PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
LNX1	7	GTF2E2	2	affinity chromatography technology	Lenihan JA (2017)	1
PTPN11	20	157927	0	two hybrid	Daakour S (2016)	1
STAT1	1	KIT	4	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique	Deberry C (1997), Deberry C (1997), Deberry C (1997), Deberry C (1997), Chen TC (2014)	5
TRIM25	5	EPHA1	5	affinity chromatography technology	Choudhury NR (2017)	1
ERBB2	6	JAK2	1	affinity chromatography technology	Ren Z (2002)	1
FBXW7	2	EPOR	3	genetic interference	Bailey ML (2015)	1
PTPN11	20	JAK1	6	pull down, enzymatic study, affinity chromatography technology	Yin T (1997), Yin T (1997), Lehmann U (2003)	3
KIT	4	PIK3R1	6	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	De Sepulveda P (1999), van Dijk TB (2000), Serve H (1994), Zhu MJ (2007), Zhu MJ (2007), Yokouchi M (1997), Chen TC (2014)	7
GAB3	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Wolf I (2002), Wolf I (2002)	2
INSR	9	JAK1	6	affinity chromatography technology	Le MN (2002)	1
SRC	2	GAB2	3	affinity chromatography technology	Zhao C (1999)	1
JAK2	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study	Olayioye MA (1999), Olayioye MA (1999), Jones RB (2006), He K (2013)	4
PTK2	2	JAK2	1	affinity chromatography technology, affinity chromatography technology	Zhu T (1998), Ryu H (2000)	2
CRK	0	FGFR1	2	imaging technique, affinity chromatography technology, pull down	Chen TC (2014), Larsson H (1999), Larsson H (1999)	3
PLCG2	11	GAB2	3	affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Boudot C (2002)	2
CBL	7	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tanaka Y (2008), Tanaka Y (2008), Hoff H (2007), Chernock RD (2001), Chernock RD (2001)	5
KIT	4	PIK3R2	3	two hybrid	De Sepulveda P (1999)	1
FGFR4	6	PTPN11	20	two hybrid	Yao Z (2017)	1
CTNNB1	30	HDAC6	0	affinity chromatography technology	Li Y (2008)	1
SRC	2	FYN	1	unspecified method, affinity chromatography technology, affinity chromatography technology	Pirozzi G (1997), Chen Y (2009), Huttlin EL (2017)	3
PTPN11	20	CDH5	2	affinity chromatography technology	Ukropec JA (2000)	1
CDC73	1	PAF1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rozenblatt-Rosen O (2005), Rozenblatt-Rosen O (2005), Nordick K (2008), Nordick K (2008), Kim J (2010), Mak AB (2010), Mak AB (2010), Takahashi A (2011), Takahashi A (2011), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Herr P (2015), Huttlin EL (2017)	16
PIK3R1	6	IRS1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology	Hadari YR (1992), Morrison KB (2002), Gual P (2003), Hamer I (2002), Bazuine M (2003), Tzatsos A (2006), Calegari VC (2005), Tzatsos A (2009), Liu BA (2012), Sung CK (1994), Ren W (2013), Sung CK (1998), Grossmann A (2015), Grossmann A (2015), Antonetti DA (1996), Luo M (2007), Luo M (2007)	17
CD274	2	PTPN11	20	affinity chromatography technology	Latchman Y (2001)	1
IL6ST	0	PTPN6	0	affinity chromatography technology	Bartoe JL (2000)	1
EGFR	5	LGALS3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guo HB (2009), Merlin J (2011), Foerster S (2013)	3
SOCS3	0	PRLR	0	affinity chromatography technology	Dif F (2001)	1
TRIM25	5	MAPK14	0	affinity chromatography technology	Choudhury NR (2017)	1
HDAC6	0	ERBB4	5	protein complementation assay	Deribe YL (2009)	1
SRC	2	EPOR	3	affinity chromatography technology	Liang K (2010)	1
PDGFRA	3	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAPK14	0	PTPN11	20	biochemical	Kristensen AR (2012)	1
ERBB2	6	CRK	0	unspecified method	Jones RB (2006)	1
PTK2B	6	BCAR1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Manie SN (1997), Anfosso F (2001), Astier A (1997), Takahashi T (2003)	4
NTRK1	1	EPHA2	3	affinity chromatography technology	Emdal KB (2015)	1
ERBB2	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Vogel W (1996)	5
PIK3R2	3	CRKL	1	far western blotting, affinity chromatography technology, affinity chromatography technology	Sattler M (1997), Sattler M (1997), Martelli MP (2001)	3
NTRK1	1	PDGFRB	8	affinity chromatography technology	Emdal KB (2015)	1
PTPN11	20	CAV1	0	affinity chromatography technology	Caselli A (2002)	1
PILRA	0	PTPN11	20	affinity chromatography technology	Fournier N (2000)	1
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
SIT1	1	FYN	1	affinity chromatography technology	Marie-Cardine A (1999)	1
PIK3R2	3	GAB2	3	affinity chromatography technology	Brehme M (2009)	1
EGFR	5	CRKL	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
KDR	4	CDH5	2	affinity chromatography technology	Zanetti A (2002)	1
ELAVL1	0	IQCB1	3	affinity chromatography technology	Abdelmohsen K (2009)	1
SLAMF1	2	IGF1R	5	affinity chromatography technology	Huttlin EL (2017)	1
CTNNB1	30	SRC	2	affinity chromatography technology	Xi Y (2013)	1
FSD1	3	EFHD2	2	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	IRS2	6	affinity chromatography technology	Emdal KB (2015)	1
PTPN11	20	SLN	0	two hybrid	Daakour S (2016)	1
ERBB3	3	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology	Schulze WX (2006), Jones RB (2006), Li J (2013)	3
RPIA	0	LNX1	7	two hybrid	Rual JF (2005)	1
PTPN11	20	MTPN	0	biochemical	Kristensen AR (2012)	1
CDH5	2	IQCB1	3	affinity chromatography technology	Huttlin EL (2017)	1
MPZL1	0	SRC	2	affinity chromatography technology	Zhao R (2002)	1
IL6ST	0	STAT3	0	affinity chromatography technology	Novotny-Diermayr V (2002)	1
STAT3	0	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Dallavalle C (2016), Dallavalle C (2016)	2
PIK3R1	6	FGFR2	6	affinity chromatography technology	Dufour C (2008)	1
LEO1	3	RTF1	3	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, genetic interference	Nordick K (2008), Kim J (2010), Havugimana PC (2012), Wan C (2015), Horlbeck MA (2018)	5
SRC	2	BCAR1	6	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Burnham MR (1999), Burnham MR (1999), Wei L (2002), Hsia DA (2003), Kovacic-Milivojevic B (2001), Donaldson JC (2000), Angers-Loustau A (1999), Cabodi S (2004), Modzelewska K (2006), Sawada Y (2006), Riggins RB (2006), Riggins RB (2006)	12
IRS2	6	JAK1	6	affinity chromatography technology	Johnston JA (1995)	1
FGFR2	6	FGFR1	2	affinity chromatography technology	Huttlin EL (2017)	1
GRASP	1	PTPN11	20	affinity chromatography technology	Hirose M (2004)	1
IRS1	7	SOCS3	0	affinity chromatography technology, affinity chromatography technology	Calegari VC (2005), Calegari VC (2005)	2
FBXW7	2	STAT3	0	affinity chromatography technology, affinity chromatography technology	Yao S (2017), Yao S (2017)	2
CRK	0	GAB1	3	affinity chromatography technology	Brehme M (2009)	1
ELAVL1	0	PTK2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
CBL	7	PIK3R2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Lin H (2001), Hartley D (1995), Feshchenko EA (2004), Alcazar I (2009), Brehme M (2009), Brehme M (2009), Grossmann A (2015)	7
VCAM1	2	STAT5B	3	affinity chromatography technology	Humphries JD (2009)	1
SRC	2	PDGFRB	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee CW (2007), Collin G (2007), Wu CY (2008)	3
PTK2B	6	FYN	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Ganju RK (1997), Katagiri T (2000), Qian D (1997), Qian D (1997), Marie-Cardine A (1999)	5
LGALS9	0	CTNNB1	30	affinity chromatography technology	Ewing RM (2007)	1
VCAM1	2	GRB2	2	affinity chromatography technology	Humphries JD (2009)	1
PTPN11	20	PTPN11	20	two hybrid, affinity chromatography technology	Harris CE (1999), Li X (2016)	2
ERBB2	6	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Scaltriti M (2009), Graus-Porta D (1997), Le XF (2005), Chen TC (2014), Ritch PS (2005)	5
OXCT1	1	MTPN	0	biochemical	Kristensen AR (2012)	1
PTPN11	20	SOCS3	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Lehmann U (2003), Lehmann U (2003), Schmitz J (2000), Orr SJ (2007)	4
CSF2RB	6	SOCS1	1	affinity chromatography technology	Bunda S (2013)	1
MAPK14	0	TCEAL1	3	affinity chromatography technology	Varjosalo M (2013)	1
ERBB2	6	STAT3	0	affinity chromatography technology, unspecified method	Ren Z (2002), Jones RB (2006)	2
NTRK1	1	STAT1	1	affinity chromatography technology	Emdal KB (2015)	1
CDC73	1	LEO1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Rozenblatt-Rosen O (2005), Rozenblatt-Rosen O (2005), Rozenblatt-Rosen O (2005), Nordick K (2008), Rozenblatt-Rosen O (2009), Mak AB (2010), Mak AB (2010), Takahashi A (2011), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017), Horlbeck MA (2018)	15
PTPN6	0	PLCG2	11	affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016)	2
CAV1	0	PDGFRA	3	affinity chromatography technology, biochemical, pull down	Yamamoto M (1999), Yamamoto M (1999), Yamamoto M (1999)	3
PILRA	0	PTPN6	0	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down	Fournier N (2000), Mousseau DD (2000), Mousseau DD (2000), Mousseau DD (2000)	4
INSR	9	PTPN11	20	pull down, affinity chromatography technology, pull down	Maegawa H (1994), Kharitonenkov A (1995), Kharitonenkov A (1995)	3
NTRK1	1	FASN	15	affinity chromatography technology	Emdal KB (2015)	1
JAK2	1	MAP3K5	1	affinity chromatography technology, enzymatic study	Yu L (2009), Yu L (2009)	2
CRK	0	SOCS1	1	pull down, two hybrid	De Sepulveda P (1999), Grossmann A (2015)	2
FGFR2	6	PTPN11	20	two hybrid	Yao Z (2017)	1
JAK2	1	SOCS3	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Sasaki A (2000), Sasaki A (2000), Sasaki A (1999), Sasaki A (1999), Sasaki A (1999), Masuhara M (1997), Masuhara M (1997), Monni R (2001), Haan S (2009), Babon JJ (2012), Calegari VC (2005), Calegari VC (2005), Varghese LN (2014), Kershaw NJ (2014)	14
ERBB4	5	PIK3R2	3	affinity chromatography technology	Schulze WX (2006)	1
STAT5A	4	JAK2	1	affinity chromatography technology, two hybrid, pull down, enzymatic study	Barahmand-Pour F (1998), Fujitani Y (1997), Fujitani Y (1997), Gouilleux F (1994)	4
ERBB4	5	GRB2	2	affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Kiuchi T (2014)	2
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
EGFR	5	PTPN6	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Tomic S (1995), Keilhack H (1998), Keilhack H (1998), Yao Z (2017)	4
