PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
FBXO25	1	ACTG1	5	affinity chromatography technology	Teixeira FR (2010)	1
VCP	6	RUVBL2	4	affinity chromatography technology	Fogeron ML (2013)	1
SMARCA4	19	5430	0	biochemical, biochemical, affinity chromatography technology, biochemical, imaging technique, affinity chromatography technology, affinity chromatography technology	Sif S (2001), Wang W (1996), Zhao K (1998), Reyes JC (1997), Ni Z (2005), Zhao LH (2005), Zhao LH (2005)	7
PRKN	1	VCP	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Imai Y (2003), Sarraf SA (2013), Huttlin EL (2017)	3
LMX1B	1	ACTB	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAP2	7	DHX9	3	biochemical	Kristensen AR (2012)	1
CBL	7	MYH9	19	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Valiya Veettil M (2011), Valiya Veettil M (2011), Valiya Veettil M (2011), Brehme M (2009)	4
VCP	6	IQGAP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Fogeron ML (2013), Itoh N (2017), Itoh N (2017), Itoh N (2017)	4
LRRK2	5	ACTB	8	affinity chromatography technology, pull down	Meixner A (2011), Meixner A (2011)	2
FBXO25	1	RUVBL1	2	affinity chromatography technology	Teixeira FR (2010)	1
SHC1	0	IQGAP1	1	affinity chromatography technology	Brehme M (2009)	1
ESR1	0	VCP	6	pull down	Nalvarte I (2010)	1
CARM1	0	SMARCA4	19	biochemical, affinity chromatography technology, pull down, far western blotting	Xu W (2004), Xu W (2004), Xu W (2004), Xu W (2004)	4
SMN1	0	ACTB	8	affinity chromatography technology, two hybrid	Fuller HR (2010), Vinayagam A (2011)	2
5430	0	ACTB	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Hofmann WA (2004), Hofmann WA (2004), Kukalev A (2005), Obrdlik A (2008), Obrdlik A (2008)	5
ERG	1	HNRNPU	12	affinity chromatography technology, affinity chromatography technology, pull down	Brenner JC (2011), Wang S (2014), Wang S (2014)	3
KAT2B	2	VHL	0	affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Ji W (2014)	2
SHC1	0	MYH9	19	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
CARM1	0	ACTB	8	biochemical, affinity chromatography technology	Xu W (2004), Xu W (2004)	2
SMARCE1	1	ACTB	8	affinity chromatography technology, affinity chromatography technology	Zhao K (1998), Kaeser MD (2008)	2
VCAM1	2	GRB2	2	affinity chromatography technology	Humphries JD (2009)	1
VCAM1	2	RUVBL2	4	affinity chromatography technology	Humphries JD (2009)	1
ACTB	8	SSH1	1	pull down, affinity chromatography technology	Niwa R (2002), Huttlin EL (2017)	2
GRB2	2	5430	0	two hybrid	Wang J (2008)	1
CFL1	0	CFL2	0	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
ESR1	0	MYH9	19	affinity chromatography technology	Tarallo R (2011)	1
VCAM1	2	DHX9	3	affinity chromatography technology	Humphries JD (2009)	1
RUVBL2	4	HNRNPU	12	affinity chromatography technology	Jeronimo C (2007)	1
5430	0	TAF11	0	biochemical, pull down, affinity chromatography technology	Scully R (1997), Scully R (1997), Hofmann WA (2004)	3
DSTN	0	VCP	6	biochemical	Havugimana PC (2012)	1
GRB2	2	VCP	6	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
RUVBL1	2	ACTB	8	affinity chromatography technology, biochemical, biochemical	Jeronimo C (2007), Havugimana PC (2012), Wan C (2015)	3
PRSS23	1	ACTG1	5	two hybrid	Stelzl U (2005)	1
ACTB	8	CFL2	0	two hybrid, affinity chromatography technology, two hybrid, two hybrid	Rual JF (2005), Rual JF (2005), Rolland T (2014), Yu H (2011)	4
PPP1CA	3	5430	0	enzymatic study	Kim YK (2002)	1
UBASH3B	4	MYH9	19	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
TP53	0	SMN1	0	affinity chromatography technology, pull down, two hybrid	Young PJ (2002), Young PJ (2002), Vinayagam A (2011)	3
