (2006)	3
MAP3K7	2	SASH1	8	affinity chromatography technology	Dauphinee SM (2013)	1
HDAC1	4	TRAK1	7	affinity chromatography technology	Hein MY (2015)	1
SKIL	3	ZMYM2	5	two hybrid	Colland F (2004)	1
SMAD4	9	TDG	0	two hybrid	Colland F (2004)	1
SNW1	0	NCOR1	9	two hybrid, pull down, pull down	Leong GM (2004), Leong GM (2004), Leong GM (2004)	3
RB1CC1	9	SKI	3	affinity chromatography technology, affinity chromatography technology	Koinuma D (2011), Koinuma D (2011)	2
SKIL	3	FAF1	1	two hybrid	Colland F (2004)	1
AXIN1	1	SKI	3	affinity chromatography technology	Koinuma D (2011)	1
PIAS3	2	SMURF2	3	affinity chromatography technology, affinity chromatography technology	Chandhoke AS (2015), Chandhoke AS (2015)	2
AES	2	SKIL	3	two hybrid	Rolland T (2014)	1
SKIL	3	SNX17	0	two hybrid	Colland F (2004)	1
NCOR2	12	SIN3A	13	biochemical, pull down	Li J (2000), Huang EY (2000)	2
ZMYM2	5	PML	7	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Kunapuli P (2006), Kunapuli P (2006), Kunapuli P (2006), Guzzo CM (2014), Guzzo CM (2014)	5
SKI	3	TGFBR1	2	affinity chromatography technology, pull down	Ferrand N (2010), Ferrand N (2010)	2
SMAD3	1	XRCC6	3	two hybrid	Colland F (2004)	1
SMAD4	9	HDAC1	4	affinity chromatography technology	Takeda M (2004)	1
SKIL	3	ASCC3	12	two hybrid	Colland F (2004)	1
PIAS4	5	UBE2I	0	two hybrid, pull down, pull down, pull down	Wang J (2011), Yamamoto H (2003), Yin Y (2012), Ryu H (2010)	4
SKIL	3	TGFBR1	2	affinity chromatography technology	Ferrand N (2010)	1
MVP	1	RNF111	2	two hybrid	Corominas R (2014)	1
GLUL	2	PIAS1	4	two hybrid	Bandyopadhyay S (2010)	1
UBE2I	0	SETDB1	3	two hybrid	Bandyopadhyay S (2010)	1
PIAS4	5	SMAD2	5	affinity chromatography technology, two hybrid, affinity chromatography technology	Imoto S (2003), Long J (2003), Long J (2003)	3
NEDD4	2	DHX30	3	pull down	Ingham RJ (2005)	1
SMAD3	1	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Moren A (2003), Wu JW (2002), Nakao A (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Jablonska E (2010), Prunier C (2003), Kato Y (2002), Kaimori A (2010), Tang LY (2011), Tang LY (2011), Dupont S (2009), Dupont S (2009), Pardali K (2000), Kardassis D (2000), Xu L (2003), Fu G (2011), Chen W (2007), Kang JM (2012), Gao S (2009), Li H (2009), Li H (2009), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Dai F (2007), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Stroschein SL (1999), Stroschein SL (1999), Stroschein SL (1999), Wu RY (1997), Wu RY (1997), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Xue J (2014), Ali A (2013), Gao S (2009), Yamakawa N (2002), Yamakawa N (2002), Wang G (2005), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Yan X (2016), Wu Y (2017), Wu Y (2017)	60
SKIL	3	GOLGB1	8	two hybrid	Colland F (2004)	1
SMAD3	1	PML	7	affinity chromatography technology	Lin HK (2004)	1
SKI	3	ESR1	0	affinity chromatography technology	Band AM (2011)	1
PML	7	SMAD2	5	affinity chromatography technology	Lin HK (2004)	1
FBLN1	1	NID1	6	pull down, pull down, pull down	Adam S (1997), Tran H (1997), Pan TC (1993)	3
UBE2I	0	SMURF2	3	affinity chromatography technology	Chandhoke AS (2015)	1