NTRK1	1	GAB2	3	affinity chromatography technology	Emdal KB (2015)	1
FBXW7	2	BEX1	0	two hybrid	Arroyo R (2015)	1
FGFR1	2	PTPN11	20	affinity chromatography technology	Vecchione A (2007)	1
FGFR2	6	STAT5B	3	affinity chromatography technology, affinity chromatography technology	Cerliani JP (2011), Cerliani JP (2011)	2
ROS1	3	PTPN11	20	two hybrid	Keilhack H (2001)	1
ELAVL1	0	CRKL	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CBLB	3	PLCG2	11	affinity chromatography technology	Yasuda T (2002)	1
AATK	6	PTPN6	0	two hybrid	Yao Z (2017)	1
HDAC6	0	PTPN11	20	affinity chromatography technology	M L (2016)	1
NTRK1	1	OXCT1	1	affinity chromatography technology	Emdal KB (2015)	1
FLT1	4	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Zhao WD (2010), Zhao WD (2010)	2
ELAVL1	0	RPIA	0	affinity chromatography technology	Abdelmohsen K (2009)	1
JAK2	1	CSF2RB	6	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao Y (1995), Zhao Y (1995), Brizzi MF (1994), Lei JT (2011)	4
FGFR2	6	CBL	7	affinity chromatography technology	Kaabeche K (2004)	1
JAK1	6	STAT3	0	pull down, affinity chromatography technology, affinity chromatography technology	Ueda T (2002), Spiekermann K (2001), Andl CD (2004)	3
SOS1	5	FRS2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Foehr ED (2000), Wong A (2002), Kouhara H (1997), Lao DH (2006)	4
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
NTRK1	1	PIK3R2	3	affinity chromatography technology	Emdal KB (2015)	1
IRS1	7	PLCG2	11	unspecified method	Liu BA (2012)	1
JAK2	1	EPOR	3	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Huang LJ (2001), Huang LJ (2001), Witthuhn BA (1993), van den Akker E (2004)	4
GAB1	3	PTPN11	20	affinity chromatography technology, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Saito Y (2002), Rocchi S (1998), Ingham RJ (1998), Ingham RJ (1998), van den Akker E (2004), Kapoor GS (2004), Kapoor GS (2004), Kapoor GS (2010), Fan YX (2013)	9
TRIM25	5	ELAVL1	0	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
CSF3R	2	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Lochab S (2013), Lochab S (2013)	2
FBXW7	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology, pull down	Song Y (2017), Song Y (2017), Song Y (2017)	3
NTRK1	1	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Takahashi Y (2011), Emdal KB (2015), Emdal KB (2015)	3
TRIM25	5	CTNNB1	30	affinity chromatography technology	Choudhury NR (2017)	1
CRK	0	SOS1	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Okada S (1996), Okada S (1996), Okada S (1996), Ingham RJ (1996), Brehme M (2009), Chen TC (2014)	6
FGFR1	2	FRS2	0	pull down, affinity chromatography technology, two hybrid, pull down, two hybrid, x-ray crystallography, enzymatic study, affinity chromatography technology	Yan KS (2002), Ong SH (2000), Xu H (1998), Xu H (1998), Dhalluin C (2000), Dhalluin C (2000), Larsson H (1999), Vecchione A (2007)	8
TEK	2	PTK2	2	imaging technique	Moon HE (2015)	1
LRRK1	12	GAB2	3	affinity chromatography technology	Titz B (2010)	1
DDX58	3	PTPN11	20	affinity chromatography technology	Song Y (2017)	1
ELAVL1	0	ORMDL3	0	affinity chromatography technology	Abdelmohsen K (2009)	1
NTRK1	1	CDC73	1	affinity chromatography technology	Emdal KB (2015)	1
FGB	2	MAP2K1	8	affinity chromatography technology	Huttlin EL (2017)	1
FRS2	0	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ong SH (1996), Wong A (2002), Meakin SO (1999), Kouhara H (1997), Mason JM (2004), Liu BA (2012), Lao DH (2006), Bisson N (2011), Zhou L (2015)	9
KDR	4	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Seo DW (2003)	2
IRS1	7	CBLB	3	affinity chromatography technology	Suzue N (2006)	1
IRS2	6	GRB2	2	unspecified method, affinity chromatography technology	Liu BA (2012), Bisson N (2011)	2
PTPN11	20	SERF2	0	two hybrid	Daakour S (2016)	1
THEMIS	2	GRB2	2	affinity chromatography technology	Huttlin EL (2017)	1
OXCT1	1	PTPN11	20	biochemical	Kristensen AR (2012)	1
PIK3R1	6	INPP5D	2	affinity chromatography technology	Zhang S (1999)	1
PTK2B	6	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Haglund K (2004), Haglund K (2004), Sanjay A (2001), Schmidt MH (2003)	4
TREML1	1	PTPN6	0	affinity chromatography technology	Washington AV (2002)	1
EGFR	5	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid, pull down, protein complementation assay	Tong J (2009), Jones RB (2006), Foerster S (2013), Kotlyar M (2015), Gout I (1992), Petschnigg J (2014)	6
INSR	9	STAT5B	3	affinity chromatography technology	Le MN (2002)	1
EPOR	3	GRB2	2	pull down, pull down, affinity chromatography technology	Tauchi T (1995), Feng GS (1996), Barber DL (1997)	3
TREML1	1	PTPN11	20	affinity chromatography technology	Barrow AD (2004)	1
STAT3	0	CBL	7	two hybrid	Grossmann A (2015)	1
TRIM25	5	INSR	9	affinity chromatography technology	Choudhury NR (2017)	1
PDGFRB	8	STAT3	0	imaging technique	Chen TC (2014)	1
100499467	0	PTPN11	20	affinity chromatography technology	Zheng J (2016)	1
PTPN6	0	PIK3R1	6	two hybrid	Sathish JG (2001)	1
FRS2	0	NTRK1	1	pull down, two hybrid	Meakin SO (1999), Meakin SO (1999)	2
TRIM25	5	PLCG2	11	affinity chromatography technology	Choudhury NR (2017)	1
CBL	7	CD33	2	affinity chromatography technology	Walter RB (2008)	1
FLT1	4	KDR	4	enzymatic study, affinity chromatography technology	Autiero M (2003), Raikwar NS (2014)	2
JAK1	6	SOCS3	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down	Park ES (2000), Cohney SJ (1999), Cohney SJ (1999), Cohney SJ (1999)	4
DDX58	3	SRC	2	affinity chromatography technology	Johnsen IB (2009)	1
ERBB3	3	PTK2B	6	affinity chromatography technology	Verma N (2017)	1
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
PTPN11	20	FAM71E1	0	two hybrid	Daakour S (2016)	1
ELAVL1	0	MPZL1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
NTRK1	1	SYNCRIP	6	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	IRS1	7	unspecified method	Jones RB (2006)	1
IRS2	6	EPOR	3	affinity chromatography technology	Verdier F (1997)	1
VCAM1	2	PIK3R2	3	affinity chromatography technology	Humphries JD (2009)	1
CAV1	0	HDAC6	0	affinity chromatography technology	Li Y (2008)	1
MAP3K5	1	PTPN11	20	affinity chromatography technology, enzymatic study	Yu L (2009), Yu L (2009)	2
FBXW7	2	GSK3B	1	affinity chromatography technology	Kwon YW (2012)	1
PTPN11	20	STAT5A	4	pull down, enzymatic study, affinity chromatography technology	Yu CL (2000), Yu CL (2000), Chughtai N (2002)	3
FLT1	4	PTPN11	20	imaging technique	Chen TC (2014)	1
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
FGFR4	6	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
100499467	0	PRPF19	2	affinity chromatography technology	Zheng J (2016)	1
GRB2	2	BCAR1	6	affinity chromatography technology, pull down, affinity chromatography technology	Wang X (2000), Angers-Loustau A (1999), Ambrogio C (2005)	3
5175	0	INPP5D	2	pull down, far western blotting	Pumphrey NJ (1999), Pumphrey NJ (1999)	2
PTPN6	0	SIRPA	1	two hybrid, x-ray crystallography	Mousseau DD (2000), Yang J (2000)	2
NTRK1	1	CRKL	1	affinity chromatography technology	Emdal KB (2015)	1
STAT3	0	MPZL1	0	two hybrid	Grossmann A (2015)	1
LNX1	7	SRC	2	affinity chromatography technology, affinity chromatography technology, imaging technique	Weiss A (2007), Weiss A (2007), Weiss A (2007)	3
PIK3R2	3	PTPN11	20	affinity chromatography technology	Brehme M (2009)	1
SLAMF1	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Howie D (2002), Morra M (2001)	2
SIGLEC9	1	PTPN6	0	affinity chromatography technology	Yamaji T (2005)	1
CBLB	3	PTPN11	20	affinity chromatography technology	Hoff H (2007)	1
SOS1	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hadari YR (1998), Chin H (1997), Kapoor GS (2010), Yu WM (2006)	4
PTK2B	6	GRB2	2	affinity chromatography technology, affinity chromatography technology	Blaukat A (1999), Bruzzaniti A (2009)	2
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
PTPN11	20	BLZF1	0	two hybrid	Daakour S (2016)	1
CRKL	1	SOS1	5	affinity chromatography technology	Hein MY (2015)	1
PIK3R1	6	JAK2	1	pull down, genetic interference	Ren SY (2005), Shen JP (2017)	2
STAT5B	3	JAK2	1	affinity chromatography technology, two hybrid, enzymatic study	Barahmand-Pour F (1998), Fujitani Y (1997), Varghese LN (2014)	3
SNRNP27	0	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
PTK2	2	IRS1	7	two hybrid, affinity chromatography technology	Lebrun P (1998), Lebrun P (1998)	2
PTPN11	20	STAT1	1	two hybrid	Daakour S (2016)	1
IGF1R	5	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
LGALS3	0	FCGR2A	0	pull down	Cortegano I (2000)	1
LEO1	3	WDR61	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, genetic interference, genetic interference, genetic interference	Mak AB (2010), Wu J (2012), Wan C (2015), Hein MY (2015), Horlbeck MA (2018), Horlbeck MA (2018), Horlbeck MA (2018)	7
IGF1R	5	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IL4R	1	JAK1	6	pull down, affinity chromatography technology, affinity chromatography technology	Usacheva A (2002), Seki Y (2002), Huttlin EL (2017)	3
JAK1	6	IL6ST	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Haan C (2001), Haan C (2001), Kim H (1997), Haan C (2002)	4
FGFR1	2	SRC	2	affinity chromatography technology, affinity chromatography technology	Dudka AA (2010), Vecchione A (2007)	2
STAT3	0	FYN	1	pull down	Schreiner SJ (2002)	1
ELAVL1	0	EFHD2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
SLAMF6	2	PTPN11	20	affinity chromatography technology	Bottino C (2001)	1
ERBB2	6	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, far western blotting	Schroeder JA (2002), Bonvini P (2001), Schroeder JA (2002), Schroeder JA (2002), Kanai Y (1995), Kanai Y (1995)	6
TRIM25	5	CBL	7	affinity chromatography technology	Choudhury NR (2017)	1
CRKL	1	GAB1	3	affinity chromatography technology, affinity chromatography technology, imaging technique	Sakkab D (2000), Sakkab D (2000), Chen TC (2014)	3
NTRK1	1	CTR9	10	affinity chromatography technology	Emdal KB (2015)	1
