PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TP53	0	TP73	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Stindt MH (2015), Puca R (2011), De Laurenzi V (1998), Di Como CJ (1999)	4
CCNA2	1	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
LYN	2	CREBBP	29	pull down	Whiting RJ (2012)	1
SP1	0	TBP	0	two hybrid, two hybrid, pull down, pull down	Loregian A (2003), Loregian A (2003), Schwarzenbach H (2014), Schwarzenbach H (2014)	4
TAF6	4	TAF12	0	two hybrid	Bando M (1997)	1
NFYB	2	CORO1B	6	biochemical	Wan C (2015)	1
SP1	0	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, two hybrid, imaging technique, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Gao J (2009), Goto T (2006), Hung JJ (2006), Hung JJ (2006), Hung JJ (2006), Choi HS (2002), Walker GE (2001), Kundu TK (2000), Suzuki T (2000), Suzuki T (2000), Wang X (2008), Wang X (2008), Wang X (2008), Chen YJ (2007), Chen YJ (2007), Azahri NS (2012), Azahri NS (2012), Li J (2013), Li J (2013), Wang SA (2014)	20
NFYC	0	CORO1B	6	biochemical	Wan C (2015)	1
CREBBP	29	NFYB	2	affinity chromatography technology	Leclerc GJ (2010)	1
KAT2B	2	NFYC	0	affinity chromatography technology, affinity chromatography technology	Uramoto H (2004), Uramoto H (2004)	2
GRB2	2	NFYB	2	two hybrid	Bandyopadhyay S (2010)	1
EP300	36	NFYB	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology	Uramoto H (2004), Uramoto H (2004), Li Q (1998), Faniello MC (1999), Faniello MC (1999)	5
MAOB	1	NFYB	2	two hybrid	Wang J (2011)	1
TP53	0	TAF6	4	pull down, affinity chromatography technology, affinity chromatography technology	Wilhelm E (2010), Wilhelm E (2010), Wilhelm E (2010)	3
TBP	0	CREBBP	29	affinity chromatography technology	Dallas PB (1997)	1
NFYA	2	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Imbriano C (2005), Imbriano C (2005), Imbriano C (2005), Di Agostino S (2006), Di Agostino S (2006), Huang X (2013)	6
MYC	2	TBP	0	pull down	McEwan IJ (1996)	1
TBP	0	NFYC	0	pull down	Bellorini M (1997)	1
GRB2	2	EP300	36	two hybrid	Bandyopadhyay S (2010)	1
CREBBP	29	TP73	2	pull down, pull down	Zeng X (2000), Lemasson I (2001)	2
TAF11	0	TAF6	4	affinity chromatography technology	Gupta K (2017)	1
SP1	0	NFYA	2	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Roder K (1999), Roder K (1999), Roder K (1999), Roder K (1999), Wang W (1999)	5
NFYA	2	CCNA2	1	pull down	Yun J (2003)	1
MYC	2	EP300	36	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, enzymatic study, affinity chromatography technology, affinity chromatography technology	Faiola F (2005), Faiola F (2005), Faiola F (2005), Faiola F (2005), Faiola F (2005), Zhang K (2005), Covic M (2005), Fujii M (2006)	8
EP300	36	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Han Y (2008), Mayanil CS (2006), Simone C (2004), Simone C (2004), Simone C (2004), Liu Y (2012), Mizuguchi Y (2012)	7
LYN	2	TP53	0	affinity chromatography technology, affinity chromatography technology	Ren X (2003), Ren X (2003)	2
TBP	0	TAF12	0	pull down, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, pull down	Knuesel MT (2009), Liu X (2008), Denissov S (2007), Wieczorek E (1998), Hoffmann A (1996), Hoffmann A (1996)	6
MYC	2	EIF4A1	3	affinity chromatography technology	Koch HB (2007)	1
NFYC	0	NFYB	2	two hybrid, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Wang J (2011), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
NFYB	2	LAGE3	0	biochemical	Wan C (2015)	1
NFYC	0	NFYA	2	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Bandyopadhyay S (2010), Yun J (2003), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	5
EP300	36	KAT2B	2	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Kim JH (2011), Lee M (2010), Santos-Rosa H (2003), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996), Mizuguchi Y (2012)	8
CCNE1	1	TP73	2	enzymatic study, pull down	Gaiddon C (2003), Gaiddon C (2003)	2