LRRK2	5	ACTG1	5	affinity chromatography technology	Meixner A (2011)	1
MYH9	19	PPP1CA	3	affinity chromatography technology	Hein MY (2015)	1
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
CARM1	0	SMARCE1	1	biochemical, affinity chromatography technology	Xu W (2004), Xu W (2004)	2
IQGAP1	1	CFL2	0	affinity chromatography technology	Hein MY (2015)	1
KAT2B	2	HNRNPU	12	affinity chromatography technology, pull down, affinity chromatography technology	Obrdlik A (2008), Obrdlik A (2008), Obrdlik A (2008)	3
SNCA	0	ENC1	0	unspecified method	Woods WS (2007)	1
CARM1	0	ESR1	0	affinity chromatography technology	Yi P (2017)	1
ACTB	8	DSTN	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
PNMA1	0	ACTB	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ACTB	8	CAV1	0	affinity chromatography technology, imaging technique	Ji Y (2007), Luo X (2017)	2
SHC1	0	ACTB	8	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
TRAF3IP1	3	ACTB	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Guo CW (2010), Guo CW (2010), Guo CW (2010), Guo CW (2010)	4
VCP	6	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Yu CC (2013), Fogeron ML (2013)	3
NSMAF	5	ACTB	8	affinity chromatography technology, affinity chromatography technology, pull down	Haubert D (2007), Haubert D (2007), Haubert D (2007)	3
PNMA1	0	FAM107A	0	two hybrid	Rolland T (2014)	1
DHX9	3	HNRNPU	12	affinity chromatography technology, biochemical, affinity chromatography technology	Chu L (2012), Kristensen AR (2012), Hein MY (2015)	3
FBXO25	1	IQGAP1	1	affinity chromatography technology	Teixeira FR (2010)	1
ERBB2	6	DUSP19	0	two hybrid	Yao Z (2017)	1
SHC1	0	HNRNPU	12	affinity chromatography technology	Li J (2013)	1
PRKN	1	RUVBL2	4	affinity chromatography technology	Zanon A (2013)	1
MYH9	19	ACTG1	5	affinity chromatography technology	Hein MY (2015)	1
TRAF3IP1	3	MAP1A	1	affinity chromatography technology	Guo CW (2010)	1
GRB2	2	ACTB	8	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
CAP2	1	ACTG1	5	affinity chromatography technology, two hybrid	Hubberstey A (1996), Rolland T (2014)	2
PLG	3	ACTB	8	far western blotting, affinity chromatography technology, pull down	Dudani AK (2005), Dudani AK (2005), Dudani AK (2005)	3
UBASH3B	4	CORO1C	2	affinity chromatography technology	Brehme M (2009)	1
HNRNPU	12	MYH9	19	biochemical	Havugimana PC (2012)	1
5430	0	RUVBL2	4	biochemical, affinity chromatography technology	Havugimana PC (2012), Cloutier P (2017)	2
GRB2	2	PPP1CA	3	affinity chromatography technology	Bisson N (2011)	1
SNCA	0	ACTB	8	affinity chromatography technology, affinity chromatography technology	Jeannotte AM (2008), Jeannotte AM (2008)	2
ESR1	0	CFL1	0	two hybrid	Arroyo R (2015)	1
ACTG1	5	CFL2	0	two hybrid, affinity chromatography technology, two hybrid	Rual JF (2005), Rual JF (2005), Rolland T (2014)	3
ACTB	8	CAP2	1	two hybrid, affinity chromatography technology	Rolland T (2014), Huttlin EL (2017)	2
TP53	0	CORO1C	2	affinity chromatography technology	Horikawa I (2014)	1
FBXO25	1	ACTB	8	two hybrid, affinity chromatography technology, affinity chromatography technology	Teixeira FR (2010), Teixeira FR (2010), Teixeira FR (2010)	3
SMARCA4	19	ACTB	8	affinity chromatography technology, affinity chromatography technology, biochemical	Zhao K (1998), Xu YZ (2011), Nishimoto N (2012)	3
KAT2B	2	CARM1	0	affinity chromatography technology, affinity chromatography technology	Gao X (2010), Gao X (2010)	2
SMARCE1	1	BCL7C	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Kaeser MD (2008), Kaeser MD (2008), Wan C (2015), Huttlin EL (2017)	4
GRB2	2	ACTG1	5	affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Li J (2013)	2