RTF1	3	WDR61	0	affinity chromatography technology	Kim J (2010)	1
LRRK1	12	INPP5D	2	affinity chromatography technology	Titz B (2010)	1
FBXW7	2	DDX58	3	affinity chromatography technology, affinity chromatography technology	Song Y (2017), Song Y (2017)	2
TRIM32	2	DDX58	3	affinity chromatography technology	Zhang J (2012)	1
NTRK1	1	JAK1	6	affinity chromatography technology	Emdal KB (2015)	1
FCGR2A	0	CBL	7	biochemical	Marois L (2009)	1
STAT3	0	PIK3R1	6	two hybrid	Grossmann A (2015)	1
PDGFRA	3	CRK	0	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Yokote K (1998), Matsumoto T (2000), Matsumoto T (2000), Chen TC (2014)	4
GRB2	2	SOCS1	1	pull down	De Sepulveda P (1999)	1
CDC73	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down	Takahashi A (2011), Mosimann C (2006), Mosimann C (2006), Mosimann C (2006), Mosimann C (2006), Mosimann C (2006)	6
PDGFRA	3	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHRAC1	0	PTPN11	20	biochemical	Kristensen AR (2012)	1
ERBB3	3	CRK	0	unspecified method	Jones RB (2006)	1
CBL	7	TEK	2	affinity chromatography technology	Wehrle C (2009)	1
BCAR1	6	PTPN11	20	affinity chromatography technology	Manie SN (1997)	1
JAK2	1	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Chauhan D (1995), Chauhan D (1995), Giorgetti-Peraldi S (1995), Brizzi MF (1996)	4
LNX1	7	ORMDL3	0	two hybrid	Guo Z (2012)	1
MED21	1	FYN	1	affinity chromatography technology	Huttlin EL (2017)	1
SIGLEC11	0	PTPN6	0	affinity chromatography technology	Angata T (2002)	1
MPZL1	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Zhao ZJ (1998), Huttlin EL (2017)	2
IL4R	1	JAK2	1	affinity chromatography technology	Murata T (1996)	1
CD274	2	GSK3B	1	pull down, affinity chromatography technology	Li CW (2016), Li CW (2016)	2
HDAC6	0	IGF1R	5	genetic interference	Shen JP (2017)	1
INSR	9	JAK2	1	affinity chromatography technology, affinity chromatography technology	Maegawa H (1996), Le MN (2002)	2
GRB2	2	CSF3R	2	affinity chromatography technology, far western blotting, protein complementation assay, pull down, unspecified method	Ward AC (1998), Ward AC (1998), Erkeland SJ (2007), Kendrick TS (2004), Kendrick TS (2004)	5
PTK2	2	STAT3	0	affinity chromatography technology, imaging technique	Ryu H (2000), Chen TC (2014)	2
VCAM1	2	ELAVL1	0	affinity chromatography technology	Humphries JD (2009)	1
NTRK1	1	PAF1	6	affinity chromatography technology	Emdal KB (2015)	1
IQCB1	3	TRIM32	2	affinity chromatography technology, affinity chromatography technology, pull down	Das A (2017), Das A (2017), Das A (2017)	3
CTR9	10	RTF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Nordick K (2008), Kim J (2010), Kim J (2010), Havugimana PC (2012), Wan C (2015)	5
IL6ST	0	JAK2	1	affinity chromatography technology	Kim H (1997)	1
FGFR1	2	GAB1	3	affinity chromatography technology	Vecchione A (2007)	1
CBLB	3	PTK2B	6	affinity chromatography technology	Fan Y (2014)	1
PIK3R1	6	MAP3K5	1	affinity chromatography technology, affinity chromatography technology	Xie D (2009), Xie D (2009)	2
SRC	2	PTK2B	6	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Keely SJ (2000), Kumar S (1999), Dikic I (1996), Dikic I (1996), Bruzzaniti A (2009)	5
PTPN11	20	CTNNB1	30	affinity chromatography technology	Ukropec JA (2000)	1
ELAVL1	0	MTPN	0	affinity chromatography technology	Abdelmohsen K (2009)	1
IL6ST	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Lehmann U (2003), Anhuf D (2000), Kim H (1997), Schmitz J (2000)	4
CYP1A1	1	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PTK2	2	CXCR4	0	affinity chromatography technology	Wang J (2001)	1
CTR9	10	STAT3	0	affinity chromatography technology	Youn MY (2007)	1
CDH5	2	PTK2	2	affinity chromatography technology	Chang CC (2012)	1
DNM2	2	PDGFRA	3	affinity chromatography technology	Feng H (2012)	1
5175	0	PTPN11	20	affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Ilan N (2000), Pumphrey NJ (1999), Pumphrey NJ (1999), Hua CT (1998), Hua CT (1998), Jackson DE (1997), Jackson DE (1997)	7
ERBB2	6	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IL4R	1	PTPN11	20	pull down	Kashiwada M (2001)	1
PTPN11	20	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Boudot C (2002), Lynch DK (2002), Zhao C (1999), Crouin C (2001), Crouin C (2001), Schaeper U (2000), Cholay M (2010), van den Akker E (2004), Arnaud M (2004), Arnaud M (2004), Yu WM (2006), Yu WM (2006)	13
STAT5A	4	CBL	7	affinity chromatography technology, two hybrid	Dieudonne FX (2013), Grossmann A (2015)	2
GRB2	2	GAREM2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bisson N (2011), Taniguchi T (2013), Huttlin EL (2017)	3
PIK3R1	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang S (1999), Takahashi Y (1999), Craddock BL (1997), Wu CJ (2000), Wu CJ (2001), Yu WM (2006)	6
PTPN11	20	CTR9	10	affinity chromatography technology, bioid	Takahashi A (2011), St-Denis N (2016)	2
PTPN11	20	IRS1	7	pull down, affinity chromatography technology, unspecified method, pull down, enzymatic study	Kuhne MR (1993), Myers MG (1998), Liu BA (2012), Strack V (2002), Strack V (2002)	5
CBL	7	EPHA2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2002), Chakraborty S (2012), Walker-Daniels J (2002), Walker-Daniels J (2002), Dutta D (2013)	5
CRKL	1	PTPN11	20	affinity chromatography technology	Chin H (1997)	1
LGALS9	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MPIG6B	0	PTPN6	0	affinity chromatography technology	de Vet EC (2001)	1
CRKL	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Gesbert F (1998), Gelkop S (2001), Ren SY (2005)	3
EGFR	5	DNM2	2	affinity chromatography technology	Tong J (2014)	1
CTNNB1	30	GSK3B	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Davies G (2001), Kishida S (1999), Fischer L (2002), Kitagawa M (1999), Hart M (1999), Su Y (2008), Huang X (2009), Ding Q (2005), Piao S (2008), Varjosalo M (2013), Gao C (2014), Koo J (2015), Chen TC (2014), Lu D (2012), Kuslansky Y (2016), Novellasdemunt L (2017), Lu WJ (2015)	17
NTRK1	1	PTK2	2	affinity chromatography technology	Emdal KB (2015)	1
SRC	2	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olayioye MA (1999), Cirri P (1997), Chang YJ (2004), Chang YJ (2004)	4
FYN	1	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Tang H (1999), Chernock RD (2001)	2
GRB2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Bennett AM (1994), Ward AC (1998), Yin T (1997), Tang J (1997), Tang H (1999), Hadari YR (1998), Zhang S (1999), Wong L (1996), Brehme M (2009), Craddock BL (1997), Bisson N (2011), Blagoev B (2003), Bisson N (2011), Tauchi T (1995), Huttlin EL (2017), Kapoor GS (2010), Kapoor GS (2010), Vogel W (1996), Vogel W (1996), Yu WM (2006)	21
ELAVL1	0	MAP2K1	8	affinity chromatography technology	Abdelmohsen K (2009)	1
LGALS3	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FGFR1	2	ERBB3	3	unspecified method	Jones RB (2006)	1
ERBB2	6	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
EGFR	5	NOSIP	2	affinity chromatography technology	Yao Z (2017)	1
HDAC6	0	ERBB2	6	protein complementation assay	Deribe YL (2009)	1
KIT	4	STAT5B	3	enzymatic study	Jahn T (2007)	1
GHR	1	STAT5B	3	pull down, imaging technique	Yi W (1996), Chen TC (2014)	2
SRC	2	JAK2	1	affinity chromatography technology	Liang K (2010)	1
EGFR	5	IGF1R	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Morgillo F (2006), Riedemann J (2007), Riedemann J (2007)	3
FCGR2A	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
LEO1	3	CTNNB1	30	affinity chromatography technology	Mosimann C (2006)	1
PTK2	2	FYN	1	affinity chromatography technology, x-ray crystallography	Messina S (2003), Arold ST (2001)	2
PIK3R2	3	GHR	1	pull down	Moutoussamy S (1998)	1
NTRK1	1	CTNNB1	30	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	PTK2B	6	affinity chromatography technology, affinity chromatography technology	Keely SJ (2000), Ivankovic-Dikic I (2000)	2
SOCS1	1	ERBB2	6	unspecified method	Jones RB (2006)	1
FGFR1	2	SOS1	5	imaging technique	Chen TC (2014)	1
PTPN11	20	TRIM32	2	two hybrid, two hybrid	Rolland T (2014), Daakour S (2016)	2
EGFR	5	HDAC6	0	affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Gao YS (2010), Deribe YL (2009), Deribe YL (2009), Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	7
GRB2	2	PTPN6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Kon-Kozlowski M (1996), Saci A (2002)	3
THEMIS	2	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
ERBB2	6	GAB1	3	enzymatic study	Fan YX (2013)	1
FSD1	3	SRC	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRIM25	5	PTK2	2	affinity chromatography technology	Choudhury NR (2017)	1
CBL	7	PTPN6	0	affinity chromatography technology	Kant AM (2002)	1
CXCR4	0	PTPN6	0	affinity chromatography technology	Vila-Coro AJ (1999)	1
JAK2	1	PTK2B	6	affinity chromatography technology	Frank GD (2002)	1
KIT	4	GRB2	2	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down	De Sepulveda P (1999), Thoemmes K (1999), Feng GS (1996), Sun J (2007), Zhu MJ (2007), Wollberg P (2003), Brizzi MF (1996)	7
STAT5B	3	STAT3	0	imaging technique	Chen TC (2014)	1
NTRK1	1	DNM2	2	affinity chromatography technology	Emdal KB (2015)	1
IQCB1	3	PTPN11	20	affinity chromatography technology	Sang L (2011)	1
JAK1	6	GRB2	2	affinity chromatography technology, pull down	Kim H (2001), Giorgetti-Peraldi S (1995)	2
IL6ST	0	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Grant SL (2002), Grant SL (2002)	2
PDCD1	4	SOCS1	1	affinity chromatography technology	Zhang Y (2011)	1
SOCS1	1	IRS2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rui L (2002), Rui L (2002), McCormick SM (2016), McCormick SM (2016)	4
TRIM25	5	STAT3	0	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	IGF1R	5	affinity chromatography technology	Emdal KB (2015)	1
PDGFRA	3	CRKL	1	affinity chromatography technology, imaging technique	Yokote K (1998), Chen TC (2014)	2
FBXW7	2	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Jiang JX (2016), Jiang JX (2016)	2
