PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
EXOSC4	1	XRN2	1	genetic interference	Horlbeck MA (2018)	1
AICDA	0	KPNB1	3	affinity chromatography technology	Delker RK (2013)	1
HSPA5	0	KPNB1	3	biochemical	Havugimana PC (2012)	1
AICDA	0	PGAM1	0	affinity chromatography technology	Delker RK (2013)	1
EXOSC3	2	EXOSC5	0	two hybrid, affinity chromatography technology, biochemical, two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Raijmakers R (2002), Staals RH (2010), Havugimana PC (2012), Lehner B (2004), Lehner B (2004), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	9
EXOSC4	1	EXOSC9	2	affinity chromatography technology, biochemical, two hybrid, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tomecki R (2010), Havugimana PC (2012), Lehner B (2004), Lehner B (2004), Wan C (2015), Hein MY (2015), Hein MY (2015), Boldt K (2016)	8
CTNNBL1	1	RBM39	2	affinity chromatography technology	Ganesh K (2011)	1
EXOSC9	2	EXOSC10	1	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015)	3
AICDA	0	RTCB	1	affinity chromatography technology	Delker RK (2013)	1
DIS3	2	EXOSC1	0	affinity chromatography technology	Tomecki R (2010)	1
EXOSC7	0	EXOSC5	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	4
EXOSC5	0	EXOSC8	2	two hybrid, two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology	Raijmakers R (2002), Raijmakers R (2002), Lehner B (2004), Lehner B (2004), Rolland T (2014), Huttlin EL (2015), Wan C (2015), Yu H (2011), Hein MY (2015), Huttlin EL (2017)	10
EXOSC8	2	EXOSC9	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
AICDA	0	EXOSC6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Basu U (2011), Basu U (2011), Basu U (2011)	3
HSPA5	0	PRKDC	12	affinity chromatography technology	Hein MY (2015)	1
EXOSC3	2	EXOSC7	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Staals RH (2010), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	4
KPNA4	0	APP	1	pull down	Olah J (2011)	1
AICDA	0	EXOSC5	0	affinity chromatography technology, affinity chromatography technology	Basu U (2011), Basu U (2011)	2
AICDA	0	CCT7	2	affinity chromatography technology	Delker RK (2013)	1
AICDA	0	HERPUD2	0	affinity chromatography technology	Delker RK (2013)	1
RPA1	0	HNRNPA0	1	affinity chromatography technology	Marechal A (2014)	1
EXOSC1	0	EXOSC4	1	two hybrid, affinity chromatography technology, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Raijmakers R (2002), Tomecki R (2010), Lehner B (2004), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
KPNA4	0	AICDA	0	affinity chromatography technology	Patenaude AM (2009)	1
RNF126	2	NUP93	5	affinity chromatography technology	OConnor HF (2015)	1
DDX21	0	RBM39	2	biochemical	Havugimana PC (2012)	1
EXOSC6	0	EXOSC8	2	two hybrid, two hybrid, two hybrid, two hybrid	Raijmakers R (2002), Raijmakers R (2002), Lehner B (2004), Lehner B (2004)	4
EXOSC6	0	EXOSC1	0	two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Raijmakers R (2002), Raijmakers R (2002), Lehner B (2004), Hein MY (2015), Huttlin EL (2017)	5
EXOSC3	2	EXOSC9	2	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Staals RH (2010), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
EXOSC9	2	XRN2	1	genetic interference	Horlbeck MA (2018)	1
EXOSC7	0	EXOSC8	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AICDA	0	RNF126	2	affinity chromatography technology, biochemical, affinity chromatography technology, enzymatic study	Delker RK (2013), Delker RK (2013), Delker RK (2013), Delker RK (2013)	4
XPO1	8	XRN2	1	biochemical	Havugimana PC (2012)	1
EXOSC8	2	EXOSC10	1	two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Lehner B (2004), Lehner B (2004), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	5
