PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CLEC4G	0	PKLR	0	two hybrid	Wang J (2008)	1
CLEC4G	0	MAP3K11	7	two hybrid	Wang J (2008)	1
CLEC4G	0	FTL	0	two hybrid	Wang J (2008)	1
CLEC4G	0	RPSA	2	two hybrid	Wang J (2008)	1
CLEC4G	0	WBP2	0	two hybrid	Wang J (2008)	1
CLEC4G	0	AZU1	0	two hybrid	Wang J (2008)	1
GEM	1	CLEC4G	0	two hybrid	Wang J (2008)	1
GEM	1	APOH	0	two hybrid	Wang J (2008)	1
CLEC4G	0	NUP214	3	two hybrid	Wang J (2008)	1
CLEC4G	0	IFI35	1	affinity chromatography technology, two hybrid	Wang J (2008), Wang J (2008)	2
CLEC4G	0	PRDX1	1	two hybrid	Wang J (2008)	1
CLEC4G	0	CAPN1	3	two hybrid	Wang J (2008)	1
CLEC4G	0	ASGR1	0	two hybrid	Wang J (2008)	1
CLEC4G	0	ARSA	1	two hybrid	Wang J (2008)	1
CLEC4G	0	APOH	0	two hybrid	Wang J (2008)	1
CLEC4G	0	SHBG	0	two hybrid	Wang J (2008)	1
CLEC4G	0	APOA1	0	two hybrid	Wang J (2008)	1
CLEC4G	0	EIF3I	0	two hybrid, affinity chromatography technology	Wang J (2008), Wang J (2008)	2
CLEC4G	0	COX1	0	two hybrid	Wang J (2008)	1
CLEC4G	0	CPN1	1	two hybrid	Wang J (2008)	1
EIF6	2	CAPN1	3	biochemical	Kristensen AR (2012)	1
CLEC4G	0	EIF6	2	two hybrid	Wang J (2008)	1