SKIL	3	ZBTB3	3	two hybrid	Colland F (2004)	1
SNW1	0	SRP72	5	affinity chromatography technology	Lleres D (2010)	1
SKIL	3	TRIM33	4	affinity chromatography technology, affinity chromatography technology	Ikeuchi Y (2014), Ikeuchi Y (2014)	2
SKIL	3	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Stroschein SL (2001), Stroschein SL (1999), Tan R (2006), Mizuide M (2003), Brown KA (2008), Colland F (2004), Colland F (2004), He J (2003), Ikeuchi Y (2014)	9
NEDD4	2	SKIL	3	affinity chromatography technology	Kuratomi G (2005)	1
SNW1	0	SNRNP70	2	affinity chromatography technology	Lleres D (2010)	1
RPS27	0	SKIL	3	two hybrid	Wang J (2011)	1
SKIL	3	PIAS4	5	two hybrid	Colland F (2004)	1
HDAC1	4	CHD3	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tong JK (1998), Tong JK (1998), Kuzmichev A (2002), Sun JM (2007), Terhune SS (2010), Xue Y (1998), Xue Y (1998), Xue Y (1998), Havugimana PC (2012), Joshi P (2013), Hein MY (2015), Huttlin EL (2017)	12
SKIL	3	PLCD3	3	two hybrid	Colland F (2004)	1
SMAD3	1	SKIL	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stroschein SL (2001), Stroschein SL (2001), Stroschein SL (1999), Liberati NT (2001), Tan R (2006), Mizuide M (2003), Colland F (2004), He J (2003), Jinnin M (2007), Jinnin M (2007)	10
SMURF2	3	TFPI2	0	two hybrid	Colland F (2004)	1
SKIL	3	HIPK1	1	two hybrid	Colland F (2004)	1
FBLN1	1	SMAD3	1	two hybrid	Wang J (2011)	1
SKIL	3	SNRNP70	2	two hybrid	Colland F (2004)	1
SKIL	3	NXF3	1	two hybrid	Rolland T (2014)	1
SMAD1	0	NEDD4	2	affinity chromatography technology, two hybrid	Kim BG (2011), Colland F (2004)	2
ING2	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doyon Y (2006), Doyon Y (2006), Shi X (2006), Binda O (2008), Joshi P (2013), Huttlin EL (2017)	6
SMAD4	9	PIAS1	4	two hybrid, two hybrid	Colland F (2004), Wang J (2011)	2
TGFBR1	2	SMAD4	9	biochemical, affinity chromatography technology	Razani B (2001), Barrios-Rodiles M (2005)	2
SKI	3	MVP	1	affinity chromatography technology	Rashidian J (2015)	1
SKIL	3	TRIM62	4	two hybrid	Colland F (2004)	1
ING2	0	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doyon Y (2006), Doyon Y (2006), Shi X (2006), Huttlin EL (2017)	4
CHD3	19	PIAS4	5	two hybrid	Goehler H (2004)	1
UBE2I	0	ZMYM2	5	two hybrid	Bandyopadhyay S (2010)	1
SMAD2	5	SNRNP70	2	two hybrid	Colland F (2004)	1
ZMYM2	5	ZBTB3	3	two hybrid	Ravasi T (2010)	1
PIAS4	5	HDAC1	4	pull down	Gross M (2004)	1
SNW1	0	SMAD3	1	genetic interference, two hybrid, pull down, affinity chromatography technology	Leong GM (2001), Leong GM (2001), Leong GM (2001), Brown KA (2008)	4
SMAD1	0	SMURF2	3	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Lin X (2000), Lin X (2000), Komuro A (2004), Zhang Y (2001), Zhang Y (2001), Li L (2004), Chong PA (2010), Colland F (2004), Huttlin EL (2017), Zhou F (2017)	10
NCOR2	12	NCOR1	9	biochemical, two hybrid	Li J (2000), Korutla L (2005)	2
SNW1	0	PSMC2	2	affinity chromatography technology	Lleres D (2010)	1
SKIL	3	GLUL	2	two hybrid	Colland F (2004)	1
UBE2I	0	TDP2	2	two hybrid	Lee BH (2003)	1
PIAS4	5	SMAD4	9	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Imoto S (2003), Long J (2003), Long J (2003), Long J (2003), Lee PS (2003)	5