UBASH3B	4	IQGAP1	1	affinity chromatography technology	Brehme M (2009)	1
UBASH3B	4	ACTG1	5	affinity chromatography technology	Li J (2013)	1
VCAM1	2	PPP1CA	3	affinity chromatography technology	Humphries JD (2009)	1
VCAM1	2	PFN1	0	affinity chromatography technology	Humphries JD (2009)	1
VCAM1	2	HNRNPU	12	affinity chromatography technology	Humphries JD (2009)	1
VCAM1	2	VCP	6	affinity chromatography technology, affinity chromatography technology	Humphries JD (2009), Braunstein I (2015)	2
ACTB	8	TAF11	0	affinity chromatography technology, affinity chromatography technology	Hofmann WA (2004), Hofmann WA (2004)	2
IQGAP1	1	SPTBN2	11	affinity chromatography technology	Hein MY (2015)	1
SHC1	0	RUVBL2	4	affinity chromatography technology	Brehme M (2009)	1
USP46	5	IQGAP1	1	affinity chromatography technology	Sowa ME (2009)	1
RUVBL1	2	KAT5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim JH (2007), Doyon Y (2004), Doyon Y (2004), Kim JH (2005), Jacquet K (2016), Huttlin EL (2017)	6
IQGAP1	1	RUVBL1	2	biochemical	Kristensen AR (2012)	1
CAV1	0	VCP	6	affinity chromatography technology, imaging technique, affinity chromatography technology, pull down	Kirchner P (2013), Kirchner P (2013), Chen SF (2013), Chen SF (2013)	4
ESR1	0	ACTB	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Ambrosino C (2010), Ambrosino C (2010), Ambrosino C (2010), Tarallo R (2011), Nalvarte I (2010)	5
SMARCE1	1	ESR1	0	affinity chromatography technology, pull down, pull down, pull down	Belandia B (2002), Belandia B (2002), Kiskinis E (2006), Flajollet S (2007)	4
KAT5	1	VHL	0	affinity chromatography technology, affinity chromatography technology	Roe JS (2011), Roe JS (2011)	2
USP46	5	ACTB	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GRB2	2	HNRNPU	12	affinity chromatography technology	Brehme M (2009)	1
DUSP19	0	CORO1C	2	affinity chromatography technology	Yadav L (2017)	1
ESR1	0	RUVBL1	2	affinity chromatography technology	Tarallo R (2011)	1
GRB2	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Skolnik EY (1993), Skolnik EY (1993), Puil L (1994), Satoh T (1996), Fixman ED (1996), Fixman ED (1996), Fixman ED (1996), Ishihara H (1997), Fournier E (1999), Ravichandran KS (1994), Lamprecht R (2002), Park RK (1999), Sakaguchi K (2001), Park RK (1999), Park RK (1999), Hallak H (2001), Yokote K (1994), Saci A (2002), Zhang S (1999), Lazar DF (1994), VanderKuur J (1995), Kanai M (1997), Spivak-Kroizman T (1994), Giordano V (1997), Drobot L (2005), Erdreich-Epstein A (1997), Takahashi Y (1999), Barber DL (1997), Ahn SC (2003), Odai H (1995), Panchamoorthy G (1996), Panchamoorthy G (1996), Brehme M (2009), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Zhang L (1999), Brizzi MF (1996), Brizzi MF (1996), Liu BA (2012), Bisson N (2011), Fukazawa T (1996), Bisson N (2011), Umehara H (2002), Oksvold MP (2001), Oksvold MP (2001), Li J (2013), Li J (2013), Ueno H (1995), Prigent SA (1996), Wills MK (2014), Rausch O (1997), Ho JM (2002), Ho JM (2002), Yu WM (2006), Klint P (1995)	57
COTL1	0	CFL1	0	biochemical	Wan C (2015)	1
ESR1	0	PFN1	0	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Kanaujiya JK (2013), Kanaujiya JK (2013), Kanaujiya JK (2013), Kanaujiya JK (2013)	4
GRB2	2	MAP2	7	pull down, pull down	Lim RW (2000), Zamora-Leon SP (2001)	2
TP53	0	KAT5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Legube G (2004), Tyteca S (2006), Tyteca S (2006), Kurash JK (2008), Cheng Z (2008), Cheng Z (2008), Cheng Z (2008), Tang Y (2006), Tang Y (2006), Tang Y (2006), Dai C (2013)	11