NTRK1	1	SRSF10	0	affinity chromatography technology	Emdal KB (2015)	1
MED21	1	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
TRIM25	5	PTPN11	20	affinity chromatography technology	Choudhury NR (2017)	1
IRS2	6	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Argetsinger LS (1996), Verdier F (1997), Kim B (1998), Hamer I (2002), Calegari VC (2005), Tzatsos A (2009), Ren W (2013), Hein MY (2015)	8
CSF3R	2	FBXW7	2	affinity chromatography technology	Lochab S (2013)	1
CBL	7	MAPK14	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Erdreich-Epstein A (1997), Shen M (2009), Shen M (2009)	3
ERBB3	3	PTPN11	20	affinity chromatography technology, two hybrid	Crovello CS (1998), Yao Z (2017)	2
MED21	1	SRC	2	affinity chromatography technology	Huttlin EL (2017)	1
FBXW7	2	TRIM25	5	two hybrid	Arroyo R (2015)	1
NTRK1	1	GAB1	3	affinity chromatography technology	Emdal KB (2015)	1
FSD1	3	CHRAC1	0	affinity chromatography technology	Huttlin EL (2017)	1
PIK3R1	6	GAB1	3	pull down, affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology	Bertagnolo V (1998), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Rocchi S (1998), Ingham RJ (1998), Ingham RJ (1998), Fan YX (2013)	7
TXNIP	2	KDR	4	affinity chromatography technology	Park SY (2013)	1
DUSP13	1	PTPN11	20	affinity chromatography technology	Li X (2016)	1
IRS2	6	PTPN11	20	affinity chromatography technology	Argetsinger LS (1996)	1
FCRL3	2	PTPN11	20	pull down	Xu MJ (2002)	1
ERBB4	5	STAT5A	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Williams CC (2004), Schulze WX (2006), Sundvall M (2012)	3
KIT	4	CRK	0	two hybrid	Yokouchi M (1997)	1
KIT	4	INPP5D	2	pull down	van Dijk TB (2000)	1
TRIM25	5	STAT5B	3	affinity chromatography technology	Choudhury NR (2017)	1
PTPN11	20	JAK2	1	pull down, enzymatic study, enzymatic study, affinity chromatography technology	Yin T (1997), Yin T (1997), Tauchi T (1996), Maegawa H (1996)	4
SOCS1	1	PIK3R1	6	two hybrid	Grossmann A (2015)	1
TRIM25	5	PRPF19	2	affinity chromatography technology	Choudhury NR (2017)	1
INSR	9	FRS2	0	enzymatic study	Delahaye L (2000)	1
NTRK1	1	STAT3	0	affinity chromatography technology	Emdal KB (2015)	1
PTPN11	20	LNX1	7	two hybrid	Grossmann A (2015)	1
IGF1R	5	PIK3R1	6	imaging technique	Chen TC (2014)	1
INSR	9	GRB2	2	affinity chromatography technology	Ishihara H (1997)	1
FYN	1	PLCG2	11	pull down	Pleiman CM (1993)	1
IL4R	1	ERBB2	6	affinity chromatography technology	Huttlin EL (2017)	1
PTK2	2	STAT1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Xie B (2001), Xie B (2001), Xie B (2001), Zhang L (2010), Zhang L (2010), Chen TC (2014)	6
PTK2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Manes S (1999), Takahashi A (2011)	2
TRIM25	5	GTF2E2	2	affinity chromatography technology	Choudhury NR (2017)	1
ELAVL1	0	TLK1	5	affinity chromatography technology	Abdelmohsen K (2009)	1
FCGR2B	3	FCGR2A	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CBL	7	IRS1	7	affinity chromatography technology	Ahmed Z (2000)	1
FGFR2	6	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Seo DW (2003)	2
PDCD1	4	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
LEO1	3	PAF1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, biochemical, affinity chromatography technology	Rozenblatt-Rosen O (2005), Nordick K (2008), Nordick K (2008), Nordick K (2008), Kim J (2010), Mak AB (2010), Mak AB (2010), Takahashi A (2011), Havugimana PC (2012), Rolland T (2014), Wan C (2015), Hein MY (2015)	12
MAPK14	0	EGFR	5	enzymatic study	Raingeaud J (1995)	1
PTPN11	20	BEX1	0	two hybrid	Daakour S (2016)	1
HDAC6	0	DDX58	3	affinity chromatography technology, affinity chromatography technology	Choi SJ (2016), Choi SJ (2016)	2
IRS1	7	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Skolnik EY (1993), Skolnik EY (1993), Skolnik EY (1993), Morrison KB (2002), Giorgetti-Peraldi S (1995), Liu BA (2012), Bisson N (2011)	7
PIK3R1	6	EPHA2	3	pull down, affinity chromatography technology, two hybrid	Pandey A (1994), Pandey A (1994), Pandey A (1994)	3
PTPN11	20	PDGFRA	3	affinity chromatography technology, enzymatic study	Feng H (2012), Vogel W (1996)	2
ELAVL1	0	TXNIP	2	affinity chromatography technology	Abdelmohsen K (2009)	1
PTPN11	20	SIRPA	1	affinity chromatography technology, affinity chromatography technology	Wu CJ (2000), Kapoor GS (2010)	2
DUSP13	1	GRB2	2	affinity chromatography technology	Li X (2016)	1
SRC	2	GAB3	2	pull down	Wolf I (2002)	1
PTPN11	20	CSF3R	2	far western blotting	Ward AC (1998)	1
ERBB2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scaltriti M (2009), Shtiegman K (2007), Haslekas C (2005), Riedemann J (2007), Burke P (2001), Meijer IM (2011), Chen TC (2014), Li J (2013), Li J (2013), Caiazza F (2010), Caiazza F (2010), Sharif A (2009)	12
SRC	2	ERBB2	6	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Ren Z (2002), Li X (2007), Liang K (2010), Liang K (2010), Shen JP (2017)	5
FYN	1	CAV1	0	biochemical	Mastick CC (1997)	1
EGFR	5	PDGFRB	8	affinity chromatography technology	Habib AA (1998)	1
PAF1	6	RTF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Nordick K (2008), Nordick K (2008), Kim J (2010), Kim J (2010), Havugimana PC (2012), Wan C (2015)	6
JAK2	1	ERBB3	3	unspecified method	Jones RB (2006)	1
PTK2	2	SRC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Hecker TP (2002), Angers-Loustau A (1999), Relou IA (2003), Messina S (2003), Lebrun P (1998), Ponnala S (2011), Grossmann A (2015), Chen TC (2014), Lee J (2013), Reiske HR (2000)	11
CBL	7	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kassenbrock CK (2002), Rafiq K (2011), Rellahan BL (2003), Vantler M (2006), Shishido T (2000), Shishido T (2000), Song JJ (2010), Sanjay A (2006), Sanjay A (2006), Tanaka S (1995), Tanaka S (1995), Tanaka S (1995), Szymkiewicz I (2004), Hashimoto S (2006)	14
NOSIP	2	EPOR	3	affinity chromatography technology	Friedman AD (2003)	1
NTRK1	1	STAT5B	3	affinity chromatography technology	Emdal KB (2015)	1
PTPN6	0	PTK2B	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ganju RK (2000), Ganju RK (2000), Kumar S (1999), Kumar S (1999), Kumar S (1999)	5
IGF1R	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Manes S (1999), Seely BL (1995), Seely BL (1995), Yao Z (2017)	4
PTPN11	20	SELE	0	affinity chromatography technology	Hu Y (2001)	1
MAP2K1	8	PTPN11	20	biochemical	Wan C (2015)	1
IL6ST	0	GRB2	2	pull down, affinity chromatography technology	Lee IS (1997), Lee IS (1997)	2
PTPN11	20	NSUN5	1	two hybrid	Daakour S (2016)	1
CD84	0	PTPN11	20	affinity chromatography technology	Morra M (2001)	1
SOS1	5	EGFR	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian X (2000), Qian X (1998), Buday L (1994), Tong J (2009), Kurada BR (2009), Tong J (2008), Foerster S (2013), Tong J (2014), Kapoor GS (2010)	9
CRK	0	GRB2	2	pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Riordan SM (2000), Matsuda M (1996), Okada S (1996), Okada S (1996), Garcia-Guzman M (2000), Brehme M (2009)	6
PTPN11	20	SLC38A1	2	two hybrid	Daakour S (2016)	1
PDGFRA	3	KIT	4	affinity chromatography technology	Zhu MJ (2007)	1
VCAM1	2	DNM2	2	affinity chromatography technology	Humphries JD (2009)	1
LEO1	3	CTR9	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rozenblatt-Rosen O (2005), Nordick K (2008), Nordick K (2008), Kim J (2010), Mak AB (2010), Mak AB (2010), Ouna BA (2012), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Hein MY (2015), Boldt K (2016)	12
SOCS3	0	SIGLEC7	0	affinity chromatography technology	Orr SJ (2007)	1
GOLGA2	2	CDC73	1	two hybrid	Rolland T (2014)	1
TMEM220	0	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
PTPN11	20	RPIA	0	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
ROS1	3	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBL	7	CBLB	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Rorsman C (2016)	2
GHR	1	JAK2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Frank SJ (1995), VanderKuur JA (1994), Hellgren G (1999), Putters J (2011), Sedek M (2014)	5
FCRL3	2	PTPN6	0	affinity chromatography technology, pull down	Xu MJ (2002), Xu MJ (2002)	2
KDR	4	DNM2	2	affinity chromatography technology	Bhattacharya R (2005)	1
FYN	1	CBLB	3	two hybrid	Grossmann A (2015)	1
CBL	7	ERBB2	6	pull down, affinity chromatography technology	Zhou P (2003), Bisaro B (2016)	2
GTF2E2	2	EFHD2	2	affinity chromatography technology	Huttlin EL (2017)	1
STAT5A	4	STAT5B	3	affinity chromatography technology	Huttlin EL (2017)	1
LGALS3	0	PRPF19	2	affinity chromatography technology	Carvalho RS (2014)	1
PTPN6	0	INSR	9	affinity chromatography technology	Uchida T (1994)	1
STAT1	1	STAT5A	4	imaging technique	Chen TC (2014)	1
EGFR	5	SOCS3	0	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Xia L (2002), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
IRS2	6	SOCS3	0	affinity chromatography technology, affinity chromatography technology	Calegari VC (2005), Calegari VC (2005)	2
PTK2	2	ERBB2	6	imaging technique, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Ritch PA (2003), Ritch PA (2003)	3
CDC73	1	WDR61	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Mak AB (2010), Wu J (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015)	5
NTRK1	1	FSD1	3	affinity chromatography technology	Emdal KB (2015)	1
PTPN11	20	LINC01558	0	two hybrid	Daakour S (2016)	1
NTRK1	1	SRC	2	affinity chromatography technology	Emdal KB (2015)	1
ERBB2	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method	Schulze WX (2006), Bourguignon LY (2001), Olayioye MA (1998), Li X (2007), Li X (2007), Crovello CS (1998), Jones RB (2006)	7
SRC	2	5175	0	affinity chromatography technology, affinity chromatography technology	Cicmil M (2000), Relou IA (2003)	2
PTPN11	20	PRPF19	2	affinity chromatography technology, affinity chromatography technology	Zheng J (2016), Zheng J (2016)	2
EGFR	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology, enzymatic study	Schulze WX (2006), Tomic S (1995), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Kapoor GS (2010), Vogel W (1996)	7