SKIL	3	EIF4G2	7	two hybrid	Colland F (2004)	1
SKIL	3	STK16	1	two hybrid	Rolland T (2014)	1
SKIL	3	PIAS1	4	two hybrid	Colland F (2004)	1
PML	7	AXIN1	1	affinity chromatography technology, affinity chromatography technology, pull down	Li Q (2011), Li Q (2011), Li Q (2011)	3
SKIL	3	RB1	2	affinity chromatography technology	Tokitou F (1999)	1
TGFBR1	2	MAP3K7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sorrentino A (2008), Kim SI (2009), Kim SI (2009), Zhang L (2013)	4
SMAD3	1	SKI	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harada J (2003), Ueki N (2003), Ueki N (2003), Tabata T (2009), Prunier C (2003), Liberati NT (2001), Akiyoshi S (1999), Akiyoshi S (1999), Takeda M (2004), Mizuide M (2003), Wu K (2003), Chen W (2007), Band AM (2009), Qin BY (2002), He J (2003), He J (2003), Jinnin M (2007), Jinnin M (2007), Rashidian J (2015)	19
SMAD4	9	NCOR1	9	affinity chromatography technology	He J (2003)	1
ESR1	0	NCOR2	12	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Smith CL (1997), Fleming FJ (2004), Karmakar S (2010), Karmakar S (2010), Fujita T (2003), Fujita T (2003)	6
SIN3A	13	ESR1	0	affinity chromatography technology, affinity chromatography technology	Ellison-Zelski SJ (2009), Zhu P (2006)	2
UBE2I	0	CHD3	19	two hybrid	Lee BH (2003)	1
GLUL	2	UBE2I	0	two hybrid	Bandyopadhyay S (2010)	1
SKIL	3	PYCR2	1	two hybrid	Colland F (2004)	1
SKIL	3	ZBTB6	0	two hybrid	Colland F (2004)	1
SKIL	3	CXXC5	1	two hybrid	Colland F (2004)	1
SKIL	3	UBE2I	0	two hybrid	Colland F (2004)	1
PIAS3	2	SMAD3	1	affinity chromatography technology, pull down	Long J (2004), Long J (2004)	2
SKIL	3	HDAC1	4	affinity chromatography technology	Nomura T (1999)	1
UBE2I	0	GOLGB1	8	two hybrid	Bandyopadhyay S (2010)	1
SMURF2	3	AXIN1	1	enzymatic study, affinity chromatography technology	Kim S (2010), Kim S (2010)	2
UBE2I	0	PIAS1	4	two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down	Lee BH (2003), Sapetschnig A (2002), Kahyo T (2001), Bandyopadhyay S (2010), Driscoll JJ (2010), Kahyo T (2001), Yin Y (2012), Gocke CB (2005), van den Akker E (2005), Ogawa H (2009), Schmidt D (2002), Gibbs-Seymour I (2015)	12
SKIL	3	HEYL	1	two hybrid	Colland F (2004)	1
ESR1	0	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Matsuda T (2001), Ito I (2010), Ito I (2010), Ito I (2010)	4
SMAD2	5	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid, fluorescent resonance energy transfe	Brown KA (2008), Wu RY (1997), Wu RY (1997), Ivanov AA (2017)	4
SKIL	3	MORC4	0	two hybrid	Colland F (2004)	1
SMAD3	1	ESR1	0	affinity chromatography technology	Ito I (2010)	1
PIAS3	2	SMAD2	5	affinity chromatography technology, pull down	Long J (2004), Long J (2004)	2
SMAD4	9	SNRNP70	2	two hybrid	Colland F (2004)	1
SMAD3	1	NEDD4	2	affinity chromatography technology, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down	Kuratomi G (2005), Persaud A (2009), Aragon E (2011), Aragon E (2011), Aragon E (2011), Aragon E (2011)	6
SKIL	3	SIN3A	13	affinity chromatography technology	Nomura T (1999)	1
FZR1	1	TRIM33	4	affinity chromatography technology	Sedgwick GG (2012)	1
SKIL	3	PAPPA	3	two hybrid	Colland F (2004)	1