Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
ADH7 131 CHEMBL1161866 CHEMBL1161866 DrugBank 17608724, 17139284, 17016423, 8490052, 11410692
ADH7 131 ALCOHOL CHEMBL545 PharmGKB

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
ADH7 rs1154461 C ethanol "toxicity","metabolism/PK" yes The authors did not report p-value correction for multiple hypotheses (103 snps tested). Though they report multiple snps are significantly associated with alcohol metabolism (early or late) tested on blood or breath alcohol concentrations, this is the only snp that survived Bonferroni correction for multiple hypotheses (<0.00049). It was only significant for blood early metabolism, and the authors did not state which alleles are associated with increased or decreased metabolism. Instead, they simply report an association with the snp in general. Note that this gene is on the minus strand. Allele C is associated with metabolism of ethanol. 19193628 827566611