NFYA	2	TAF12	0	pull down	Frontini M (2002)	1
NFYB	2	SMYD3	0	two hybrid	Wang J (2011)	1
TP73	2	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Uramoto H (2002), Uramoto H (2002), Uramoto H (2002), Watanabe K (2002), Watanabe K (2002)	5
KAT2B	2	NFYB	2	affinity chromatography technology, affinity chromatography technology	Uramoto H (2004), Uramoto H (2004)	2
CDK2	0	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
TAF11	0	TAF12	0	affinity chromatography technology	Gupta K (2017)	1
NFYB	2	POLE4	0	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
TBP	0	EP300	36	affinity chromatography technology	Dallas PB (1997)	1
CEBPZ	4	NFYB	2	two hybrid, pull down	Imbriano C (2001), Imbriano C (2001)	2
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
CREBBP	29	NFATC2	1	pull down, pull down	Garcia-Rodriguez C (1998), Falvo JV (2008)	2
CDK2	0	NFYA	2	enzymatic study, pull down, affinity chromatography technology	Yun J (2003), Yun J (2003), Yun J (2003)	3
EIF4A1	3	LAGE3	0	biochemical	Wan C (2015)	1
CDK2	0	NFYC	0	affinity chromatography technology	Yun J (2003)	1
CCNA2	1	EP300	36	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HDAC1	4	TBP	0	affinity chromatography technology	Wu Y (2001)	1
TBP	0	TAF11	0	biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, biochemical, biochemical, pull down, affinity chromatography technology	Bellorini M (1997), Mengus G (1995), May M (1996), Knuesel MT (2009), Liu X (2008), Demeny MA (2007), Wieczorek E (1998), Brand M (1999), Gupta K (2017), Gupta K (2017)	10
TAF6	4	HDAC1	4	affinity chromatography technology	Nakamura T (2002)	1
NFYB	2	TAF6	4	pull down	Frontini M (2002)	1
NFYB	2	AGTRAP	1	two hybrid	Rolland T (2014)	1
NFYB	2	TAF11	0	pull down, pull down	Frontini M (2002), Frontini M (2002)	2
TP53	0	EP300	36	pull down, genetic interference, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, unspecified method, affinity chromatography technology, enzymatic study, unspecified method, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, unspecified method	An W (2004), Pastorcic M (2000), Livengood JA (2002), Livengood JA (2002), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Tang Y (2008), Wang H (2008), Valbuena A (2008), Shi D (2009), Vega FM (2004), Finlan L (2004), Groenroos E (2004), Zhao Y (2006), Roe JS (2006), Pedeux R (2005), Sekaric P (2007), Pan X (2009), Tang Y (2006), Sen GS (2011), Li Y (2012), Li Y (2012), Gillotin S (2010), Grossman SR (2003), Issaeva N (2004), Kitagawa M (2008), Sabbatini P (2002), Burge S (2009), Zilfou JT (2001), Issaeva N (2004), Issaeva N (2004), Feng H (2009), Feng H (2009), Lill NL (1997), Dornan D (2004), Dornan D (2004), Di Agostino S (2006), Wells M (2008), Fath DM (2006), Kobet E (2000), Costanzo A (2002), Kumazawa T (2011), Borger DR (2006), Cui D (2013), Borger DR (2006), Lee SJ (2013), Tang HY (2006), Lin C (2011), Choi WI (2014), Ding G (2013), Kim MK (2013), Ali A (2013), Wu G (2014), Mizuguchi Y (2012), Sinha S (2012), Sinha S (2012), Her YR (2013), Her YR (2013), Wu SY (2009), Wu SY (2009), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Gu W (1997), Teufel DP (2007), Mantovani F (2007), Mantovani F (2007), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), MacPartlin M (2005), Mujtaba S (2004), Wang YH (2003), Chen H (1999), Tang Z (2013), Graczyk A (2013), Graczyk A (2013), Chan HM (2001), Thomas MC (2005), Miller Jenkins LM (2015), Miller Jenkins LM (2015), Koh DI (2014), Koh DI (2014), Koh DI (2014), Li H (2015), Chen LF (2005), Shi D (2016), Wright DG (2016), Zhang X (2016), Procopio MG (2015), Tong Q (2015)	95
NFATC2	1	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Garcia-Rodriguez C (1998), Garcia-Rodriguez C (1998), Gabriel CH (2016), Gabriel CH (2016)	4
NFYB	2	MYC	2	affinity chromatography technology, pull down	Izumi H (2001), Izumi H (2001)	2