ACTB	8	NCF1	2	far western blotting, far western blotting, pull down	Tamura M (2000), Tamura M (2006), Tamura M (2006)	3
ENC1	0	ACTB	8	far western blotting, affinity chromatography technology	Liang XQ (2004), Liang XQ (2004)	2
KAT5	1	ESR1	0	affinity chromatography technology, two hybrid, affinity chromatography technology	Nakajima A (2007), Gaughan L (2001), Jeong KW (2011)	3
VCAM1	2	IQGAP1	1	affinity chromatography technology	Humphries JD (2009)	1
PPP1CA	3	RUVBL1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Huttlin EL (2015), Huttlin EL (2017), Yadav L (2017), Yadav L (2017)	4
KAT2B	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study	Jin Y (2002), Wang H (2008), Zhao Y (2006), Roe JS (2006), Perez RE (2010), Tang Y (2006), Zhao LY (2003), Liu L (1999), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Harrod R (2003), MacPartlin M (2005), Chen H (1999), Kang H (2009)	15
IQGAP1	1	CFL1	0	affinity chromatography technology	Hein MY (2015)	1
FBXO25	1	RUVBL2	4	affinity chromatography technology	Teixeira FR (2010)	1
NOS3	7	ACTB	8	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Ji Y (2007), Ji Y (2007), Ji Y (2007), Ji Y (2007)	4
ACTB	8	ACTB	8	two hybrid, affinity chromatography technology, pull down, two hybrid, two hybrid	Rual JF (2005), Rual JF (2005), Shartava A (1997), Rolland T (2014), Yu H (2011)	5
MAP2	7	ACTB	8	pull down, biochemical	Pedrotti B (1994), Pedrotti B (1994)	2
TPST1	4	ACTB	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CBL	7	ERBB2	6	pull down, affinity chromatography technology	Zhou P (2003), Bisaro B (2016)	2
VHL	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2006), Roe JS (2006), Lai Y (2011), Lai Y (2011)	5
MYH9	19	CFL2	0	affinity chromatography technology	Hein MY (2015)	1
GRB2	2	MAP1A	1	two hybrid	Bandyopadhyay S (2010)	1
ERBB2	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method	Schulze WX (2006), Bourguignon LY (2001), Olayioye MA (1998), Li X (2007), Li X (2007), Crovello CS (1998), Jones RB (2006)	7
KAT5	1	ACTB	8	affinity chromatography technology, biochemical, affinity chromatography technology	Kim J (2010), Ikura T (2000), Jacquet K (2016)	3
SSH1	1	DSTN	0	enzymatic study	Niwa R (2002)	1
TP53	0	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SHC1	0	RUVBL1	2	affinity chromatography technology	Brehme M (2009)	1
TP53	0	IQGAP1	1	affinity chromatography technology	Fogeron ML (2013)	1
SMN1	0	5430	0	affinity chromatography technology, affinity chromatography technology, pull down	Zhao DY (2016), Zhao DY (2016), Zhao DY (2016)	3
CBL	7	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Gesbert F (1998), Erdreich-Epstein A (1997), Wang Y (1999), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Brizzi MF (1996), Fukazawa T (1996)	9
RUVBL2	4	PPP1CA	3	affinity chromatography technology, affinity chromatography technology, bioid	Jeronimo C (2007), Yadav L (2017), Yadav L (2017)	3
PFN1	0	CFL1	0	biochemical	Wan C (2015)	1
TP53	0	CARM1	0	pull down	An W (2004)	1
FAM107A	0	ACTB	8	imaging technique, affinity chromatography technology	Mu P (2017), Mu P (2017)	2
PRKN	1	RUVBL1	2	affinity chromatography technology	Zanon A (2013)	1
ERBB2	6	SSH1	1	affinity chromatography technology	Yao Z (2017)	1
RUVBL1	2	ACTG1	5	affinity chromatography technology, biochemical	Jeronimo C (2007), Wan C (2015)	2
CTGF	1	ACTB	8	biochemical, pull down, affinity chromatography technology	Yosimichi G (2002), Yosimichi G (2002), Yosimichi G (2002)	3