KPNA1	5	CTNNBL1	1	affinity chromatography technology, affinity chromatography technology	Ganesh K (2011), Ganesh K (2011)	2
RAD51	3	EIF2D	0	affinity chromatography technology	Ewing RM (2007)	1
EXOSC1	0	EXOSC2	2	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	4
AICDA	0	EEF1A1	0	affinity chromatography technology	Delker RK (2013)	1
RPA1	0	RBM39	2	affinity chromatography technology	Marechal A (2014)	1
AICDA	0	EXOSC4	1	affinity chromatography technology, affinity chromatography technology	Basu U (2011), Basu U (2011)	2
EXOSC5	0	EXOSC10	1	biochemical, two hybrid, biochemical, affinity chromatography technology	Havugimana PC (2012), Lehner B (2004), Wan C (2015), Hein MY (2015)	4
AICDA	0	HNRNPA0	1	affinity chromatography technology	Delker RK (2013)	1
EXOSC7	0	EXOSC1	0	two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Raijmakers R (2002), Raijmakers R (2002), Raijmakers R (2002), Raijmakers R (2002), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	8
PPP2R1A	8	IER5	0	affinity chromatography technology	Yadav L (2017)	1
ACTG1	5	EEF1A1	0	biochemical	Wan C (2015)	1
PSME3	0	HSPA5	0	two hybrid	Stelzl U (2005)	1
DIS3	2	EXOSC2	2	affinity chromatography technology, biochemical	Tomecki R (2010), Wan C (2015)	2
XRN2	1	EEF1A1	0	two hybrid	Lehner B (2004)	1
CCT7	2	KPNA4	0	biochemical	Wan C (2015)	1
EXOSC3	2	DIS3	2	affinity chromatography technology	Staals RH (2010)	1
XPO1	8	PRKACA	2	affinity chromatography technology	Kirli K (2015)	1
AICDA	0	DDX19B	2	affinity chromatography technology	Delker RK (2013)	1
DIS3	2	AICDA	0	affinity chromatography technology	Basu U (2011)	1
DIS3	2	EXOSC7	0	affinity chromatography technology, biochemical	Tomecki R (2010), Wan C (2015)	2
EXOSC6	0	EXOSC10	1	two hybrid, two hybrid	Lehner B (2004), Lehner B (2004)	2
NEDD4L	3	UBE2L3	1	pull down, pull down, pull down, pull down, pull down	Bruce MC (2008), Schwarz SE (1998), Wauer T (2015), Michel MA (2015), Zhang W (2016)	5
TUBB4B	6	XPO1	8	biochemical, affinity chromatography technology	Havugimana PC (2012), Kirli K (2015)	2
EXOSC7	0	APP	1	pull down	Olah J (2011)	1
EXOSC8	2	EXOSC2	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	4
KPNA1	5	KPNB1	3	pull down, pull down, pull down, biochemical, affinity chromatography technology, pull down	Koehler M (1999), Percipalle P (1997), Plafker SM (2000), Havugimana PC (2012), Hein MY (2015), Tsujii A (2015)	6
AICDA	0	EIF2D	0	affinity chromatography technology	Delker RK (2013)	1
EXOSC1	0	EXOSC10	1	biochemical, affinity chromatography technology, affinity chromatography technology	Wan C (2015), Hein MY (2015), Huttlin EL (2017)	3
AICDA	0	TUBB4B	6	affinity chromatography technology	Wu X (2005)	1
XPO1	8	NEDD4L	3	affinity chromatography technology	Kirli K (2015)	1
AICDA	0	RRM2B	1	affinity chromatography technology	Delker RK (2013)	1
AICDA	0	NUP93	5	affinity chromatography technology	Delker RK (2013)	1
HSPA5	0	ACTG1	5	affinity chromatography technology	Li J (2013)	1
XPO1	8	EXOSC5	0	affinity chromatography technology	Kirli K (2015)	1
AICDA	0	EXOSC2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Basu U (2011), Basu U (2011), Basu U (2011)	3
AICDA	0	HAUS4	0	affinity chromatography technology	Delker RK (2013)	1
CTNNBL1	1	PPP2R1A	8	genetic interference	Horlbeck MA (2018)	1
EXOSC2	2	XRN2	1	genetic interference	Horlbeck MA (2018)	1
AICDA	0	UBE2L3	1	affinity chromatography technology	Delker RK (2013)	1
XPO1	8	HAUS4	0	affinity chromatography technology	Kirli K (2015)	1
RPA1	0	EXOSC10	1	affinity chromatography technology	Marechal A (2014)	1
AICDA	0	IER5	0	affinity chromatography technology	Delker RK (2013)	1