FYN	1	CBL	7	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Taher TE (2002), Deckert M (1998), Deckert M (1998), Deckert M (1998), Ghosh AK (2004), Rellahan BL (2003), Boussiotis VA (1997), Andoniou CE (2000), Shishido T (2000), Okabe S (2006), Kaabeche K (2004), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tanaka S (1995), Reedquist KA (1996), Grossmann AH (2004), Panchamoorthy G (1996), Fukazawa T (1995), Fukazawa T (1995), Fukazawa T (1995), Nishio H (2002), Anderson SM (1997), Fukazawa T (1996), Grossmann A (2015)	27
ERBB4	5	CRK	0	affinity chromatography technology	Schulze WX (2006)	1
FGFR2	6	BEX2	0	two hybrid	Arroyo R (2015)	1
CAV1	0	PDGFRB	8	affinity chromatography technology, biochemical, pull down	Yamamoto M (1999), Yamamoto M (1999), Yamamoto M (1999)	3
MAPK14	0	OXCT1	1	biochemical	Kristensen AR (2012)	1
NTRK1	1	PIK3R1	6	affinity chromatography technology	Emdal KB (2015)	1
PTPN6	0	LAIR1	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Sathish JG (2001), Sathish JG (2001), Fournier N (2000), Meyaard L (1997), Mousseau DD (2000), Xu M (2000), Xu M (2000), Xu M (2000), Yamaji T (2005)	9
ELAVL1	0	HDAC6	0	affinity chromatography technology, affinity chromatography technology	Scott GK (2008), Scott GK (2008)	2
GAB2	3	GAB1	3	two hybrid	van den Akker E (2004)	1
ROS1	3	GRB2	2	biochemical	Wan C (2015)	1
CBLB	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Ettenberg SA (1999), Lavagna-Sevenier C (1998), Lavagna-Sevenier C (1998), Elly C (1999), Bandyopadhyay S (2010), Vinayagam A (2011), Bisson N (2011), Blagoev B (2003), Rolland T (2014), Huttlin EL (2017)	10
BCAR1	6	FYN	1	two hybrid, affinity chromatography technology, pull down	Donaldson JC (2000), Manie SN (1997), Manie SN (1997)	3
IGF1R	5	TRIM25	5	two hybrid, affinity chromatography technology	Arroyo R (2015), Choudhury NR (2017)	2
JAK1	6	SOCS1	1	affinity chromatography technology	Park ES (2000)	1
RTF1	3	CDC73	1	affinity chromatography technology	Kim J (2010)	1
PTK2	2	SOCS3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Le Y (2007), Le Y (2007), Niwa Y (2005), Rolland T (2014)	4
PTPN6	0	PTK2	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
SRC	2	KIT	4	unspecified method	Wollberg P (2003)	1
GOLGA2	2	LGALS3	0	two hybrid	Rolland T (2014)	1
PTPN11	20	ORMDL3	0	two hybrid	Daakour S (2016)	1
TRIM25	5	SLC38A1	2	affinity chromatography technology	Choudhury NR (2017)	1
CBLB	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavagna-Sevenier C (1998), Elly C (1999), Elly C (1999), Alcazar I (2009), Fang D (2001)	5
PPIF	0	PTPN11	20	biochemical	Havugimana PC (2012)	1
FGFR2	6	FRS2	0	affinity chromatography technology, affinity chromatography technology	Severe N (2011), Ceridono M (2005)	2
PTPN11	20	CTDSP1	0	two hybrid	Daakour S (2016)	1
TRIM25	5	MAP2K1	8	affinity chromatography technology	Choudhury NR (2017)	1
LAIR1	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Fournier N (2000), Meyaard L (1997)	2
SOCS1	1	MAP3K5	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	He Y (2006), He Y (2006), He Y (2006), Kolliputi N (2009), Kolliputi N (2009)	5
LRRK1	12	PTPN11	20	affinity chromatography technology	Titz B (2010)	1
PTPN6	0	STAT5B	3	affinity chromatography technology	Ram PA (1997)	1
FBXW7	2	MED21	1	affinity chromatography technology, affinity chromatography technology	Davis MA (2013), Kourtis N (2015)	2
5175	0	PTPN6	0	pull down, far western blotting, affinity chromatography technology, pull down	Pumphrey NJ (1999), Pumphrey NJ (1999), Hua CT (1998), Hua CT (1998)	4
PTPN11	20	PTK2B	6	affinity chromatography technology, affinity chromatography technology, far western blotting, enzymatic study	Chauhan D (2000), Chauhan D (2000), Chauhan D (2000), Chauhan D (2000)	4
GRASP	1	SRC	2	affinity chromatography technology, enzymatic study	Hirose M (2004), Hirose M (2004)	2
INSR	9	IRS1	7	two hybrid, two hybrid, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Aguirre V (2002), Sawka-Verhelle D (1996), Strack V (2002), Wolf G (1995), Kwon H (2015), Kwon H (2015)	6
TCEAL1	3	TRIM25	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PDGFRB	8	STAT5A	4	imaging technique	Chen TC (2014)	1
GAB2	3	CRKL	1	affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology	Crouin C (2001), Crouin C (2001), Crouin C (2001), Schaeper U (2000)	4
EGFR	5	CRK	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Hashimoto Y (1998), Hashimoto Y (1998), Katayama H (1999), Ota S (1998), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	9
EGFR	5	ERBB4	5	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology	Meijer IM (2013), Kiuchi T (2014), Kiuchi T (2014)	3
IL4R	1	PTPN6	0	pull down, affinity chromatography technology	Kashiwada M (2001), Warren KJ (2016)	2
PTPN11	20	TRMT2B	1	two hybrid	Daakour S (2016)	1
SRC	2	PTPN11	20	enzymatic study	Vogel W (1996)	1
LRRK1	12	GRB2	2	affinity chromatography technology, affinity chromatography technology	Titz B (2010), Brehme M (2009)	2
CEACAM1	1	PTPN11	20	affinity chromatography technology, pull down	Huber M (1999), Huber M (1999)	2
PTK7	8	PTPN6	0	two hybrid	Yao Z (2017)	1
FYN	1	SLAMF1	2	pull down	Chan B (2003)	1
NTRK1	1	EGFR	5	affinity chromatography technology	Emdal KB (2015)	1
JAK1	6	IRS1	7	enzymatic study, affinity chromatography technology	Gual P (1998), Johnston JA (1995)	2
NTRK1	1	PTK7	8	affinity chromatography technology	Emdal KB (2015)	1
TRIM25	5	DDX58	3	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Gack MU (2007), Gack MU (2007), Gack MU (2007), Gack MU (2010), Nistal-Villan E (2010), Nistal-Villan E (2010), Inn KS (2011), Inn KS (2011), Maharaj NP (2011), Oshiumi H (2013), Weng L (2014), Xia ZP (2009), Feng M (2012), Gao D (2009), Gao D (2009), Jiang J (2016), Hu Y (2017), Hu Y (2017)	18
SIGLEC7	0	PTPN6	0	affinity chromatography technology	Yamaji T (2005)	1
PDGFRA	3	STAT3	0	imaging technique	Chen TC (2014)	1
NTRK1	1	INSR	9	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	STAT5A	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, enzymatic study, imaging technique	Schulze WX (2006), Schulze WX (2006), Olayioye MA (1999), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Fan QW (2013), Latha K (2013)	8
LGALS3	0	MPZL1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAPK14	0	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP3K5	1	SOCS3	0	affinity chromatography technology	He Y (2006)	1
SYNCRIP	6	PTPN11	20	two hybrid	Harris CE (1999)	1
FGFR1	2	JAK2	1	affinity chromatography technology	Dudka AA (2010)	1
KDR	4	CAV1	0	biochemical	Tiwari A (2013)	1
SIGLEC11	0	PTPN11	20	affinity chromatography technology	Angata T (2002)	1
CBLB	3	PIK3R2	3	affinity chromatography technology	Alcazar I (2009)	1
EPHA2	3	GRB2	2	affinity chromatography technology, pull down	Pratt RL (2002), Pratt RL (2002)	2
PIK3R1	6	EPOR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, protein complementation assay, affinity chromatography technology	Shigematsu H (1997), Shigematsu H (1997), Damen JE (1995), Damen JE (1995), Montoye T (2005), Bulut GB (2013)	6
IGF1R	5	PTK2	2	affinity chromatography technology	Manes S (1999)	1
ROR2	0	PTPN11	20	two hybrid	Yao Z (2017)	1
GRB2	2	SIRPA	1	affinity chromatography technology	Bisson N (2011)	1
GRB2	2	GHR	1	pull down	Moutoussamy S (1998)	1
GRB2	2	PTK2	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, two hybrid	Sieg DJ (2000), Angers-Loustau A (1999), Hildebrand JD (1996), Messina S (2003), Arold ST (2002), Vinayagam A (2011)	6
CRK	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	Gelkop S (2001), Gelkop S (2001), Garcia-Guzman M (2000), Brehme M (2009), Grossmann A (2015), Chen TC (2014)	6
EGFR	5	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Yuan ZL (2004), Olayioye MA (1999), Lo HW (2005), Lo HW (2005), Crovello CS (1998), Jaganathan S (2011), Jaganathan S (2011), Andl CD (2004), Lo HW (2010), Foerster S (2013), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), de la Iglesia N (2008), Fan QW (2013), Fan QW (2013)	18
PTK2	2	EGFR	5	affinity chromatography technology, two hybrid, protein complementation assay	Sieg DJ (2000), Kotlyar M (2015), Petschnigg J (2014)	3
JAK2	1	STAT3	0	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Ram PA (1997), Manea A (2010), Andl CD (2004), Kamakura S (2004), He K (2013), Kucia-Tran JA (2016), M L (2016)	7
EPHA1	5	PTPN11	20	two hybrid	Yao Z (2017)	1
EGFR	5	PLCG2	11	unspecified method, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014)	5
ELAVL1	0	RFWD2	0	affinity chromatography technology	Abdelmohsen K (2009)	1
TEK	2	PTPN11	20	two hybrid	Yao Z (2017)	1
GAB2	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down	Lynch DK (2002), Crouin C (2001), Crouin C (2001), Schaeper U (2000), Ren SY (2005), Momose H (2003)	6
IRS1	7	IRS2	6	biochemical	Sun H (2003)	1
PTPN11	20	GHR	1	pull down, pull down	Stofega MR (2000), Moutoussamy S (1998)	2
CAV1	0	SRC	2	pull down	Li S (1996)	1
GSK3B	1	PTK2	2	affinity chromatography technology	Huang D (2002)	1
SIGLEC5	2	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
CD274	2	PDCD1	4	pull down, pull down	Ramani SR (2012), Ramani SR (2012)	2
CDH5	2	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lewalle JM (1997), Shasby DM (2002), Margariti A (2010), Cho T (2013), Huttlin EL (2017), Chang CC (2012), Chang CC (2012)	7
INSR	9	IRS2	6	two hybrid	Sawka-Verhelle D (1996)	1
IQCB1	3	OXCT1	1	affinity chromatography technology	Sang L (2011)	1
DDX58	3	CBL	7	affinity chromatography technology	Song Y (2017)	1
LUM	0	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
HDAC6	0	FASN	15	affinity chromatography technology	Watson GW (2016)	1
STAT1	1	PDGFRA	3	imaging technique	Chen TC (2014)	1
8339	0	PTPN11	20	bioid	Lambert JP (2015)	1
CRK	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Larsson H (1999)	2
NTRK1	1	PTPN11	20	affinity chromatography technology	Emdal KB (2015)	1
LGALS9	0	MPZL1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