KAT2B	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study	Jin Y (2002), Wang H (2008), Zhao Y (2006), Roe JS (2006), Perez RE (2010), Tang Y (2006), Zhao LY (2003), Liu L (1999), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Harrod R (2003), MacPartlin M (2005), Chen H (1999), Kang H (2009)	15
NFATC2	1	NFYC	0	affinity chromatography technology	Gabriel CH (2016)	1
MYC	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LYN	2	NFYB	2	affinity chromatography technology	Zhu J (2013)	1
CDK2	0	EIF4A1	3	affinity chromatography technology	Neganova I (2011)	1
TP53	0	NFYB	2	affinity chromatography technology, affinity chromatography technology	Imbriano C (2005), Di Agostino S (2006)	2
NFYA	2	HDAC1	4	affinity chromatography technology	Ahn J (2011)	1
OSGEP	1	LAGE3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, biochemical, affinity chromatography technology	Ewing RM (2007), Costessi A (2012), Costessi A (2012), Costessi A (2012), Costessi A (2012), Costessi A (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	9
NFYB	2	CCNA2	1	affinity chromatography technology	Yun J (2003)	1
NFYA	2	NFYB	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, biochemical, affinity chromatography technology	Mantovani R (1994), Hu Q (2006), Imbriano C (2005), Yun J (2003), Rolland T (2014), Wan C (2015), Hein MY (2015)	7
TP53	0	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Borellini F (1993), Jin W (2008), Dhar SK (2006), Lagger G (2003), Lagger G (2003), Lagger G (2003), Lagger G (2003), Sengupta S (2005), Sengupta S (2005), Lin RK (2010), Kim HA (2011), Sawaya BE (1998), St Clair S (2004), Innocente SA (2005), Innocente SA (2005), Ohlsson C (1998), Kong X (2013), Bocangel D (2009), Bocangel D (2009)	19
CREBBP	29	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goto T (2006), Leclerc GJ (2010), Chuang JY (2012), Guo W (2014)	4
CREBBP	29	NFYA	2	affinity chromatography technology, affinity chromatography technology	Huang X (2013), Huang X (2013)	2
CREBBP	29	TP53	0	enzymatic study, pull down, genetic interference, pull down, enzymatic study, fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, imaging technique, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, affinity chromatography technology, unspecified method, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, enzymatic study, enzymatic study, pull down, x-ray crystallography, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Ito A (2002), Livengood JA (2002), Livengood JA (2002), Giebler HA (2000), Tang Y (2008), Jenkins LM (2009), Shi D (2009), Zhao Y (2006), Saifudeen Z (2005), Scolnick DM (1997), Scolnick DM (1997), Gu W (1997), Gu W (1997), Matsuda S (2004), Pasqualucci L (2011), Lee SK (1999), Dai C (2011), Lee CW (2010), Ferreon JC (2009), Ruas JL (2010), Ruas JL (2010), Huang WC (2007), Huang WC (2007), Mujtaba S (2004), Mujtaba S (2004), Mujtaba S (2004), Mujtaba S (2004), Col E (2002), Jansma AL (2014), Jansma AL (2014), Krois AS (2016), Hasegawa K (2008), Huang X (2013), Huang X (2013), Piskacek M (2016)	35
KAT2B	2	TAF12	0	affinity chromatography technology, affinity chromatography technology	Ogryzko VV (1998), Ogryzko VV (1998)	2
SP1	0	CCNA2	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Wang CH (2006), Fojas de Borja P (2001), Haidweger E (2001), Haidweger E (2001)	4
NFYC	0	MYC	2	pull down, two hybrid, affinity chromatography technology	Taira T (1999), Taira T (1999), Taira T (1999)	3
HDAC1	4	TP73	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Uramoto H (2004), Uramoto H (2004), Uramoto H (2004), Zhang J (2007)	4
KAT2B	2	MYC	2	enzymatic study	Patel JH (2004)	1
EIF4A1	3	NFYB	2	biochemical	Wan C (2015)	1
TP73	2	KAT2B	2	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao LY (2003), Zhao LY (2003), Zhao LY (2003), Zhao LY (2003), Hoffmann A (2008)	5
