Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
NUP107 rs79419059 C Platinum compounds efficacy yes In the cohort, 25 patients received carboplatin-based first line therapy and 3 received cisplatin therapy. Controlling for other con-founders, multivariate age-adjusted Cox proportional hazard analysis showed that the variant rs79419059 was significantly associated with platinum resistance [odds ratio: 4.519, 95% confidence interval (CI): 1.317–15.501, P = 0.0457]. Allele C is associated with increased resistance to Platinum compounds in women with Ovarian Neoplasms as compared to allele T. 28562428 1448635633