STAT3	0	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology	Gunaje JJ (2001), Spiekermann K (2001), Xia L (2002), Chen TC (2014), Li X (2015), Ghosh MK (2005), Huttlin EL (2017)	7
STAMBP	2	PTPN11	20	biochemical	Wan C (2015)	1
SIGLEC9	1	PTPN11	20	affinity chromatography technology	Yamaji T (2005)	1
CSF3R	2	JAK1	6	affinity chromatography technology	Nicholson SE (1994)	1
STAT3	0	FGFR2	6	affinity chromatography technology, affinity chromatography technology	Dudka AA (2010), Dudka AA (2010)	2
JAK2	1	PTPN6	0	affinity chromatography technology, affinity chromatography technology	Jiao H (1996), Wu DW (2000)	2
KIT	4	SOCS1	1	two hybrid, affinity chromatography technology	De Sepulveda P (1999), De Sepulveda P (1999)	2
NXT2	0	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
PTK2B	6	ERBB2	6	affinity chromatography technology, imaging technique	Zrihan-Licht S (2000), Chen TC (2014)	2
ERBB3	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Li J (2013)	3
BCAR1	6	PTK2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Salgia R (1996), Hsia DA (2003), Hildebrand JD (1996), Chellaiah MA (2001), Okabe S (2002), Wang JF (2000), Wu Y (2005), Ponnala S (2011), Cho SY (2002)	9
STAT3	0	PIK3R2	3	two hybrid	Grossmann A (2015)	1
IL6ST	0	PIK3R1	6	affinity chromatography technology	Chung TD (2000)	1
PTPN11	20	FASN	15	affinity chromatography technology, affinity chromatography technology	Yu J (2012), Yu J (2012)	2
BCAR1	6	ERBB2	6	affinity chromatography technology	Bisaro B (2016)	1
CBL	7	IGF1R	5	enzymatic study, affinity chromatography technology	Sehat B (2008), Sehat B (2008)	2
GAREM2	1	PTPN11	20	affinity chromatography technology	Taniguchi T (2013)	1
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
TCEAL1	3	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KDR	4	GRB2	2	affinity chromatography technology	DAngelo G (1999)	1
SOCS3	0	CXCR4	0	affinity chromatography technology	Soriano SF (2002)	1
ERBB2	6	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	EPHA2	3	affinity chromatography technology	Tong J (2014)	1
CBL	7	PDGFRA	3	affinity chromatography technology, pull down	Bonita DP (1997), Bonita DP (1997)	2
JAK2	1	SOCS1	1	two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Yasukawa H (1999), Dif F (2001), Endo TA (1997), Endo TA (1997), Endo TA (1997), Yasukawa H (1999), Yasukawa H (1999), Pezet A (1999), Ungureanu D (2002), Masuhara M (1997), Ali S (2003), Monni R (2001), Monni R (2001), Piessevaux J (2008), Yu L (2009), Maruoka M (2017)	16
NXT2	0	LNX1	7	two hybrid	Rolland T (2014)	1
PRLR	0	PTPN11	20	affinity chromatography technology	Ali S (2000)	1
CXCR4	0	CAV1	0	biochemical	Malik R (2012)	1
CBL	7	KDR	4	pull down, affinity chromatography technology	Singh AJ (2007), Wang Y (2009)	2
LY9	1	PTPN11	20	affinity chromatography technology	Morra M (2001)	1
FGFR1	2	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dudka AA (2010), Dudka AA (2010), Dudka AA (2010)	3
ELAVL1	0	IRS2	6	affinity chromatography technology	Abdelmohsen K (2009)	1
PTPN11	20	STAT5B	3	pull down, enzymatic study	Yu CL (2000), Yu CL (2000)	2
TRIM25	5	GRB2	2	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	BCAR1	6	affinity chromatography technology	Choudhury NR (2017)	1
EGFR	5	STAT5B	3	affinity chromatography technology, affinity chromatography technology, imaging technique	Runge DM (1999), Latha K (2013), Latha K (2013)	3
IGF1R	5	CRKL	1	imaging technique	Chen TC (2014)	1
GHR	1	JAK1	6	affinity chromatography technology	Hellgren G (1999)	1
RTF1	3	STAT1	1	biochemical	Kristensen AR (2012)	1
HDAC6	0	GSK3B	1	affinity chromatography technology	Beurel E (2011)	1
INSR	9	SOCS1	1	affinity chromatography technology	Mooney RA (2001)	1
FGFR1	2	CRKL	1	affinity chromatography technology	Seo JH (2009)	1
DNM2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Feng H (2012), Feng H (2012)	2
FYN	1	5175	0	affinity chromatography technology	Cicmil M (2000)	1
STAT5A	4	GHR	1	imaging technique	Chen TC (2014)	1
EGFR	5	LRRK1	12	affinity chromatography technology	Yao Z (2017)	1
GRB2	2	INPP5D	2	unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kavanaugh WM (1996), Kavanaugh WM (1996), de Castro RO (2012), Ho JM (2002)	4
SOS1	5	PTPN6	0	affinity chromatography technology	Kon-Kozlowski M (1996)	1
ELAVL1	0	NXT2	0	affinity chromatography technology	Abdelmohsen K (2009)	1
GRB2	2	GAB3	2	pull down, pull down	Wolf I (2002), Wolf I (2002)	2
EPOR	3	CBL	7	affinity chromatography technology	Wakioka T (1999)	1
INSR	9	SYNCRIP	6	enzymatic study	Hresko RC (2002)	1
OVCA2	1	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KIT	4	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zeng S (2005), Brizzi MF (1996), Dong Y (2015)	3
CRKL	1	SOCS1	1	two hybrid	Grossmann A (2015)	1
SRC	2	ERBB3	3	unspecified method	Jones RB (2006)	1
CAV1	0	NTRK1	1	affinity chromatography technology	Bilderback TR (1999)	1
CBL	7	SOS1	5	affinity chromatography technology	Wang Y (1999)	1
ERBB3	3	PTPN6	0	two hybrid	Yao Z (2017)	1
TRIM25	5	260294	0	affinity chromatography technology	Choudhury NR (2017)	1
PLCG2	11	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Boudot C (2002)	2
CTR9	10	WDR61	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Kim J (2010), Mak AB (2010), Wu J (2012), Wan C (2015), Hein MY (2015)	5
CBL	7	PTK2	2	imaging technique, affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Schmidt MH (2003), Sekine Y (2007)	3
EGFR	5	NSUN5	1	affinity chromatography technology	Tong J (2014)	1
NTRK1	1	HDAC6	0	affinity chromatography technology	Emdal KB (2015)	1
FYN	1	FGFR2	6	affinity chromatography technology	Kaabeche K (2004)	1
PDGFRA	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, imaging technique	Zhu MJ (2007), Zhu MJ (2007), Chen TC (2014)	3
PTK2	2	PIK3R1	6	affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guinebault C (1995), Guinebault C (1995), Lee DY (2010), Reddy MA (2000), Reiske HR (2000)	5
EFHD2	2	PTPN11	20	biochemical	Kristensen AR (2012)	1
ELAVL1	0	CHRAC1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
FGFR1	2	CTNNB1	30	imaging technique, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Boscher C (2008), Boscher C (2008)	3
ERBB4	5	CBL	7	affinity chromatography technology	Kiuchi T (2014)	1
FGFR1	2	PIK3R2	3	two hybrid	Hu Y (2004)	1
PIK3R1	6	SOS1	5	imaging technique	Chen TC (2014)	1
KDR	4	PTPN11	20	two hybrid, affinity chromatography technology, far western blotting	Yao Z (2017), Mitola S (2006), Mitola S (2006)	3
PTPN11	20	SERPINF1	1	two hybrid	Daakour S (2016)	1
TRIM25	5	FRS2	0	affinity chromatography technology	Choudhury NR (2017)	1
LGALS9	0	LGALS3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGFR	5	PDGFRA	3	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
PTPN11	20	PTPN6	0	affinity chromatography technology	Li X (2016)	1
SOCS3	0	IGF1R	5	pull down, two hybrid, affinity chromatography technology	Dey BR (2000), Dey BR (2000), Dey BR (2000)	3
FYN	1	GAB3	2	pull down	Wolf I (2002)	1
SIGLEC7	0	PTPN11	20	affinity chromatography technology	Yamaji T (2005)	1
JAK1	6	STAT5B	3	two hybrid, affinity chromatography technology, affinity chromatography technology	Fujitani Y (1997), Fujitani Y (1997), Fujitani Y (1997)	3
EGFR	5	CDH5	2	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
CSF2RB	6	JAK1	6	affinity chromatography technology	Lei JT (2011)	1
SRC	2	PTPN6	0	enzymatic study	Frank C (2004)	1
ELAVL1	0	GRB2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
5175	0	CTNNB1	30	affinity chromatography technology, imaging technique	Ilan N (2000), Chen TC (2014)	2
PTPN11	20	GTF2A2	0	two hybrid	Daakour S (2016)	1
CRK	0	PDGFRB	8	affinity chromatography technology, pull down	Matsumoto T (2000), Matsumoto T (2000)	2
GAB1	3	FRS2	0	affinity chromatography technology	Zhou L (2015)	1
SELE	0	PTK2	2	pull down	Yoshida M (1996)	1
PIK3R2	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017)	3
BCAR1	6	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology	Zhou B (2004), Di Stefano P (2004), Hsia DA (2003), Hsia DA (2003), Gu J (2001), Garton AJ (1999), Angers-Loustau A (1999), Qiu W (1998), Blaukat A (1999), Wang JF (2000), Holcomb M (2006), Wu Y (2005), Cho SY (2000), Modzelewska K (2006), Modzelewska K (2006), Brehme M (2009), Cho SY (2002), Cho SY (2002), Mielenz D (2001), Peterson ME (2008), Liu BA (2012), Larsson H (1999)	22
PTK7	8	PTPN11	20	two hybrid	Yao Z (2017)	1
MPIG6B	0	PTPN11	20	affinity chromatography technology	de Vet EC (2001)	1
PDGFRB	8	CBLB	3	affinity chromatography technology	Rorsman C (2016)	1
LGALS9	0	LUM	0	affinity chromatography technology	Huttlin EL (2015)	1
FGFR2	6	CTDSP1	0	two hybrid	Yao Z (2017)	1
JAK2	1	STAT1	1	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Cheng MB (2010), Cheng MB (2010), Manea A (2010), Andl CD (2004), Chang YJ (2004)	5
PTPN11	20	SRSF10	0	two hybrid	Daakour S (2016)	1
EPHA2	3	PTPN11	20	affinity chromatography technology, two hybrid	Miao H (2000), Yao Z (2017)	2
ERBB3	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hellyer NJ (2001), Lin J (1999), Crovello CS (1998), Graus-Porta D (1997), Jones RB (2006), Li J (2013), Servidei T (2008), Servidei T (2008), Ritch PS (2005), Tang X (2002)	10
CRKL	1	INPP5D	2	pull down, affinity chromatography technology	Arai A (2001), Arai A (2001)	2
GSK3B	1	BEX1	0	two hybrid	Vinayagam A (2011)	1
ERBB2	6	PLCG2	11	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
JAK2	1	SIRPA	1	affinity chromatography technology	Stofega MR (2000)	1
IRS1	7	SOCS1	1	affinity chromatography technology, affinity chromatography technology	Rui L (2002), Li JY (2007)	2
ERBB2	6	STAT1	1	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
GTF2E2	2	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
IGF1R	5	ERBB2	6	affinity chromatography technology	Riedemann J (2007)	1
GHR	1	STAT3	0	pull down	Yi W (1996)	1
SIT1	1	PTPN11	20	affinity chromatography technology	Marie-Cardine A (1999)	1
PTPN11	20	LEO1	3	affinity chromatography technology	Takahashi A (2011)	1
NTRK1	1	GOLGA2	2	affinity chromatography technology	Emdal KB (2015)	1