RUVBL1	2	RUVBL2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, two hybrid, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ewing RM (2007), Jeronimo C (2007), Jeronimo C (2007), Puri T (2007), Rashid S (2009), Kim JH (2007), Kim JH (2007), McKeegan KS (2007), Lee JS (2010), Lee JS (2010), Cai Y (2007), Cai Y (2007), Ikura T (2000), Havugimana PC (2012), Venteicher AS (2008), Venteicher AS (2008), Bauer A (2000), Bauer A (2000), Bauer A (2000), Salzer U (1999), Izumi N (2010), Kristensen AR (2012), Rolland T (2014), Wan C (2015), Jeganathan A (2015), Huttlin EL (2017), Cloutier P (2017), Cloutier P (2017)	29
VHL	0	HNRNPU	12	affinity chromatography technology	Lai Y (2011)	1
PRKN	1	UBASH3B	4	pull down	Ikeda F (2007)	1
MYH9	19	SPTBN2	11	affinity chromatography technology	Hein MY (2015)	1
MAP1A	1	ACTB	8	pull down, biochemical	Pedrotti B (1994), Pedrotti B (1994)	2
DUSP19	0	ACTB	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBASH3B	4	HNRNPU	12	affinity chromatography technology	Li J (2013)	1
SNCA	0	LRRK2	5	affinity chromatography technology, affinity chromatography technology	Qing H (2009), Qing H (2009)	2
GRB2	2	RUVBL1	2	affinity chromatography technology	Brehme M (2009)	1
ESR1	0	RUVBL2	4	affinity chromatography technology	Tarallo R (2011)	1
SHC1	0	CORO1C	2	affinity chromatography technology	Brehme M (2009)	1
MYH9	19	CORO1C	2	affinity chromatography technology	Hein MY (2015)	1
VCAM1	2	ACTB	8	affinity chromatography technology, affinity chromatography technology	Humphries JD (2009), Perez-Hernandez D (2013)	2
PRKN	1	SNCA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, genetic interference, affinity chromatography technology	Choi P (2001), Choi P (2001), Kawahara K (2008), Hampe C (2006), Nemes Z (2009), Oluwatosin-Chigbu Y (2003), Yang Y (2003), Norris KL (2015)	8
UBASH3B	4	CBL	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kowanetz K (2004), Kowanetz K (2004), Raguz J (2007), Hoeller D (2006), Peruzzi G (2007), Brehme M (2009)	6
SSH1	1	CORO1C	2	affinity chromatography technology	Li X (2016)	1
PRKN	1	TP53	0	pull down, enzymatic study	Jung YY (2017), Jung YY (2017)	2
VCP	6	ACTB	8	affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Fogeron ML (2013)	2
ESR1	0	CORO1C	2	affinity chromatography technology	Han SJ (2016)	1
IQGAP1	1	PPP1CA	3	affinity chromatography technology	Hein MY (2015)	1
KAT2B	2	PNMA1	0	two hybrid	Albers M (2005)	1
TP53	0	HNRNPU	12	affinity chromatography technology	Fogeron ML (2013)	1
TP53	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology	Liu G (2000), Duong V (2007), Saxena R (2016)	3
BCL7C	0	SMARCA4	19	affinity chromatography technology, biochemical, affinity chromatography technology	Kaeser MD (2008), Wan C (2015), Huttlin EL (2017)	3
TP53	0	SMARCA4	19	pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee D (2002), Lee D (2002), Lee D (2002), Napolitano MA (2007), Guan B (2011), Oh J (2008)	6
KAT5	1	ACTG1	5	affinity chromatography technology	Kim J (2010)	1
ACTB	8	CFL1	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
KAT5	1	RUVBL2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doyon Y (2004), Cheng Z (2008), Jacquet K (2016), Huttlin EL (2017)	4
KAT2B	2	5430	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Cho H (1998), Cho H (1998), Obrdlik A (2008), Obrdlik A (2008)	4
VCAM1	2	CFL1	0	affinity chromatography technology	Humphries JD (2009)	1
COTL1	0	ACTG1	5	pull down	Provost P (2001)	1
ACTB	8	AMOT	6	pull down, affinity chromatography technology	Chan SW (2013), Chan SW (2013)	2
MYH9	19	DSTN	0	affinity chromatography technology	Hein MY (2015)	1
IQGAP1	1	ACTG1	5	affinity chromatography technology	Hein MY (2015)	1
SHC1	0	ACTG1	5	affinity chromatography technology	Li J (2013)	1