AICDA	0	HNRNPM	1	affinity chromatography technology	Delker RK (2013)	1
KPNA2	0	KPNA1	5	biochemical	Wan C (2015)	1
AICDA	0	ZMIZ2	1	affinity chromatography technology	Delker RK (2013)	1
KPNA2	0	KPNA4	0	biochemical, biochemical	Kristensen AR (2012), Wan C (2015)	2
PCNA	0	RPA1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ohta S (2002), Ogi T (2010), Takasaki Y (2001), Gong Z (2011), Miccoli L (2005), Han J (2014)	6
PCNA	0	FEN1	1	pull down, pull down, pull down, pull down, two hybrid, pull down, pull down, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, x-ray crystallography, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Hasan S (2001), Jonsson ZO (1998), Gary R (1997), Chen U (1996), Chen U (1996), Chen U (1996), Chen U (1996), Chen U (1996), Dianova II (2001), Dianova II (2001), Yu P (2001), Friedrich-Heineken E (2005), Wang SC (2006), Warbrick E (1997), Warbrick E (1997), Bruning JB (2004), Bruning JB (2004), Zhang Z (2012), Pichler G (2012), Takawa M (2012), Wu X (1996), Wu X (1996), Sakurai S (2005), Sharma S (2004), Han J (2014), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	30
KPNA2	0	APP	1	pull down	Olah J (2011)	1
RPA1	0	EXOSC7	0	affinity chromatography technology	Marechal A (2014)	1
KPNB1	3	KPNA2	0	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Nagoshi E (2001), Koehler M (1999), Kutay U (1997), Hein MY (2015), Huttlin EL (2017)	5
XRN2	1	EXOSC8	2	two hybrid	Lehner B (2004)	1
XPO1	8	DDX19B	2	biochemical	Wan C (2015)	1
AICDA	0	CPSF3	5	affinity chromatography technology	Delker RK (2013)	1
RNF126	2	DIS3	2	affinity chromatography technology	OConnor HF (2015)	1
RTCB	1	HNRNPM	1	biochemical, biochemical	Kristensen AR (2012), Wan C (2015)	2
FEN1	1	APP	1	pull down	Olah J (2011)	1
AICDA	0	KPNA1	5	affinity chromatography technology, affinity chromatography technology	Ganesh K (2011), Patenaude AM (2009)	2
RPA1	0	HSPA5	0	affinity chromatography technology	Marechal A (2014)	1
DIS3	2	EXOSC10	1	affinity chromatography technology, two hybrid, two hybrid, biochemical	Tomecki R (2010), Lehner B (2004), Lehner B (2004), Wan C (2015)	4
RPA1	0	EXOSC8	2	affinity chromatography technology	Marechal A (2014)	1
EXOSC9	2	EXOSC6	0	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
AICDA	0	CTNNBL1	1	affinity chromatography technology, affinity chromatography technology	Ganesh K (2011), Delker RK (2013)	2
AICDA	0	PRKACA	2	affinity chromatography technology	Basu U (2005)	1
AICDA	0	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
KPNB1	3	EXOSC2	2	biochemical	Wan C (2015)	1
PCNA	0	PRKDC	12	affinity chromatography technology	Ohta S (2002)	1
EXOSC3	2	APP	1	pull down	Olah J (2011)	1
AICDA	0	PRKDC	12	affinity chromatography technology, affinity chromatography technology, pull down	Wu X (2005), Wu X (2005), Wu X (2005)	3
EXOSC3	2	EXOSC8	2	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Staals RH (2010), Lehner B (2004), Lehner B (2004), Huttlin EL (2015), Huttlin EL (2017)	5
XPO1	8	IER5	0	affinity chromatography technology	Kirli K (2015)	1
PCNA	0	EEF1A1	0	affinity chromatography technology	Naryzhny SN (2010)	1
DIS3	2	EXOSC5	0	affinity chromatography technology	Tomecki R (2010)	1
PCNA	0	RAD51	3	affinity chromatography technology, imaging technique	Chen X (2016), Sato K (2016)	2
EXOSC9	2	AICDA	0	affinity chromatography technology	Basu U (2011)	1
XRN2	1	EXOSC10	1	two hybrid	Lehner B (2004)	1
EXOSC4	1	EXOSC6	0	affinity chromatography technology, biochemical, affinity chromatography technology	Tomecki R (2010), Wan C (2015), Hein MY (2015)	3
PCNA	0	PGAM1	0	affinity chromatography technology, pull down	Naryzhny SN (2010), Naryzhny SN (2010)	2
