Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
PPM1A 5494 NORTRIPTYLINE CHEMBL445 PharmGKB

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
PPM1A rs2273623 AA nortriptyline efficacy yes Effect was apparent after 5 weeks of treatment. Genotype AA is associated with decreased response to nortriptyline in people with Depression as compared to genotypes AG + GG. 20970119 827777144