Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
AQP9 366 UREA CHEMBL985 NCI 12594337
AQP9 366 PHLORETIN CHEMBL45068 inhibitor GuideToPharmacologyInteractions
AQP9 366 FLUTAMIDE CHEMBL806 NCI 12021052
AQP9 366 TESTOSTERONE CHEMBL386630 NCI 12002438, 12021052
AQP9 366 STANOLONE CHEMBL27769 NCI 15850448

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
AQP9 rs1867380 A platinum efficacy no 26 SNPs were selected which satisfied the following criteria: 1) SNPs were from HapMap Project Phase II of the Han Chinese population 2) were haplotype tagger SNPs 3) SNP minor allele frequency was higher than 5% in Han Chinese 4) the pairwise linkage disequilibrium correlation coefficient (r-squared) was greater than 0.8. After Bonferroni corrections no SNPs remained significantly associated with platinum drug efficacy. Allele A is not associated with response to platinum in people with Lung Neoplasms as compared to allele G. 24643204 1184756063
AQP9 rs1516400 A platinum efficacy no 26 SNPs were selected which satisfied the following criteria: 1) SNPs were from HapMap Project Phase II of the Han Chinese population 2) were haplotype tagger SNPs 3) SNP minor allele frequency was higher than 5% in Han Chinese 4) the pairwise linkage disequilibrium correlation coefficient (r-squared) was greater than 0.8. After Bonferroni corrections no SNPs remained significantly associated with platinum drug efficacy. Allele A is not associated with response to platinum in people with Lung Neoplasms as compared to allele G. 24643204 1184756068
AQP9 rs1554203 A platinum efficacy no 26 SNPs were selected which satisfied the following criteria: 1) SNPs were from HapMap Project Phase II of the Han Chinese population 2) were haplotype tagger SNPs 3) SNP minor allele frequency was higher than 5% in Han Chinese 4) the pairwise linkage disequilibrium correlation coefficient (r-squared) was greater than 0.8. After Bonferroni corrections no SNPs remained significantly associated with platinum drug efficacy. Allele A is not associated with response to platinum in people with Lung Neoplasms as compared to allele G. 24643204 1184756073