NEDD4L	3	AICDA	0	enzymatic study	Persaud A (2009)	1
EXOSC5	0	EXOSC9	2	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015), Hein MY (2015)	4
AICDA	0	ACTG1	5	affinity chromatography technology	Delker RK (2013)	1
EXOSC4	1	EXOSC8	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tomecki R (2010), Havugimana PC (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	5
AICDA	0	RBM39	2	affinity chromatography technology	Delker RK (2013)	1
RAD51	3	RPA1	0	pull down, two hybrid	Sugiyama T (2002), Du Y (2009)	2
KPNA4	0	KPNB1	3	pull down, affinity chromatography technology, affinity chromatography technology	Koehler M (1999), Hein MY (2015), Mukherjee S (2016)	3
RPA1	0	XRN2	1	affinity chromatography technology	Marechal A (2014)	1
RPA1	0	HNRNPM	1	affinity chromatography technology	Marechal A (2014)	1
EXOSC7	0	EXOSC10	1	two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Lehner B (2004), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	4
EXOSC7	0	EXOSC4	1	two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Raijmakers R (2002), Tomecki R (2010), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	8
CTNNBL1	1	DDX21	0	affinity chromatography technology	Ganesh K (2011)	1
EXOSC4	1	EXOSC5	0	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Tomecki R (2010), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Hein MY (2015)	5
EXOSC8	2	EXOSC1	0	two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Lehner B (2004), Lehner B (2004), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
DIS3	2	KPNB1	3	biochemical	Wan C (2015)	1
HNRNPM	1	HNRNPA0	1	biochemical	Havugimana PC (2012)	1
DIS3	2	EXOSC9	2	affinity chromatography technology, biochemical	Tomecki R (2010), Wan C (2015)	2
RPA1	0	TUBB4B	6	affinity chromatography technology	Marechal A (2014)	1
EXOSC4	1	EXOSC3	2	affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Tomecki R (2010), Staals RH (2010), Havugimana PC (2012), Lehner B (2004), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	8
EXOSC5	0	EXOSC1	0	two hybrid, pull down, two hybrid, two hybrid, two hybrid, two hybrid, two hybrid, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Raijmakers R (2002), Raijmakers R (2002), Raijmakers R (2002), Raijmakers R (2002), Venkatesan K (2009), Lehner B (2004), Lehner B (2004), Rolland T (2014), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	12
XPO1	8	RTCB	1	affinity chromatography technology	Kirli K (2015)	1
PPP2R1A	8	EEF1A1	0	affinity chromatography technology, affinity chromatography technology	Aranda-Orgilles B (2008), Aranda-Orgilles B (2008)	2
KPNA2	0	AICDA	0	affinity chromatography technology	Patenaude AM (2009)	1
AICDA	0	XPO1	8	affinity chromatography technology	Patenaude AM (2009)	1
DDX19B	2	APP	1	pull down	Olah J (2011)	1
XRN2	1	KPNA1	5	affinity chromatography technology	Li S (2014)	1
AICDA	0	PCNA	0	affinity chromatography technology	Basu U (2011)	1
EXOSC4	1	EEF1A1	0	two hybrid	Lehner B (2004)	1
EXOSC3	2	EXOSC2	2	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Staals RH (2010), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
EXOSC3	2	EXOSC10	1	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Staals RH (2010), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	5
AICDA	0	FEN1	1	affinity chromatography technology	Delker RK (2013)	1
AICDA	0	EXOSC7	0	affinity chromatography technology, affinity chromatography technology	Basu U (2011), Basu U (2011)	2
PSME3	0	AICDA	0	affinity chromatography technology, pull down	Uchimura Y (2011), Uchimura Y (2011)	2
AICDA	0	AICDA	0	affinity chromatography technology, affinity chromatography technology	Patenaude AM (2009), Delker RK (2013)	2