INSR	9	SOCS3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Senn JJ (2003), Calegari VC (2005), Calegari VC (2005)	3
PTK2B	6	JAK1	6	affinity chromatography technology	Benbernou N (2000)	1
NTRK1	1	PDGFRA	3	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	CBLB	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Schulze WX (2006), Ettenberg SA (1999), Davies GC (2006), Davies GC (2006), Tong J (2009), Ettenberg SA (2001), Tong J (2008), Levkowitz G (1999), Tong J (2014)	9
FYN	1	PIK3R1	6	pull down	Kapeller R (1994)	1
FYN	1	GRASP	1	enzymatic study	Hirose M (2004)	1
EGFR	5	CAV1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, pull down, biochemical	Couet J (1997), Couet J (1997), Khan EM (2006), Feldman R (2009), Hua H (2003), Wu SL (2006), Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Park WY (2000), Abulrob A (2004), Abulrob A (2004)	12
CRK	0	GAB2	3	affinity chromatography technology	Brehme M (2009)	1
ERBB2	6	IRS1	7	unspecified method	Jones RB (2006)	1
PTPN11	20	DMRTC1	0	two hybrid	Daakour S (2016)	1
PTPN11	20	GOLGA2	2	two hybrid	Daakour S (2016)	1
PIK3R1	6	PLCG2	11	imaging technique	Chen TC (2014)	1
GHR	1	SOCS1	1	affinity chromatography technology, pull down	Ram PA (1999), Ram PA (1999)	2
FGFR2	6	BEX1	0	two hybrid	Arroyo R (2015)	1
CTNNB1	30	CBL	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Chitalia V (2013), Chitalia V (2013), Chitalia V (2013), Shivanna S (2015)	4
GSK3B	1	PTPN11	20	biochemical	Havugimana PC (2012)	1
KIT	4	PTPN6	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Kozlowski M (1998), Kozlowski M (1998), Kozlowski M (1998), Yi T (1993), Yi T (1993)	5
GRB2	2	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Million RP (2004), Lynch DK (2002), Zhao C (1999), Zhao C (1999), Bandyopadhyay S (2010), Brehme M (2009), Bisson N (2011), Rolland T (2014), Huttlin EL (2017), Yu WM (2006), Yu WM (2006)	11
SOS1	5	FYN	1	pull down	Park C (1998)	1
PTPN11	20	TLK1	5	two hybrid	Daakour S (2016)	1
GOLGA2	2	PIK3R2	3	two hybrid	Rolland T (2014)	1
CXCR4	0	PTPN11	20	affinity chromatography technology	Chernock RD (2001)	1
VCAM1	2	FASN	15	affinity chromatography technology	Humphries JD (2009)	1
DNM2	2	PIK3R1	6	affinity chromatography technology	Feng H (2012)	1
SOCS3	0	PTK2B	6	two hybrid, affinity chromatography technology	Masuhara M (1997), Zhang S (2008)	2
CTNNB1	30	ELAVL1	0	pull down	Kim I (2012)	1
VCAM1	2	SYNCRIP	6	affinity chromatography technology	Humphries JD (2009)	1
CD33	2	PTPN6	0	affinity chromatography technology, pull down	Taylor VC (1999), Taylor VC (1999)	2
BLZF1	0	BEX2	0	two hybrid	Rolland T (2014)	1
PTPN11	20	PLEKHA4	4	two hybrid	Daakour S (2016)	1
FGFR1	2	PLCG2	11	affinity chromatography technology	Vecchione A (2007)	1
STAMBP	2	GRB2	2	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bandyopadhyay S (2010), Sierra MI (2010), Sierra MI (2010), Sierra MI (2010), Kikuchi K (2003), Tsang HT (2006), Bisson N (2011), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	11
ELAVL1	0	EPHA2	3	affinity chromatography technology	Abdelmohsen K (2009)	1
CRKL	1	STAT5A	4	affinity chromatography technology, pull down, affinity chromatography technology	Ota J (1998), Ota J (1998), Oda A (1998)	3
ERBB4	5	ERBB2	6	affinity chromatography technology	Huang YZ (2000)	1
JAK1	6	STAT5A	4	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Fujitani Y (1997), Fujitani Y (1997), Fujitani Y (1997), Fujitani Y (1997)	4
NOSIP	2	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
IRS1	7	PIK3R2	3	affinity chromatography technology	Kuchay S (2013)	1
PTPN6	0	EPOR	3	affinity chromatography technology, pull down	Klingmueller U (1995), Klingmueller U (1995)	2
ELAVL1	0	GSK3B	1	affinity chromatography technology	Abdelmohsen K (2009)	1
NTRK1	1	RTF1	3	affinity chromatography technology	Emdal KB (2015)	1
FGFR2	6	STAT5A	4	affinity chromatography technology, affinity chromatography technology	Cerliani JP (2011), Cerliani JP (2011)	2
FCGR2A	0	PIK3R1	6	affinity chromatography technology, pull down	Chacko GW (1996), Ibarrola I (1997)	2
EPOR	3	INPP5D	2	protein complementation assay	Montoye T (2005)	1
PTPN11	20	RFWD2	0	affinity chromatography technology	Yu J (2012)	1
AATK	6	PTPN11	20	two hybrid	Yao Z (2017)	1
FYN	1	SOCS1	1	pull down	De Sepulveda P (1999)	1
GAB2	3	PTPN6	0	affinity chromatography technology	Yu WM (2002)	1
ERBB3	3	CRKL	1	unspecified method	Jones RB (2006)	1
ERBB2	6	PIK3R2	3	pull down, unspecified method	Gout I (1992), Jones RB (2006)	2
JAK1	6	STAT1	1	affinity chromatography technology, affinity chromatography technology	Andl CD (2004), Chang YJ (2004)	2
FGB	2	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
ERBB4	5	PTPN11	20	affinity chromatography technology, enzymatic study, two hybrid	Schulze WX (2006), Yao Z (2017), Yao Z (2017)	3
BCAR1	6	PIK3R1	6	affinity chromatography technology, pull down	Li E (2000), Li E (2000)	2
EPOR	3	PTPN11	20	affinity chromatography technology, pull down	Tauchi T (1996), Tauchi T (1995)	2
ELAVL1	0	PTPN11	20	affinity chromatography technology	Abdelmohsen K (2009)	1
FRS2	0	CBL	7	affinity chromatography technology, pull down, affinity chromatography technology	Wong A (2002), Wong A (2002), Belleudi F (2007)	3
CDC73	1	CTR9	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rozenblatt-Rosen O (2005), Rozenblatt-Rosen O (2005), Nordick K (2008), Nordick K (2008), Rozenblatt-Rosen O (2009), Kim J (2010), Mak AB (2010), Mak AB (2010), Ouna BA (2012), Takahashi A (2011), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	17
SOCS3	0	EPOR	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Sasaki A (2000), Sasaki A (2000), Sasaki A (2000), Hoertner M (2002)	4
KIT	4	JAK2	1	affinity chromatography technology	Brizzi MF (1994)	1
VCAM1	2	PTPN11	20	affinity chromatography technology	Humphries JD (2009)	1
PTPN11	20	23772	0	affinity chromatography technology	Craddock BL (1997)	1
CXCR4	0	JAK2	1	affinity chromatography technology	Vila-Coro AJ (1999)	1
GRB2	2	PIK3R2	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009), Brehme M (2009), Bisson N (2011)	4
JAK2	1	IRS1	7	enzymatic study, affinity chromatography technology	Gual P (1998), Kawazoe Y (2001)	2
FGFR1	2	PIK3R1	6	imaging technique, two hybrid, pull down	Chen TC (2014), Hu Y (2004), Shi E (1993)	3
INSR	9	STAT5A	4	affinity chromatography technology	Le MN (2002)	1
LRRK1	12	SOS1	5	affinity chromatography technology	Titz B (2010)	1
GAB2	3	FRS2	0	affinity chromatography technology	Zhou L (2015)	1
PTK2	2	CRK	0	affinity chromatography technology, pull down, two hybrid	Hsia DA (2003), Angers-Loustau A (1999), Grossmann A (2015)	3
INPP5D	2	CBL	7	affinity chromatography technology	Bao M (2012)	1
PTPN11	20	260294	0	two hybrid	Daakour S (2016)	1
PTPN11	20	BEX2	0	two hybrid	Daakour S (2016)	1
DNM2	2	SRC	2	pull down	Solomaha E (2005)	1
NTRK1	1	SOS1	5	affinity chromatography technology	Emdal KB (2015)	1
PTPN6	0	JAK1	6	enzymatic study	Yetter A (1995)	1
EGFR	5	CTNNB1	30	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hazan RB (1998), Schroeder JA (2002), Takahashi K (1997), Li J (2013)	4
SLAMF6	2	PTPN6	0	affinity chromatography technology	Bottino C (2001)	1
PTPN6	0	ERBB4	5	enzymatic study, two hybrid	Yao Z (2017), Yao Z (2017)	2
PTPN11	20	CDC73	1	affinity chromatography technology, affinity chromatography technology	Takahashi A (2011), Takahashi A (2011)	2
FLT1	4	CBL	7	affinity chromatography technology	Raikwar NS (2014)	1
FYN	1	JAK2	1	affinity chromatography technology, pull down	Sayeski PP (1999), Sayeski PP (1999)	2
EPOR	3	STAT5A	4	affinity chromatography technology, pull down, protein complementation assay, pull down	Chin H (1996), Chin H (1996), Montoye T (2005), Wakioka T (1999)	4
TMEM220	0	SRC	2	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	PRPF19	2	affinity chromatography technology	Emdal KB (2015)	1
DNM2	2	GRB2	2	pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Solomaha E (2005), Brehme M (2009), Bisson N (2011), Elhamdani A (2006), Wang J (2011), Huttlin EL (2017)	6
TCEAL1	3	STAT3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IL4R	1	INPP5D	2	pull down	Kashiwada M (2001)	1
EGFR	5	GAB1	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, enzymatic study, affinity chromatography technology	Kameda H (2001), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Lehr S (1999), Mueller KL (2012)	6
PDGFRA	3	GRB2	2	affinity chromatography technology, affinity chromatography technology	Bazenet CE (1996), Severe N (2011)	2
ERBB2	6	JAK1	6	unspecified method	Jones RB (2006)	1
FRS2	0	PTPN11	20	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, unspecified method, affinity chromatography technology	Delahaye L (2000), Delahaye L (2000), Kurokawa K (2001), Hadari YR (1998), Hadari YR (1998), Liu BA (2012), Zhou L (2015)	7
ROS1	3	PTPN6	0	two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology	Keilhack H (2001), Keilhack H (2001), Keilhack H (2001), Keilhack H (2001)	4
INPP5D	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu L (1997), Chernock RD (2001), Chernock RD (2001)	3
JAK1	6	IGF1R	5	pull down	Gual P (1998)	1
PAF1	6	CTR9	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Nordick K (2008), Nordick K (2008), Nordick K (2008), Kim J (2010), Kim J (2010), Mak AB (2010), Mak AB (2010), Takahashi A (2011), Havugimana PC (2012), Wan C (2015), Hein MY (2015)	11
HDAC6	0	IQCB1	3	affinity chromatography technology	Joshi P (2013)	1
CTNNB1	30	PIK3R1	6	pull down, imaging technique	Espada J (1999), Chen TC (2014)	2
BCAR1	6	CBL	7	affinity chromatography technology	Sawasdikosol S (1996)	1
GRB2	2	NTRK1	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Song C (2002), MacDonald JI (2000), Emdal KB (2015), Emdal KB (2015)	4
EGFR	5	IRS2	6	affinity chromatography technology	Tong J (2008)	1
IGF1R	5	STAT3	0	imaging technique	Chen TC (2014)	1
CRK	0	STAT5A	4	imaging technique	Chen TC (2014)	1
