Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
AKR1C4 1109 CHEMBL1161866 CHEMBL1161866 DrugBank 17139284, 17016423, 11037109

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
AKR1C4 rs17134592 CG + GG exemestane metabolism/PK no No significant difference in exemestane concentrations were seen between the three genotypes. Genotypes CG + GG are not associated with concentrations of exemestane in women with Breast Neoplasms as compared to genotype CC. 27549341 1448493593