EXOSC2	2	EXOSC5	0	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015), Hein MY (2015)	4
AICDA	0	XRN2	1	affinity chromatography technology	Delker RK (2013)	1
CTNNBL1	1	KPNA2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganesh K (2011), Ganesh K (2011), Ganesh K (2011)	3
XPO1	8	HNRNPM	1	affinity chromatography technology	Kirli K (2015)	1
PRKDC	12	RPA1	0	pull down, affinity chromatography technology, affinity chromatography technology	Shao RG (1999), Gong Z (2011), Marechal A (2014)	3
RTCB	1	PRKDC	12	biochemical	Kristensen AR (2012)	1
DAZAP2	1	NEDD4L	3	two hybrid	Rolland T (2014)	1
AICDA	0	HSPA5	0	affinity chromatography technology	Delker RK (2013)	1
EXOSC8	2	AICDA	0	affinity chromatography technology	Basu U (2011)	1
DIS3	2	EXOSC4	1	affinity chromatography technology, biochemical	Tomecki R (2010), Wan C (2015)	2
AICDA	0	RAD51	3	affinity chromatography technology	Delker RK (2013)	1
AICDA	0	DDX21	0	affinity chromatography technology	Delker RK (2013)	1
EXOSC2	2	EXOSC10	1	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
EXOSC9	2	EXOSC1	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	4
AICDA	0	DAZAP2	1	affinity chromatography technology	Delker RK (2013)	1
EXOSC6	0	EXOSC7	0	two hybrid, two hybrid, biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology	Raijmakers R (2002), Raijmakers R (2002), Havugimana PC (2012), Lehner B (2004), Huttlin EL (2015), Huttlin EL (2017)	6
EEF1A1	0	RTCB	1	biochemical	Wan C (2015)	1
AICDA	0	RPA1	0	affinity chromatography technology	Delker RK (2013)	1
EXOSC3	2	EXOSC6	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Staals RH (2010), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	4
EXOSC7	0	EXOSC9	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	5
EXOSC2	2	EXOSC6	0	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
PPP2R1A	8	RAD51	3	genetic interference	Horlbeck MA (2018)	1
EXOSC3	2	EXOSC1	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Staals RH (2010), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
AICDA	0	EXOSC3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Basu U (2011), Basu U (2011), Basu U (2011)	3
EXOSC2	2	EXOSC4	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Raijmakers R (2002), Raijmakers R (2002), Raijmakers R (2002), Tomecki R (2010), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Hein MY (2015), Boldt K (2016)	9
EXOSC4	1	EXOSC10	1	affinity chromatography technology, biochemical, two hybrid, two hybrid, biochemical, affinity chromatography technology	Tomecki R (2010), Havugimana PC (2012), Lehner B (2004), Lehner B (2004), Wan C (2015), Hein MY (2015)	6
EXOSC2	2	EXOSC7	0	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Raijmakers R (2002), Raijmakers R (2002), Lehner B (2004), Lehner B (2004), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	9
CCT7	2	APP	1	pull down	Olah J (2011)	1
EXOSC5	0	EXOSC6	0	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
RPA1	0	EEF1A1	0	affinity chromatography technology	Marechal A (2014)	1
DIS3	2	EXOSC8	2	affinity chromatography technology, two hybrid	Tomecki R (2010), Lehner B (2004)	2
RBM39	2	APP	1	pull down	Olah J (2011)	1
EXOSC2	2	EXOSC9	2	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015), Hein MY (2015), Boldt K (2016)	5
EXOSC10	1	AICDA	0	affinity chromatography technology	Basu U (2011)	1
KPNB1	3	NUP93	5	affinity chromatography technology	Hein MY (2015)	1
EXOSC1	0	APP	1	pull down	Olah J (2011)	1
AICDA	0	EXOSC1	0	affinity chromatography technology, affinity chromatography technology	Basu U (2011), Basu U (2011)	2
AICDA	0	PPP2R1A	8	affinity chromatography technology	Delker RK (2013)	1