CDK2	0	SP1	0	enzymatic study	Fojas de Borja P (2001)	1
MYC	2	CDK2	0	genetic interference, genetic interference	Toyoshima M (2012), Zhou Z (2014)	2
TBP	0	TAF6	4	affinity chromatography technology, biochemical, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Pointud JC (2003), Bellorini M (1997), Ruppert S (1993), Knuesel MT (2009), Nakamura T (2002), Liu X (2008), Demeny MA (2007), Dikstein R (1996), Wieczorek E (1998), Dantonel JC (1997), Kamileri I (2012), Havugimana PC (2012), Soutoglou E (2005), Ogryzko VV (1998)	14
NFATC2	1	HDAC1	4	affinity chromatography technology	Gabriel CH (2016)	1
CCNA2	1	TAF11	0	affinity chromatography technology	Hein MY (2015)	1
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
NFYC	0	TAF11	0	pull down, pull down	Frontini M (2002), Frontini M (2002)	2
NFYA	2	EP300	36	affinity chromatography technology, affinity chromatography technology	Ahn J (2011), Di Agostino S (2006)	2
NFYC	0	TAF6	4	pull down	Frontini M (2002)	1
CDK2	0	TP73	2	enzymatic study	Gaiddon C (2003)	1
CEBPZ	4	TP53	0	affinity chromatography technology, pull down	Uramoto H (2003), Uramoto H (2003)	2
HDAC1	4	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Matsuoka Y (2008), Matsuoka Y (2008), Liu T (2007), Liu T (2007), Liu T (2007), Koch HB (2007), Hwang IY (2012), Hein MY (2015)	8
TP73	2	EP300	36	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Strano S (2005), Uramoto H (2004), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Mantovani F (2004), Burge S (2009), Burge S (2009), Costanzo A (2002), Hoffmann A (2008), Kramer D (2015)	13
HDAC1	4	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mayanil CS (2006), Chuang HC (2006), Chuang HC (2006)	3
NFYC	0	SP1	0	two hybrid	Bandyopadhyay S (2010)	1
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
NFYC	0	TAF12	0	pull down	Frontini M (2002)	1
TBP	0	NFYB	2	affinity chromatography technology, pull down	Bellorini M (1997), Bellorini M (1997)	2
NFYC	0	HDAC1	4	affinity chromatography technology	Kato T (2009)	1
TP53	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique	Ito A (2002), Wang C (2005), Dohi Y (2008), Jin W (2008), Lei Q (2006), Wu Y (2001), Wu Y (2001), Luo J (2000), Juan LJ (2000), Juan LJ (2000), Juan LJ (2000), Murphy M (1999), Insinga A (2004), Sun JM (2007), Yu XY (2010), Sinha S (2010), Sinha S (2010), Li Y (2012), Di Agostino S (2006), Pavithra L (2009), Pavithra L (2009), Luo J (2000), Chen TC (2014), Park EK (2015), Park EK (2015), Park EK (2015)	26
CCNA2	1	TAF6	4	affinity chromatography technology	Hein MY (2015)	1
NFYB	2	CCNE1	1	affinity chromatography technology	Yun J (2003)	1
NFYB	2	SP1	0	affinity chromatography technology	Leclerc GJ (2010)	1
OSGEP	1	NFYB	2	biochemical	Wan C (2015)	1
TBP	0	TP53	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Seto E (1992), Cvekl A (1999), Wu Y (2001), Qadri I (2002), Qadri I (2002), Sommer MH (1994)	6
NFATC2	1	NFYB	2	affinity chromatography technology	Gabriel CH (2016)	1
CCNA2	1	TP53	0	pull down	Luciani MG (2000)	1
CREBBP	29	KAT2B	2	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Tini M (2002), Cho H (1998), Cho H (1998), Cho H (1998), Korzus E (1998), Korzus E (1998), Korzus E (1998), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996)	10
NFYA	2	TAF6	4	pull down	Frontini M (2002)	1
NFYB	2	TP73	2	affinity chromatography technology, affinity chromatography technology	Hackzell A (2002), Uramoto H (2004)	2
CEBPZ	4	TP73	2	affinity chromatography technology, pull down	Uramoto H (2003), Uramoto H (2003)	2
MYC	2	TAF12	0	pull down	Liu X (2003)	1
