Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
SELE 6401 BIMOSIAMOSE CHEMBL1215923 inhibitor TdgClinicalTrial, ChemblInteractions, TTD
SELE 6401 CARVEDILOL CHEMBL723 inhibitor DrugBank 15374848
SELE 6401 CHEMBL1234621 CHEMBL1234621 DrugBank 17139284, 17016423
SELE 6401 RIVIPANSEL CHEMBL3707446 antagonist ChemblInteractions

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
SELE rs3917412 CC capecitabine efficacy yes FOLFOX (54.4%) and CAPOX (45.6%) regimens. Measured as cumulative survival over 100 months since diagnosis. Genotype CC is associated with decreased response to capecitabine, fluorouracil, leucovorin and oxaliplatin in people with Colonic Neoplasms as compared to allele T. 24980946 1447521040