Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
ERAP1 51752 TOSEDOSTAT CHEMBL2103847 inhibitor ChemblInteractions

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
ERAP1 rs27524 AA etanercept efficacy no Response was based on the change in PASI score before and after 3 months of treatment. PASI = psoriasis area and severity index. Genotype AA is not associated with response to etanercept in people with Psoriasis as compared to genotype GG. 27564082 1448264054
ERAP1 rs27524 AA ustekinumab efficacy no Response was based on the change in PASI score before and after 3 months of treatment. PASI = psoriasis area and severity index. Genotype AA is not associated with response to ustekinumab in people with Psoriasis as compared to genotype GG. 27564082 1448264066
ERAP1 rs27524 AA adalimumab efficacy no Response was based on the change in PASI score before and after 3 months of treatment. PASI = psoriasis area and severity index. Genotype AA is not associated with response to adalimumab in people with Psoriasis as compared to genotype GG. 27564082 1448264060