CCNA2	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Naderi S (2005), Varshochi R (2005), Di Fiore B (2010), Mateo F (2009), Abbas T (2007), Schulman BA (1998), Datta NS (1998), Wu G (1997), Sebastian B (1993), Liu S (2009), Ciarallo S (2002), Wolthuis R (2008), Vicent GP (2011), Zhang H (1995), Sayle KL (2003), Jeffrey PD (1995), Davies TG (2001), Cook A (2002), Pevarello P (2006), Levkau B (1998), Poon RY (1996), OConnor PM (1993), Davies TG (2002), Kontopidis G (2003), Andrews MJ (2004), Pevarello P (2004), Pevarello P (2005), Varjosalo M (2013), Varjosalo M (2013), Kikuchi R (2014), Kikuchi R (2014), Mateo F (2009), So J (2015), Okamoto K (2002), Song MS (2011), Huttlin EL (2015), Di Fiore B (2015), Pan ZQ (1993), Pan ZQ (1993), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	43
CDK2	0	LYN	2	affinity chromatography technology	Mou S (1999)	1
KAT2B	2	CCNA2	1	affinity chromatography technology, pull down, enzymatic study	Mateo F (2009), Mateo F (2009), Mateo F (2009)	3
CREBBP	29	CCNE1	1	affinity chromatography technology	Wang A (2004)	1
NFYB	2	TAF12	0	pull down	Frontini M (2002)	1
SP1	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Di Padova M (2003), Singh J (2002), Zhang Y (2002), Sun JM (2002), Gao J (2009), Shon JK (2009), Mottet D (2009), Goto T (2006), Hung JJ (2006), Lagger G (2003), Choi HS (2002), Choi HS (2002), Kang JE (2005), Kang JE (2005), Kang JE (2005), Gan Y (2005), Gan Y (2005), Duan H (2005), Varshochi R (2005), Varshochi R (2005), Plaisance V (2005), Walker GE (2001), Walker GE (2001), Ammanamanchi S (2004), Doetzlhofer A (1999), Sekhavat A (2007), Liu T (2007), Enya K (2008), Liu S (2010), Leclerc GJ (2010), Leclerc GJ (2010), Wong CY (2011), Schnur N (2007)	33
NFYB	2	HDAC1	4	affinity chromatography technology	Leclerc GJ (2010)	1
EP300	36	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Felzien LK (1999), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
DRAP1	2	TBP	0	x-ray crystallography, affinity chromatography technology, pull down	Kamada K (2001), Gilfillan S (2005), Wang YL (2008)	3
CDK2	0	NFYB	2	affinity chromatography technology, affinity chromatography technology	Yun J (2003), Yun J (2003)	2
SP1	0	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Gartel AL (2001), Liu T (2007), Gordan JD (2007), Gordan JD (2007), Koshiji M (2005), Koshiji M (2005)	6
CREBBP	29	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, enzymatic study	de Nigris F (2007), de Nigris F (2007), Vervoorts J (2003), Vervoorts J (2003), Vervoorts J (2003), Vervoorts J (2003), Vervoorts J (2003)	7
CCNA2	1	TP73	2	enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Gaiddon C (2003), Gaiddon C (2003), Gaiddon C (2003), Gaiddon C (2003)	4
NFYA	2	TAF11	0	pull down	Frontini M (2002)	1
NFYB	2	DRAP1	2	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
KAT2B	2	CDK2	0	pull down, affinity chromatography technology, enzymatic study	Mateo F (2009), Mateo F (2009), Mateo F (2009)	3
NFYC	0	TP73	2	affinity chromatography technology, affinity chromatography technology	Hackzell A (2002), Uramoto H (2004)	2
CCNE1	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McKenzie PP (2003), Shanahan F (1999), Koff A (1992), Koff A (1992), Mayer C (2004), Connor MK (2003), Boudrez A (2000), Varshochi R (2005), Jeong JH (2010), Bustany S (2011), Yeh ES (2006), Hui S (2011), Kim J (2007), Kiviharju-af Haellstroem TM (2007), Abbas T (2007), Nishimura T (2005), Matsumoto Y (2004), Harwell RM (2004), Harwell RM (2004), Peiretti A (2003), Peiretti A (2003), Kim YB (2000), Manenti S (1999), Datta NS (1998), Sheaff RJ (1997), Higashi H (1996), Higashi H (1996), Musgrove EA (1996), Vlach J (1996), Grim JE (2008), Liu S (2009), Ciarallo S (2002), Desai D (1995), Baydoun HH (2010), Baydoun HH (2010), Chu I (2007), Chu I (2007), Levkau B (1998), Poon RY (1996), Zhao J (1998), Zhao J (1998), Larrea MD (2009), Varjosalo M (2013), Varjosalo M (2013), Chan HM (2001), So J (2015), Ungermannova D (2005), Song MS (2011), Huttlin EL (2015), Hein MY (2015), Lin CH (2015), Lin CH (2015), Davis RJ (2017), Huttlin EL (2017)	54