PRSS23	1	ACTB	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAGEA10	1	KAT2B	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GRB2	2	IQGAP1	1	affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Brehme M (2009)	2
ESR1	0	PPP1CA	3	affinity chromatography technology, pull down	Tarallo R (2011), Nalvarte I (2010)	2
COTL1	0	ACTB	8	pull down, pull down	Provost P (2001), Provost P (2001)	2
IQGAP1	1	CORO1C	2	affinity chromatography technology	Hein MY (2015)	1
ESR1	0	ERBB2	6	affinity chromatography technology	Yang Z (2004)	1
CBL	7	ACTB	8	affinity chromatography technology, affinity chromatography technology	Valiya Veettil M (2011), Brehme M (2009)	2
CAV1	0	NOS3	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Garcia-Cardena G (1996), Garcia-Cardena G (1996), Brouet A (2001), Ji Y (2007), Linton EA (2003), Linton EA (2003)	6
ERBB2	6	ACTB	8	affinity chromatography technology, imaging technique	Li LY (2011), Li LY (2011)	2
ACTB	8	HNRNPU	12	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Kukalev A (2005), Kukalev A (2005), Obrdlik A (2008), Obrdlik A (2008)	4
LRRK2	5	PRKN	1	affinity chromatography technology, affinity chromatography technology	Smith WW (2005), Smith WW (2005)	2
HNRNPU	12	5430	0	affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Kim MK (1999), Vizlin-Hodzic D (2011), Kukalev A (2005), Obrdlik A (2008), Obrdlik A (2008), Obrdlik A (2008)	6
ERG	1	ACTB	8	affinity chromatography technology, affinity chromatography technology, pull down	Brenner JC (2011), Wang S (2014), Wang S (2014)	3
TRAF3IP1	3	ACTG1	5	affinity chromatography technology	Guo CW (2010)	1
VHL	0	5430	0	affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology	Mikhaylova O (2008), Kuznetsova AV (2003), Kuznetsova AV (2003), Sun W (2017)	4
CBL	7	IQGAP1	1	affinity chromatography technology	Brehme M (2009)	1
MYH9	19	ACTB	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohlstedt K (2006), Hein MY (2015), Chiu HC (2012)	3
ACTB	8	ACTG1	5	two hybrid, two hybrid, two hybrid	Rual JF (2005), Rolland T (2014), Yu H (2011)	3
SPTBN2	11	ACTB	8	pull down, pull down	Mao B (2001), Holleran EA (2001)	2
VHL	0	ACTB	8	affinity chromatography technology, pull down	Lai Y (2011), Lai Y (2012)	2
RUVBL2	4	ACTG1	5	affinity chromatography technology, biochemical	Jeronimo C (2007), Wan C (2015)	2
VCAM1	2	CORO1C	2	affinity chromatography technology	Humphries JD (2009)	1
VCAM1	2	MYH9	19	affinity chromatography technology	Humphries JD (2009)	1
ACTB	8	CORO1C	2	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
SMARCA4	19	SMARCE1	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Wang W (1996), Zhao K (1998), Zhao K (1998), Hu K (2006), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Pal S (2003), Bultman SJ (2005), Battaglioli E (2002), ONeill DW (2000), Tando T (2010), Mak AB (2010), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	18
ERG	1	5430	0	affinity chromatography technology, pull down	Wang S (2014), Wang S (2014)	2
ACTG1	5	DSTN	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
CFL2	0	CAP2	1	two hybrid	Rolland T (2014)	1
BCL7C	0	ACTB	8	affinity chromatography technology, affinity chromatography technology	Kaeser MD (2008), Huttlin EL (2017)	2
ESR1	0	5430	0	affinity chromatography technology, imaging technique, imaging technique, pull down	Ambrosino C (2010), Zhang H (2006), Zhang H (2006), Nalvarte I (2010)	4
PRKN	1	ACTB	8	affinity chromatography technology, affinity chromatography technology	Zanon A (2013), Imai Y (2003)	2
RUVBL2	4	ACTB	8	affinity chromatography technology, biochemical, biochemical	Jeronimo C (2007), Havugimana PC (2012), Wan C (2015)	3
PFN1	0	ACTB	8	pull down, two hybrid	Nunoi H (1999), Du Y (2009)	2