BCAR1	6	CRKL	1	far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method	Salgia R (1996), Salgia R (1996), Astier A (1997), Peterson ME (2008), Liu BA (2012)	5
TRIM25	5	IL6ST	0	affinity chromatography technology	Choudhury NR (2017)	1
PDGFRB	8	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Farooqui T (2000), Chamberlain MD (2004), Ren SY (2005), Huttlin EL (2017)	4
CBL	7	CRKL	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Alsayed Y (2000), Alsayed Y (2000), Kyono WT (1998), Lin H (2001), Park RK (1998), Taher TE (2002), Sattler M (1997), Erdreich-Epstein A (1999), Erdreich-Epstein A (1999), Sattler M (1997), Sattler M (1997), Gesbert F (1998), Chin H (1997), Feshchenko EA (2004), Izadi KD (1998), de Jong R (1995), de Jong R (1995), Boussiotis VA (1997), Boussiotis VA (1997), Barber DL (1997), Uemura N (1999), Okabe S (2006), Alsayed Y (2000), Alsayed Y (2000), Brenner B (2001), van Leeuwen JE (1999), Ribon V (1996), Bhat A (1997), Bhat A (1997), Huang JY (2000), Chernock RD (2001), Chernock RD (2001), Grossmann AH (2004), Sakamoto H (2004), Nishihara T (2003), Peterson ME (2008), Fukazawa T (1996), Martelli MP (2001), Joshi S (2014), Grossmann A (2015)	40
FSD1	3	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CRK	0	CBLB	3	affinity chromatography technology, two hybrid, two hybrid	Brehme M (2009), Grossmann A (2015), Grossmann A (2015)	3
CRKL	1	EPOR	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Chin H (1997), Arai A (2001), Arai A (2001), Barber DL (1997)	4
PRLR	0	JAK2	1	affinity chromatography technology, affinity chromatography technology	Pezet A (1997), Ma L (2010)	2
NTRK1	1	LEO1	3	affinity chromatography technology	Emdal KB (2015)	1
GRB2	2	LNX1	7	two hybrid	Rolland T (2014)	1
IL6ST	0	ERBB3	3	affinity chromatography technology	Grant SL (2002)	1
SLAMF1	2	INPP5D	2	affinity chromatography technology	Mikhalap SV (1999)	1
CBLB	3	KIT	4	affinity chromatography technology	Szymkiewicz I (2002)	1
PTPN11	20	PAF1	6	affinity chromatography technology, bioid	Takahashi A (2011), St-Denis N (2016)	2
MAPK14	0	BCAR1	6	affinity chromatography technology	Hein MY (2015)	1
GRB2	2	PDGFRB	8	pull down, pull down, affinity chromatography technology	Arvidsson AK (1994), Tang J (1997), Braverman LE (1999)	3
PTPN11	20	TXNIP	2	x-ray crystallography, pull down, x-ray crystallography, pull down	Liu Y (2016), Liu Y (2016), Liu S (2016), Liu S (2016)	4
FGFR4	6	PTPN6	0	two hybrid	Yao Z (2017)	1
5175	0	PIK3R1	6	affinity chromatography technology	Pellegatta F (1998)	1
PTK2	2	EPHA2	3	affinity chromatography technology	Miao H (2000)	1
CAV1	0	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Li Y (2008), Rodriguez DA (2009)	2
MAPK14	0	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CD33	2	PTPN11	20	affinity chromatography technology, pull down	Taylor VC (1999), Taylor VC (1999)	2
CRK	0	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, two hybrid	Gesbert F (1998), Husson H (1997), Ingham RJ (1996), Ingham RJ (1996), Delehanty LL (2003), Garcia-Guzman M (2000), Garcia-Guzman M (2000), Barber DL (1997), Buday L (1996), Sawasdikosol S (1996), Sawasdikosol S (1996), Thien CB (1997), van Leeuwen JE (1999), Ribon V (1996), Lottin-Divoux S (2006), Reedquist KA (1996), Brehme M (2009), Brehme M (2009), Ota S (1998), Peterson ME (2008), Liu BA (2012), Fukazawa T (1996), Umehara H (2002), Grossmann A (2015)	24
INSR	9	CAV1	0	affinity chromatography technology	Nystrom FH (1999)	1
ELAVL1	0	MED21	1	affinity chromatography technology	Abdelmohsen K (2009)	1
ERBB2	6	CRKL	1	unspecified method	Jones RB (2006)	1
PTPN11	20	RTF1	3	affinity chromatography technology	Takahashi A (2011)	1
ROR2	0	PTPN6	0	two hybrid	Yao Z (2017)	1
PDGFRB	8	PTPN11	20	two hybrid, pull down	Keilhack H (2001), Lechleider RJ (1993)	2
MAP3K5	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MED21	1	MPZL1	0	affinity chromatography technology	Huttlin EL (2017)	1
GOLGA2	2	NXT2	0	two hybrid	Rolland T (2014)	1
NTRK1	1	ROR2	0	affinity chromatography technology	Emdal KB (2015)	1
SRC	2	STAT3	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Cao X (1996), Cao X (1996), Yin N (2004), Yin N (2004), Jaganathan S (2011), Jaganathan S (2011), Gray MJ (2005), Schreiner SJ (2002)	8
PDGFRA	3	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IL4R	1	GOLGA2	2	affinity chromatography technology	Huttlin EL (2017)	1
FYN	1	PIK3R2	3	pull down	Gout I (1992)	1
GRB2	2	SYNCRIP	6	pull down	Fu C (1997)	1
HDAC6	0	JAK2	1	affinity chromatography technology	M L (2016)	1
CSF2RB	6	PTPN11	20	affinity chromatography technology, pull down	Bone H (1997), Bone H (1997)	2
NTRK1	1	ELAVL1	0	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	SOCS1	1	affinity chromatography technology	Xia L (2002)	1
GRB2	2	GAB1	3	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, far western blotting, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Oneyama C (2002), Lewitzky M (2001), Lewitzky M (2001), Lewitzky M (2001), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Bandyopadhyay S (2010), Ingham RJ (1998), Brehme M (2009), Fixman ED (1997), Bisson N (2011), Huttlin EL (2017), Kapoor GS (2010), Lehr S (1999)	15
CBLB	3	CRKL	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Elly C (1999), Elly C (1999), Grossmann A (2015)	3
ERBB2	6	PIK3R1	6	affinity chromatography technology, unspecified method	Crovello CS (1998), Jones RB (2006)	2
STAT3	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Gunaje JJ (2001), M L (2016)	2
GRB2	2	SOS1	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Liu SK (1998), Oneyama C (2002), Puil L (1994), Robinson A (1996), Li N (1993), Wong A (2002), Wong A (2002), Reif K (1994), DAngelo G (1999), Nel AE (1995), Pandey P (1995), Buday L (1994), Tong XK (2000), Park RK (1999), Okada S (1996), Okada S (1996), Okada S (1996), Germani A (1999), Park RK (1999), Chin H (1997), Saci A (2002), Sastry L (1997), Spivak-Kroizman T (1994), Ingham RJ (1996), Wang Y (1999), Chu J (1998), Brehme M (2009), Houtman JC (2006), Lao DH (2006), Bisson N (2011), Wang J (2011), Ng MY (2017), Huttlin EL (2017), Kapoor GS (2010), Saito T (2004), Klint P (1995)	37
GHR	1	SOCS3	0	pull down	Ram PA (1999)	1
TRIM25	5	SYNCRIP	6	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
IL6ST	0	SOCS3	0	affinity chromatography technology, pull down, pull down, enzymatic study	Lehmann U (2003), Lehmann U (2003), Schmitz J (2000), Kershaw NJ (2014)	4
GPX7	0	PTPN11	20	affinity chromatography technology	Huttlin EL (2017)	1
PTPN6	0	CAV1	0	affinity chromatography technology	Caselli A (2002)	1
HDAC6	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, imaging technique	M L (2016), M L (2016), M L (2016)	3
FCGR2B	3	PTPN11	20	affinity chromatography technology	Koncz G (1999)	1
ELAVL1	0	STAT3	0	affinity chromatography technology	Abdelmohsen K (2009)	1
EGFR	5	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marques MM (1999), Li J (2013), Li J (2013), Sharif A (2009)	4
TRIM25	5	DNM2	2	affinity chromatography technology	Choudhury NR (2017)	1
SOCS1	1	PTPN11	20	affinity chromatography technology	Ali S (2003)	1
STAT3	0	NXT2	0	two hybrid	Grossmann A (2015)	1
FGFR2	6	SRC	2	affinity chromatography technology	Schueller AC (2008)	1
EGFR	5	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Olayioye MA (1999), Xia L (2002), Andl CD (2004), Foerster S (2013), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	8
NTRK1	1	GAREM2	1	affinity chromatography technology	Emdal KB (2015)	1
CRK	0	FRS2	0	pull down	Meakin SO (1999)	1
FYN	1	CTNNB1	30	enzymatic study, imaging technique	Piedra J (2003), Chen TC (2014)	2
PTPN11	20	RANGRF	2	two hybrid	Daakour S (2016)	1
PTPN11	20	POU2AF1	1	two hybrid	Daakour S (2016)	1
EGFR	5	JAK1	6	affinity chromatography technology	Tong J (2008)	1
BTLA	0	PTPN11	20	affinity chromatography technology	Watanabe N (2003)	1
CSF2RB	6	PTPN6	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Bone H (1997), Bone H (1997), Yi T (1993), Yi T (1993)	4
KDR	4	CSF2RB	6	affinity chromatography technology, affinity chromatography technology	Dentelli P (2005), Dentelli P (2005)	2
IGF1R	5	IRS1	7	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Tartare-Deckert S (1995), Dey BR (1996), Dey BR (1996), Manes S (1999)	4
CRKL	1	MPZL1	0	affinity chromatography technology	Hein MY (2015)	1
PTPN11	20	WDR61	0	affinity chromatography technology	Takahashi A (2011)	1
GTF2E2	2	DNM2	2	affinity chromatography technology	Jeronimo C (2007)	1
PDGFRA	3	PDGFRB	8	affinity chromatography technology, pull down, affinity chromatography technology	Rupp E (1994), Seifert RA (1989), Huttlin EL (2017)	3
PIK3R2	3	CRK	0	affinity chromatography technology, affinity chromatography technology, two hybrid	Brehme M (2009), Brehme M (2009), Grossmann A (2015)	3
SOCS1	1	IGF1R	5	two hybrid	Dey BR (1998)	1
CRK	0	SRC	2	affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Garcia-Guzman M (2000)	2
ELAVL1	0	SOCS3	0	affinity chromatography technology	Do KH (2013)	1
GRB2	2	CRKL	1	affinity chromatography technology	Park RK (1999)	1
HDAC6	0	ERBB3	3	protein complementation assay	Deribe YL (2009)	1
NTRK1	1	CBLB	3	affinity chromatography technology, affinity chromatography technology	Emdal KB (2015), Emdal KB (2015)	2
STAT5B	3	PRLR	0	affinity chromatography technology	Ma L (2010)	1
KIT	4	CRKL	1	pull down, affinity chromatography technology	van Dijk TB (2000), Sattler M (1997)	2
SRC	2	KDR	4	affinity chromatography technology, affinity chromatography technology, unspecified method	Meyer RD (2008), Gavard J (2008), Sun Z (2012)	3
EPHA1	5	IQCB1	3	affinity chromatography technology	Huttlin EL (2017)	1
PTPN11	20	PNCK	1	two hybrid	Daakour S (2016)	1
TRIM25	5	RFWD2	0	affinity chromatography technology	Choudhury NR (2017)	1
PTPN11	20	KIT	4	pull down, affinity chromatography technology, unspecified method	Tauchi T (1994), Kozlowski M (1998), Wollberg P (2003)	3
PAF1	6	WDR61	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Kim J (2010), Mak AB (2010), Wu J (2012), Wan C (2015)	4