KAT2B	2	ACTB	8	affinity chromatography technology, affinity chromatography technology	Obrdlik A (2008), Obrdlik A (2008)	2
ACTG1	5	CFL1	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
MYH9	19	IQGAP1	1	affinity chromatography technology	Hein MY (2015)	1
CORO1C	2	ACTG1	5	biochemical	Wan C (2015)	1
FBXO25	1	CFL1	0	affinity chromatography technology	Teixeira FR (2010)	1
SHC1	0	UBASH3B	4	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
BCL7C	0	CAP2	1	affinity chromatography technology	Huttlin EL (2017)	1
LRRK2	5	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Ho DH (2015), Ho DH (2015), Ho DH (2015)	3
FBXO25	1	MYH9	19	affinity chromatography technology	Teixeira FR (2010)	1
LRRK2	5	IQGAP1	1	affinity chromatography technology	Liu Z (2011)	1
PPP1CA	3	TP53	0	two hybrid	Colland F (2004)	1
CFL2	0	DSTN	0	two hybrid	Rolland T (2014)	1
CAV1	0	SNCA	0	pull down	Madeira A (2011)	1
TRAF3IP1	3	MYH9	19	affinity chromatography technology	Guo CW (2010)	1
MYH9	19	CFL1	0	affinity chromatography technology	Hein MY (2015)	1
ESR1	0	CAV1	0	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Schlegel A (2001), Schlegel A (2001), Ramirez CM (2009), Watson CS (2012)	4
SLC6A2	3	ACTB	8	affinity chromatography technology, affinity chromatography technology	Jeannotte AM (2008), Jeannotte AM (2008)	2
ERBB2	6	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid	Schulze WX (2006), Wong L (1999), Olayioye MA (1998), Crovello CS (1998), Jones RB (2006), Yao Z (2017)	6
SMN1	0	DHX9	3	pull down, affinity chromatography technology	Pellizzoni L (2001), Pellizzoni L (2001)	2
DHX9	3	5430	0	affinity chromatography technology, affinity chromatography technology	Tang W (2009), Fujita H (2003)	2
UBASH3B	4	ACTB	8	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
PRKN	1	AMOT	6	affinity chromatography technology	Zanon A (2013)	1
VCP	6	5430	0	affinity chromatography technology, affinity chromatography technology	He J (2017), He J (2017)	2
CFL1	0	CAP2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PRKN	1	HNRNPU	12	affinity chromatography technology	Zanon A (2013)	1
GRB2	2	MYH9	19	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Li J (2013)	2
IQGAP1	1	ACTB	8	affinity chromatography technology, imaging technique, affinity chromatography technology	Ikeda S (2005), Ikeda S (2005), Hein MY (2015)	3
HSD17B3	0	ACTB	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DUSP19	0	ACTG1	5	affinity chromatography technology	St-Denis N (2016)	1
MAGEA10	1	ACTB	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBASH3B	4	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), Li J (2013), Li J (2013)	3
SHC1	0	ESR1	0	affinity chromatography technology, pull down	Song RX (2002), Song RX (2002)	2
PPP1CA	3	ACTB	8	affinity chromatography technology, biochemical	Cid C (2007), Havugimana PC (2012)	2
SLC6A2	3	SNCA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jeannotte AM (2008), Jeannotte AM (2008), Wersinger C (2006), Wersinger C (2006)	4
TP53	0	ACTB	8	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
ESR1	0	DHX9	3	affinity chromatography technology, pull down	Tarallo R (2011), Nalvarte I (2010)	2
PPP1CA	3	CAV1	0	affinity chromatography technology, affinity chromatography technology, pull down	Li L (2003), Li L (2003), Li L (2003)	3
SMARCA4	19	ESR1	0	two hybrid, pull down	Ichinose H (1997), DiRenzo J (2000)	2
DHX9	3	ACTB	8	affinity chromatography technology, affinity chromatography technology	Tang W (2009), Tang W (2009)	2
CBL	7	CORO1C	2	affinity chromatography technology	Brehme M (2009)	1
TP53	0	MYH9	19	affinity chromatography technology	Horikawa I (2014)	1